Removal of SOST or blocking its product sclerostin rescues defects in the periodontitis mouse model

FASEB Journal

Volumn 29, Issue 7, 2015, Pages 2702-2711

  Ren, Yinshi ^a   Han, Xianglong ^a,b   Ho, Sunita P ^c   Harris, Stephen E ^d   Cao, Zhengguo ^e   Economides, Aris N ^f   Qin, Chunlin ^a   Ke, Huazhu ^g   Liu, Min ^g   Feng, Jian Q ^a  

^a BAYLOR COLLEGE OF DENTISTRY   (United States)

^b SICHUAN UNIVERSITY   (China)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT SAN ANTONIO   (United States)

^e WUHAN UNIVERSITY   (China)

^f REGENERON PHARMACEUTICALS INC   (United States)

^g AMGEN INC   (United States)

Author keywords

Alveolar bone; PDL; Periostin

Indexed keywords

SCLEROSTIN; WNT PROTEIN; CELL ADHESION MOLECULE; COLLAGEN; GLYCOPROTEIN; MONOCLONAL ANTIBODY; POSTN PROTEIN, MOUSE; SOST PROTEIN, MOUSE;

ALVEOLAR BONE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL COUNT; CONTROLLED STUDY; DENDRITE; GENE DELETION; MARKER GENE; MOUSE; NONHUMAN; OSTEOCYTE; PERIODONTAL LIGAMENT; PERIODONTITIS; PERIOSTEUM; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; SOST GENE; STEM CELL; ALVEOLAR BONE LOSS; ANIMAL; ANTAGONISTS AND INHIBITORS; C57BL MOUSE; CELL LINEAGE; DEFICIENCY; DISEASE MODEL; GENETICS; KNOCKOUT MOUSE; METABOLISM; PATHOLOGY; PATHOPHYSIOLOGY; PHENOTYPE; WNT SIGNALING PATHWAY;

ANIMALIA; MURINAE; MUS;

ALVEOLAR BONE LOSS; ANIMALS; ANTIBODIES, MONOCLONAL; CELL ADHESION MOLECULES; CELL LINEAGE; COLLAGEN; DISEASE MODELS, ANIMAL; GLYCOPROTEINS; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; OSTEOCYTES; PERIODONTAL LIGAMENT; PERIODONTITIS; PHENOTYPE; WNT SIGNALING PATHWAY;

EID: 84940112283     PISSN: 08926638     EISSN: 15306860     Source Type: Journal    
DOI: 10.1096/fj.14-265496     Document Type: Article

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