Obesity and restless legs syndrome in men and women

Neurology

Volumn 72, Issue 14, 2009, Pages 1255-1261

  Gao, Xiang ^a,b   Schwarzschild, Michael A ^c   Wang, Hao ^b   Ascherio, Alberto ^a,b  

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

^b HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

^c MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIDEPRESSANT AGENT;

ABDOMINAL OBESITY; ADULT; ARTHRITIS; ARTICLE; BODY MASS; CLINICAL ASSESSMENT; CONTROLLED STUDY; DISEASE ASSOCIATION; FEMALE; GROUPS BY AGE; HUMAN; MAJOR CLINICAL STUDY; MALE; OBESITY; PHOBIA; PREGNANCY; PREVALENCE; PRIORITY JOURNAL; RESTLESS LEGS SYNDROME; RISK FACTOR; SMOKING HABIT; WAIST CIRCUMFERENCE; WEIGHT GAIN; ABDOMINAL FAT; ADOLESCENT; AGED; CIRCADIAN RHYTHM SLEEP DISORDER; COHORT ANALYSIS; COMPARATIVE STUDY; HYPERTENSION; MIDDLE AGED; NURSE; PHYSIOLOGY; QUESTIONNAIRE; SEXUAL DEVELOPMENT; WAIST HIP RATIO;

ABDOMINAL FAT; ADOLESCENT; ADULT; AGED; BODY MASS INDEX; COHORT STUDIES; FEMALE; HUMANS; HYPERTENSION; MALE; MIDDLE AGED; NURSES; OBESITY; QUESTIONNAIRES; RESTLESS LEGS SYNDROME; RISK FACTORS; SEX CHARACTERISTICS; SLEEP DISORDERS, CIRCADIAN RHYTHM; WAIST-HIP RATIO; WEIGHT GAIN; YOUNG ADULT;

EID: 65249177704     PISSN: 00283878     EISSN: 1526632X     Source Type: Journal    
DOI: 10.1212/01.wnl.0000345673.35676.1c     Document Type: Article

References (30)

1. Garcia-Borreguero D, Odin P, Schwarz C. Restless legs syndrome: an overview of the current understanding and management. Acta Neurol Scand 2004;109:303-317.
2. Kushida CA. Clinical presentation, diagnosis, and quality of life issues in restless legs syndrome. Am J Med 2007; 120:S4-S12.
3. Winkelman JW, Shahar E, Sharief I, Gottlieb DJ. Association of restless legs syndrome and cardiovascular disease in the Sleep Heart Health Study. Neurology 2008;70:35-42.
4. Rothdach AJ, Trenkwalder C, Haberstock J, Keil U, Berger K. Prevalence and risk factors of RLS in an elderly population: the MEMO study: memory and morbidity in Augsburg elderly. Neurology 2000;54:1064-1068.
5. Phillips B, Hening W, Britz P, Mannino D. Prevalence and correlates of restless legs syndrome: results from the 2005 National Sleep Foundation Poll. Chest 2006;129:76-80.
6. Lopes LA, Lins C, de M, et al. Restless legs syndrome and quality of sleep in type 2 diabetes. Diabetes Care 2005;28: 2633-2636.
7. Phillips B, Young T, Finn L, Asher K, Hening WA, Purvis C. Epidemiology of restless legs symptoms in adults. Arch Intern Med 2000;160:2137-2141.
8. Allen RP, Walters AS, Montplaisir J, et al. Restless legs syndrome prevalence and impact: REST general population study. Arch Intern Med 2005;165:1286-1292.
9. Allen RP. Controversies and challenges in defining the etiology and pathophysiology of restless legs syndrome. Am J Med 2007;120:S13-21.
10. Paulus W, Trenkwalder C. Less is more: pathophysiology of dopaminergic-therapy-related augmentation in restless legs syndrome. Lancet Neurol 2006;5:878-886.
11. Wang GJ, Volkow ND, Logan J, et al. Brain dopamine and obesity. Lancet 2001;357:354-357.
12. Ohayon MM, Roth T. Prevalence of restless legs syndrome and periodic limb movement disorder in the general population. J Psychosom Res 2002;53:547-554.
13. Kim J, Choi C, Shin K, et al. Prevalence of restless legs syndrome and associated factors in the Korean adult population: the Korean Health and Genome Study. Psychiatry Clin Neurosci 2005;59:350-353.
14. Sevim S, Dogu O, Kaleagasi H, Aral M, Metin O, Camdeviren H. Correlation of anxiety and depression symptoms in patients with restless legs syndrome: a population based survey. J Neurol Neurosurg Psychiatry 2004;75:226-230.
15. RimmEB, Stampfer MJ, Colditz GA, Chute CG, Litin LB, WillettWC. Validity of self-reported waist and hip circumferences in men and women. Epidemiology 1990;1:466-473.
16. Stunkard AJ, Sorensen T, Schulsinger F. Use of the Danish Adoption Register for the study of obesity and thinness. Res Publ Assoc Res Nerv Ment Dis 1983;60:115-120.
17. Weisskopf MG, Chen H, Schwarzschild MA, Kawachi I, Ascherio A. Prospective study of phobic anxiety and risk of Parkinson's disease. Mov Disord 2003;18:646-651.
18. Berlin JA, Longnecker MP, Greenland S. Meta-analysis of epidemiologic dose-response data. Epidemiology 1993;4: 218-228.
19. Sevim S, Dogu O, Camdeviren H, et al. Unexpectedly low prevalence and unusual characteristics of RLS in Mersin, Turkey. Neurology 2003;61:1562-1569.
20. Rajaram SS, Shanahan J, Ash C, Walters AS, Weisfogel G. Enhanced external counter pulsation (EECP) as a novel treatment for restless legs syndrome (RLS): a preliminary test of the vascular neurologic hypothesis for RLS. Sleep Med 2005;6:101-106.
21. Hamdi A, Porter J, Prasad C. Decreased striatal D2 dopamine receptors in obese Zucker rats: changes during aging. Brain Res 1992;589:338-340.
22. Huang XF, Zavitsanou K, Huang X, et al. Dopamine transporter and D2 receptor binding densities in mice prone or resistant to chronic high fat diet-induced obesity. Behav Brain Res 2006;175:415-419.
23. Need AC, Ahmadi KR, Spector TD, Goldstein DB. Obesity is associated with genetic variants that alter dopamine availability. Ann Hum Genet 2006;70:293-303.
24. Abbott RD, Ross GW, White LR, et al. Midlife adiposity and the future risk of Parkinson's disease. Neurology 2002; 59:1051-1057.
25. Hu G, Jousilahti P, Nissinen A, Antikainen R, Kivipelto M, Tuomilehto J. Body mass index and the risk of Parkinson disease. Neurology 2006;67:1955-1959.
26. Chen H, Zhang SM, Schwarzschild MA, Hernan MA, Willett WC, Ascherio A. Obesity and the risk of Parkinson's disease. Am J Epidemiol 2004;159:547-555.
27. Allen RP, Picchietti D, Hening WA, Trenkwalder C, Walters AS, Montplaisi J. Restless legs syndrome: diagnostic criteria, special considerations, and epidemiology: a report from the restless legs syndrome diagnosis and epidemiology workshop at the National Institutes of Health. Sleep Med 2003;4:101-119.
28. Winkelmann J, Schormair B, Lichtner P, et al. Genomewide association study of restless legs syndrome identifies common variants in three genomic regions. Nat Genet 2007;39:1000-1006.
29. Stefansson H, Rye DB, Hicks A, et al. A genetic risk factor for periodic limb movements in sleep. N Engl J Med 2007; 357:639-647.
30. Ascherio A, Rimm EB, Giovannucci E, Willett WC, Stampfer MJ. Blood donations and risk of coronary heart disease in men. Circulation 2001;103:52-57.