A novel bedside diagnostic test for methanol poisoning using dry chemistry for formate

Scandinavian Journal of Clinical and Laboratory Investigation

Volumn 75, Issue 7, 2015, Pages 610-614

  Hovda, Knut Erik ^a   Gadeholt, Gaut ^a   Evtodienko, Vladimir ^b   Jacobsen, Dag ^a  

^a OSLO UNIVERSITY HOSPITAL   (Norway)

^b Evik Diagnostics   (Canada)

Author keywords

acidosis; bedside testing; diagnosis; formate dehydrogenase; formic acid; Methanol poisoning; point of care technology

Indexed keywords

FORMATE DEHYDROGENASE; FORMAZAN; FORMIC ACID; METHANOL; NICOTINAMIDE ADENINE DINUCLEOTIDE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE; FORMIC ACID DERIVATIVE;

ARTICLE; CONTROLLED STUDY; DIAGNOSTIC TEST; FEASIBILITY STUDY; HUMAN; METABOLIC ACIDOSIS; METHANOL POISONING; PHOTOMETER; PRIORITY JOURNAL; RELIABILITY; SCREENING; BLOOD; BLOOD ANALYSIS; DIAGNOSIS; EVALUATION STUDY; INTOXICATION; POINT OF CARE TESTING; PROCEDURES; SENSITIVITY AND SPECIFICITY;

BLOOD CHEMICAL ANALYSIS; FORMATES; HUMANS; METHANOL; POINT-OF-CARE TESTING; POISONING; SENSITIVITY AND SPECIFICITY;

EID: 84940376889     PISSN: 00365513     EISSN: 15027686     Source Type: Journal    
DOI: 10.3109/00365513.2015.1066847     Document Type: Article

References (17)

1. Jacobsen D, McMartin KE. Methanol and ethylene glycol poisonings. Mechanism of toxicity, clinical course, diagnosis and treatment. Med Toxicol 1986; 1: 309-34.
2. Brent J, McMartin K, Phillips S, Aaron C, Kulig K, Methylpyrazole for Toxic Alcohols Study G. Fomepizole for the treatment of methanol poisoning. N Engl J Med 2001; 344: 424-9.
3. Barceloux D G, Bond G R, Krenzelok E P, Cooper H, Vale JA, American Academy of Clinical Toxicology Ad Hoc Committee on the Treatment Guidelines for Methanol P. American Academy of Clinical Toxicology practice guidelines on the treatment of methanol poisoning. J Toxicol Clin Toxicol 2002; 40: 415-46.
4. Vinet B. An enzymic assay for the specifi c determination of methanol in serum. Clin Chem 1987; 33: 2204-8.
5. Vinet B. E nzymic methanol determination: toxic concentrations of ethanol may give positive values. Clin Chem 1988; 34: 1944.
6. Hovda KE, Urdal P, Jacobsen D. Increased serum formate in the diagnosis of methanol poisoning. J Anal Toxicol 2005; 29: 586-8.
7. Zakharov S, Pelclova D, Urban P, Navratil T, Diblik P, Kuthan P, Hubacek JA, Miovsky M, Klempir J, Vaneckova M, Seidl Z, Pilin A, Fenclova Z, Petrik V, Kotikova K, Nurieva O, Ridzon P, Rulisek J, Komarc M, Hovda KE. Czech mass methanol outbreak 2012: epidemiology, challenges and clinical features. Clin Toxicol (Phila) 2014; 52: 1013-24.
8. Bland J M, Altman D G. Comparing methods of measurement: why plotting difference against standard method is misleading. Lancet 1995; 346: 1085-7.
9. Ahmad K. Methanol-laced moonshine kills 140 in Kenya. Lancet 2000; 356: 1911.
10. Hassanian-Moghaddam H, Nikfarjam A, Mirafzal A, Saberinia A, Nasehi AA, Masoumi Asl H, Memaryan N. Methanol mass poisoning in Iran: role of case fi nding in outbreak management. J Public Health (Oxf) 2015; 37: 354-9.
11. World Health Organization-Methanol poisoning outbreaks. 2014 [cited 24 Feb 2015]. Available from: http://www. who. int/environmental-health-emergencies/poisoning/methanol- information. pdf
12. Hovda KE, Hunderi OH, Tafjord A B, Dunlop O, Rudberg N, Jacobsen D. Methanol outbreak in Norway 2002-2004: epidemiology, clinical features and prognostic signs. J Intern Med 2005; 258: 181-90.
13. Paasma R, Hovda KE, Tikkerberi A, Jacobsen D. Methanol mass poisoning in Estonia: outbreak in 154 patients. Clin Toxicol (Phila) 2007; 45: 152-7.
14. Lapatto-Reiniluoto O, Vuori E, Hoppu K, Ojanpera I. F atal poisonings in Finland during the years 2004-2009. Hum Exp Toxicol 2013; 32: 600-5.
15. Zakharov S, Kurcova I, Navratil T, Salek T, Komarc M, Pelclova D. Is the measurement of serum formate concentration useful in the diagnostics of acute methanol poisoningA prospective study of 38 patients. Basic Clin Pharmacol Toxicol 2015; 116: 445-51.
16. Hovda K E, Hunderi O H, Rudberg N, Froyshov S, Jacobsen D. Anion and osmolalgaps in the diagnosis of methanol poisoning: clinical study in 28 patients. Intensive Care Med 2004; 30: 1842-6.
17. Urdal P. E nzymic assay for oxalate in unprocessed urine, as adapted for a centrifugal analyzer. Clin Chem 1984; 30: 911-3.