Restless Leg Syndrome Across the Globe: Epidemiology of the Restless Legs Syndrome/Willis-Ekbom Disease

Sleep Medicine Clinics

Volumn 10, Issue 3, 2015, Pages 189-205

  Koo, Brian B ^a,b  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b VA CONNECTICUT HEALTHCARE SYSTEM   (United States)

Author keywords

Epidemiology; Restless legs syndrome; RLS; Willis Ekbom disease; World

Indexed keywords

25 HYDROXYVITAMIN D; ALPHA INTERMEDIN; MELANOCORTIN 1 RECEPTOR;

AFRICA; AGE DISTRIBUTION; ARTICLE; ASIA; CLINICAL FEATURE; CULTURAL FACTOR; DIFFERENTIAL DIAGNOSIS; DISEASE CLASSIFICATION; ENVIRONMENTAL FACTOR; EPIDEMIOLOGICAL DATA; ETHNIC DIFFERENCE; EUROPE; GENE FUNCTION; GENE MUTATION; GENETIC VARIABILITY; GEOGRAPHIC DISTRIBUTION; HEREDITY; HUMAN; NORTH AMERICA; PERIODIC LIMB MOVEMENT DISORDER; PREVALENCE; PRIORITY JOURNAL; RADIATION EXPOSURE; RESTLESS LEGS SYNDROME; SEX DIFFERENCE; SINGLE NUCLEOTIDE POLYMORPHISM; SOUTH AMERICA; VITAMIN BLOOD LEVEL; GENETICS; INTERNATIONAL COOPERATION;

HUMANS; INTERNATIONALITY; PREVALENCE; RESTLESS LEGS SYNDROME;

EID: 84940459618     PISSN: 1556407X     EISSN: 15564088     Source Type: Journal    
DOI: 10.1016/j.jsmc.2015.05.004     Document Type: Review

References (85)

1. T. Willis The London practice of physic 1685 Bassett and Crooke London
2. X. Ji Neike zhaiyao (Internal summary). 1529 AD. From modern reproduction 1985 Jiang Su Scientific and Technology Publishing House Nanjing (China)
3. K. Ekbom Asthenia crurum paraesthetica ('Irritable legs') Acta Med Scand 118 1944 197 209
4. R.P. Allen, A.S. Walters, J. Montplaisir, and et al. Restless legs syndrome prevalence and impact: REST general population study Arch Intern Med 165 2005 1286 1292
5. A.S. Winkler, A. Trendafilova, M. Meindl, and et al. Restless legs syndrome in a population of northern Tanzania: a community-based study Mov Disord 25 2010 596 601
6. S.J. Cho, J.P. Hong, B.J. Hahm, and et al. Restless legs syndrome in a community sample of Korean adults: prevalence, impact on quality of life, and association with DSM-IV psychiatric disorders Sleep 32 2009 1069 1076
7. G.G. Persi, J.L. Etcheverry, C. Vecchi, and et al. Prevalence of restless legs syndrome: a community-based study from Argentina Parkinsonism Relat Disord 15 2009 461 465
8. J. Ulfberg, B. Bjorvatn, L. Leissner, and et al. Comorbidity in restless legs syndrome among a sample of Swedish adults Sleep Med 8 2007 768 772
9. A.S. Walters Toward a better definition of the restless legs syndrome. The International Restless Legs Syndrome Study Group Mov Disord 10 1995 634 642
10. R.P. Allen, D. Picchietti, W.A. Hening, and et al. Restless legs syndrome: diagnostic criteria, special considerations, and epidemiology. A report from the restless legs syndrome diagnosis and epidemiology workshop at the National Institutes of Health Sleep Med 4 2003 101 119
11. R.P. Allen, D.L. Picchietti, D. Garcia-Borreguero, and et al. Restless legs syndrome/Willis-Ekbom disease diagnostic criteria: updated International Restless Legs Syndrome Study Group (IRLSSG) consensus criteria - history, rationale, description, and significance Sleep Med 15 2014 860 873
12. American Academy of Sleep Medicine International classification of sleep disorders 3rd edition 2014 American Academy of Sleep Medicine Darien (IL)
13. American Psychiatric Association Diagnostic and statistical manual of mental disorders: DSM-5 2013 American Psychiatric Association. Washington, DC
14. C. Burtscher, A. Baxmann, J. Kassubek, and et al. Prevalence of restless legs syndrome in an urban population of eastern Africa (Tanzania) J Neurol Sci 346 2014 121 127
15. Y.W. Cho, W.C. Shin, C.H. Yun, and et al. Epidemiology of restless legs syndrome in Korean adults Sleep 31 2008 219 223
16. W.H. Kim, B.S. Kim, S.K. Kim, and et al. Restless legs syndrome in older people: a community-based study on its prevalence and association with major depressive disorder in older Korean adults Int J Geriatr Psychiatry 27 2012 565 572
17. J. Kim, C. Choi, K. Shin, and et al. Prevalence of restless legs syndrome and associated factors in the Korean adult population: the Korean Health and Genome Study Psychiatry Clin Neurosci 59 2005 350 353
18. Y.M. Park, H.J. Lee, S.G. Kang, and et al. Prevalence of idiopathic and secondary restless legs syndrome in Korean Women Gen Hosp Psychiatry 32 2010 164 168
19. M.M. Weissman, R.C. Bland, G.J. Canino, and et al. Cross-national epidemiology of major depression and bipolar disorder JAMA 276 1996 293 299
20. J. Helliwell, R. Layard, and J. Sachs World happiness report 2013 2013 UN Sustainable Development Solutions Network New York
21. S.M. Chang, B.J. Hahm, J.Y. Lee, and et al. Cross-national difference in the prevalence of depression caused by the diagnostic threshold J Affect Disord 106 2008 159 167
22. T. Nomura, Y. Inoue, M. Kusumi, and et al. Prevalence of restless legs syndrome in a rural community in Japan Mov Disord 23 2008 2363 2369
23. T. Kageyama, M. Kabuto, H. Nitta, and et al. Prevalences of periodic limb movement-like and restless legs-like symptoms among Japanese adults Psychiatry Clin Neurosci 54 2000 296 298
24. E. Yokoyama, Y. Saito, Y. Kaneita, and et al. Association between subjective well-being and sleep among the elderly in Japan Sleep Med 9 2008 157 164
25. Y. Tsuboi, A. Imamura, M. Sugimura, and et al. Prevalence of restless legs syndrome in a Japanese elderly population Parkinsonism Relat Disord 15 2009 598 601
26. S. Rangarajan, and G.A. D'Souza Restless legs syndrome in an Indian urban population Sleep Med 9 2007 88 93
27. N.H. Chen, L.P. Chuang, C.T. Yang, and et al. The prevalence of restless legs syndrome in Taiwanese adults Psychiatry Clin Neurosci 64 2010 170 178
28. L.H. Li, H.B. Chen, L.P. Zhang, and et al. A community-based investigation on restless legs syndrome in a town in China Sleep Med 13 2012 342 345
29. J.F. Ma, X.Y. Xin, L. Liang, and et al. Restless legs syndrome in Chinese elderly people of an urban suburb in Shanghai: a community-based survey Parkinsonism Relat Disord 18 2012 294 298
30. X. Yan, W.D. Wang, A.S. Walters, and et al. Traditional Chinese medicine herbal preparations in restless legs syndrome (RLS) treatment: a review and probable first description of RLS in 1529 Sleep Med Rev 16 2012 509 518
31. S. Sevim, O. Dogu, H. Kaleagasi, and et al. Correlation of anxiety and depression symptoms in patients with restless legs syndrome: a population based survey J Neurol Neurosurg Psychiatry 75 2004 226 230
32. S. Erer, N. Karli, M. Zarifoglu, and et al. The prevalence and clinical features of restless legs syndrome: a door to door population study in Orhangazi, Bursa in Turkey Neurol India 57 2009 729 733
33. M. Tasdemir, H. Erdogan, U.T. Boru, and et al. Epidemiology of restless legs syndrome in Turkish adults on the western Black Sea coast of Turkey: a door-to-door study in a rural area Sleep Med 11 2010 82 86
34. G.M. Hadjigeorgiou, I. Stefanidis, E. Dardiotis, and et al. Low RLS prevalence and awareness in central Greece: an epidemiological survey Eur J Neurol 14 2007 1275 1280
35. M.M. Ohayon, and T. Roth Prevalence of restless legs syndrome and periodic limb movement disorder in the general population J Psychosom Res 53 2002 547 554
36. B. Hogl, S. Kiechl, J. Willeit, and et al. Restless legs syndrome: a community-based study of prevalence, severity, and risk factors Neurology 64 2005 1920 1924
37. F.D. Vogl, I. Pichler, S. Adel, and et al. Restless legs syndrome: epidemiological and clinicogenetic study in a South Tyrolean population isolate Mov Disord 21 2006 1189 1195
38. S. Celle, F. Roche, J. Kerleroux, and et al. Prevalence and clinical correlates of restless legs syndrome in an elderly French population: the synapse study J Gerontol A Biol Sci Med Sci 65 2010 167 173
39. F. Tison, A. Crochard, D. Leger, and et al. Epidemiology of restless legs syndrome in French adults: a nationwide survey: the INSTANT Study Neurology 65 2005 239 246
40. A.J. Rothdach, C. Trenkwalder, J. Haberstock, and et al. Prevalence and risk factors of RLS in an elderly population: the MEMO study. Memory and Morbidity in Augsburg Elderly Neurology 54 2000 1064 1068
41. K. Berger, J. Luedemann, C. Trenkwalder, and et al. Sex and the risk of restless legs syndrome in the general population Arch Intern Med 164 2004 196 202
42. S. Happe, M. Vennemann, S. Evers, and et al. Treatment wish of individuals with known and unknown restless legs syndrome in the community J Neurol 255 2008 1365 1371
43. R. Rijsman, A.K. Neven, W. Graffelman, and et al. Epidemiology of restless legs in The Netherlands Eur J Neurol 11 2004 607 611
44. T. Pekmezovic, J. Jovic, M. Svetel, and et al. Prevalence of restless legs syndrome among adult population in a Serbian district: a community-based study Eur J Epidemiol 28 2013 927 930
45. B. Benediktsdottir, C. Janson, E. Lindberg, and et al. Prevalence of restless legs syndrome among adults in Iceland and Sweden: lung function, comorbidity, ferritin, biomarkers and quality of life Sleep Med 11 2010 1043 1048
46. A.K. Juuti, E. Laara, U. Rajala, and et al. Prevalence and associated factors of restless legs in a 57-year-old urban population in northern Finland Acta Neurol Scand 122 2010 63 69
47. B. Bjorvatn, L. Leissner, J. Ulfberg, and et al. Prevalence, severity and risk factors of restless legs syndrome in the general adult population in two Scandinavian countries Sleep Med 6 2005 307 312
48. J. Ulfberg, B. Nystrom, N. Carter, and et al. Prevalence of restless legs syndrome among men aged 18 to 64 years: an association with somatic disease and neuropsychiatric symptoms Mov Disord 16 2001 1159 1163
49. J. Ulfberg, B. Nystrom, N. Carter, and et al. Restless legs syndrome among working-aged women Eur Neurol 46 2001 17 19
50. J.E. Broman, L. Mallon, and J. Hetta Restless legs syndrome and its relationship with insomnia symptoms and daytime distress: epidemiological survey in Sweden Psychiatry Clin Neurosci 62 2008 472 475
51. J. Wesstrom, S. Nilsson, I. Sundstrom-Poromaa, and et al. Restless legs syndrome among women: prevalence, co-morbidity and possible relationship to menopause Climacteric 11 2008 422 428
52. K.-A. Ekbom Restless legs Acta Med Scand 158 suppl 1945 1 123
53. G.E. Simon, M. VonKorff, M. Piccinelli, and et al. An international study of the relation between somatic symptoms and depression N Engl J Med 341 1999 1329 1335
54. B.B. Koo, P. Feng, J. Dostal, and et al. Alpha-melanocyte stimulating hormone and adrenocorticotropic hormone: an alternative approach when thinking about restless legs syndrome? Mov Disord 23 2008 1234 1242
55. Z. Abdel-Malek, I. Suzuki, A. Tada, and et al. The melanocortin-1 receptor and human pigmentation Ann N Y Acad Sci 885 1999 117 133
56. N.G. Jablonski, and G. Chaplin The evolution of human skin coloration J Hum Evol 39 2000 57 106
57. B.B. Koo Restless legs syndrome: relationship between prevalence and latitude Sleep Breath 16 2012 1237 1245
58. D.G. Ingram, and D.T. Plante Seasonal trends in restless legs symptomatology: evidence from internet search query data Sleep Med 14 2013 1364 1368
59. H. Balaban, O.K. Yildiz, G. Cil, and et al. Serum 25-hydroxyvitamin D levels in restless legs syndrome patients Sleep Med 13 2012 953 957
60. M. Miranda, F. Araya, J.L. Castillo, and et al. Restless legs syndrome: a clinical study in adult general population and in uremic patients Rev Med Chil 129 2001 179 186
61. P.R. Castillo, J. Kaplan, S.C. Lin, and et al. Prevalence of restless legs syndrome among native South Americans residing in coastal and mountainous areas Mayo Clin Proc 81 2006 1345 1347
62. P.R. Castillo, R.M. Mera, P.A. Fredrickson, and et al. Psychological distress in patients with restless legs syndrome (Willis-Ekbom disease): a population-based door-to-door survey in rural Ecuador BMC Res Notes 7 2014 911
63. A.L. Eckeli, L.L. Gitai, F. Dach, and et al. Prevalence of restless legs syndrome in the rural town of Cassia dos Coqueiros in Brazil Sleep Med 12 2011 762 767
64. G.J. Lavigne, and J.Y. Montplaisir Restless legs syndrome and sleep bruxism: prevalence and association among Canadians Sleep 17 1994 739 743
65. C.L. Froese, A. Butt, A. Mulgrew, and et al. Depression and sleep-related symptoms in an adult, indigenous, North American population J Clin Sleep Med 4 2008 356 361
66. B. Phillips, T. Young, L. Finn, and et al. Epidemiology of restless legs symptoms in adults Arch Intern Med 160 2000 2137 2141
67. B. Phillips, W. Hening, P. Britz, and et al. Prevalence and correlates of restless legs syndrome: results from the 2005 National Sleep Foundation Poll Chest 129 2006 76 80
68. H.B. Lee, W.A. Hening, R.P. Allen, and et al. Race and restless legs syndrome symptoms in an adult community sample in east Baltimore Sleep Med 7 2006 642 645
69. J.W. Winkelman, L. Finn, and T. Young Prevalence and correlates of restless legs syndrome symptoms in the Wisconsin Sleep Cohort Sleep Med 7 2006 545 552
70. J.W. Winkelman, E. Shahar, I. Sharief, and et al. Association of restless legs syndrome and cardiovascular disease in the Sleep Heart Health Study Neurology 70 2008 35 42
71. X. Gao, M.A. Schwarzschild, H. Wang, and et al. Obesity and restless legs syndrome in men and women Neurology 72 2009 1255 1261
72. S. Ram, H. Seirawan, S.K. Kumar, and et al. Prevalence and impact of sleep disorders and sleep habits in the United States Sleep Breath 14 2010 63 70
73. K. Sawanyawisuth, L.A. Palinkas, S. Ancoli-Israel, and et al. Ethnic differences in the prevalence and predictors of restless legs syndrome between Hispanics of Mexican descent and non-Hispanic Whites in San Diego county: a population-based study J Clin Sleep Med 9 2013 47 53
74. R.P. Allen, M. Bharmal, and M. Calloway Prevalence and disease burden of primary restless legs syndrome: results of a general population survey in the United States Mov Disord 26 2011 114 120
75. N.G. Kutner, and D.L. Bliwise Restless legs complaint in African-American and Caucasian hemodialysis patients Sleep Med 3 2002 497 500
76. A.C. Winter, M. Schurks, R.J. Glynn, and et al. Restless legs syndrome and risk of incident cardiovascular disease in women and men: prospective cohort study BMJ Open 2 2012 e000866
77. Y. Li, A.S. Walters, S.E. Chiuve, and et al. Prospective study of restless legs syndrome and coronary heart disease among women Circulation 126 2012 1689 1694
78. A. Szentkiralyi, H. Volzke, W. Hoffmann, and et al. Multimorbidity and the risk of restless legs syndrome in 2 prospective cohort studies Neurology 82 2014 2026 2033
79. G. Marin, F. Sabogal, B.V. Marin, and et al. Development of a short acculturation scale for hispanics Hisp J Behav Sci 9 1987 183 205
80. W.A. Hening, R.P. Allen, M. Washburn, and et al. Validation of the Hopkins telephone diagnostic interview for restless legs syndrome Sleep Med 9 2008 283 289
81. R.P. Allen, B.J. Burchell, B. MacDonald, and et al. Validation of the self-completed Cambridge-Hopkins questionnaire (CH-RLSq) for ascertainment of restless legs syndrome (RLS) in a population survey Sleep Med 10 2009 1097 1100
82. H. Stefansson, D.B. Rye, A. Hicks, and et al. A genetic risk factor for periodic limb movements in sleep N Engl J Med 357 2007 639 647
83. J. Winkelmann, B. Schormair, P. Lichtner, and et al. Genome-wide association study of restless legs syndrome identifies common variants in three genomic regions Nat Genet 39 2007 1000 1006
84. B. Schormair, D. Kemlink, D. Roeske, and et al. PTPRD (protein tyrosine phosphatase receptor type delta) is associated with restless legs syndrome Nat Genet 40 2008 946 948
85. M.K. Kim, Y.W. Cho, W.C. Shin, and et al. Association of restless legs syndrome variants in Korean patients with restless legs syndrome Sleep 36 2013 1787 1791