Alcohol dehydrogenase 1C (ADH1C) gene polymorphism and alcoholic liver cirrhosis risk: A meta analysis

International Journal of Clinical and Experimental Medicine

Volumn 8, Issue 7, 2015, Pages 11117-11124

  He, Lei ^a   Deng, Tao ^a   Luo, He Sheng ^a  

^a RENMIN HOSPITAL OF WUHAN UNIVERSITY   (China)

Author keywords

ADH1C; Alcoholic liver cirrhosis; Meta analysis; Polymorphism

Indexed keywords

ALCOHOL DEHYDROGENASE; ALCOHOL DEHYDROGENASE 1C; UNCLASSIFIED DRUG;

ALCOHOL LIVER CIRRHOSIS; ARTICLE; CLINICAL ASSESSMENT; GENE FREQUENCY; GENETIC ASSOCIATION; GENETIC HETEROGENEITY; GENETIC POLYMORPHISM; GENETIC VARIABILITY; GENOTYPE; HUMAN; META ANALYSIS; POLYMERASE CHAIN REACTION; RESTRICTION FRAGMENT LENGTH POLYMORPHISM;

EID: 84940662527     PISSN: None     EISSN: 19405901     Source Type: Journal    
DOI: None     Document Type: Article

References (34)

1. Rehm J, Mathers C, Popova S, Thavorncharoen-sap M, Teerawattananon Y, Patra J. Global burden of disease and injury and economic cost attributable to alcohol use and alcohol-use disorders. Lancet 2009; 373: 2223-2233.
2. O'Shea RS, Dasarathy S, McCullough AJ. Alcoholic liver disease. Hepatology 2010; 51: 307-328.
3. Kim WR, Brown RS Jr, Terrault NA, EI-Serag H. Burden of liver disease in the United States: summary of a workshop. Hepatology 2002; 36: 227-242.
4. Stickel F, Hampe J. Genetic determinants of alcoholic liver disease. Gut 2012; 61: 150-159.
5. Duester G, Farres J, Felder MR, Holmes RS, Hoog JO, Pares X, Plabb BV, Yin SJ, Jornvall H. Recommended nomenclature for the vertebrate alcohol dehydrogenase gene family. Biochem Pharmacol 1999; 58: 389-395.
6. Bosron WF, Lumeng L, Li TK. Genetic polymorphism of enzymes of alcohol metabolism and susceptibility to alcoholic liver disease. Mol Aspects Med 1988; 10: 147-158.
7. Edenberg HJ. The genetics of alcohol metabolism: role of alcohol dehydrogenase and aldehyde dehydrogenase variants. Alcohol Res Health 2007; 30: 5-13.
8. Höög JO, Hedén LO, Larsson K, Jörnvall H, von Bahr-Lindström H. The gamma 1 and gamma 2 subunits of human liver alcohol dehydrogenase. cDNA structures, two amino acid replacements, and compatibility with changes in the enzymatic properties. Eur J Biochem 1986; 159: 215-218.
9. Bosron WF, Ehrig T, Li TK. Genetic factors in alcohol metabolism and alcoholism. Semin Liver Dis 1993; 13: 126-135.
10. Borràs E, Coutelle C, Rosell A, Fernández-Muixi F, Broch M, Crosas B, Hjelmqvist L, Lorenzo A, Gutiérrez C, Santos M, Szczepanek M, Heilig M, Quattrocchi P, Farrés J, Vidal F, Richart C, Mach T, Bogdal J, Jörnvall H, Seitz HK, Couzigou P, Parés X. Genetic polymorphism of alcohol dehydrogenase in europeans: the ADH2*2 allele decreases the risk for alcoholism and is associated with ADH3*1. Hepatology 2000; 31: 984-989.
11. Chao YC, Liou SR, Chung YY, Tang HS, Hsu CT, Li TK, Yin SJ. Polymorphism of alcohol and aldehyde dehydrogenase genes and alcoho-lic cirrhosis in Chinese patients. Hepatology 1994; 19: 360-366.
12. Chao YC, Young TH, Tang HS, Hsu CT. Alcoholism and alcoholic organ damage and genetic polymorphisms of alcohol metabolizing enzymes in Chinese patients. Hepatology 1997; 25: 112-117.
13. Chao YC, Wang LS, Hsieh TY, Chu CW, Chang FY, Chu HC. Chinese alcoholic patients with esophageal cancer are genetically different from alcoholics with acute pancreatitis and liver cirrhosis. Am J Gastroenterol 2000; 95: 2958-2964.
14. Cichoz-Lach H, Partycka J, Nesina I, Celinski K, Slomka M, Wojcierowski J. Alcohol dehydrogenase and aldehyde dehydrogenase gene polymorphism in alcohol liver cirrhosis and alcohol chronic pancreatitis among Polish individuals. Scand J Gastroenterol 2007; 42: 493-498.
15. Couzigou P, Fleury B, Groppi A, Cassaigne A, Begueret J, Iron A. Genotyping study of alcohol dehydrogenase class I polymorphism in French patients with alcoholic cirrhosis. The French Group for Research on Alcohol and Liver. Alcohol Alcohol 1990; 25: 623-626.
16. Day CP, Bashir R, James OF, Bassendine MF, Crabb DW, Thomasson HR, Li TK, Edenberg HJ. Investigation of the role of polymorphisms at the alcohol and aldehyde dehydrogenase loci in genetic predisposition to alcohol-related end-organ damage. Hepatology 1991; 14: 798-801.
17. Frenzer A, Butler WJ, Norton ID, Wilson JS, Apte MV, Pirola RC, Ryan P, Roberts-Thomson IC. Polymorphism in alcohol-metabolizing enzymes, glutathione S-transferases and apolipoprotein E and susceptibility to alcohol-induced cirrhosis and chronic pancreatitis. J Gastroenterol Hepatol 2002; 17: 177-182.
18. Homann N, Stickel F, König IR, Jacobs A, Junghanns K, Benesova M, Schuppan D, Himsel S, Zuber-Jerger I, Hellerbrand C, Ludwig D, Caselmann WH, Seitz HK. Alcohol dehydrogenase 1C.*1 allele is a genetic marker for alcohol-associated cancer in heavy drinkers. Int J Cancer 2006; 118: 1998-2002.
19. Khan AJ, Husain Q, Choudhuri G, Parmar D. Association of polymorphism in alcohol dehydrogenase and interaction with other genetic risk factors with alcoholic liver cirrhosis. Drug Alcohol Depend 2010; 109: 190-197.
20. Kim MS, Lee DH, Kang HS, Park HS, Jung S, Lee JW, Kwon KS, Kim PS, Kim HG, Shin YW, Kim YS, Baek I, Lee MS. Genetic polymorphisms of alcohol-metabolizing enzymes and cytokines in patients with alcohol induced pancreatitis and alcoholic liver cirrhosis. Korean J Gastroenterol 2004; 43: 355-363.
21. Lee HC, Lee HS, Jung SH, Yi SY, Jung HK, Yoon JH, Kim CY. Association between polymorphisms of ethanol-metabolizing enzymes and susceptibility to alcoholic cirrhosis in a Korean male population. J Korean Med Sci 2001; 16: 745-750.
22. Monzoni A, Masutti F, Saccoccio G, Bellentani S, Tiribelli C, Giacca M. Genetic determinants of ethanol-induced liver damage. Mol Med 2001; 7: 255-262.
23. Poupon RE, Nalpas B, Coutelle C, Fleury B, Couzigou P, Higueret D. Polymorphism of alcohol dehydrogenase, alcohol and aldehyde dehydrogenase activities: implication in alcoholic cirrhosis in white patients. The French Group for Research on Alcohol and Liver. Hepatology 1992; 15: 1017-1022.
24. Sun L, König IR, Jacobs A, Seitz HK, Junghanns K, Wagner T, Ludwig D, Jacrobs A, Homann N. Mean corpuscular volume and ADH1C genotype in white patients with alcohol-associated diseases. Alcohol Clin Exp Res 2005; 29: 788-793.
25. Vidal F, Lorenzo A, Auguet T, Olona M, Broch M, Gutiérrez C, Aguilar C, Estupiñà P, Santos M, Richart C. Genetic polymorphisms of ADH2, ADH3, CYP4502E1Dra-I and Pst-I, and ALDH2 in Spanish men: lack of association with alcoholism and alcoholic liver disease. J Hepatol 2004; 41: 744-750.
26. Cichoz-Lach H, Partycka J, Nesina I, Celinski K, Słomka M, Wojcierowski J. Genetic polymorphism of alcohol dehydrogenase 3 in alcohol liver cirrhosis and in alcohol chronic pancreatitis. Alcohol 2006; 41: 14-7.
27. Cichoz-Lach H, Partycka J, Nesina I, Wojciero-wski J, Słomka M, Celiński K. Genetic polymorphism of alcohol dehydrogenase 3 in digestive tract alcohol damage. Hepatogastroenterology 2007; 54: 1222-1227.
28. Lorenzo A, Auguet T, Vidal F, Broch M, Olona M, Gutiérrez C, López-Dupla M, Sirvent JJ, Quer JC, Santos M, Richart C. Polymorphisms of alcohol-metabolizing enzymes and the risk for alcoholism and alcoholic liver disease in Caucasian Spanish women. Drug Alcohol Depend 2006; 84: 195-200.
29. Lau J, Ioannidis JP, Schmid CH. Quantitative synthesis in systematic reviews. Ann Intern Med 1997; 127: 820-826.
30. Mantel N, Haenszel W. Statistical aspects of the analysis of data from retrospective studies of disease. J Natl Cancer Inst 1959; 22: 719-748.
31. DerSimonian R, Laird N. Meta-analysis in clinical trials. Control Clin Trials 1986; 7: 177-88.
32. Begg CB, Mazumdar M. Operating characteristics of a rank correlation test for publication bias. Biometrics 1994; 50: 1088-1101.
33. Egger M, Davey Smith G, Schneider M, Minder C. Bias in meta-analysis detected by a simple, graphical test. BMJ 1997; 315: 629-634.
34. Yokoyama A, Tsutsumi E, Imazeki H, Suwa Y, Nakamura C, Yokoyama T. Polymorphisms of alcohol dehydrogenase-1B and aldehyde dehydrogenase-2 and the blood and salivary ethanol and acetaldehyde concentrations of Japanese alcoholic men. Alcohol Clin Exp Res 2010; 34: 1246-1256.