The female urinary microbiome in urgency urinary incontinence

American Journal of Obstetrics and Gynecology

Volumn 213, Issue 3, 2015, Pages 347.e1-347.e11

  Pearce, Meghan M ^a   Zilliox, Michael J ^a   Rosenfeld, Amy B ^b   Thomas White, Krystal J ^a   Richter, Holly E ^c   Nager, Charles W ^d   Visco, Anthony G ^e   Nygaard, Ingrid E ^g   Barber, Matthew D ^h   Schaffer, Joseph ⁱ   Moalli, Pamela ^j   Sung, Vivian W ^l   Smith, Ariana L ^k   Rogers, Rebecca ^m   Nolen, Tracy L ^f   Wallace, Dennis ^f   Meikle, Susan F ⁿ   Gai, Xiaowu ^a   Wolfe, Alan J ^a   Brubaker, Linda ^a  

^a LOYOLA UNIVERSITY CHICAGO   (United States)

^b Columbia University ^*  (United States)

^c UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

^d UNIVERSITY OF CALIFORNIA SAN DIEGO HEALTH SYSTEM   (United States)

^e DUKE UNIVERSITY MEDICAL CENTER   (United States)

^f RTI INTERNATIONAL   (United States)

^g UNIVERSITY OF UTAH SCHOOL OF MEDICINE   (United States)

^h LERNER RESEARCH INSTITUTE   (United States)

ⁱ UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^j UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^k UNIVERSITY OF PENNSYLVANIA   (United States)

^l BROWN UNIVERSITY   (United States)

^m UNIVERSITY OF NEW MEXICO SCHOOL OF MEDICINE   (United States)

ⁿ EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH AND HUMAN DEVELOPMENT   (United States)

more..

Author keywords

bacteria; microbiome; microbiota; urgency urinary incontinence; urinary tract infection

Indexed keywords

ADULT; AEROCOCCUS; AGE; AGED; ARTICLE; BIFIDOBACTERIUM; BODY MASS; DNA SEQUENCE; ENTEROBACTERIACEAE; FEMALE; GARDNERELLA; HUMAN; LACTOBACILLUS; MAJOR CLINICAL STUDY; MICROFLORA; PREVOTELLA; PRIORITY JOURNAL; STAPHYLOCOCCUS; TREATMENT OUTCOME; URINALYSIS; URINARY TRACT INFECTION; URINARY URGENCY; URINE INCONTINENCE; BACTERIURIA; BACTEROIDACEAE INFECTIONS; GENETICS; GRAM-POSITIVE BACTERIAL INFECTIONS; ISOLATION AND PURIFICATION; MICROBIOLOGY; MIDDLE AGED; OBESITY; QUALITY OF LIFE; URINARY INCONTINENCE, URGE; URINARY TRACT; URINARY TRACT INFECTIONS;

ACETYLCHOLINE RELEASE INHIBITOR; BOTULINUM TOXIN A; CHOLINERGIC RECEPTOR BLOCKING AGENT; RNA 16S;

ACETYLCHOLINE RELEASE INHIBITORS; ADULT; AGE FACTORS; AGED; BACTERIURIA; BACTEROIDACEAE INFECTIONS; BODY MASS INDEX; BOTULINUM TOXINS, TYPE A; CHOLINERGIC ANTAGONISTS; FEMALE; GARDNERELLA; GRAM-POSITIVE BACTERIAL INFECTIONS; HUMANS; LACTOBACILLUS; MICROBIOTA; MIDDLE AGED; OBESITY; PREVOTELLA; QUALITY OF LIFE; RNA, RIBOSOMAL, 16S; TREATMENT OUTCOME; URINARY INCONTINENCE, URGE; URINARY TRACT; URINARY TRACT INFECTIONS;

EID: 84940421485     PISSN: 00029378     EISSN: 10976868     Source Type: Journal    
DOI: 10.1016/j.ajog.2015.07.009     Document Type: Article

References (18)

1. A.G. Visco, L. Brubaker, H.E. Richter, and et al. Anticholinergic therapy vs onabotulinumtoxinA for urgency urinary incontinence N Engl J Med 367 2012 1803 1813
2. L. Brubaker, and A. Wolfe The new world of the urinary microbiome in women Am J Obset Gynecol 2015 [Epub ahead of print]
3. L. Brubaker, C.W. Nager, H.E. Richter, and et al. Urinary bacteria in adult women with urgency urinary incontinence Int Urogynecol J 25 2014 1179 1184
4. A.J. Wolfe, E. Toh, N. Shibata, and et al. Evidence of uncultivated bacteria in the adult female bladder J Clin Microbiol 50 2012 1376 1383
5. A.G. Visco, L. Brubaker, H.E. Richter, and et al. Anticholinergic versus botulinum toxin A comparison trial for the treatment of bothersome urge urinary incontinence: ABC trial Contemp Clin Trials 33 2012 184 196
6. E.E. Hilt, K. McKinley, M.M. Pearce, and et al. Urine is not sterile: Use of enhanced urine culture techniques to detect resident bacterial flora in the adult female bladder J Clin Microbiol 52 2014 871 876
7. M.M. Pearce, E.E. Hilt, A.B. Rosenfeld, and et al. The female urinary microbiome: a comparison of women with and without urgency urinary incontinence MBio 5 2014 e01283-14
8. S. Yuan, D. Cohen, J. Ravel, Z. Abdo, and L. Forney Evaluation of methods for the extraction and purification of DNA from the human microbiome PLoS One 3 2012 e33865
9. P.D. Schloss, S.L. Westcott, T. Ryabin, and et al. Introducing mothur: Open-source, platform-independent, community-supported software for describing and comparing microbial communities Appl Environ Microbiol 75 2009 7537 7541
10. C. Quast, E. Pruesse, P. Yilmaz, and et al. The SILVA ribosomal RNA gene database project: Improved data processing and web-based tools Nucleic Acids Res 41 2013 D590 D596
11. R.C. Edgar, B.J. Haas, J.C. Clemente, C. Quince, and R. Knight UCHIME improves sensitivity and speed of chimera detection Bioinformatics 27 2011 2194 2200
12. D. Arndt, J. Xia, Y. Liu, and et al. METAGENassist: a comprehensive web server for comparative metagenomics Nucleic Acids Res 40 2012 W88 W95
13. D.E. Fouts, R. Pieper, S. Szpakowski, and et al. Integrated next-generation sequencing of 16S rDNA and metaproteomics differentiate the healthy urine microbiome from asymptomatic bacteriuria in neuropathic bladder associated with spinal cord injury J Transl Med 10 2012 174
14. R. Khasriya, S. Sathiananthamoorthy, S. Ismail, and et al. Spectrum of bacterial colonization associated with urothelial cells from patients with chronic lower urinary tract symptoms J Clin Microbiol 51 2013 2054 2062
15. V. Nienhouse, X. Gao, Q. Dong, and et al. Interplay between bladder microbiota and urinary antimicrobial peptides: mechanisms for human urinary tract infection risk and symptom severity PLoS One 9 2014 e114185
16. Q. Dong, D.E. Nelson, E. Toh, and et al. The microbial communities in male first catch urine are highly similar to those in paired urethral swab specimens PLoS One 6 2011 e19709
17. D.E. Nelson, Q. Dong, B. Van Der Pol, and et al. Bacterial communities of the coronal sulcus and distal urethra of adolescent males PLoS One 7 2012 e36298
18. D.E. Nelson, B. Van Der Pol, Q. Dong, and et al. Characteristic male urine microbiomes associate with asymptomatic sexually transmitted infection PLoS One 5 2010 e1411 e1416