A Randomized Controlled Trial to Reduce Falls in People with Parkinson's Disease

Neurorehabilitation and Neural Repair

Volumn 29, Issue 8, 2015, Pages 777-785

  Morris, Meg E ^a   Menz, Hylton B ^a   McGinley, Jennifer L ^b   Watts, Jennifer J ^c   Huxham, Frances E ^a   Murphy, Anna T ^d   Danoudis, Mary E ^a   Iansek, Robert ^a,d  

^a LA TROBE UNIVERSITY   (Australia)

^b UNIVERSITY OF MELBOURNE   (Australia)

^c DEAKIN UNIVERSITY   (Australia)

^d Kingston Centre   (Australia)

Author keywords

falls prevention; movement strategy training; Parkinson's disease; physical therapy; progressive resistance strength training

Indexed keywords

ANTIPARKINSON AGENT; LEVODOPA; PRESCRIPTION DRUG;

AGED; ARTICLE; COMPARATIVE EFFECTIVENESS; CONTROLLED STUDY; DISABILITY; EVIDENCE BASED PRACTICE; FALL RISK; FALLING; FEASIBILITY STUDY; FEMALE; FOLLOW UP; HOME REHABILITATION; HUMAN; INTERVENTION STUDY; MAJOR CLINICAL STUDY; MALE; MOVEMENT STRATEGY TRAINING; OUTPATIENT CARE; PARKINSON DISEASE; PATIENT EDUCATION; PHYSIOTHERAPY; PRESCRIPTION; PROGRESSIVE RESISTANCE STRENGTH TRAINING; PROSPECTIVE STUDY; QUALITY OF LIFE; RANDOMIZED CONTROLLED TRIAL; RISK REDUCTION; SINGLE BLIND PROCEDURE; TREATMENT OUTCOME; WALKING SPEED; ADULT; COMPARATIVE STUDY; MIDDLE AGED; PATHOPHYSIOLOGY; PHYSIOLOGY; PREVENTION AND CONTROL; PROCEDURES; PSYCHOLOGY; RESISTANCE TRAINING; VERY ELDERLY; WALKING;

ACCIDENTAL FALLS; ADULT; AGED; AGED, 80 AND OVER; DISABILITY EVALUATION; FEASIBILITY STUDIES; FEMALE; FOLLOW-UP STUDIES; HUMANS; MALE; MIDDLE AGED; PARKINSON DISEASE; PATIENT EDUCATION AS TOPIC; PHYSICAL THERAPY MODALITIES; PROSPECTIVE STUDIES; QUALITY OF LIFE; RESISTANCE TRAINING; SINGLE-BLIND METHOD; TREATMENT OUTCOME; WALKING;

EID: 84940106462     PISSN: 15459683     EISSN: 15526844     Source Type: Journal    
DOI: 10.1177/1545968314565511     Document Type: Article

References (45)

1. Ashburn A, Stack E, Pickering RM, Ward CD,. A community-dwelling sample of people with Parkinson's disease: characteristics of fallers and non-fallers. Age Ageing. 2001; 30: 47-52.
2. Bloem BR, van Vugt JP, Beckley DJ,. Postural instability and falls in Parkinson's disease. Adv Neurol. 2001; 87: 209-223.
3. Ellis T, de Goede CJ, Feldman RG, Wolters EC, Kwakkel G, Wagenaar RC,. Efficacy of a physical therapy program in patients with Parkinson's disease: a randomized controlled trial. Arch Phys Med Rehabil. 2005; 86: 626-632.
4. Goodwin VA, Richards SH, Henley W, Ewings P, Taylor AH, Campbell JL,. An exercise intervention to prevent falls in people with Parkinson's disease: a pragmatic randomised controlled trial. J Neurol Neurosurg Psychiatry. 2011; 82: 1232-1238.
5. Li F, Harmer P, Fitzgerald K,. Tai chi and postural stability in patients with Parkinson's disease. N Engl J Med. 2012; 366: 511-519.
6. Munneke M, Nijkrake MJ, Keus SH,. Efficacy of community-based physiotherapy networks for patients with Parkinson's disease: a cluster-randomised trial. Lancet Neurol. 2010; 9: 46-54.
7. Nieuwboer A, Kwakkel G, Rochester L,. Cueing training in the home improves gait-related mobility in Parkinson's disease: the RESCUE trial. J Neurol Neurosurg Psychiatry. 2007; 78: 134-140.
8. Rochester L, Rafferty D, Dotchin C, Msuya O, Minde V, Walker RW,. The effect of cueing therapy on single and dual-task gait in a drug naive population of people with Parkinson's disease in northern Tanzania. Mov Disord. 2010; 25: 906-911.
9. Lamb SE, Jorstad-Stein EC, Hauer K, Becker C,. Development of a common outcome data set for fall injury prevention trials: the Prevention of Falls Network Europe consensus. J Am Geriatr Soc. 2005; 53: 1618-1622.
10. Fletcher E, Goodwin VA, Richards SH, Campbell JL, Taylor RS,. An exercise intervention to prevent falls in Parkinson's: an economic evaluation. BMC Health Serv Res. 2012; 12: 4262013.
11. Mak MK, Pang MY,. Fear of falling is independently associated with recurrent falls in patients with Parkinson's disease: a 1-year prospective study. J Neurol. 2009; 256: 1689-1695.
12. Nilsson MH, Drake AM, Hagell P,. Assessment of fall-related self-efficacy and activity avoidance in people with Parkinson's disease. BMC Geriatr. 2010; 10: 78.
13. Giladi N, Hausdorff JM,. The role of mental function in the pathogenesis of freezing of gait in Parkinson's disease. J Neurol Sci. 2006; 248: 173-176.
14. Rahman S, Griffin HJ, Quinn NP, Jahanshahi M,. Quality of life in Parkinson's disease: the relative importance of the symptoms. Mov Disord. 2008; 23: 1428-1434.
15. Morris ME, Menz HB, McGinley JL,. Falls and mobility in Parkinson's disease: protocol for a randomised controlled clinical trial. BMC Neurol. 2011; 11: 93.
16. McGinley JL, Martin C, Huxham FE,. Feasibility, safety, and compliance in a randomized controlled trial of physical therapy for Parkinson's disease. Parkinsons Dis. 2012; 2012: 795294.
17. Watts JJ, McGinley JL, Huxham F,. Cost effectiveness of preventing falls and improving mobility in people with Parkinson disease: protocol for an economic evaluation alongside a clinical trial. BMC Geriatr. 2008; 8: 23.
18. Folstein MF, Folstein SE,. Mini-mental state: a practical method for grading the cognitive state of patients for the clinician. J Psychiatr Res. 1975; 12: 189-198.
19. Hoehn MM, Yahr MD,. Parkinsonism: onset, progression and mortality. Neurology. 1967; 17: 427-442.
20. Commonwealth of Australia. Don't Fall for It. Falls Can Be Prevented!-A Guide to Preventing Falls for Older People. Canberra, Australia: Commonwealth of Australia; 2007.
21. Foster C, Florhaug JA, Franklin J,. A new approach to monitoring exercise training. J Strength Cond Res. 2001; 15: 109-115.
22. Fahn S, Elton RL,. Unified Parkinson's disease rating scale. In: Fahn S, Marsden C, Calne D, Goldstein M, eds. Recent Developments in Parkinson's Disease. New York, NY: Macmillan, 1987: 153-163.
23. Lam HS, Lau FW, Chan GK, Sykes K,. The validity and reliability of a 6-Metre Timed Walk for the functional assessment of patients with stroke. Physiother Theory Pract. 2010; 26: 251-255.
24. Podsiadlo D, Richardson S,. The timed '€'Up & Go'€': a test of basic functional mobility for frail elderly persons. J Am Geriatr Soc. 1991; 39: 142-148.
25. Jenkinson C, Peto V, Fitzpatrick R, Greenhall R, Hyman N,. Self-reported functioning and well-being in patients with Parkinson's disease: comparison of the Short-Form Health Survey (SF-36) and the Parkinson's Disease Questionnaire (PDQ-39). Age Ageing. 1995; 24: 505-509.
26. The EuroQol Group. EuroQol-a new facility for the measurement of health-related quality of life. Health Policy 1990; 16: 199-208.
27. Morris M, Osborne D, Hill K,. Predisposing factors for occasional and multiple falls in older Australians who live at home. Aust J Physiother. 2004; 50: 153-159.
28. Morris S, Morris ME, Iansek R,. Reliability of measurements obtained with the Timed '€'Up & Go'€' test in people with Parkinson disease. Phys Ther. 2001; 81: 810-818.
29. Urquhart DM, Morris ME, Iansek R,. Gait consistency over a 7-day interval in people with Parkinson's disease. Arch Phys Med Rehabil. 1999; 80: 696-701.
30. Robertson MC, Campbell AJ, Herbison P,. Statistical analysis of efficacy in falls prevention trials. J Gerontol A Biol Sci Med Sci. 2005; 60: 530-534.
31. Twisk J, Proper K,. Evaluation of the results of a randomized controlled trial: how to define changes between baseline and follow-up. J Clin Epidemiol. 2004; 57: 223-228.
32. Pocock SJ,. When (not) to stop a clinical trial for benefit. JAMA. 2005; 294: 2228-2230.
33. Bassler D, Briel M, Montori VM,. Stopping randomized trials early for benefit and estimation of treatment effects: systematic review and meta-regression analysis. JAMA. 2010; 303: 1180-1187.
34. Day L,. The Otago strength and balance exercise programme lowers the risk of death and falls in the older people at 12 months. Evid Based Nurs. 2011; 14: 76-78.
35. Morris ME, Iansek R, Matyas TA, Summers JJ,. Stride length regulation in Parkinson's disease. Normalization strategies and underlying mechanisms. Brain. 1996; 119: 551-568.
36. Paul SS, Canning CG, Song J, Fung VS, Sherrington C,. Leg muscle power is enhanced by training in people with Parkinson's disease: a randomized controlled trial. Clin Rehabil. 2014; 28: 275-288.
37. Morberg BM, Jensen J, Bode M, Wermuth L,. The impact of high intensity physical training on motor and non-motor symptoms in patients with Parkinson's disease (PIP): a preliminary study. NeuroRehabilitation. 2014; 35: 291-298.
38. Frazzitta G, Maestri R, Ghilardi MF,. Intensive rehabilitation increases BDNF serum levels in parkinsonian patients: a randomized study. Neurorehabil Neural Repair. 2014; 28: 163-168.
39. Wood BH, Bilclough JA, Bowron A, Walker RW,. Incidence and prediction of falls in Parkinson's disease: a prospective multidisciplinary study. J Neurol Neurosurg Psychiatry. 2002; 72: 721-725.
40. Ashburn A, Stack E, Pickering RM, Ward CD,. Predicting fallers in a community-based sample of people with Parkinson's disease. Gerontology. 2001; 47: 277-281.
41. Bloem BR, Grimbergen YA, Cramer M, Willemsen M, Zwinderman AH,. Prospective assessment of falls in Parkinson's disease. J Neurol. 2001; 248: 950-958.
42. Mak MK, Pang MY,. Parkinsonian single fallers versus recurrent fallers: different fall characteristics and clinical features. J Neurol. 2010; 257: 1543-1551.
43. Matinolli M, Korpelainen JT, Sotaniemi KA, Myllyla VV, Korpelainen R,. Recurrent falls and mortality in Parkinson's disease: a prospective two-year follow-up study. Acta Neurol Scand. 2011; 123: 193-200.
44. Johnell O, Melton LJ 3rd, Atkinson EJ, O'Fallon WM, Kurland LT,. Fracture risk in patients with parkinsonism: a population-based study in Olmsted County, Minnesota. Age Ageing. 1992; 21: 32-38.
45. Morris ME,. Preventing falls in older people. BMJ. 2012; 345: e4919.