메뉴 건너뛰기




Volumn 43, Issue 2, 2015, Pages 169-175

In vitro and in vivo activity of hyperimmune globulin preparations against multiresistant nosocomial pathogens

Author keywords

Animal model; IgG; IgM; Immune globuline preparations; Nosocomial pathogens; Opsonic killing; Protective efficacy

Indexed keywords

IMMUNOGLOBULIN; IMMUNOGLOBULIN A; IMMUNOGLOBULIN M; PENTAGLOBULIN;

EID: 84940001993     PISSN: 03008126     EISSN: 14390973     Source Type: Journal    
DOI: 10.1007/s15010-014-0706-1     Document Type: Article
Times cited : (31)

References (29)
  • 1
    • 84977771623 scopus 로고    scopus 로고
    • Jul 3. pp. 1–114
    • Centers for Disease Control and Prevention CDC. Antibiotic resistance threats in the United States 2013 Internet www.cdc.gov 2013 cited 2014 Jul 3. pp. 1–114. Available from: http://www.cdc.gov/drugresistance/threat-report-2013/.
    • (2014) Available from:
  • 2
    • 36048966216 scopus 로고    scopus 로고
    • Cave enterococcum!
    • COI: 1:STN:280:DC%2BD2snlvVCjtQ%3D%3D, PID: 17918131
    • Huebner J, Arciola CR. Cave enterococcum! Int J Artif Organs. 2007;30:852–3.
    • (2007) Int J Artif Organs , vol.30 , pp. 852-853
    • Huebner, J.1    Arciola, C.R.2
  • 3
    • 30644471173 scopus 로고    scopus 로고
    • Implant infections due to enterococci: role of capsular polysaccharides and biofilm
    • COI: 1:CAS:528:DC%2BD28XhsFehtrY%3D, PID: 16353114
    • Fabretti F, Huebner J. Implant infections due to enterococci: role of capsular polysaccharides and biofilm. Int J Artif Organs. 2005;28:1079–90.
    • (2005) Int J Artif Organs , vol.28 , pp. 1079-1090
    • Fabretti, F.1    Huebner, J.2
  • 4
    • 0842281536 scopus 로고    scopus 로고
    • Enterococcal infections: host response, therapeutic, and prophylactic possibilities
    • COI: 1:CAS:528:DC%2BD2cXptVejug%3D%3D, PID: 15040934
    • Koch S, Hufnagel M, Theilacker C, Huebner J. Enterococcal infections: host response, therapeutic, and prophylactic possibilities. Vaccine. 2004;22:822–30.
    • (2004) Vaccine , vol.22 , pp. 822-830
    • Koch, S.1    Hufnagel, M.2    Theilacker, C.3    Huebner, J.4
  • 5
    • 57749107808 scopus 로고    scopus 로고
    • Bad bugs, no drugs: no ESKAPE! an update from the Infectious Diseases Society of America
    • PID: 19035777
    • Talbot GH, Bradley JS, Edwards JE, Rice LB, Spellberg B. Bad bugs, no drugs: no ESKAPE! an update from the Infectious Diseases Society of America. Clin Infect Dis. 2009;48:1–12.
    • (2009) Clin Infect Dis , vol.48 , pp. 1-12
    • Talbot, G.H.1    Bradley, J.S.2    Edwards, J.E.3    Rice, L.B.4    Spellberg, B.5
  • 6
    • 84908016514 scopus 로고    scopus 로고
    • Anti-infective monoclonals step in where antimicrobials fail
    • COI: 1:CAS:528:DC%2BC3sXhslCms7jK, PID: 24213755
    • Fox JL. Anti-infective monoclonals step in where antimicrobials fail. Nat Biotechnol. 2013;31:952–4.
    • (2013) Nat Biotechnol , vol.31 , pp. 952-954
    • Fox, J.L.1
  • 7
    • 0037075260 scopus 로고    scopus 로고
    • Use of a Staphylococcus aureus conjugate vaccine in patients receiving hemodialysis
    • PID: 11844850
    • Shinefield H, Black S, Fattom A, Horwith G, Rasgon S, Ordonez J, et al. Use of a Staphylococcus aureus conjugate vaccine in patients receiving hemodialysis. N Engl J Med. 2002;346:491–6.
    • (2002) N Engl J Med , vol.346 , pp. 491-496
    • Shinefield, H.1    Black, S.2    Fattom, A.3    Horwith, G.4    Rasgon, S.5    Ordonez, J.6
  • 8
    • 4043164158 scopus 로고    scopus 로고
    • Human blood IgM “memory” B cells are circulating splenic marginal zone B cells harboring a prediversified immunoglobulin repertoire
    • COI: 1:CAS:528:DC%2BD2cXhtVGltbzM, PID: 15191950
    • Weller S, Braun MC, Tan BK, Rosenwald A, Cordier C, Conley ME, et al. Human blood IgM “memory” B cells are circulating splenic marginal zone B cells harboring a prediversified immunoglobulin repertoire. Blood. 2004;104:3647–54.
    • (2004) Blood , vol.104 , pp. 3647-3654
    • Weller, S.1    Braun, M.C.2    Tan, B.K.3    Rosenwald, A.4    Cordier, C.5    Conley, M.E.6
  • 9
    • 33749266224 scopus 로고    scopus 로고
    • Opsonic antibodies to Enterococcus faecalis strain 12030 are directed against lipoteichoic acid
    • COI: 1:CAS:528:DC%2BD28XhtVGmu7fK, PID: 16988246
    • Theilacker C, Kaczynski Z, Kropec A, Fabretti F, Sange T, Holst O, et al. Opsonic antibodies to Enterococcus faecalis strain 12030 are directed against lipoteichoic acid. Infect Immun. 2006;74:5703–12.
    • (2006) Infect Immun , vol.74 , pp. 5703-5712
    • Theilacker, C.1    Kaczynski, Z.2    Kropec, A.3    Fabretti, F.4    Sange, T.5    Holst, O.6
  • 10
    • 60349126579 scopus 로고    scopus 로고
    • Glycolipids are involved in biofilm accumulation and prolonged bacteraemia in Enterococcus faecalis
    • COI: 1:CAS:528:DC%2BD1MXivFaqurY%3D, PID: 19170884
    • Theilacker C, Sanchez-Carballo P, Toma I, Fabretti F, Sava I, Kropec A, et al. Glycolipids are involved in biofilm accumulation and prolonged bacteraemia in Enterococcus faecalis. Mol Microbiol. 2009;71:1055–69.
    • (2009) Mol Microbiol , vol.71 , pp. 1055-1069
    • Theilacker, C.1    Sanchez-Carballo, P.2    Toma, I.3    Fabretti, F.4    Sava, I.5    Kropec, A.6
  • 11
    • 1142309464 scopus 로고    scopus 로고
    • A putative sugar-binding transcriptional regulator in a novel gene locus in Enterococcus faecalis contributes to production of biofilm and prolonged bacteremia in mice
    • COI: 1:CAS:528:DC%2BD2cXhvFSgtbo%3D, PID: 14745699
    • Hufnagel M, Koch S, Creti R, Baldassarri L, Huebner J. A putative sugar-binding transcriptional regulator in a novel gene locus in Enterococcus faecalis contributes to production of biofilm and prolonged bacteremia in mice. J Infect Dis. 2004;189:420–30.
    • (2004) J Infect Dis , vol.189 , pp. 420-430
    • Hufnagel, M.1    Koch, S.2    Creti, R.3    Baldassarri, L.4    Huebner, J.5
  • 12
    • 84858224547 scopus 로고    scopus 로고
    • Protection against Staphylococcus aureus by antibody to the polyglycerolphosphate backbone of heterologous lipoteichoic acid
    • COI: 1:CAS:528:DC%2BC38XktVGmsb4%3D, PID: 22362863
    • Theilacker C, Kropec A, Hammer F, Sava I, Wobser D, Sakinc T, et al. Protection against Staphylococcus aureus by antibody to the polyglycerolphosphate backbone of heterologous lipoteichoic acid. J Infect Dis. 2012;205:1076–85.
    • (2012) J Infect Dis , vol.205 , pp. 1076-1085
    • Theilacker, C.1    Kropec, A.2    Hammer, F.3    Sava, I.4    Wobser, D.5    Sakinc, T.6
  • 13
    • 79952790266 scopus 로고    scopus 로고
    • Serodiversity of opsonic antibodies against Enterococcus faecalis—glycans of the cell wall revisited
    • COI: 1:CAS:528:DC%2BC3MXkt1SlsLc%3D, PID: 21437253
    • Theilacker C, Kaczynski Z, Kropec A, Sava I, Ye L, Bychowska A, et al. Serodiversity of opsonic antibodies against Enterococcus faecalis—glycans of the cell wall revisited. PLoS One. 2011;6:e17839.
    • (2011) PLoS One , vol.6 , pp. 17839
    • Theilacker, C.1    Kaczynski, Z.2    Kropec, A.3    Sava, I.4    Ye, L.5    Bychowska, A.6
  • 14
    • 0033052677 scopus 로고    scopus 로고
    • Isolation and chemical characterization of a capsular polysaccharide antigen shared by clinical isolates of Enterococcus faecalis and vancomycin-resistant Enterococcus faecium
    • COI: 1:CAS:528:DyaK1MXhsFemtLw%3D, PID: 10024563
    • Huebner J, Wang Y, Krueger WA, Madoff LC, Martirosian G, Boisot S, et al. Isolation and chemical characterization of a capsular polysaccharide antigen shared by clinical isolates of Enterococcus faecalis and vancomycin-resistant Enterococcus faecium. Infect Immun. 1999;67:1213–9.
    • (1999) Infect Immun , vol.67 , pp. 1213-1219
    • Huebner, J.1    Wang, Y.2    Krueger, W.A.3    Madoff, L.C.4    Martirosian, G.5    Boisot, S.6
  • 15
    • 67650528820 scopus 로고    scopus 로고
    • Novel interactions of glycosaminoglycans and bacterial glycolipids mediate binding of enterococci to human cells
    • COI: 1:CAS:528:DC%2BD1MXnslegtL8%3D, PID: 19395379
    • Sava IG, Zhang F, Toma I, Theilacker C, Li B, Baumert TF, et al. Novel interactions of glycosaminoglycans and bacterial glycolipids mediate binding of enterococci to human cells. J Biol Chem. 2009;284:18194–201.
    • (2009) J Biol Chem , vol.284 , pp. 18194-18201
    • Sava, I.G.1    Zhang, F.2    Toma, I.3    Theilacker, C.4    Li, B.5    Baumert, T.F.6
  • 16
    • 82555191256 scopus 로고    scopus 로고
    • Identification of SagA as a novel vaccine target for the prevention of Enterococcus faecium infections
    • COI: 1:CAS:528:DC%2BC3MXhs1GqtLjF, PID: 21903755
    • Kropec A, Sava IG, Vonend C, Sakinc T, Grohmann E, Huebner J. Identification of SagA as a novel vaccine target for the prevention of Enterococcus faecium infections. Microbiology. 2011;157:3429–34.
    • (2011) Microbiology , vol.157 , pp. 3429-3434
    • Kropec, A.1    Sava, I.G.2    Vonend, C.3    Sakinc, T.4    Grohmann, E.5    Huebner, J.6
  • 17
    • 84866679186 scopus 로고    scopus 로고
    • Andrews SF. Tools to therapeutically harness the human antibody response
    • Wilson PC, Andrews SF. Tools to therapeutically harness the human antibody response. Nat Rev Immunol. Nature Publishing Group; 2012;12:709–19.
    • (2012) Nat Rev Immunol. Nature Publishing Group , vol.12 , pp. 709-719
    • Wilson, P.C.1
  • 18
    • 84906791488 scopus 로고    scopus 로고
    • Detection of opsonic antibodies against Enterococcus faecalis cell wall carbohydrates in immune globulin preparations
    • Hufnagel M, Sixel K, Hammer F, Kropec A, Sava IG, Theilacker C, et al. Detection of opsonic antibodies against Enterococcus faecalis cell wall carbohydrates in immune globulin preparations. Infection. Springer Berlin Heidelberg; 2014;42:749–55.
    • (2014) Infection. Springer Berlin Heidelberg , vol.42 , pp. 749-755
    • Hufnagel, M.1    Sixel, K.2    Hammer, F.3    Kropec, A.4    Sava, I.G.5    Theilacker, C.6
  • 19
    • 84891643048 scopus 로고    scopus 로고
    • Ohlsson A, Lacy JB. Intravenous immunoglobulin for preventing infection in preterm and/or low birth weight infants. In: Ohlsson A, editor. Cochrane database of systematic reviews (Online). Chichester: John Wiley & Sons, Ltd; 2013;7:CD000361
    • Ohlsson A, Lacy JB. Intravenous immunoglobulin for preventing infection in preterm and/or low birth weight infants. In: Ohlsson A, editor. Cochrane database of systematic reviews (Online). Chichester: John Wiley & Sons, Ltd; 2013;7:CD000361.
  • 20
    • 84858615495 scopus 로고    scopus 로고
    • Relationship between the timing of administration of IgM and IgA enriched immunoglobulins in patients with severe sepsis and septic shock and the outcome: a retrospective analysis
    • COI: 1:CAS:528:DC%2BC38XktlKrurY%3D, PID: 21737236
    • Berlot G, Vassallo MC, Busetto N, Bianchi M, Zornada F, Rosato I, et al. Relationship between the timing of administration of IgM and IgA enriched immunoglobulins in patients with severe sepsis and septic shock and the outcome: a retrospective analysis. J Crit Care. 2012;27:167–71.
    • (2012) J Crit Care , vol.27 , pp. 167-171
    • Berlot, G.1    Vassallo, M.C.2    Busetto, N.3    Bianchi, M.4    Zornada, F.5    Rosato, I.6
  • 21
    • 84873444818 scopus 로고    scopus 로고
    • Protective roles of natural IgM antibodies
    • PID: 22566947
    • Grönwall C, Vas J, Silverman GJ. Protective roles of natural IgM antibodies. Front Immunol. 2012;3:66.
    • (2012) Front Immunol , vol.3 , pp. 66
    • Grönwall, C.1    Vas, J.2    Silverman, G.J.3
  • 22
    • 0028938186 scopus 로고
    • T cell-independent antigens type 2
    • COI: 1:CAS:528:DyaK2MXltFamu74%3D, PID: 7612238
    • Mond JJ, Lees A, Snapper CM. T cell-independent antigens type 2. Annu Rev Immunol. 1995;13:655–92.
    • (1995) Annu Rev Immunol , vol.13 , pp. 655-692
    • Mond, J.J.1    Lees, A.2    Snapper, C.M.3
  • 23
    • 27144436171 scopus 로고    scopus 로고
    • Cost-effectiveness of immunoglobulin M-enriched immunoglobulin (Pentaglobin) in the treatment of severe sepsis and septic shock
    • PID: 16253792
    • Neilson AR, Burchardi H, Schneider H. Cost-effectiveness of immunoglobulin M-enriched immunoglobulin (Pentaglobin) in the treatment of severe sepsis and septic shock. J Crit Care. 2005;20:239–49.
    • (2005) J Crit Care , vol.20 , pp. 239-249
    • Neilson, A.R.1    Burchardi, H.2    Schneider, H.3
  • 24
    • 0036336714 scopus 로고    scopus 로고
    • The effects of IgM-enriched immunoglobulin preparations in patients with severe sepsis [ISRCTN28863830]
    • PID: 12225613
    • Tugrul S, Ozcan PE, Akinci O, Seyhun Y, Cagatay A, Cakar N, et al. The effects of IgM-enriched immunoglobulin preparations in patients with severe sepsis [ISRCTN28863830]. Crit Care. 2002;6:357–62.
    • (2002) Crit Care , vol.6 , pp. 357-362
    • Tugrul, S.1    Ozcan, P.E.2    Akinci, O.3    Seyhun, Y.4    Cagatay, A.5    Cakar, N.6
  • 25
    • 84875671259 scopus 로고    scopus 로고
    • Polyvalent immunoglobulin significantly attenuated the formation of IL-1β in Escherichia coli-induced sepsis in pigs
    • Barratt-Due A, Sokolov A, Gustavsen A, Hellerud BC, Egge K, Pischke SE, et al. Polyvalent immunoglobulin significantly attenuated the formation of IL-1β in Escherichia coli-induced sepsis in pigs. Immunobiology. Elsevier GmbH; 2013;218:683–9.
    • (2013) Immunobiology. Elsevier GmbH , vol.218 , pp. 683-689
    • Barratt-Due, A.1    Sokolov, A.2    Gustavsen, A.3    Hellerud, B.C.4    Egge, K.5    Pischke, S.E.6
  • 27
    • 36549020645 scopus 로고    scopus 로고
    • Enterococcal surface protein Esp is important for biofilm formation of Enterococcus faecium E1162
    • COI: 1:CAS:528:DC%2BD2sXhtlyht7vP, PID: 17827282
    • Heikens E, Bonten MJM, Willems RJL. Enterococcal surface protein Esp is important for biofilm formation of Enterococcus faecium E1162. J Bacteriol. 2007;189:8233–40.
    • (2007) J Bacteriol , vol.189 , pp. 8233-8240
    • Heikens, E.1    Bonten, M.J.M.2    Willems, R.J.L.3
  • 28
    • 77956356704 scopus 로고    scopus 로고
    • agr-Dependent interactions of Staphylococcus aureus USA300 with human polymorphonuclear neutrophils
    • COI: 1:CAS:528:DC%2BC3cXht12lurzE, PID: 20829608
    • Pang YY, Schwartz J, Thoendel M, Ackermann LW, Horswill AR, Nauseef WM. agr-Dependent interactions of Staphylococcus aureus USA300 with human polymorphonuclear neutrophils. J Innate Immun. 2010;2:546–59.
    • (2010) J Innate Immun. , vol.2 , pp. 546-559
    • Pang, Y.Y.1    Schwartz, J.2    Thoendel, M.3    Ackermann, L.W.4    Horswill, A.R.5    Nauseef, W.M.6
  • 29
    • 84864462085 scopus 로고    scopus 로고
    • In vitro susceptibilities and molecular analysis of vancomycin-intermediate and vancomycin-resistant Staphylococcus aureus isolates
    • COI: 1:CAS:528:DC%2BC38XhtFagu7rJ, PID: 22615331
    • Saravolatz LD, Pawlak J, Johnson LB. In vitro susceptibilities and molecular analysis of vancomycin-intermediate and vancomycin-resistant Staphylococcus aureus isolates. Clin Infect Dis. 2012;55:582–6.
    • (2012) Clin Infect Dis , vol.55 , pp. 582-586
    • Saravolatz, L.D.1    Pawlak, J.2    Johnson, L.B.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.