Cadmium delays puberty onset and testis growth in adolescents

Clinical Endocrinology

Volumn 83, Issue 3, 2015, Pages 357-362

  Interdonato, Monica ^a   Pizzino, Gabriele ^a   Bitto, Alessandra ^a   Galfo, Federica ^a   Irrera, Natasha ^a   Mecchio, Anna ^a   Pallio, Giovanni ^a   Ramistella, Vincenzo ^b   Luca, Filippo De ^b   Santamaria, Angelo ^b   Minutoli, Letteria ^a   Marini, Herbert ^a   Squadrito, Francesco ^a   Altavilla, Domenica ^b  

^a UNIVERSITY OF MESSINA   (Italy)

^b UNIVERSITY OF MESSINA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

CADMIUM; FOLLITROPIN; INHIBIN B; LUTEINIZING HORMONE; TESTOSTERONE; INHIBIN;

ADOLESCENT; ARTICLE; CLINICAL EXAMINATION; CONTROLLED STUDY; CROSS-SECTIONAL STUDY; DELAYED PUBERTY; DEVELOPMENTAL STAGE; DEVELOPMENTAL TOXICITY; ECHOGRAPHY; FOLLITROPIN BLOOD LEVEL; HUMAN; INDUSTRIAL AREA; LUTEINIZING HORMONE BLOOD LEVEL; MAJOR CLINICAL STUDY; MALE; PATHOGENESIS; PRIORITY JOURNAL; TESTIS DEVELOPMENT; TESTIS SIZE; TESTOSTERONE BLOOD LEVEL; URINE LEVEL; BLOOD; CHILD; CLINICAL TRIAL; GROWTH, DEVELOPMENT AND AGING; HEALTH; MULTICENTER STUDY; ORGAN SIZE; PHYSIOLOGY; PUBERTY; STATISTICAL MODEL; STATISTICS AND NUMERICAL DATA; TESTIS; TIME FACTOR; URBAN POPULATION; URINE;

ADOLESCENT; CADMIUM; CHILD; CROSS-SECTIONAL STUDIES; FOLLICLE STIMULATING HORMONE; HUMANS; INHIBINS; LINEAR MODELS; LUTEINIZING HORMONE; MALE; ORGAN SIZE; PUBERTY; TESTIS; TESTOSTERONE; TIME FACTORS; URBAN HEALTH; URBAN POPULATION;

EID: 84940448175     PISSN: 03000664     EISSN: 13652265     Source Type: Journal    
DOI: 10.1111/cen.12704     Document Type: Article

References (29)

1. Ademuyiwa, O., Agarwal, R., Chandra, R., et al,. (2010) Effects of sub-chronic low-level lead exposure on the homeostasis of copper and zinc in rat tissues. Journal of Trace Elements in Medicine and Biology, 24, 207-211.
2. Kakkar, P., &, Jaffery, F.N., (2005) Biological markers for metal toxicity. Environmental Toxicology and Pharmacology, 19, 335-349.
3. Diamanti-Kandarakis, E., Bourguignon, J.P., Giudice, L.C., et al,. (2009) Endocrine-disrupting chemicals: an Endocrine Society scientific statement. Endocrine Review, 30, 293-342.
4. Mazej, Z., Al Sayegh-Petkovsek, S., &, Pokorny, B., (2010) Heavy metal concentrations in food chain of Lake Velenjsko jezero, Slovenia: an artificial lake from mining. Archives of Environmental Contamination and Toxicology, 58, 998-1007.
5. Qiao, M., Cai, C., Huang, Y., et al,. (2011) Characterization of soil heavy metal contamination and potential health risk in metropolitan region of northern China. Environmental Monitoring and Assessment, 172, 353-365.
6. Aitken, R.J., &, Baker, M.A., (2013) Causes and consequences of apoptosis in spermatozoa; contributions to infertility and impacts on development. International Journal of Developmental Biology, 57, 265-272.
7. Lafuente, A., (2013) The hypothalamic-pituitary-gonadal axis is target of cadmium toxicity. An update of recent studies and potential therapeutic approaches. Food and Chemical Toxicology, 59, 395-404.
8. Lafuente, A., Márquez, N., Pérez-Lorenzo, M., et al,. (2000) Pubertal and postpubertal cadmium exposure differentially affects the hypothalamic-pituitary-testicular axis function in the rat. Food and Chemical Toxicology, 38, 913-923.
9. Ciarrocca, M., Capozzella, A., Tomei, F., et al,. (2013) Exposure to cadmium in male urban and rural workers and effects on FSH, LH and testosterone. Chemosphere, 90, 2077-2084.
10. Interdonato, M., Bitto, A., Pizzino, G., et al,. (2014) Levels of heavy metals in adolescents living in the industrialised area of milazzo-valle del mela (northern sicily). Journal of Environmental and Public Health, 2014, 326845.
11. Pizzino, G., Bitto, A., Interdonato, M., et al,. (2014) Oxidative stress and DNA repair and detoxification gene expression in adolescents exposed to heavy metals living in the Milazzo-Valle del Mela area (Sicily, Italy). Redox Biology, 2, 686-693.
12. Tanner, J.M., &, Whitehouse, R.H., (1976) Clinical longitudinal standards for height, weight, height velocity, weight velocity, and stages of puberty. Archives of Disease in Childhood, 51, 170-179.
13. Kuczmarski, R.J., Ogden, C.L., Guo, S.S., et al,. (2002) 2000 CDC growth charts for the United States: Methods and development. National Center for Health Statistics, Vital and Health Statistics Series.
14. Umweltbundesamt (UBA). Report 2010 Health and Environmental Hygiene: German Environmental Survey (GerES). Umweltbundesamt, Berlin. http://www.uba.de
15. Health Canada. (2010) Report of human biomonitoring of environmental chemicals. Results of the Canadian Health Measures Survey Cycle 1 2007-2009, Ottawa.
16. Schulz, C., Wilhelm, M., Heudorf, U., et al,. (2012) Update of the reference and HBM values derived by the German Human Biomonitoring Commission. International Journal of Hygiene and Environmental Health, 215, 149.
17. Bernhoft, R.A., (2013) Cadmium toxicity and treatment. Scientific World Journal 2013, 394652. Review.
18. Au, W.W.,. (2002) Susceptibility of children to environmental toxic substances. International Journal of Hygiene and Environmental Health 205, 501-503. Review.
19. Ji, Y.L., Wang, H., Liu, P., et al,. (2010) Pubertal cadmium exposure impairs testicular development and spermatogenesis via disrupting testicular testosterone synthesis in adult mice. Reproductive Toxicology, 29, 176-183.
20. Liu, Q., Gu, J.H., Yuan, Y., et al,. (2013) Effect of cadmium on rat Leydig cell testosterone production and DNA integrity in vitro. Biomedical and Environmental Sciences, 26, 769-773.
21. Luca, G., Lilli, C., Bellocci, C., et al,. (2013) Toxicity of cadmium on Sertoli cell functional competence: an in vitro study. Journal of Biological Regulators & Homeostatic Agents, 27, 805-816.
22. Ohtani, K., Yanagiba, Y., Ashimori, A., et al,. (2013) Influence of injection timing on severity of cadmium-induced testicular toxicity in mice. Journal of Toxicological Sciences, 38, 145-150.
23. Wang, B., &, Du, Y., (2013) Cadmium and its neurotoxic effects. Oxidative Medicine and Cellular Longevity 2013, 898034. Review.
24. Foote, R.H., (1999) Fertility of rabbit sperm exposed in vitro to cadmium and lead. Reproductive Toxicology, 13, 443-449.
25. Lafuente, A., Márquez, N., Pérez-Lorenzo, M., et al,. (2001) Cadmium effects on hypothalamic-pituitary-testicular axis in male rats. Experimental Biology and Medicine, 226, 605-611.
26. Lafuente, A., González-Carracedo, A., Romero, A., et al,. (2004) Cadmium exposure differentially modifies the circadian patterns of norepinephrine at the median eminence and plasma LH, FSH and testosterone levels. Toxicology Letters, 146, 175-182.
27. Lafuente, A., &, Esquifino, A.I., (1999) Cadmium effects on hypothalamic activity and pituitary hormone secretion in the male. Toxicology Letters, 110, 209-218.
28. Andersson, A.M., Juul, A., Petersen, J.H., et al,. (1997) Serum inhibin B in healthy pubertal and adolescent boys: relation to age, stage of puberty, and follicle-stimulating hormone, luteinizing hormone, testosterone, and estradiol levels. Journal of Clinical Endocrinology and Metabolism., 82, 3976-3981.
29. Ho, C.K., Stoddart, M., Walton, M., et al,. (2006) Calculated free testosterone in men: comparison of four equations and with free androgen index. Annals of clinical biochemistry, 43, 389-397.