A common sugar-nucleotide-mediated mechanism of inhibition of (glycosamino)glycan biosynthesis, as evidenced by 6F-GalNAc (Ac3)

FASEB Journal

Volumn 29, Issue 7, 2015, Pages 2993-3002

  Van Wijk, Xander M ^a   Lawrence, Roger ^c   Thijssen, Victor L ^d   Van Den Broek, Sebastiaan A ^b   Troost, Ran ^a   Van Scherpenzeel, Monique ^b   Naidu, Natasha ^d   Oosterhof, Arie ^a   Griffioen, Arjan W ^e   Lefeber, Dirk J ^b   Van Delft, Floris L ^b   Van Kuppevelt, Toin H ^a  

^a RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

^b RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d UNIVERSITY OF CALIFORNIA   (United States)

^e VU UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

Angiogenesis; Glycobiology; Growth factor signaling; Sugar analog

Indexed keywords

CHONDROITIN; DERMATAN SULFATE; GLYCAN DERIVATIVE; GLYCOSAMINOGLYCAN; GROWTH FACTOR; HEPARAN SULFATE; LECTIN; N ACETYLGLUCOSAMINE; PEANUT AGGLUTININ; POLYSACCHARIDE; SUGAR NUCLEOTIDE; URIDINE DIPHOSPHATE; FIBROBLAST GROWTH FACTOR 2; N ACETYLGALACTOSAMINE; URIDINE DIPHOSPHATE N ACETYLGALACTOSAMINE; URIDINE DIPHOSPHATE N ACETYLGLUCOSAMINE; VASCULOTROPIN A; VEGFA PROTEIN, HUMAN;

ANGIOGENESIS; ARTICLE; BIOSYNTHESIS; DATURA STRAMONIUM; DEPLETION; FEMALE; HUMAN; HUMAN CELL; IN VIVO STUDY; NONHUMAN; OVARY CARCINOMA; PRIORITY JOURNAL; PROTEIN MODIFICATION; SIGNAL TRANSDUCTION; ANALOGS AND DERIVATIVES; ANIMAL; ANTAGONISTS AND INHIBITORS; CELL LINE; CHEMISTRY; CHICK EMBRYO; DRUG EFFECTS; HELA CELL LINE; METABOLISM; STRUCTURE ACTIVITY RELATION; UMBILICAL VEIN ENDOTHELIAL CELL;

ARACHIS HYPOGAEA; DATURA STRAMONIUM;

ACETYLGALACTOSAMINE; ANIMALS; CELL LINE; CHICK EMBRYO; FIBROBLAST GROWTH FACTOR 2; GLYCOSAMINOGLYCANS; HELA CELLS; HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS; HUMANS; NEOVASCULARIZATION, PHYSIOLOGIC; POLYSACCHARIDES; SIGNAL TRANSDUCTION; STRUCTURE-ACTIVITY RELATIONSHIP; URIDINE DIPHOSPHATE N-ACETYLGALACTOSAMINE; URIDINE DIPHOSPHATE N-ACETYLGLUCOSAMINE; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 84940398857     PISSN: 08926638     EISSN: 15306860     Source Type: Journal    
DOI: 10.1096/fj.14-264226     Document Type: Article

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