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PID: 23410543, This is the first study describing MSIMI is more frequent in clinically stable IHD population and identified women are more prone to MSIMI and married men are best protected from having MSIMI
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Jiang W, Samad Z, Boyle S, Becker RC, Williams R, Kuhn C, et al. Prevalence and clinical characteristics of mental stress-induced myocardial ischemia in patients with coronary heart disease. J Am Coll Cardiol. 2013;61:714–22. This is the first study describing MSIMI is more frequent in clinically stable IHD population and identified women are more prone to MSIMI and married men are best protected from having MSIMI.
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20
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Sex differences in platelet reactivity and cardiovascular and psychological response to mental stress in patients with stable ischemic heart disease: insights from the REMIT study
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PID: 25323254, This is the first study that discussed comprehensively that characteristics of women’s psychological and physiological responses to emotional stress
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Samad Z, Boyle S, Ersboll M, Vora AN, Zhang Y, Becker RC, et al. Sex differences in platelet reactivity and cardiovascular and psychological response to mental stress in patients with stable ischemic heart disease: insights from the REMIT study. J Am Coll Cardiol. 2014;64:1669–78. This is the first study that discussed comprehensively that characteristics of women’s psychological and physiological responses to emotional stress.
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Samad, Z.1
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Sex differences in mental stress-induced myocardial ischemia in young survivors of an acute myocardial infarction
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COI: 1:CAS:528:DC%2BC2cXmtVemsb4%3D, PID: 24608039, This study confirms women are more prone to have MSIMI than men, and first noted such phenomena occurs in younger individuals (age <50 year-old)
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Vaccarino V, Shah AJ, Rooks C. Sex differences in mental stress-induced myocardial ischemia in young survivors of an acute myocardial infarction. Psychosom Med. 2014;76:171–80. This study confirms women are more prone to have MSIMI than men, and first noted such phenomena occurs in younger individuals (age <50 year-old).
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Vaccarino, V.1
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23
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Pepine C. Ischemic heart disease in women. J Am Coll Cardiol. 2006;47:S1–3.
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CONFIRM Investigators. Age- and sex-related differences in all-cause mortality risk based on coronary computed tomography angiography findings results from the International Multicenter CONFIRM (Coronary CT Angiography Evaluation for Clinical Outcomes: an International Multicenter Registry) of 23,854 patients without known coronary artery disease
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Min J, Dunning A, Lin FY, Achenbach S, Al-Mallah M, Budoff MJ, et al; CONFIRM Investigators. Age- and sex-related differences in all-cause mortality risk based on coronary computed tomography angiography findings results from the International Multicenter CONFIRM (Coronary CT Angiography Evaluation for Clinical Outcomes: an International Multicenter Registry) of 23,854 patients without known coronary artery disease. J Am Coll Cardiol. 2011;58:849–60.
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26
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84888127408
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Depressive symptoms and mental stress-induced myocardial ischemia in patients with coronary heart disease
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PID: 24163385, Aiming at replicate previous found associations of depression and MSIMI
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Boyle S, Samad Z, Becker RC, Williams R, Kuhn C, Ortel TL, et al. Depressive symptoms and mental stress-induced myocardial ischemia in patients with coronary heart disease. Psychosom Med. 2013;75:822–31. Aiming at replicate previous found associations of depression and MSIMI.
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Boyle, S.1
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27
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84903148388
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Meta-analysis of mental stress-induced myocardial ischemia and subsequent cardiac events in patients with coronary artery disease
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PID: 24856319, A meta-analysis confirms the association of MSIMI and increased poor CV prognosis
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Wei J, Rooks C, Ramadan R, Shah AJ, Bremner JD, Quyyumi AA, et al. Meta-analysis of mental stress-induced myocardial ischemia and subsequent cardiac events in patients with coronary artery disease. Am J Cardiol. 2014;114:187–92. A meta-analysis confirms the association of MSIMI and increased poor CV prognosis.
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Am J Cardiol
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Wei, J.1
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28
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84937059504
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Confluence of depression and acute psychological stress among patients with stable coronary heart disease: effects on myocardial perfusion
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PID: 25359402, Duplicative findings confirming the association of depression and MSIMI
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Burg M, Meadows J, Shimbo D, Davidson KW, Schwartz JE, Soufer R. Confluence of depression and acute psychological stress among patients with stable coronary heart disease: effects on myocardial perfusion. J Am Heart Assoc. 2014;3:e000898. Duplicative findings confirming the association of depression and MSIMI.
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J Am Heart Assoc
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Burg, M.1
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29
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84961291768
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Association between anger and mental stress-induced myocardial ischemia
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PID: 25497256, This study indicates certain measures of anger may be related to MSIMI
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Pimple P, Shah A, Rooks C, Bremner JD, Nye J, Ibeanu I, et al. Association between anger and mental stress-induced myocardial ischemia. Am Heart J. 2015;169:115–21. This study indicates certain measures of anger may be related to MSIMI.
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Am Heart J
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Pimple, P.1
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30
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Prognosis after change in left ventricular ejection fraction during mental stress testing in patients with stable coronary artery disease
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Babyak M, Blumenthal JA, Hinderliter A, Hoffman B, Waugh RA, Coleman RE, et al. Prognosis after change in left ventricular ejection fraction during mental stress testing in patients with stable coronary artery disease. Am J Cadiol. 2010;105:25–8.
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Coleman, R.E.6
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31
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84904886150
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Depressive symptoms are associated with mental stress-induced myocardial ischemia after acute myocardial infarction
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PID: 25061993, Duplicative findings confirming the association of depression and MSIMI
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Wei J, Pimple P, Shah AJ, Rooks C, Bremner JD, Nye JA, et al. Depressive symptoms are associated with mental stress-induced myocardial ischemia after acute myocardial infarction. PLoS One. 2014;9(7):e102986. doi:10.1371/journal.pone.0102986. eCollection 2014. Duplicative findings confirming the association of depression and MSIMI.
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PLoS One
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Wei, J.1
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83555168239
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Responses of mental stress-induced myocardial ischemia to escitalopram treatment: background, design, and method for the Responses of Mental Stress-Induced Myocardial Ischemia to Escitalopram Treatment trial
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COI: 1:CAS:528:DC%2BC3MXhsVOgs7bI, PID: 22172432
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Jiang W, Velazquez EJ, Samad Z, Kuchibhatla M, Martsberger C, Rogers J, et al. Responses of mental stress-induced myocardial ischemia to escitalopram treatment: background, design, and method for the Responses of Mental Stress-Induced Myocardial Ischemia to Escitalopram Treatment trial. Am Heart J. 2012;163:20–6.
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33
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84898775475
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Impaired resting myocardial annular velocities are independently associated with mental stress-induced ischemia in coronary heart disease
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PID: 24631512, First study using parameters that are more sensitive to conventional ischemic measures demonstrating occurrence of MSIMI
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Ersbøll M, Al Enezi F, Samad Z, Sedberry B, Boyle SH, O'Connor C, et al. Impaired resting myocardial annular velocities are independently associated with mental stress-induced ischemia in coronary heart disease. JACC Cardiovasc Imaging. 2014;7:351–61. First study using parameters that are more sensitive to conventional ischemic measures demonstrating occurrence of MSIMI.
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JACC Cardiovasc Imaging
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Ersbøll, M.1
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34
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19944432235
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Comparison of mental stress-induced myocardial ischemia in coronary artery disease patients with versus without left ventricular dysfunction
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PID: 15670538
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Akinboboye O, Krantz DS, Kop WJ, Schwartz SD, Levine J, Del Negro A, et al. Comparison of mental stress-induced myocardial ischemia in coronary artery disease patients with versus without left ventricular dysfunction. Am J Cardiol. 2005;95:322–6.
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34249751469
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Mental stress-induced myocardial ischemia in coronary artery disease patients with left ventricular dysfunction
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PID: 17556164
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Hassan M, York KM, Li H, Li Q, Sheps DS. Mental stress-induced myocardial ischemia in coronary artery disease patients with left ventricular dysfunction. J Nucl Cardiol. 2007;14:308–13.
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Hassan, M.1
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36
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84879748718
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A novel paradigm for heart failure with preserved ejection fraction: comorbidities drive myocardial dysfunction and remodeling through coronary microvascular endothelial inflammation
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PID: 23684677, Mechanistic study examining the microvascular endothelial inflammation and ejection fraction reserved heart failure
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Paulus W, Tschöpe C. A novel paradigm for heart failure with preserved ejection fraction: comorbidities drive myocardial dysfunction and remodeling through coronary microvascular endothelial inflammation. J Am Coll Cardiol. 2013;62:263–71. Mechanistic study examining the microvascular endothelial inflammation and ejection fraction reserved heart failure.
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Paulus, W.1
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Jiang W, Qi L, Martsberger CM, Samad Z, Rogers J, Krishnan R, Williams R, O’Connor CM, Velazquez EJ. Relationship of Resting Diastolic Function and Stress Induced Left Ventricular Dysfunction in Patients with Stable Coronary Heart Disease. 69th APS Annual Meeting 2011;A–74:310
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Jiang W, Qi L, Martsberger CM, Samad Z, Rogers J, Krishnan R, Williams R, O’Connor CM, Velazquez EJ. Relationship of Resting Diastolic Function and Stress Induced Left Ventricular Dysfunction in Patients with Stable Coronary Heart Disease. 69th APS Annual Meeting 2011;A–74:310.
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38
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84891709412
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Myocardial ischemia during mental stress: role of coronary artery disease burden and vasomotion
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PID: 24145741, A study using a very conveniently applied tool to assess the peripheral vascular resistance in relationship of MSIMI and physical stress-induced myocardial ischemia
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Ramadan R, Sheps D, Esteves F, Maziar Zafari A, Bremner JD, Vaccarino V, et al. Myocardial ischemia during mental stress: role of coronary artery disease burden and vasomotion. J Am Heart Assoc. 2013;2:e000321. A study using a very conveniently applied tool to assess the peripheral vascular resistance in relationship of MSIMI and physical stress-induced myocardial ischemia.
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J Am Heart Assoc
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Ramadan, R.1
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Vaccarino, V.6
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39
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84927573656
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Platelet aggregation and mental stress induced myocardial ischemia: results from the Responses of Myocardial Ischemia to Escitalopram Treatment (REMIT) study
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PID: 25819856, This study not only demonstrates the significant change of platelet aggregation under mental stress in patients with MSIMI, but it also indicates that using mental stress testing is a necessary method to investigate certain dynamic changes in the cardiovascular system
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Jiang W, Boyle SH, Ortel TL, Samad Z, Velazquez EJ, Harrison RW, et al. Platelet aggregation and mental stress induced myocardial ischemia: results from the Responses of Myocardial Ischemia to Escitalopram Treatment (REMIT) study. Am Heart J. 2015;169:496–507. This study not only demonstrates the significant change of platelet aggregation under mental stress in patients with MSIMI, but it also indicates that using mental stress testing is a necessary method to investigate certain dynamic changes in the cardiovascular system.
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(2015)
Am Heart J
, vol.169
, pp. 496-507
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Jiang, W.1
Boyle, S.H.2
Ortel, T.L.3
Samad, Z.4
Velazquez, E.J.5
Harrison, R.W.6
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40
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84865474767
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Metabolomic profiling for the identification of novel biomarkers and mechanisms related to common cardiovascular diseases: form and function
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PID: 22927473
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Shah S, Kraus WE, Newgard CB. Metabolomic profiling for the identification of novel biomarkers and mechanisms related to common cardiovascular diseases: form and function. Circulation. 2012;126:1110–20.
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Circulation
, vol.126
, pp. 1110-1120
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Shah, S.1
Kraus, W.E.2
Newgard, C.B.3
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41
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84929470424
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Metabolomics analysis reveals insights into biochemical mechanisms of mental stress-induced left ventricular dysfunction
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COI: 1:CAS:528:DC%2BC2cXhsFSju77E, PID: 25983674, While this study has small sample size, it is novel as it demonstrates the applicability of metabolomics technology is practicable in identifying alterations of metabolites separating mental stress caused from resting and having mental stress-induced left ventricular dysfunction from normal responses of left ventricle
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Boyle S, Matson WR, Velazquez EJ, Samad Z, Williams Jr RB, Sharma S, et al. Metabolomics analysis reveals insights into biochemical mechanisms of mental stress-induced left ventricular dysfunction. Metabolomics. 2015;11:571–82. While this study has small sample size, it is novel as it demonstrates the applicability of metabolomics technology is practicable in identifying alterations of metabolites separating mental stress caused from resting and having mental stress-induced left ventricular dysfunction from normal responses of left ventricle.
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(2015)
Metabolomics
, vol.11
, pp. 571-582
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Boyle, S.1
Matson, W.R.2
Velazquez, E.J.3
Samad, Z.4
Williams, R.B.5
Sharma, S.6
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42
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84877968316
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Effect of escitalopram on mental stress-induced myocardial ischemia: results of the REMIT trial
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COI: 1:CAS:528:DC%2BC3sXhtVGmtLjN, PID: 23695483, This is the first study examining and demonstrating that SSRI improves MSIMI
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Jiang W, Velazquez EJ, Kuchibhatla M, Samad Z, Boyle SH, Kuhn C, et al. Effect of escitalopram on mental stress-induced myocardial ischemia: results of the REMIT trial. JAMA. 2013;309:2139–49. This is the first study examining and demonstrating that SSRI improves MSIMI.
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(2013)
JAMA
, vol.309
, pp. 2139-2149
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Jiang, W.1
Velazquez, E.J.2
Kuchibhatla, M.3
Samad, Z.4
Boyle, S.H.5
Kuhn, C.6
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43
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20144389732
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Effects of exercise and stress management training on markers of cardiovascular risk in patients with ischemic heart disease: a randomized controlled trial
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COI: 1:CAS:528:DC%2BD2MXjtV2qs7Y%3D, PID: 15811982
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Blumenthal J, Sherwood A, Babyak MA. Effects of exercise and stress management training on markers of cardiovascular risk in patients with ischemic heart disease: a randomized controlled trial. JAMA. 2005;293:1626–34.
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JAMA
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Blumenthal, J.1
Sherwood, A.2
Babyak, M.A.3
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44
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84865798754
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Obstructive coronary atherosclerosis and ischemic heart disease: an elusive link
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PID: 22954239
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Marzilli M, Merz CN, Boden WE, Bonow RO, Capozza PG, Chilian WM, et al. Obstructive coronary atherosclerosis and ischemic heart disease: an elusive link. J Am Coll Cardiol. 2012;60:951–6.
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J Am Coll Cardiol
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Marzilli, M.1
Merz, C.N.2
Boden, W.E.3
Bonow, R.O.4
Capozza, P.G.5
Chilian, W.M.6
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45
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0036675722
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Development of indole-3-propionic acid (OXIGON) for Alzheimer’s disease
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COI: 1:CAS:528:DC%2BD38XmvFGjsrw%3D, PID: 12212784
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Bendheim P, Poeggeler B, Neria E, Ziv V, Pappolla MA, Chain DG. Development of indole-3-propionic acid (OXIGON) for Alzheimer’s disease. J Mol Neurosci. 2002;19:213–7.
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J Mol Neurosci
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, pp. 213-217
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Bendheim, P.1
Poeggeler, B.2
Neria, E.3
Ziv, V.4
Pappolla, M.A.5
Chain, D.G.6
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46
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77951949967
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Metabolomic differences in heart failure patients with and without major depression
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PID: 20101071
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Steffens D, Jiang W, Krishnan KR, Karoly ED, Mitchell MW, O'Connor CM, et al. Metabolomic differences in heart failure patients with and without major depression. J Geriatr Psychiatry Neurol. 2010;23:138–46.
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J Geriatr Psychiatry Neurol
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, pp. 138-146
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Steffens, D.1
Jiang, W.2
Krishnan, K.R.3
Karoly, E.D.4
Mitchell, M.W.5
O'Connor, C.M.6
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47
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0034881130
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Relationship of depression to increased risk of mortality and rehospitalization in patients with congestive heart failure
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COI: 1:STN:280:DC%2BD3MvotFKisA%3D%3D, PID: 11493126
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Jiang W, Alexander J, Christopher E, Kuchibhatla M, Gaulden LH, Cuffe MS, et al. Relationship of depression to increased risk of mortality and rehospitalization in patients with congestive heart failure. Arch Intern Med. 2001;161:1849–56.
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Arch Intern Med
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Jiang, W.1
Alexander, J.2
Christopher, E.3
Kuchibhatla, M.4
Gaulden, L.H.5
Cuffe, M.S.6
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48
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84868033558
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Association of depression and survival in patients with chronic heart failure over 12 Years
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PID: 22281436
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Adams J, Kuchibhatla M, Christopher EJ, Alexander JD, Clary GL, Cuffe MS, et al. Association of depression and survival in patients with chronic heart failure over 12 Years. Psychosomatics. 2012;53:339–46.
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Psychosomatics
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, pp. 339-346
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Adams, J.1
Kuchibhatla, M.2
Christopher, E.J.3
Alexander, J.D.4
Clary, G.L.5
Cuffe, M.S.6
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49
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76749130118
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5-hydroxytryptamine receptor stimulation of mitochondrial biogenesis
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COI: 1:CAS:528:DC%2BC3cXltVCktL8%3D, PID: 19875674
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Rasbach K, Funk JA, Jayavelu T, Green PT, Schnellmann RG. 5-hydroxytryptamine receptor stimulation of mitochondrial biogenesis. J Pharmacol Exp Ther. 2010;332:632–9.
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J Pharmacol Exp Ther
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, pp. 632-639
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Rasbach, K.1
Funk, J.A.2
Jayavelu, T.3
Green, P.T.4
Schnellmann, R.G.5
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50
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0038078914
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Overexpression of the serotonin 5-HT2B receptor in heart leads to abnormal mitochondrial function and cardiac hypertrophy
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COI: 1:CAS:528:DC%2BD3sXkslKgt7w%3D, PID: 12810613
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Nebigil C, Jaffré F, Messaddeq N, Hickel P, Monassier L, Launay JM, et al. Overexpression of the serotonin 5-HT2B receptor in heart leads to abnormal mitochondrial function and cardiac hypertrophy. Circulation. 2003;107:3223–9.
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Circulation
, vol.107
, pp. 3223-3229
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Nebigil, C.1
Jaffré, F.2
Messaddeq, N.3
Hickel, P.4
Monassier, L.5
Launay, J.M.6
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51
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62549154977
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Dynamic regulation of mitochondrial function by glucocorticoids
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COI: 1:CAS:528:DC%2BD1MXivFGktbo%3D, PID: 19202080
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Du J, Wang Y, Hunter R, Wei Y, Blumenthal R, Falke C, et al. Dynamic regulation of mitochondrial function by glucocorticoids. Proc Natl Acad Sci U S A. 2009;106:3543–8.
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Proc Natl Acad Sci U S A
, vol.106
, pp. 3543-3548
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Du, J.1
Wang, Y.2
Hunter, R.3
Wei, Y.4
Blumenthal, R.5
Falke, C.6
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52
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34247598856
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Duchen MR Endothelial mitochondria: contributing to vascular function and disease
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COI: 1:CAS:528:DC%2BD2sXktlOhsrY%3D, PID: 17463328
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Davidson S. Duchen MR Endothelial mitochondria: contributing to vascular function and disease. Circ Res. 2007;100:1128–41.
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Circ Res
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, pp. 1128-1141
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Davidson, S.1
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53
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84898419484
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Current perspective on mental stress-induced myocardial ischemia
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COI: 1:CAS:528:DC%2BC2cXmtVemsLc%3D, PID: 24677165, A good expert opinion paper discussing MSIMI
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Krantz D, Burg MM. Current perspective on mental stress-induced myocardial ischemia. Psychosom Med. 2014;76:168–70. A good expert opinion paper discussing MSIMI.
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Psychosom Med
, vol.76
, pp. 168-170
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Krantz, D.1
Burg, M.M.2
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54
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84873681470
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Mitochondria in vascular health and disease
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COI: 1:CAS:528:DC%2BC3sXjvFOnsbs%3D, PID: 23157555, A good review paper discussing the role of mitochondria in the health and diseases related to vascular functions
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Dromparis P, Michelakis ED. Mitochondria in vascular health and disease. Annu Rev Physiol. 2013;75:95–126. A good review paper discussing the role of mitochondria in the health and diseases related to vascular functions.
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Annu Rev Physiol
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, pp. 95-126
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Dromparis, P.1
Michelakis, E.D.2
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55
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84876347779
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Mitochondria and endothelial function
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COI: 1:CAS:528:DC%2BC3sXlslansL4%3D, PID: 23580773, A good review article discussing the role of mitochondria in endothelial function and dysfunction in relationship to many diseases
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Kluge M, Fetterman JL, Vita JA. Mitochondria and endothelial function. Circ Res. 2013;112:1171–88. A good review article discussing the role of mitochondria in endothelial function and dysfunction in relationship to many diseases.
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(2013)
Circ Res
, vol.112
, pp. 1171-1188
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Kluge, M.1
Fetterman, J.L.2
Vita, J.A.3
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56
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84904321037
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Mitochondria, endothelial cell function, and vascular diseases
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PID: 24834056, A thorough review article discussing the role of mitochondria in endothelial function and dysfunction in relationship to many diseases
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Tang X, Luo YX, Chen HZ, Liu DP. Mitochondria, endothelial cell function, and vascular diseases. Front Physiol. 2014;5:175. A thorough review article discussing the role of mitochondria in endothelial function and dysfunction in relationship to many diseases.
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(2014)
Front Physiol
, vol.5
, pp. 175
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Tang, X.1
Luo, Y.X.2
Chen, H.Z.3
Liu, D.P.4
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57
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77956586695
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Mitochondria in heart failure
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COI: 1:CAS:528:DC%2BC3cXhtFGhtr%2FN
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Rosca M, Hoppel CL. Mitochondria in heart failure. Cardiovas Res. 2010;88:40.
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Cardiovas Res
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, pp. 40
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Rosca, M.1
Hoppel, C.L.2
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58
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Mitochondria and heart disease
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Griffiths E. Mitochondria and heart disease. Adv Exp Med Biol. 2012;942
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Adv Exp Med Biol
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Griffiths, E.1
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59
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84867738060
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Mitochondria as a drug target in ischemic heart disease and cardiomyopathy
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COI: 1:CAS:528:DC%2BC38XhsV2isrbM, PID: 23065345
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Walters A, Porter GA, Brookes PS. Mitochondria as a drug target in ischemic heart disease and cardiomyopathy. Circ Res. 2012;111:1222–36.
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Circ Res
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Walters, A.1
Porter, G.A.2
Brookes, P.S.3
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60
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84871762432
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Mitochondrial dynamics in heart disease
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COI: 1:CAS:528:DC%2BC38Xlt1KksLk%3D, A thorough review article discussing the role of mitochondrial dynamics in heart disease
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Dorn G. Mitochondrial dynamics in heart disease. Biochimica et Biophysica Acta Mol Cell Res. 2013;1833:233–41. A thorough review article discussing the role of mitochondrial dynamics in heart disease.
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(2013)
Biochimica et Biophysica Acta Mol Cell Res
, vol.1833
, pp. 233-241
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Dorn, G.1
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