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Volumn , Issue , 2008, Pages 55-90

Structural and Biochemical Changes in Aging Skin and Their Impact on Skin Permeability Barrier

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EID: 84940079167     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1016/B978-0-8155-1584-5.50008-9     Document Type: Chapter
Times cited : (5)

References (108)
  • 1
    • 0015904601 scopus 로고
    • "The thickness of the epidermis."
    • Whitton JT, Everall JD "The thickness of the epidermis.". Br J Dermatol 1973, 89(5):467-476.
    • (1973) Br J Dermatol , vol.89 , Issue.5 , pp. 467-476
    • Whitton, J.T.1    Everall, J.D.2
  • 2
    • 0028960479 scopus 로고
    • "The aged epidermal permeability barrier. Structural, functional, and lipid biochemical abnormalities in humans and a senescent murine model."
    • Ghadially R, et al. "The aged epidermal permeability barrier. Structural, functional, and lipid biochemical abnormalities in humans and a senescent murine model.". J Clin Invest 1995, 95(5):2281-2290.
    • (1995) J Clin Invest , vol.95 , Issue.5 , pp. 2281-2290
    • Ghadially, R.1
  • 3
    • 0024550570 scopus 로고
    • "Histopathologic characteristics and ultrastructure of aging skin."
    • Smith L "Histopathologic characteristics and ultrastructure of aging skin.". Cutis 1989, 43(5):414-424.
    • (1989) Cutis , vol.43 , Issue.5 , pp. 414-424
    • Smith, L.1
  • 4
    • 0014566953 scopus 로고
    • "A modified radiographic method for measuring skin thickness."
    • Black MM "A modified radiographic method for measuring skin thickness.". Br J Dermatol 1969, 81(9):661-666.
    • (1969) Br J Dermatol , vol.81 , Issue.9 , pp. 661-666
    • Black, M.M.1
  • 5
    • 0018577872 scopus 로고
    • "Structural alterations in exposed and unexposed aged skin."
    • Lavker RM "Structural alterations in exposed and unexposed aged skin.". J Invest Dermatol 1979, 73(1):59-66.
    • (1979) J Invest Dermatol , vol.73 , Issue.1 , pp. 59-66
    • Lavker, R.M.1
  • 6
    • 0020073049 scopus 로고
    • "Effect of chronologic aging and ultraviolet irradiation on Langerhans cells in human epidermis."
    • Gilchrest BA, Murphy GF, Soter NA "Effect of chronologic aging and ultraviolet irradiation on Langerhans cells in human epidermis.". J Invest Dermatol 1982, 79(2):85-88.
    • (1982) J Invest Dermatol , vol.79 , Issue.2 , pp. 85-88
    • Gilchrest, B.A.1    Murphy, G.F.2    Soter, N.A.3
  • 7
    • 0019942138 scopus 로고
    • "Chronologic aging alters the response to ultraviolet-induced inflammation in human skin."
    • Gilchrest BA, Stoff JS, Soter NA "Chronologic aging alters the response to ultraviolet-induced inflammation in human skin.". J Invest Dermatol 1982, 79(1):11-15.
    • (1982) J Invest Dermatol , vol.79 , Issue.1 , pp. 11-15
    • Gilchrest, B.A.1    Stoff, J.S.2    Soter, N.A.3
  • 8
    • 0018609894 scopus 로고
    • "Effects of aging and chronic sun exposure on melanocytes in human skin."
    • Gilchrest BA, Blog FB, Szabo G "Effects of aging and chronic sun exposure on melanocytes in human skin.". J Invest Dermatol 1979, 73(2):141-143.
    • (1979) J Invest Dermatol , vol.73 , Issue.2 , pp. 141-143
    • Gilchrest, B.A.1    Blog, F.B.2    Szabo, G.3
  • 9
    • 33744508373 scopus 로고    scopus 로고
    • "Telomere length of the skin in association with chronological aging and photoaging."
    • Sugimoto M, Yamashita R, Ueda M "Telomere length of the skin in association with chronological aging and photoaging.". J Dermatol Sci 2006, 43(1):43-47.
    • (2006) J Dermatol Sci , vol.43 , Issue.1 , pp. 43-47
    • Sugimoto, M.1    Yamashita, R.2    Ueda, M.3
  • 10
    • 27744504762 scopus 로고    scopus 로고
    • "Age and skin structure and function, a quantitative approach (I): blood flow, pH, thickness, and ultrasound echogenicity."
    • Waller JM, Maibach HI "Age and skin structure and function, a quantitative approach (I): blood flow, pH, thickness, and ultrasound echogenicity.". Skin Res Technol 2005, 11(4):221-235.
    • (2005) Skin Res Technol , vol.11 , Issue.4 , pp. 221-235
    • Waller, J.M.1    Maibach, H.I.2
  • 11
    • 0014071596 scopus 로고
    • "Technique for estimating turnover time of human stratum corneum."
    • Baker H, Kligman AM "Technique for estimating turnover time of human stratum corneum.". Arch Dermatol 1967, 95(4):408-411.
    • (1967) Arch Dermatol , vol.95 , Issue.4 , pp. 408-411
    • Baker, H.1    Kligman, A.M.2
  • 12
    • 0014066429 scopus 로고
    • "A simple in vivo method for studying the permeability of the human stratum corneum."
    • Baker H, Kligman AM "A simple in vivo method for studying the permeability of the human stratum corneum.". J Invest Dermatol 1967, 48(3):273-274.
    • (1967) J Invest Dermatol , vol.48 , Issue.3 , pp. 273-274
    • Baker, H.1    Kligman, A.M.2
  • 13
    • 0017911804 scopus 로고
    • "Age-related differences in the rate of desquamation of skin surface cells [proceedings]."
    • Leyden JJ, et al. "Age-related differences in the rate of desquamation of skin surface cells [proceedings].". Adv Exp Med Biol 1978, 97:297-298.
    • (1978) Adv Exp Med Biol , vol.97 , pp. 297-298
    • Leyden, J.J.1
  • 14
    • 0014143018 scopus 로고
    • "Skin resistance, sweat-gland counts, salivary flow, and gastric secretion: age, race, and sex differences, and intercorrelations."
    • Juniper K, Dykman RA "Skin resistance, sweat-gland counts, salivary flow, and gastric secretion: age, race, and sex differences, and intercorrelations.". Psychophysiology 1967, 4(2):216-222.
    • (1967) Psychophysiology , vol.4 , Issue.2 , pp. 216-222
    • Juniper, K.1    Dykman, R.A.2
  • 15
    • 13144260549 scopus 로고
    • "Nail changes with aging."
    • Raven Press, New York, A. Kligman, A. Balin (Eds.)
    • Orentreich N, Durr P "Nail changes with aging.". Aging and the Skin 1989, 285. Raven Press, New York. A. Kligman, A. Balin (Eds.).
    • (1989) Aging and the Skin , pp. 285
    • Orentreich, N.1    Durr, P.2
  • 16
    • 0026337850 scopus 로고
    • "Regional differences in the sweating responses of older and younger men."
    • Inoue Y, et al. "Regional differences in the sweating responses of older and younger men.". J Appl Physiol 1991, 71(6):2453-2459.
    • (1991) J Appl Physiol , vol.71 , Issue.6 , pp. 2453-2459
    • Inoue, Y.1
  • 17
    • 0022397424 scopus 로고
    • "Age-related changes in sebaceous wax ester secretion rates in men and women."
    • Jacobsen E, et al. "Age-related changes in sebaceous wax ester secretion rates in men and women.". J Invest Dermatol 1985, 85(5):483-485.
    • (1985) J Invest Dermatol , vol.85 , Issue.5 , pp. 483-485
    • Jacobsen, E.1
  • 18
    • 0018194339 scopus 로고
    • "Proliferative activity of the sebaceous glands of the aged."
    • Plewig G, Kligman AM "Proliferative activity of the sebaceous glands of the aged.". J Invest Dermatol 1978, 70(6):314-317.
    • (1978) J Invest Dermatol , vol.70 , Issue.6 , pp. 314-317
    • Plewig, G.1    Kligman, A.M.2
  • 19
    • 0018612990 scopus 로고
    • "Age-related changes in sebaceous gland activity."
    • Pochi PE, Strauss JS, Downing DT "Age-related changes in sebaceous gland activity.". J Invest Dermatol 1979, 73(1):108-111.
    • (1979) J Invest Dermatol , vol.73 , Issue.1 , pp. 108-111
    • Pochi, P.E.1    Strauss, J.S.2    Downing, D.T.3
  • 20
    • 0035948752 scopus 로고    scopus 로고
    • "The influence of hormone replacement therapy on skin ageing: a pilot study."
    • Sator PG, et al. "The influence of hormone replacement therapy on skin ageing: a pilot study.". Maturitas 2001, 39(1):43-55.
    • (2001) Maturitas , vol.39 , Issue.1 , pp. 43-55
    • Sator, P.G.1
  • 21
    • 0015950879 scopus 로고
    • "Endocrinologic control of the development and activity of the human sebaceous gland."
    • Pochi PE, Strauss JS "Endocrinologic control of the development and activity of the human sebaceous gland.". J Invest Dermatol 1974, 62(3):191-201.
    • (1974) J Invest Dermatol , vol.62 , Issue.3 , pp. 191-201
    • Pochi, P.E.1    Strauss, J.S.2
  • 22
    • 0042178374 scopus 로고    scopus 로고
    • "The biological actions of estrogens on skin."
    • Thornton MJ "The biological actions of estrogens on skin.". Exp Dermatol 2002, 11(6):487-502.
    • (2002) Exp Dermatol , vol.11 , Issue.6 , pp. 487-502
    • Thornton, M.J.1
  • 23
    • 0006459505 scopus 로고
    • "Nerve changes in aging skin."
    • Permagon Press, Oxford, W. Montagna (Ed.)
    • Winkelmann RK "Nerve changes in aging skin.". Advances in the Biology of the Skin 1964, 51. Permagon Press, Oxford. W. Montagna (Ed.).
    • (1964) Advances in the Biology of the Skin , pp. 51
    • Winkelmann, R.K.1
  • 24
    • 0035192846 scopus 로고    scopus 로고
    • "Graying: gerontobiology of the hair follicle pigmentary unit."
    • Tobin DJ, Paus R "Graying: gerontobiology of the hair follicle pigmentary unit.". Exp Gerontol 2001, 36(1):29-54.
    • (2001) Exp Gerontol , vol.36 , Issue.1 , pp. 29-54
    • Tobin, D.J.1    Paus, R.2
  • 25
    • 14644409434 scopus 로고
    • "Keratin replacement as an aging parameter."
    • Orentreich N, Sharp N "Keratin replacement as an aging parameter.". J Soc Cosm Chem 1967, 18:537-547.
    • (1967) J Soc Cosm Chem , vol.18 , pp. 537-547
    • Orentreich, N.1    Sharp, N.2
  • 26
    • 0022543938 scopus 로고
    • "Structural and functional changes of normal aging skin."
    • Fenske NA, Lober CW "Structural and functional changes of normal aging skin.". J Am Acad Dermatol 1986, 15(4 Pt 1):571-585.
    • (1986) J Am Acad Dermatol , vol.15 , Issue.4 , pp. 571-585
    • Fenske, N.A.1    Lober, C.W.2
  • 27
    • 0008497459 scopus 로고
    • "The cutaneous innervation of human newborn prepuce."
    • Winkelmann RK "The cutaneous innervation of human newborn prepuce.". J Invest Dermatol 1956, 26(1):53-67.
    • (1956) J Invest Dermatol , vol.26 , Issue.1 , pp. 53-67
    • Winkelmann, R.K.1
  • 30
    • 0014465980 scopus 로고
    • "The elastic fiber. I. The separation and partial characterization of its macromolecular components."
    • Ross R, Bornstein P "The elastic fiber. I. The separation and partial characterization of its macromolecular components.". J Cell Biol 1969, 40(2):366-381.
    • (1969) J Cell Biol , vol.40 , Issue.2 , pp. 366-381
    • Ross, R.1    Bornstein, P.2
  • 31
    • 0024604501 scopus 로고
    • "Extracellular matrix of the skin: 50 years of progress."
    • Uitto J, Olsen DR, Fazio MJ "Extracellular matrix of the skin: 50 years of progress.". J Invest Dermatol 1989, 92(4 Suppl):61S-77S.
    • (1989) J Invest Dermatol , vol.92 , Issue.4 , pp. 61S-77S
    • Uitto, J.1    Olsen, D.R.2    Fazio, M.J.3
  • 32
    • 0022806825 scopus 로고
    • "UCLA conference. Biochemistry of collagen in diseases."
    • Uitto J, et al. "UCLA conference. Biochemistry of collagen in diseases.". Ann Intern Med 1986, 105(5):740-756.
    • (1986) Ann Intern Med , vol.105 , Issue.5 , pp. 740-756
    • Uitto, J.1
  • 34
    • 0025799478 scopus 로고
    • "The origin of matrix metalloproteinases and their familial relationships."
    • Murphy GJ, Murphy G, Reynolds JJ "The origin of matrix metalloproteinases and their familial relationships.". FEBS Lett 1991, 289(1):4-7.
    • (1991) FEBS Lett , vol.289 , Issue.1 , pp. 4-7
    • Murphy, G.J.1    Murphy, G.2    Reynolds, J.J.3
  • 35
    • 0024349034 scopus 로고
    • "Molecular mechanisms of cutaneous aging. Age-associated connective tissue alterations in the dermis."
    • Uitto J, Fazio MJ, Olsen DR "Molecular mechanisms of cutaneous aging. Age-associated connective tissue alterations in the dermis.". J Am Acad Dermatol 1989, 21(3 Pt 2):614-622.
    • (1989) J Am Acad Dermatol , vol.21 , Issue.3 , pp. 614-622
    • Uitto, J.1    Fazio, M.J.2    Olsen, D.R.3
  • 36
    • 0016358948 scopus 로고
    • "Biological significance of the intermolecular crosslinks of collagen."
    • Bailey AJ, Robins SP, Balian G "Biological significance of the intermolecular crosslinks of collagen.". Nature 1974, 251(5471):105-109.
    • (1974) Nature , vol.251 , Issue.5471 , pp. 105-109
    • Bailey, A.J.1    Robins, S.P.2    Balian, G.3
  • 37
    • 0014960323 scopus 로고
    • "A method for studying collagen biosynthesis in human skin biopsies in vitro."
    • Uitto J "A method for studying collagen biosynthesis in human skin biopsies in vitro.". Biochim Biophys Acta 1970, 201(3):438-445.
    • (1970) Biochim Biophys Acta , vol.201 , Issue.3 , pp. 438-445
    • Uitto, J.1
  • 38
    • 0141616315 scopus 로고    scopus 로고
    • "Vitamin A antagonizes decreased cell growth and elevated collagen-degrading matrix metalloproteinases and stimulates collagen accumulation in naturally aged human skin."
    • Varani J, et al. "Vitamin A antagonizes decreased cell growth and elevated collagen-degrading matrix metalloproteinases and stimulates collagen accumulation in naturally aged human skin.". J Invest Dermatol 2000, 114(3):480-486.
    • (2000) J Invest Dermatol , vol.114 , Issue.3 , pp. 480-486
    • Varani, J.1
  • 39
    • 0026006498 scopus 로고
    • "Integrin alpha 2 beta 1 (VLA-2) mediates reorganization and contraction of collagen matrices by human cells."
    • Schiro JA, et al. "Integrin alpha 2 beta 1 (VLA-2) mediates reorganization and contraction of collagen matrices by human cells.". Cell 1991, 67(2):403-410.
    • (1991) Cell , vol.67 , Issue.2 , pp. 403-410
    • Schiro, J.A.1
  • 40
    • 0033035808 scopus 로고    scopus 로고
    • "Absence of integrin alpha1beta1 in the mouse causes loss of feedback regulation of collagen synthesis in normal and wounded dermis."
    • Gardner H, et al. "Absence of integrin alpha1beta1 in the mouse causes loss of feedback regulation of collagen synthesis in normal and wounded dermis.". J Cell Sci 1999, 112(Pt 3):263-272.
    • (1999) J Cell Sci , vol.112 , Issue.PT 3 , pp. 263-272
    • Gardner, H.1
  • 41
    • 0035108458 scopus 로고    scopus 로고
    • "Inhibition of type I procollagen synthesis by damaged collagen in photoaged skin and by collagenase-degraded collagen in vitro."
    • Varani J, Spearman D, Perone P, Fligiel SE, et al. "Inhibition of type I procollagen synthesis by damaged collagen in photoaged skin and by collagenase-degraded collagen in vitro.". Am J Pathol 2001, 158(3):931-942.
    • (2001) Am J Pathol , vol.158 , Issue.3 , pp. 931-942
    • Varani, J.1    Spearman, D.2    Perone, P.3    Fligiel, S.E.4
  • 42
    • 0032401898 scopus 로고    scopus 로고
    • "Mechanisms of maturation and ageing of collagen."
    • Bailey AJ, Paul RG, Knott L "Mechanisms of maturation and ageing of collagen.". Mech Ageing Dev 1998, 106(1-2):1-56.
    • (1998) Mech Ageing Dev , vol.106 , Issue.1-2 , pp. 1-56
    • Bailey, A.J.1    Paul, R.G.2    Knott, L.3
  • 43
    • 0031281802 scopus 로고    scopus 로고
    • "Single-column high-performance liquid chromatographic-fluorescence detection of immature, mature, and senescent cross-links of collagen."
    • Saito M, et al. "Single-column high-performance liquid chromatographic-fluorescence detection of immature, mature, and senescent cross-links of collagen.". Anal Biochem 1997, 253(1):26-32.
    • (1997) Anal Biochem , vol.253 , Issue.1 , pp. 26-32
    • Saito, M.1
  • 44
    • 1242322193 scopus 로고    scopus 로고
    • "Skin aging and natural photoprotection."
    • Wulf HC, et al. "Skin aging and natural photoprotection.". Micron 2004, 35(3):185-191.
    • (2004) Micron , vol.35 , Issue.3 , pp. 185-191
    • Wulf, H.C.1
  • 45
    • 0020049070 scopus 로고
    • "Studies in cutaneous aging: I. The elastic fiber network."
    • Braverman IM, Fonferko E "Studies in cutaneous aging: I. The elastic fiber network.". J Invest Dermatol 1982, 78(5):434-443.
    • (1982) J Invest Dermatol , vol.78 , Issue.5 , pp. 434-443
    • Braverman, I.M.1    Fonferko, E.2
  • 46
    • 0018638134 scopus 로고
    • "Structural changes in aging human skin."
    • Montagna W, Carlisle K "Structural changes in aging human skin.". J Invest Dermatol 1979, 73(1):47-53.
    • (1979) J Invest Dermatol , vol.73 , Issue.1 , pp. 47-53
    • Montagna, W.1    Carlisle, K.2
  • 47
    • 0019483813 scopus 로고
    • "Age-related changes in human dermal elastic fibres."
    • Tsuji T, Hamada T "Age-related changes in human dermal elastic fibres.". Br J Dermatol 1981, 105(1):57-63.
    • (1981) Br J Dermatol , vol.105 , Issue.1 , pp. 57-63
    • Tsuji, T.1    Hamada, T.2
  • 48
    • 0036783292 scopus 로고    scopus 로고
    • "Intrinsic aging vs. photoaging: a comparative histopathological, immunohistochemical, and ultrastructural study of skin."
    • El-Domyati M, et al. "Intrinsic aging vs. photoaging: a comparative histopathological, immunohistochemical, and ultrastructural study of skin.". Exp Dermatol 2002, 11(5):398-405.
    • (2002) Exp Dermatol , vol.11 , Issue.5 , pp. 398-405
    • El-Domyati, M.1
  • 49
    • 0021794133 scopus 로고
    • "The anatomy and pathogenesis of wrinkles."
    • Kligman AM, Zheng P, Lavker RM "The anatomy and pathogenesis of wrinkles.". Br J Dermatol 1985, 113(1):37-42.
    • (1985) Br J Dermatol , vol.113 , Issue.1 , pp. 37-42
    • Kligman, A.M.1    Zheng, P.2    Lavker, R.M.3
  • 50
    • 0023948122 scopus 로고
    • "Isolation and characterization of human elastin cDNAs, and age-associated variation in elastin gene expression in cultured skin fibroblasts."
    • Fazio MJ, et al. "Isolation and characterization of human elastin cDNAs, and age-associated variation in elastin gene expression in cultured skin fibroblasts.". Lab Invest 1988, 58(3):270-277.
    • (1988) Lab Invest , vol.58 , Issue.3 , pp. 270-277
    • Fazio, M.J.1
  • 51
    • 84882864250 scopus 로고
    • "Mucopolysaccharides of ground substances."
    • McGraw-Hill, New York, T.B. Fitzpatrick (Ed.)
    • Silbert J "Mucopolysaccharides of ground substances.". Dermatology in General Medicine 1987, McGraw-Hill, New York. T.B. Fitzpatrick (Ed.).
    • (1987) Dermatology in General Medicine
    • Silbert, J.1
  • 52
    • 0023927040 scopus 로고
    • "Proteoglycan-fibrillar collagen interactions."
    • Scott JE "Proteoglycan-fibrillar collagen interactions.". Biochem J 1988, 252(2):313-323.
    • (1988) Biochem J , vol.252 , Issue.2 , pp. 313-323
    • Scott, J.E.1
  • 53
    • 0344877141 scopus 로고
    • "The role of glycosaminoglycans in aging of the skin."
    • Raven Press, New York, A. Kligman, A. Balin (Eds.)
    • Perlish J "The role of glycosaminoglycans in aging of the skin.". Aging and the Skin 1989, Raven Press, New York. A. Kligman, A. Balin (Eds.).
    • (1989) Aging and the Skin
    • Perlish, J.1
  • 55
    • 0028325164 scopus 로고
    • "Hyaluronic acid in cutaneous intrinsic aging."
    • Ghersetich I, et al. "Hyaluronic acid in cutaneous intrinsic aging.". Int J Dermatol 1994, 33(2):119-122.
    • (1994) Int J Dermatol , vol.33 , Issue.2 , pp. 119-122
    • Ghersetich, I.1
  • 56
    • 0023653737 scopus 로고
    • "Evidence for structural changes in dermatan sulfate and hyaluronic acid with aging."
    • Longas MO, Russell CS, HE XY "Evidence for structural changes in dermatan sulfate and hyaluronic acid with aging.". Carbohydr Res 1987, 159(1):127-136.
    • (1987) Carbohydr Res , vol.159 , Issue.1 , pp. 127-136
    • Longas, M.O.1    Russell, C.S.2    H.E, X.Y.3
  • 57
    • 0025903538 scopus 로고
    • "Patterns of glycosaminoglycan/proteoglycan immunostaining in human skin during aging."
    • Willen MD, et al. "Patterns of glycosaminoglycan/proteoglycan immunostaining in human skin during aging.". J Invest Dermatol 1991, 96(6):968-974.
    • (1991) J Invest Dermatol , vol.96 , Issue.6 , pp. 968-974
    • Willen, M.D.1
  • 58
    • 0034007098 scopus 로고    scopus 로고
    • "Further evidence of a decorin-collagen interaction in the disruption of cervical collagen fibers during rat gestation."
    • discussion 811-2
    • Leppert PC, et al. "Further evidence of a decorin-collagen interaction in the disruption of cervical collagen fibers during rat gestation.". Am J Obstet Gynecol 2000, 182(4):805-811. discussion 811-2.
    • (2000) Am J Obstet Gynecol , vol.182 , Issue.4 , pp. 805-811
    • Leppert, P.C.1
  • 60
    • 0014712534 scopus 로고
    • "Regional differences of cell sizes in the human stratum corneum. II. Effects of sex and age."
    • Plewig G "Regional differences of cell sizes in the human stratum corneum. II. Effects of sex and age.". J Invest Dermatol 1970, 54(1):19-23.
    • (1970) J Invest Dermatol , vol.54 , Issue.1 , pp. 19-23
    • Plewig, G.1
  • 61
    • 1342280466 scopus 로고    scopus 로고
    • "Stratum corneum maturation. A review of neonatal skin function."
    • Chiou YB, Blume-Peytavi U "Stratum corneum maturation. A review of neonatal skin function.". Skin Pharmacol Physiol 2004, 17(2):57-66.
    • (2004) Skin Pharmacol Physiol , vol.17 , Issue.2 , pp. 57-66
    • Chiou, Y.B.1    Blume-Peytavi, U.2
  • 62
    • 84882812173 scopus 로고
    • "The normal skin from birth to adolescence."
    • Grune & Stratton, Philadelphia, R. Ruiz-Maldonado, L. Parish, J. Beare (Eds.)
    • Cappugi P, Battini M "The normal skin from birth to adolescence.". Textbook of Pediatric Dermatology 1989, 7-20. Grune & Stratton, Philadelphia. R. Ruiz-Maldonado, L. Parish, J. Beare (Eds.).
    • (1989) Textbook of Pediatric Dermatology , pp. 7-20
    • Cappugi, P.1    Battini, M.2
  • 63
    • 0345577245 scopus 로고
    • "Structure of fetal and neonatal skin."
    • Saunders, Philadelphia, L. Solomon, N. Esterly (Eds.)
    • Solomon L, Esterly N "Structure of fetal and neonatal skin.". Neonatal Dermatology 1973, 1-16. Saunders, Philadelphia. L. Solomon, N. Esterly (Eds.).
    • (1973) Neonatal Dermatology , pp. 1-16
    • Solomon, L.1    Esterly, N.2
  • 64
    • 0014734626 scopus 로고
    • "Chemical composition of human skin surface lipids from birth to puberty."
    • Ramasastry P, et al. "Chemical composition of human skin surface lipids from birth to puberty.". J Invest Dermatol 1970, 54(2):139-144.
    • (1970) J Invest Dermatol , vol.54 , Issue.2 , pp. 139-144
    • Ramasastry, P.1
  • 65
    • 0035013520 scopus 로고    scopus 로고
    • "Skin barrier, hydration, and pH of the skin of infants under 2 years of age."
    • Giusti F, et al. "Skin barrier, hydration, and pH of the skin of infants under 2 years of age.". Pediatr Dermatol 2001, 18(2):93-96.
    • (2001) Pediatr Dermatol , vol.18 , Issue.2 , pp. 93-96
    • Giusti, F.1
  • 66
    • 0029091102 scopus 로고
    • "Surface electrical capacitance as a noninvasive bedside measure of epidermal barrier maturation in the newborn infant."
    • Okah FA, et al. "Surface electrical capacitance as a noninvasive bedside measure of epidermal barrier maturation in the newborn infant.". Pediatrics 1995, 96(4 Pt 1):688-692.
    • (1995) Pediatrics , vol.96 , Issue.4 , pp. 688-692
    • Okah, F.A.1
  • 67
    • 0016360356 scopus 로고
    • "Insensible water loss in preterm infants: changes with postnatal development and non-ionizing radiant energy."
    • Wu PY, Hodgman JE "Insensible water loss in preterm infants: changes with postnatal development and non-ionizing radiant energy.". Pediatrics 1974, 54(6):704-712.
    • (1974) Pediatrics , vol.54 , Issue.6 , pp. 704-712
    • Wu, P.Y.1    Hodgman, J.E.2
  • 68
    • 0018605086 scopus 로고
    • "Water loss from the skin of term and preterm babies."
    • Rutter N, Hull D "Water loss from the skin of term and preterm babies.". Arch Dis Child 1979, 54(11):858-868.
    • (1979) Arch Dis Child , vol.54 , Issue.11 , pp. 858-868
    • Rutter, N.1    Hull, D.2
  • 69
    • 0033917685 scopus 로고    scopus 로고
    • "Skin barrier properties in different body areas in neonates."
    • Yosipovitch G, et al. "Skin barrier properties in different body areas in neonates.". Pediatrics 2000, 106(1 Pt 1):105-108.
    • (2000) Pediatrics , vol.106 , Issue.1 , pp. 105-108
    • Yosipovitch, G.1
  • 70
    • 0014237315 scopus 로고
    • "Physiologic skin pH patterns in infants of low birth weight. The onset of surface acidification."
    • Green M, Carol B, Behrendt H "Physiologic skin pH patterns in infants of low birth weight. The onset of surface acidification.". Am J Dis Child 1968, 115(1):9-16.
    • (1968) Am J Dis Child , vol.115 , Issue.1 , pp. 9-16
    • Green, M.1    Carol, B.2    Behrendt, H.3
  • 71
    • 70449178060 scopus 로고
    • "Skin pH pattern in the newborn infant."
    • Behrendt H, Green M "Skin pH pattern in the newborn infant.". AMA J Dis Child 1958, 95(1, Part 1):35-41.
    • (1958) AMA J Dis Child , vol.95 , Issue.1 , pp. 35-41
    • Behrendt, H.1    Green, M.2
  • 72
    • 0002082240 scopus 로고
    • "Permeability of oral mucosa and skin with age."
    • CRC Press, Boca Raton, FL, C. Squier, M. Hill (Eds.)
    • Squier C, et al. "Permeability of oral mucosa and skin with age.". The Effect of Aging in Oral Mucosa and 1994, 91-98. CRC Press, Boca Raton, FL. C. Squier, M. Hill (Eds.).
    • (1994) The Effect of Aging in Oral Mucosa and , pp. 91-98
    • Squier, C.1
  • 73
    • 0018644413 scopus 로고
    • "Perspectives and problems in cutaneous gerontology."
    • Kligman AM "Perspectives and problems in cutaneous gerontology.". J Invest Dermatol 1979, 73(1):39-46.
    • (1979) J Invest Dermatol , vol.73 , Issue.1 , pp. 39-46
    • Kligman, A.M.1
  • 74
    • 0023789153 scopus 로고
    • "The water barrier function of the skin in relation to the water content of stratum corneum, pH and skin lipids. The effect of alkaline soap and syndet on dry skin in elderly, non-atopic patients."
    • Thune P, et al. "The water barrier function of the skin in relation to the water content of stratum corneum, pH and skin lipids. The effect of alkaline soap and syndet on dry skin in elderly, non-atopic patients.". Acta Derm Venereol 1988, 68(4):277-283.
    • (1988) Acta Derm Venereol , vol.68 , Issue.4 , pp. 277-283
    • Thune, P.1
  • 75
    • 0343473948 scopus 로고
    • "Functional characteristics of aged skin."
    • Tagami H "Functional characteristics of aged skin.". Acta Dermatol Kyoto Eng ed. 1972, 67:131.
    • (1972) Acta Dermatol Kyoto Eng ed. , vol.67 , pp. 131
    • Tagami, H.1
  • 76
    • 0024953967 scopus 로고
    • "The effect of aging on percutaneous absorption in man."
    • Roskos KV, Maibach HI, Guy RH "The effect of aging on percutaneous absorption in man.". J Pharmacokinet Biopharm 1989, 17(6):617-630.
    • (1989) J Pharmacokinet Biopharm , vol.17 , Issue.6 , pp. 617-630
    • Roskos, K.V.1    Maibach, H.I.2    Guy, R.H.3
  • 77
    • 1342272343 scopus 로고
    • "Percutaneous absorption of hydrocortisone-4-C14 in two human subjects."
    • Malkinson FD, Ferguson EH "Percutaneous absorption of hydrocortisone-4-C14 in two human subjects.". J Invest Dermatol 1955, 25(5):281-283.
    • (1955) J Invest Dermatol , vol.25 , Issue.5 , pp. 281-283
    • Malkinson, F.D.1    Ferguson, E.H.2
  • 78
    • 0003174411 scopus 로고
    • "Barriers to skin penetration."
    • Marzulli FN "Barriers to skin penetration.". J Invest Dermatol 1962, 39:387-393.
    • (1962) J Invest Dermatol , vol.39 , pp. 387-393
    • Marzulli, F.N.1
  • 80
    • 0037381857 scopus 로고    scopus 로고
    • "Age-specific skin blood flow responses to acute capsaicin."
    • Munce TA, Kenney WL "Age-specific skin blood flow responses to acute capsaicin.". J Gerontol A Biol Sci Med Sci 2003, 58(4):304-310.
    • (2003) J Gerontol A Biol Sci Med Sci , vol.58 , Issue.4 , pp. 304-310
    • Munce, T.A.1    Kenney, W.L.2
  • 81
    • 0026017328 scopus 로고
    • "Effect of low-concentration sodium lauryl sulfate on human vulvar and forearm skin. Age-related differences."
    • Elsner P, Wilhelm D, Maibach HI "Effect of low-concentration sodium lauryl sulfate on human vulvar and forearm skin. Age-related differences.". J Reprod Med 1991, 36(1):77-81.
    • (1991) J Reprod Med , vol.36 , Issue.1 , pp. 77-81
    • Elsner, P.1    Wilhelm, D.2    Maibach, H.I.3
  • 82
    • 0025230688 scopus 로고
    • "Age-related changes in skin blood flow at four anatomic sites of the body in males studied by xenon-133."
    • Tsuchida Y "Age-related changes in skin blood flow at four anatomic sites of the body in males studied by xenon-133.". Plast Reconstr Surg 1990, 85(4):556-561.
    • (1990) Plast Reconstr Surg , vol.85 , Issue.4 , pp. 556-561
    • Tsuchida, Y.1
  • 84
    • 0010113145 scopus 로고
    • "Cutaneous blood flow."
    • University of Tokyo Press, Japan, A. Kligman, Y. Takashe (Eds.)
    • Ishihara M, et al. "Cutaneous blood flow.". Cutaneous Aging 1988, University of Tokyo Press, Japan. A. Kligman, Y. Takashe (Eds.).
    • (1988) Cutaneous Aging
    • Ishihara, M.1
  • 86
    • 0020080377 scopus 로고
    • "Studies in cutaneous aging: II. The microvasculature."
    • Braverman IM, Fonferko E "Studies in cutaneous aging: II. The microvasculature.". J Invest Dermatol 1982, 78(5):444-448.
    • (1982) J Invest Dermatol , vol.78 , Issue.5 , pp. 444-448
    • Braverman, I.M.1    Fonferko, E.2
  • 87
    • 0002796716 scopus 로고
    • "Percutaneous absorption in aged skin."
    • Permagon Press, Oxford, W. Montagna (Ed.)
    • Christophers E, Kligman AM "Percutaneous absorption in aged skin.". Advances in the Biology of the 1964, 163. Permagon Press, Oxford. W. Montagna (Ed.).
    • (1964) Advances in the Biology of the , pp. 163
    • Christophers, E.1    Kligman, A.M.2
  • 88
    • 0035040246 scopus 로고    scopus 로고
    • "Age difference in simultaneous permeation and metabolism of ethyl nicotinate in rat skin."
    • Ngawhirunpat T, et al. "Age difference in simultaneous permeation and metabolism of ethyl nicotinate in rat skin.". Biol Pharm Bull 2001, 24(4):414-417.
    • (2001) Biol Pharm Bull , vol.24 , Issue.4 , pp. 414-417
    • Ngawhirunpat, T.1
  • 89
    • 0036725913 scopus 로고    scopus 로고
    • "Changes in electrophysiological properties of rat skin with age."
    • Ngawhirunpat T, et al. "Changes in electrophysiological properties of rat skin with age.". Biol Pharm Bull 2002, 25(9):1192-1196.
    • (2002) Biol Pharm Bull , vol.25 , Issue.9 , pp. 1192-1196
    • Ngawhirunpat, T.1
  • 90
    • 0008847601 scopus 로고
    • "Influence of age on percutaneous absorption of drug substances."
    • Marcel Dekker, New York, R. Bronaugh, H.I. Maibach (Eds.)
    • Behl C, Bellantone N, Flynn G "Influence of age on percutaneous absorption of drug substances.". Percutaneous Absorption: Mechanisms, Methodology, Drug Delivery 1985, 183. Marcel Dekker, New York. R. Bronaugh, H.I. Maibach (Eds.).
    • (1985) Percutaneous Absorption: Mechanisms, Methodology, Drug Delivery , pp. 183
    • Behl, C.1    Bellantone, N.2    Flynn, G.3
  • 91
    • 0035091269 scopus 로고    scopus 로고
    • "Age-related changes in skin permeability of hydrophilic and lipophilic compounds in rats."
    • Ngawhirunpat T, et al. "Age-related changes in skin permeability of hydrophilic and lipophilic compounds in rats.". Pharmazie 2001, 56(3):231-234.
    • (2001) Pharmazie , vol.56 , Issue.3 , pp. 231-234
    • Ngawhirunpat, T.1
  • 92
    • 0017646431 scopus 로고
    • "Percutaneous absorption of testosterone in the newborn rhesus monkey: comparison to the adult."
    • Wester RC, et al. "Percutaneous absorption of testosterone in the newborn rhesus monkey: comparison to the adult.". Pediatr Res 1977, 11(6):737-739.
    • (1977) Pediatr Res , vol.11 , Issue.6 , pp. 737-739
    • Wester, R.C.1
  • 93
    • 0035848413 scopus 로고    scopus 로고
    • "In vitro transdermal iontophoretic transport of timolol maleate: effect of age and species."
    • Kanikkannan N, Singh J, Ramarao P "In vitro transdermal iontophoretic transport of timolol maleate: effect of age and species.". J Control Release 2001, 71(1):99-105.
    • (2001) J Control Release , vol.71 , Issue.1 , pp. 99-105
    • Kanikkannan, N.1    Singh, J.2    Ramarao, P.3
  • 94
    • 0043051554 scopus 로고
    • "Transdermal drug delivery to the newborn infant."
    • Marcel Dekker, New York, J. Hadgraft, R.H. Guy (Eds.)
    • Evans N, Rutter N "Transdermal drug delivery to the newborn infant.". Trandermal Drug Delivery 1989, 155-176. Marcel Dekker, New York. J. Hadgraft, R.H. Guy (Eds.).
    • (1989) Trandermal Drug Delivery , pp. 155-176
    • Evans, N.1    Rutter, N.2
  • 95
    • 0020691287 scopus 로고
    • "Barrier properties of the newborn infant's skin."
    • Harpin VA, Rutter N "Barrier properties of the newborn infant's skin.". J Pediatr 1983, 102(3):419-425.
    • (1983) J Pediatr , vol.102 , Issue.3 , pp. 419-425
    • Harpin, V.A.1    Rutter, N.2
  • 96
    • 1842388417 scopus 로고
    • "In vitro permeability studies on the permeability of infant skin."
    • Marcel Dekker Inc, New York, R.L. Bronaugh, H.I. Maibach (Eds.)
    • Fisher LB "In vitro permeability studies on the permeability of infant skin.". Percutaneous Absorption: Mechanisms, Methodology, Drug Delivery 1985, 213-222. Marcel Dekker Inc, New York. R.L. Bronaugh, H.I. Maibach (Eds.).
    • (1985) Percutaneous Absorption: Mechanisms, Methodology, Drug Delivery , pp. 213-222
    • Fisher, L.B.1
  • 97
    • 0020042450 scopus 로고
    • "Outbreak of accidental hexachlorophene poisoning in France."
    • Martin-Bouyer G., et al. "Outbreak of accidental hexachlorophene poisoning in France.". Lancet 1982, 1(8263):91-95.
    • (1982) Lancet , vol.1 , Issue.8263 , pp. 91-95
    • Martin-Bouyer, G.1
  • 98
    • 0000835728 scopus 로고
    • "Cyanosis in premature infants due to aniline dye intoxication."
    • Kagan BM, et al. "Cyanosis in premature infants due to aniline dye intoxication.". The Journal of Pediatrics 1949, 34:574-578.
    • (1949) The Journal of Pediatrics , vol.34 , pp. 574-578
    • Kagan, B.M.1
  • 99
    • 0013953897 scopus 로고
    • "Percutaneous absorption of hydrocortisone in children."
    • Feinblatt BI, et al. "Percutaneous absorption of hydrocortisone in children.". Am J Dis Child 1966, 112(3):218-224.
    • (1966) Am J Dis Child , vol.112 , Issue.3 , pp. 218-224
    • Feinblatt, B.I.1
  • 100
    • 0017867069 scopus 로고
    • "Goitre and hypothyroidism in the newborn after cutaneous absorption of iodine."
    • Chabrolle JP, Rossier A "Goitre and hypothyroidism in the newborn after cutaneous absorption of iodine.". Arch Dis Child 1978, 53(6):495-498.
    • (1978) Arch Dis Child , vol.53 , Issue.6 , pp. 495-498
    • Chabrolle, J.P.1    Rossier, A.2
  • 101
    • 0019457861 scopus 로고
    • "Burn hazard of isopropyl alcohol in the neonate."
    • Schick JB, Milstein JM "Burn hazard of isopropyl alcohol in the neonate.". Pediatrics 1981, 68(4):587-588.
    • (1981) Pediatrics , vol.68 , Issue.4 , pp. 587-588
    • Schick, J.B.1    Milstein, J.M.2
  • 102
    • 0019940166 scopus 로고
    • "Percutaneous alcohol absorption and skin necrosis in a preterm infant."
    • Harpin V, Rutter N "Percutaneous alcohol absorption and skin necrosis in a preterm infant.". Arch Dis Child 1982, 57(6):477-479.
    • (1982) Arch Dis Child , vol.57 , Issue.6 , pp. 477-479
    • Harpin, V.1    Rutter, N.2
  • 103
    • 0028618675 scopus 로고
    • "Transdermal delivery and the premature neonate."
    • Barrett DA, Rutter N "Transdermal delivery and the premature neonate.". Crit Rev Ther Drug Carrier Syst 1994, 11(1):1-30.
    • (1994) Crit Rev Ther Drug Carrier Syst , vol.11 , Issue.1 , pp. 1-30
    • Barrett, D.A.1    Rutter, N.2
  • 104
    • 0019514580 scopus 로고
    • "Pharmacology and toxicology of infant skin."
    • West DP, Worobec S, Solomon LM "Pharmacology and toxicology of infant skin.". J Invest Dermatol 1981, 76(3):147-150.
    • (1981) J Invest Dermatol , vol.76 , Issue.3 , pp. 147-150
    • West, D.P.1    Worobec, S.2    Solomon, L.M.3
  • 105
    • 0025794237 scopus 로고
    • "Percutaneous caffeine application in the treatment of neonatal apnoea."
    • Amato M, Isenschmid M, Huppi P "Percutaneous caffeine application in the treatment of neonatal apnoea.". Eur J Pediatr 1991, 150(8):592-594.
    • (1991) Eur J Pediatr , vol.150 , Issue.8 , pp. 592-594
    • Amato, M.1    Isenschmid, M.2    Huppi, P.3
  • 106
    • 0021997455 scopus 로고
    • "Percutaneous administration of theophylline in the preterm infant."
    • Evans NJ, et al. "Percutaneous administration of theophylline in the preterm infant.". J Pediatr 1985, 107(2):307-311.
    • (1985) J Pediatr , vol.107 , Issue.2 , pp. 307-311
    • Evans, N.J.1
  • 107
    • 0028058895 scopus 로고
    • "Percutaneous lignocaine absorption in newborn infants."
    • Barrett DA, Rutter N "Percutaneous lignocaine absorption in newborn infants.". Arch Dis Child 1994, 71(2):F122-F124.
    • (1994) Arch Dis Child , vol.71 , Issue.2 , pp. F122-F124
    • Barrett, D.A.1    Rutter, N.2
  • 108
    • 33646529495 scopus 로고    scopus 로고
    • "Understanding skin penetration: computer aided modeling and data interpretation."
    • Degim T "Understanding skin penetration: computer aided modeling and data interpretation.". Current Computer-Aided Drug Design 2005, 1(1):11-19.
    • (2005) Current Computer-Aided Drug Design , vol.1 , Issue.1 , pp. 11-19
    • Degim, T.1


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