The effects of phosphatidylserine and omega-3 fatty acid-containing supplement on late life depression

Mental Illness

Volumn 7, Issue 1, 2015, Pages 7-11

  Komori, Teruhisa ^a  

^a MIE UNIVERSITY   (Japan)

Author keywords

Cortisol; HAM D; Late life depression; Omega 3 fatty acids; Phosphatidylserine

Indexed keywords

ALPHA TOCOTRIENOL PLUS ASTAXANTHIN PLUS DOCOSAHEXAENOIC ACID PLUS DOCOSAPENTAENOIC ACID PLUS GAMMA LINOLENIC ACID PLUS ICOSAPENTAENOIC ACID PLUS PHOSPHATIDYLSERINE; ANTIDEPRESSANT AGENT; HYDROCORTISONE; MULTIVITAMIN; UNCLASSIFIED DRUG;

AGED; ARTICLE; CIRCADIAN RHYTHM; CLINICAL ARTICLE; CONTROLLED STUDY; DIET SUPPLEMENTATION; FEMALE; HAMILTON DEPRESSION RATING SCALE; HUMAN; LATE LIFE DEPRESSION; MALE; SALIVA LEVEL; TREATMENT DURATION; TREATMENT RESPONSE;

EID: 84940661064     PISSN: 20367457     EISSN: 20367465     Source Type: Journal    
DOI: 10.4081/mi.2015.5647     Document Type: Article

References (43)

1. Blusztajn JK, Richardson UI, Liscovitch M, et al. Phospholipids in cellular survival and growth In: Hanin I, Ansel GB, eds. Lecithin: technological, biological, and therapeutic aspects. New York: Plenum Press; 1987. pp 85-9.
2. McDaniel MA, Maier SF, Einstein GO. Brain-specific nutrients: a memory cure? Nutrition 2003;19:957-75.
3. Pascale A, Govoni S, Battaini F. Age-related alterations of PKC, a key enzyme in memory processes: physical and pathological examples. Mol Neurobiol 1998;16:49-53.
4. No authors listed. Phosphatidylserine. Monograph. Altern Med Rev 2008;13:245-7.
5. Amaducci L, SMID Group. Phosphatidylserine in the treatment of Alzheimer's disease. Results of a multicentric study. Psychopharmacol Bull 1988;24:130-6.
6. Cenacchi T, Bertoldin T, Farina C, et al. Cognitive devline in the elderly: a doubleblind, placebo-controlled multicenter study on the efficacy of phosphatidylserine administration. Aging Clin Exp Res 1993;5:123-33.
7. Crook TH, Tinklenberg J, Yesavage J, et al. Effects of phosphatidylserine in age-associated memory impairment. Neurol 1991;41:644-9.
8. Jorissen BL, Brouns F, Van Boxtel MP, et al. The influence of soy-derived phosphatidylserine on conition in age-associated memory impairment. Nutr Neurosci 2001;4:121-34.
9. Kato-Kataoka A, Sakai M, Ebina R, et al. Soybean-derived phosphatidylserine improves memory function of the elderly Japanese subjects with memory complaints. J Clin Biochem Nutr 2010;47:246-55.
10. Moeteleone P, Beinat L, Tanzillo C, et al. Effects of phosphatidylserine on the neuroendocrine response to physical stress in humans. Neuroendocrinology 1990;52:243-8.
11. Monteleone P, Maj M, Beinat L, et al. Blunting by chronic phosphatidylserine administration of the stress-induced activation of the hypothalamo-pituitary-adrenal axis in healthy men. Eur J Clin Pharmacol 1992;42:385-8.
12. Kidd PM. A review of nutrients and botanicals in the integrative management of cognitive dysfunction. Altern Med Rev 1999;4:144-61.
13. Maggioni M, Picotti GB, Bondiolotti GP, et al. Effects of phosphatidylserine therapy in geriatric patients with depressive disorders. Acta Psychiatr Scand 1990;81:265-70.
14. Brambilla F, Maggioni M. Blood levels of cytokines in elderly patients with major depressive disorder. Acta Psychiatr Scand 1998;97:309-13
15. Kidd PA. Omega-3 DHA and EPA for cognition, behavior, and mood: clinical findings and structural-functional synergies with cell membrane phospholipids. Altern Med Rev 2007;12:207-27.
16. Richardson AJ. Omega-3 fatty acids in ADHD and related neurodevelopmental disorders. Int Rev Psychiatry 2006;18:155-72.
17. Freund-Levi Y, Eriksdotter-Jonhagen M, Cederholm T, et al. Omega-3 fatty acid treatment in 174 parients with mild to moderate Alzheimer disease: omegAD study: a randomized double-blind trial. Arch Neurol 2006;63:1402-8.
18. Sontrop J, Campbell MK. Omega-3 polyunsaturated fatty acids and depression: a review of the evidence and a methodological critique. Prev Med 2006;42:4-13.
19. Nemets H, Nemets B, Apter A, et al. Omefa-3 treatment of childhood depression: a controlled, double-blind study. Am J Psychiatry 2006;163:1098-100.
20. Anthony JC, LeResche L, Niaz U, et al. Limits of the mini-mental state as a screening test for dementia and delirium among hospital patients. Psychol Med 1982;12:397-408.
21. Stetler C, Miller GE. Depression and hypothalamoc- pituitary-adrenal activation: a quantitative summary of four decades of research. Psychosom Med 2011;73:114-26.
22. Monteleone P, Beinat L, Tanzillo C, et al. Effects of phosphatidylserine on the neuroendocrine response to physical stress in humans. Neuroendocrinology 1990;52;243-8.
23. Monteleone P, Maj M, Beinat L, et al. Blunting by chronic phosphatidylserine administration oh the stress-induced activation of the hypothalamo-pituitary-adrenal axis in healthy men. Eur J Clin Pharmacol 1992;42:385-8.
24. Castilho JC, Perry JC, Andreatini R, et al. Phosphatidylserine: an antidepressive or a cognitive enhancer? Prog Neuropsychopharmacol Biol Psychiatry 2004;28:731-8.
25. Salvador GA, López FM, Giusto NM. Agerelated changes in central nervous system Phosphatidylserine decarboxylase activity. J Neurosci Res 2002;70:283-9.
26. Lynch RD. Utilization of polyunsaturated fatty acids by human diploid cells aging in vityo. Lipids 1980;15:412-20.
27. Stubbs CD, Smith AD. The modification of mammalian membrane polyunsaturated fatty acid composition in relation to membrane fluidity and function. Biochim Biophys Acta 1984;779:89-137.
28. Kaibuchi K, Takay Y, Nishizuka Y. Cooperative roles of various membrane phospholipids in the activation of calciumactivated, phospholipids-dependent protein kinase. J Biol Chem 1981;256:7146-9.
29. Tsakiris S, Deliconstantios G. Influence of phosphatidylserine on (Na+/K+)-stimulated ATPase and acetylcholinesterase activities of dog brain synaptosomal plasma membranes. Biochem J 1984;220,301-7.
30. Specht SC, Robinson JD. Stimulation of the (Na+/K+)-dependent adenosine triphosphatase by amino acids and phosphatidylserine: chelation of trace metal inhibitors. Arch Biochem Biophys 1973;154:314-23.
31. Vannucchi MG, Casamenti F, Pepeu G. Decrease of acetylcholine release from cortical slices in aged rats: investigations into its reversal by Phosphatidylserine. J Neurochem 1990;55:819-25.
32. Pepeu G, Giovanelli L, Giovaaini MG, et al. Effects of Phosphatidylserine on cortical acetylcholine release and calcium uptake in adult and aging rats. In: Horrocks LA, Freysz L, Toffano G, eds. Phospholipid research and the nervous system. Biochemical and molecular pharmacology. Padova: Liviana Press; 1996. pp 265-271.
33. Casamenti F, Mantovani P, Amaducchi L, et al. Effect of phosphatidylserine on acetylcholine output from the cerebral cortex of the rat. J Neurochem 1979;32:529-33.
34. Casamenti F, Scali C, Pepeu G. Phosphatidylserine reverses the agedependent decrease in cortical acetylcholine release: a microdialysis study. Eur J Pharmacol 1991;194:11-6.
35. Mazzari S, Battistella A. Phosphatidylserine effects on dopamine release from striatum synaptosomes. In: Benedetta C, Balazs R, Gombos G, Porcellani G, eds. Multidisciplinary approach to brain development. Amsterdam: Elsevier; 1980. pp 569-570.
36. Cohen SA, Müller WE. Age-related alterations of NMDA-receptor properties in the mouse forebrain: partial restoration by chronic phosphatidylserine treatment. Brain Res 1992;584:174-80.
37. Warner-Schmidt JL, Duman RS. Hippocampal neurogenesis: opposing effects of stress and antidepressant treatment. Hippocampus 2006;16:239-49.
38. Nunzi MG, Milan F, Guidolin D, et al. Dendritic spine loss in hippocampus of aged rats. Effect og brain Phosphatidylserine administration. Neurobiol Aging 1987;8:501-10.
39. Sinclair AJ, Begg D, Mathi M, et al. Omega 3 fatty acids and the brain: review of studies in depression. Asia Pac J Clin Nutr 2007;16:391-7.
40. Huang SY, Yang HT, Chiu CC, et al. Omega-3 fatty acids on the forced-swimming test. J Psychiatr Res 2008;42:58-63.
41. Liu X, Osawa T. Astaxanthin protects neuronal cells against oxidative damage and is a potent candidate for brain food. Forum Nutr 2009;61:129-35.
42. Sen CK, Khanna S, Rink C, Roy S. Tocotrienols: the emerging face of natural vitamin E. Vitam Horm 2007;76:203-61.
43. Sen CK, Rink C, Khanns S. Palm oil-derived natural vitamin E alpha-tocotrienol in brain health and disease. J Am Coll Nutr 2010;29:314S-23S.