Angiotensin-converting enzyme (ACE) gene insertion/deletion polymorphism is not a risk factor for hypertension in SLE nephritis

Clinical Rheumatology

Volumn 34, Issue 9, 2015, Pages 1545-1549

  Negi, Vir S ^a   Devaraju, Panneer ^a   Gulati, Reena ^a  

^a JAWAHARLAL INSTITUTE OF POSTGRADUATE MEDICAL EDUCATION AND RESEARCH   (India)

Author keywords

ACE; Autoantibodies; Hypertension; Lupus nephritis; SLE

Indexed keywords

AUTOANTIBODY; DIPEPTIDYL CARBOXYPEPTIDASE; ACE PROTEIN, HUMAN;

ADULT; ALLELE; ARTICLE; CARDIOVASCULAR RISK; CLINICAL FEATURE; CONTROLLED STUDY; DIASTOLIC BLOOD PRESSURE; DISEASE ACTIVITY; DNA POLYMORPHISM; ETHNICITY; FEMALE; GENETIC RISK; GENETIC SUSCEPTIBILITY; GENOTYPE; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; HYPERTENSION; INDEL MUTATION; INDIAN; LUPUS ERYTHEMATOSUS NEPHRITIS; MAJOR CLINICAL STUDY; MALE; MUTANT; PHENOTYPE; PRIORITY JOURNAL; RISK ASSESSMENT; SLEDAI; SYSTOLIC BLOOD PRESSURE; ADOLESCENT; CASE CONTROL STUDY; CLASSIFICATION; COMPLICATION; GENE EXPRESSION REGULATION; GENETIC POLYMORPHISM; GENETIC PREDISPOSITION; GENETICS; INDIA; INTRON; MIDDLE AGED; RISK FACTOR; YOUNG ADULT;

ADOLESCENT; ADULT; ALLELES; AUTOANTIBODIES; CASE-CONTROL STUDIES; FEMALE; GENETIC PREDISPOSITION TO DISEASE; HUMANS; HYPERTENSION; INDIA; INTRONS; LUPUS NEPHRITIS; MALE; MIDDLE AGED; MUTAGENESIS, INSERTIONAL; PEPTIDYL-DIPEPTIDASE A; POLYMORPHISM, GENETIC; RISK FACTORS; YOUNG ADULT;

EID: 84940440017     PISSN: 07703198     EISSN: 14349949     Source Type: Journal    
DOI: 10.1007/s10067-015-2954-6     Document Type: Article

References (24)

1. Wakeland EK, Liu K, Graham RR, Behrens TW (2001) Delineating the genetic basis of SLE. Immunity 15:397–408
2. Canetta PA, Bomback AS, Radhakrishnan J (2011) Treating lupus in the kidney: where are we now, and where are we going? Discov Med 12:341–349
3. Ramu P, Umamaheswaran G, Shewade DG, Swaminathan RP, Dutta TK, Balachander J, Adithan C (2011) Candidate gene polymorphisms of renin angiotensin system and essential hypertension in south Indian Tamilian population. Int J Hum Genet 11:31–40
4. Cambien F, Alhenc-Gelas F, Herbeth B, Andre JL, Rakotovao R, Gonzales MF, Allegrini J, Bloch C (1988) Familial resemblance of plasma angiotensin-converting enzyme level: the Nancy Study. Am J Hum Genet 43:774–780
5. Rigat B, Hubert C, Alhenc-Gelas F, Cambien F, Corvol P, Soubrier F (1990) An insertion/deletion polymorphism in the angiotensin I-converting enzyme gene accounting for half the variance of serum enzyme levels. J Clin Invest 86:1343–1346
6. Tabatabaei FAS, Oostra BA, Isaacs AM, Van Duijn CM, Witteman JCM (2006) ACE polymorphisms. Circ Res 98:1123–1133
7. Ryan MJ (2009) The pathophysiology of hypertension in systemic lupus erythematosus. Am J Physiol Regul Integr Comp Physiol 296:R1258–R1267
8. Hochberg MC (1997) Updating the American College of Rheumatology revised criteria for the classification of systemic lupus erythematosus. Arthritis Rheum 40:1725
9. Bombardier C, Gladman DD, Urowitz MB, Caron D, Chang CH (1992) Derivation of the SLEDAI. A disease activity index for lupus patients. The Committee on Prognosis Studies in SLE. Arthritis Rheum 35:630–640
10. Markowitz GS, D’Agati VD (2007) The ISN/RPS 2003 classification of lupus nephritis: an assessment at 3 years. Kidney Int 71:491–495
11. Chobanian AV, George LB, Henry RB et al (2003) The Seventh Report of the Joint National Committee on report prevention, detection, evaluation, and treatment of high blood pressure: the JNC 7 report. JAMA 289:2560–2571
12. Miller SA, Dykes DD, Polesky HF (1988) Simple salting out procedure for extracting DNA from human nucleated cells. Nuc Acids Res 16:1215
13. Patel M, Clarke AM, Bruce IN, Symmons DP (2006) The prevalence and incidence of biopsy-proven lupus nephritis in the UK: evidence of an ethnic gradient. Arthritis Rheum 54:2963–2969
14. Tassiulas IO, Aksentijevich I, Salmon JE, Kim Y, Yarboro CH, Vaughan EM et al (1998) Angiotensin I converting enzyme gene polymorphisms in systemic lupus erythematosus: decreased prevalence of DD genotype in African American patients. Clin Nephrol 50:8–13
15. Malaviya AN, Chandrasekaran AN, Kumar A, Shamar PN (1997) Systemic lupus erythematosus in India. Lupus 6:690–700
16. Remuzzi G, Perico N, Macia M, And Ruggenenti P. The role of renin-angiotensin-aldosterone system in the progression of chronic kidney disease. Kidney Int 2005;68 9 (Suppl 99): pp. S57–S6
17. Sprovieri SR, Sens YA (2005) Polymorphisms of the renin-angiotensin system genes in Brazilian patients with lupus nephropathy. Lupus 14:356–362
18. Molad Y, Gal E, Magal N, Sulkes J et al (2000) Renal outcome and vascular morbidity in systemic lupus erythematosus (SLE): lack of association with the angiotensin-converting enzyme gene polymorphism. Semin Arthritis Rheum 30:132–137
19. Prkacin I, Novak B, Sertić J, Mrzljak A (2001) Angiotensin-converting enzyme gene polymorphism in patients with systemic lupus. Acta Med Croatica 55:73–76
20. Akai Y, Sato H, Iwano M, Kurumatani N, Kurioka H, Kubo A et al (1999) Association of an insertion polymorphism of angiotensin-converting enzyme gene with the activity of lupus nephritis. Clin Nephrol 51:141–146
21. Zhou TB, Liu YG, Lin N, Qin YH, Huang K, Shao MB, Peng DD (2012) Relationship between angiotensin-converting enzyme insertion/deletion gene polymorphism and systemic lupus erythematosus/lupus nephritis: a systematic review and metaanalysis. J Rheumatol 39:686–693
22. Topete-Reyes JF, SotoVargas J, Morán Moguel MC, Dávalos-Rodríguez (2013) Insertion/deletion polymorphism of the angiotensin-converting enzyme gene in lupus nephritis among Mexicans. Immunopharmacol Immunotoxicol 35:174–180
23. Pullmann RJ, Lukac J, Skerenova M, Rovensky J, Hybenova J, Melus V et al (1999) Association between systemic lupus erythematosus and insertion/deletion polymorphism of the angiotensin converting enzyme (ACE) gene. Clin Exp Rheumatol 17:593–596
24. Uhm WS, Lee HS, Chung YH, Kim TH et al (2002) Angiotensin-converting enzyme gene polymorphism and vascular manifestations in Korean patients with SLE. Lupus 11:227–233