Cytochrome P450 1B1 and primary congenital glaucoma

Journal of Ophthalmic and Vision Research

Volumn 10, Issue 1, 2015, Pages 60-67

  Zhao, Yun ^a   Sorenson, Christine M ^a   Sheibani, Nader ^a  

^a UNIVERSITY OF WISCONSIN SCHOOL OF MEDICINE AND PUBLIC HEALTH   (United States)

Author keywords

Anterior Chamber; Cyp1b1; Oxidative Stress; Periostin; Trabecular Meshwork

Indexed keywords

EID: 84940392740     PISSN: 20082010     EISSN: 2008322X     Source Type: Journal    
DOI: 10.4103/2008-322X.156116     Document Type: Article

References (54)

1. Muskhelishvili L, Thompson PA, Kusewitt DF, Wang C, Kadlubar FF. In situ hybridization and immunohistochemical analysis of cytochrome P450 1B1 expression in human normal tissues. J Histochem Cytochem 2001;49:229-236.
2. Nelson DR, Koymans L, Kamataki T, Stegeman JJ, Feyereisen R, Waxman DJ, et al. P450 superfamily: Update on new sequences, gene mapping, accession numbers and nomenclature. Pharmacogenetics 1996;6:1-42.
3. Nebert DW, Russell DW. Clinical importance of the cytochromes P450. Lancet 2002;360:1155-1162.
4. Shimada T, Hayes CL, Yamazaki H, Amin S, Hecht SS, Guengerich FP, et al. Activation of chemically diverse procarcinogens by human cytochrome P-450 1B1. Cancer Res 1996;56:2979-2984.
5. Porter TD, Coon MJ. Cytochrome P-450. Multiplicity of isoforms, substrates, and catalytic and regulatory mechanisms. J Biol Chem 1991;266:13469-13472.
6. Choudhary D, Jansson I, Sarfarazi M, Schenkman JB. Physiological significance and expression of P450s in the developing eye. Drug Metab Rev 2006;38:337-352.
7. Libby RT, Smith RS, Savinova OV, Zabaleta A, Martin JE, Gonzalez FJ, et al. Modification of ocular defects in mouse developmental glaucoma models by tyrosinase. Science 2003;299:1578-1581.
8. Stoilov I, Akarsu AN, Sarfarazi M. Identification of three different truncating mutations in cytochrome P4501B1 (Cyp1b1) as the principal cause of primary congenital glaucoma (Buphthalmos) in families linked to the GLC3A locus on chromosome 2p21. Hum Mol Genet 1997;6:641-647.
9. Tang YM, Wo YY, Stewart J, Hawkins AL, Griffin CA, Sutter TR, et al. Isolation and characterization of the human cytochrome P450 Cyp1b1 gene. J Biol Chem 1996;271:28324-28330.
10. Murray GI, Melvin WT, Greenlee WF, Burke MD. Regulation, function, and tissue-specific expression of cytochrome P450 Cyp1b1. Annu Rev Pharmacol Toxicol 2001;41:297-316.
11. Zhang L, Savas U, Alexander DL, Jefcoate CR. Characterization of the mouse Cyp1b1 gene. Identification of an enhancer region that directs aryl hydrocarbon receptor-mediated constitutive and induced expression. J Biol Chem 1998;273:5174-5183.
12. Stoilov I, Akarsu AN, Alozie I, Child A, Barsoum-Homsy M, Turacli ME, et al. Sequence analysis and homology modeling suggest that primary congenital glaucoma on 2p21 results from mutations disrupting either the hinge region or the conserved core structures of cytochrome P4501B1. Am J Hum Genet 1998;62:573-584.
13. Stoilov I, Rezaie T, Jansson I, Schenkman JB, Sarfarazi M. Expression of cytochrome P4501b1 (Cyp1b1) during early murine development. Mol Vis 2004;10:629-636.
14. Savas U, Bhattacharyya KK, Christou M, Alexander DL, Jefcoate CR. Mouse cytochrome P-450EF, representative of a new 1B subfamily of cytochrome P-450s. Cloning, sequence determination, and tissue expression. J Biol Chem 1994;269:14905-14911.
15. Bhattacharyya KK, Brake PB, Eltom SE, Otto SA, Jefcoate CR. Identification of a rat adrenal cytochrome P450 active in polycyclic hydrocarbon metabolism as rat Cyp1b1. Demonstration of a unique tissue-specific pattern of hormonal and aryl hydrocarbon receptor-linked regulation. J Biol Chem 1995;270:11595-11602.
16. Sutter TR, Tang YM, Hayes CL, Wo YY, Jabs EW, Li X, et al. Complete cDNA sequence of a human dioxin-inducible mRNA identifies a new gene subfamily of cytochrome P450 that maps to chromosome 2. J Biol Chem 1994;269:13092-13099.
17. Vasiliou V, Gonzalez FJ. Role of Cyp1b1 in glaucoma. Annu Rev Pharmacol Toxicol 2008;48:333-358.
18. Choudhary D, Jansson I, Rezaul K, Han DK, Sarfarazi M, Schenkman JB. Cyp1b1 protein in the mouse eye during development: An immunohistochemical study. Drug Metab Dispos 2007;35:987-994.
19. Remé C, d'Epinay SL. Periods of development of the normal human chamber angle. Doc Ophthalmol 1981;51:241-268.
20. Doshi M, Marcus C, Bejjani BA, Edward DP. Immunolocalization of Cyp1b1 in normal, human, fetal and adult eyes. Exp Eye Res 2006;82:24-32.
21. Smith R, John S, Nishina P, Sundberg J. Systematic Evaluation of the Mouse Eye: Anatomy, Pathology and Biomethods. ed. Bocan Raton, FL: CRC Press; 2001.
22. Bejjani BA, Xu L, Armstrong D, Lupski JR, Reneker LW. Expression patterns of cytochrome P4501B1 (Cyp1b1) in FVB/N mouse eyes. Exp Eye Res 2002;75:249-257.
23. Napier HR, Kidson SH. Proliferation and cell shape changes during ciliary body morphogenesis in the mouse. Dev Dyn 2005;233:213-223.
24. Beebe DC. Development of the ciliary body: A brief review. Trans Ophthalmol Soc U K 1986;105 (Pt 2):123-130.
25. Tomarev SI, Wistow G, Raymond V, Dubois S, Malyukova I. Gene expression profile of the human trabecular meshwork: NEIBank sequence tag analysis. Invest Ophthalmol Vis Sci 2003;44:2588-2596.
26. Zhao Y, Wang S, Sorenson CM, Teixeira L, Dubielzig RR, Peters DM, et al. Cyp1b1 mediates periostin regulation of trabecular meshwork development by suppression of oxidative stress. Mol Cell Biol 2013;33:4225-4240.
27. Quigley HA, Broman AT. The number of people with glaucoma worldwide in 2010 and 2020. Br J Ophthalmol 2006;90:262-267.
28. Shields BM, Ritch R, Krupin T. The Glaucomas. Vol. 2. St. Louis: Mosby; 1996.
29. Hoskins HD Jr, Shaffer RN, Hetherington J. Anatomical classification of the developmental glaucomas. Arch Ophthalmol 1984;102:1331-1336.
30. Sarfarazi M, Stoilov I. Molecular genetics of primary congenital glaucoma. Eye (Lond) 2000;14:422-428.
31. Tanwar M, Dada T, Sihota R, Dada R. Mitochondrial DNA analysis in primary congenital glaucoma. Mol Vis 2010;16:518-533.
32. François J. Congenital glaucoma and its inheritance. Ophthalmologica 1980;181:61-73.
33. Gencik A, Gencikova A, Ferák V. Population genetical aspects of primary congenital glaucoma. I. Incidence, prevalence, gene frequency, and age of onset. Hum Genet 1982;61:193-197.
34. Sarfarazi M, Akarsu AN, Hossain A, Turacli ME, Aktan SG, Barsoum-Homsy M, et al. Assignment of a locus (GLC3A) for primary congenital glaucoma (Buphthalmos) to 2p21 and evidence for genetic heterogeneity. Genomics 1995;30:171-177.
35. Akarsu AN, Turacli ME, Aktan SG, Barsoum-Homsy M, Chevrette L, Sayli BS, et al. A second locus (GLC3B) for primary congenital glaucoma (Buphthalmos) maps to the 1p36 region. Hum Mol Genet 1996;5:1199-1203.
36. Hollander DA, Sarfarazi M, Stoilov I, Wood IS, Fredrick DR, Alvarado JA. Genotype and phenotype correlations in congenital glaucoma: Cyp1b1 mutations, goniodysgenesis, and clinical characteristics. Am J Ophthalmol 2006;142:993-1004.
37. Achary MS, Reddy AB, Chakrabarti S, Panicker SG, Mandal AK, Ahmed N, et al. Disease-causing mutations in proteins: Structural analysis of the Cyp1b1 mutations causing primary congenital glaucoma in humans. Biophys J 2006;91:4329-4339.
38. Panicker SG, Mandal AK, Reddy AB, Gothwal VK, Hasnain SE. Correlations of genotype with phenotype in Indian patients with primary congenital glaucoma. Invest Ophthalmol Vis Sci 2004;45:1149-56.
39. Bejjani BA, Stockton DW, Lewis RA, Tomey KF, Dueker DK, Jabak M, et al. Multiple Cyp1b1 mutations and incomplete penetrance in an inbred population segregating primary congenital glaucoma suggest frequent de novo events and a dominant modifier locus. Hum Mol Genet 2000;9:367-374.
40. Mashima Y, Suzuki Y, Sergeev Y, Ohtake Y, Tanino T, Kimura I, et al. Novel cytochrome P4501B1 (Cyp1b1) gene mutations in Japanese patients with primary congenital glaucoma. Invest Ophthalmol Vis Sci 2001;42:2211-2216.
41. Spector A, Garner WH. Hydrogen peroxide and human cataract. Exp Eye Res 1981;33:673-681.
42. Reiss GR, Werness PG, Zollman PE, Brubaker RF. Ascorbic acid levels in the aqueous humor of nocturnal and diurnal mammals. Arch Ophthalmol 1986;104:753-755.
43. Behndig A, Svensson B, Marklund SL, Karlsson K. Superoxide dismutase isoenzymes in the human eye. Invest Ophthalmol Vis Sci 1998;39:471-475.
44. Ferreira SM, Lerner SF, Brunzini R, Evelson PA, Llesuy SF. Oxidative stress markers in aqueous humor of glaucoma patients. Am J Ophthalmol 2004;137:62-69.
45. Beit-Yannai E, Trembovler V, Solomon AS. Decrease in reducing power of aqueous humor originating from glaucomatous rabbits. Eye (Lond) 2007;21:658-664.
46. Alvarado J, Murphy C, Polansky J, Juster R. Age-related changes in trabecular meshwork cellularity. Invest Ophthalmol Vis Sci 1981;21:714-727.
47. Riley MV. Physiologic neutralization mechanisms and the response of the corneal endothelium to hydrogen peroxide. CLAO J 1990;16:S16-S21.
48. Kahn MG, Giblin FJ, Epstein DL. Glutathione in calf trabecular meshwork and its relation to aqueous humor outflow facility. Invest Ophthalmol Vis Sci 1983;24:1283-1287.
49. Norris RA, Damon B, Mironov V, Kasyanov V, Ramamurthi A, Moreno-Rodriguez R, et al. Periostin regulates collagen fibrillogenesis and the biomechanical properties of connective tissues. J Cell Biochem 2007;101:695-711.
50. Tang Y, Scheef EA, Wang S, Sorenson CM, Marcus CB, Jefcoate CR, et al. Cyp1b1 expression promotes the proangiogenic phenotype of endothelium through decreased intracellular oxidative stress and thrombospondin-2 expression. Blood 2009;113:744-754.
51. Palenski TL, Sorenson CM, Sheibani N. Inflammatory cytokine-specific alterations in retinal endothelial cell function. Microvasc Res 2013;89:57-69.
52. Tang Y, Scheef EA, Gurel Z, Sorenson CM, Jefcoate CR, Sheibani N. Cyp1b1 and endothelial nitric oxide synthase combine to sustain proangiogenic functions of endothelial cells under hyperoxic stress. Am J Physiol Cell Physiol 2010;298:C665-C678.
53. Palenski TL, Sorenson CM, Jefcoate CR, Sheibani N. Lack of Cyp1b1 promotes the proliferative and migratory phenotype of perivascular supporting cells. Lab Invest 2013;93:646-662.
54. Palenski TL, Gurel Z, Sorenson CM, Hankenson KD, Sheibani N. Cyp1b1 expression promotes angiogenesis by suppressing NF-?B activity. Am J Physiol Cell Physiol 2013;305:C1170-C1184.