25I-NBOMe related death in Australia: A case report

Forensic Science International

Volumn 249, Issue , 2015, Pages e15-e18

  Kueppers, Victoria B ^a   Cooke, Clive T ^a,b  

^a PATHWEST LABORATORY MEDICINE   (Australia)

^b NONE   (Australia)

Author keywords

25I NBOMe; Fatality; NBOMe; NPS

Indexed keywords

2-(4-IODO-2,5-DIMETHOXYPHENYL)-N-(2-METHOXYBENZYL)ETHANAMINE; DESIGNER DRUG; HOMOVERATRYLAMINE; PSYCHEDELIC AGENT;

ADULT; ANALOGS AND DERIVATIVES; AUSTRALIA; CASE REPORT; FATALITY; FEMALE; HUMAN; YOUNG ADULT;

ADULT; AUSTRALIA; DESIGNER DRUGS; DIMETHOXYPHENYLETHYLAMINE; FATAL OUTCOME; FEMALE; HALLUCINOGENS; HUMANS; YOUNG ADULT;

EID: 84940000773     PISSN: 03790738     EISSN: 18726283     Source Type: Journal    
DOI: 10.1016/j.forsciint.2015.02.010     Document Type: Article

References (25)

1. United Nations Office on Drugs and Crime (UNODC) World Drug Report 2013.
2. Elliott S., Evans J. A 3-year review of new psychoactive substances in casework. Forensic Sci. Int. 2014, 243:55-60.
3. World Health Organisation (WHO) Expert Committee on Drug Dependence, 25I-NBOMe Critical Review Report; 36th Meeting 2014.
4. Walterscheid J.P., Garrett G.T., Lopez A.E., Gonsoulin M.L., Chen H., Sanchez L.A. Pathological findings in 2 cases of fatal 25I-NBOMe toxicity. Am. J. Forensic Med. Pathol. 2014, 35(1):20-25.
5. United Nations Office on Drugs and Crime (UNODC) Global SMART Programme, The Challenge of New Psychoactive Substances 2013, http://www.unodc.org/documents/scientific/NPS_2013_SMART.pdf.
6. Advisory Council on the Misuse of Drugs (ACMD) 'NBOMe' Compounds: A Review of the Evidence of Use and Harm 2013 November, London, UK.
7. Deadly Chemical NBOM-e Blamed for Drug Deaths, published online August 7th, 2013. Accessed 14/10/2014. http://www.abc.net.au/7.30/content/2013/s3820575.htm.
8. www.smh.com.au/action/printArticle?id=4470300, Cheap High: I Remember Nothing But Death, published online June 7th, 2013. Accessed 14/10/2014.
9. www.news.com.au/national/south-australia/new-hallucinogenic-drug-25b-nbome-and-25i-nbome-led-to-south-australian-mans-bizarre-death/story-fndo4dzn-1226472672220, New Hallucinogenic Drug 25B-NBOMe and 25I-NBOMe Led to South Australian Man's Bizarre Death, published online September 12th, 2012. Accessed 10/10/2014.
10. www.druginfo.adf.org.au/nbomes/drug-information/drug-facts/nbomes/print, NBOMe facts. Accessed 10/10/2014.
11. Poklis J.L., Devers K.G., Arbefeville E.F., Pearson J.M., Houston E., Poklis A. Postmortem detection of 25I-NBOMe [2-(4-iodo-2,5-dimethoxyphenyl)-N-[(2-methoxyphenyl)methyl]ethenamine] in fluids and tissues determined by high performance liquid chromatography with tandem mass spectrometry from a traumatic death. Forensic Sci Int. 2014, 234:e14-e20.
12. Rose S.R., Poklis J.L., Poklis A. A case of 25I-NBOMe (25-I) intoxication: a new potent 5-HT2A agonist designer drug. Clin. Toxicol. 2013, 51:174-177.
13. Poklis J.L., Charles J., Wolf C.E., Poklis A. High-performance liquid chromatography tandem mass spectrometry method for the determination of 2CC-NBOMe and 25I-NBOMe in human serum. Biomed. Chrom. 2013, 27:1794-1800.
14. Stellpflug S.J., Kealey S.E., Hegarty C.B., Janis G.C. 2-(4-Iodo-2,5-dimethoxyphenyl)-N-[(2-methoxyphenyl)methyl]ethanamine (25I-NBOMe): clinical case with unique confirmatory testing. J. Med. Toxicol. 2014, 10:45-50.
15. Kelly A., Eisenga B., Riley B., Judge B. Case series of 25I-NBOMe exposures with laboratory confirmation. Clin. Toxicol. 2012, 50(7):702. (abstract).
16. Logan B.K., Fligner C.L., Haddix T. Cause and manner of death in fatalities involving methamphetamine. J. Forensic Sci. 1998, 43:28-34.
17. National Highway Traffic Safety Administration, Drugs and Human Performance Fact Sheet, . http://www.nhtsa.dot.gov/people/injury/research/job185drugs/methamphetamine.htm.
18. Shulgin A., Shulgin A. PiHKAL-A Chemical Love Story 1990, Transform Press, Berkeley. first ed.
19. Musselman M.E., Hampton J.P. Not for human consumption: a review of emerging designer drugs. Pharmacotherapy 2014, 34(7):745-757.
20. Meyer M.R., Maurer H.H. Metabolism of designer drugs of abuse: an updated review. Curr. Drug Metab. 2010, 11:468-482.
21. Schlatter E., Logan B.K. Emerging Designer Drug Monograph 25I-NBOMe, SOFT Designer Drug Committee Monographs vers. 1. 1 2013.
22. www.erowid.org.
23. Hill S.L., Doris T., Gurung S., Katebe S., Lomas A., Dunn M., Blain P., Thomas S.H.L. Severe clinical toxicity associated with analytically confirmed recreational use of 25I-NBOMe: case series. Clin. Toxicol. 2013, 51:487-492.
24. United Nations Office on Drugs and Crime (UNODC) World Drug Report 2014, (United Nations publication, Sales No. E.14.XL.7).
25. Intergovernmental Committee on Drugs (IGCD) Framework for a National Response to New Psychoactive Substances 2014 July, (Accessed via www.nationaldrugstrategy.gov.au on 10/10/2014).