Is gentamicin affecting the neuromuscular system of critically ill patients?

Intensive Care Medicine

Volumn 41, Issue 4, 2015, Pages 727-728

  Wieske, Luuk ^a   van Hest, Reinier M ^a   Witteveen, Esther ^a   Verhamme, Camiel ^a   Schultz, Marcus J ^a   van Schaik, Ivo N ^a   Horn, Janneke ^a  

^a ACADEMIC MEDICAL CENTER   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIINFECTIVE AGENT; GENTAMICIN;

CHEMICALLY INDUCED; CRITICAL ILLNESS; HUMAN; INTENSIVE CARE UNIT; MUSCLE WEAKNESS;

ANTI-BACTERIAL AGENTS; CRITICAL ILLNESS; GENTAMICINS; HUMANS; INTENSIVE CARE UNITS; MUSCLE WEAKNESS;

EID: 84939976370     PISSN: 03424642     EISSN: 14321238     Source Type: Journal    
DOI: 10.1007/s00134-015-3731-3     Document Type: Letter

References (5)

1. Latronico N, Bolton CF (2011) Critical illness polyneuropathy and myopathy: a major cause of muscle weakness and paralysis. Lancet Neurol 10:931–941
2. Wieske L, Witteveen E, Verhamme C et al (2014) Early prediction of intensive care unit-acquired weakness using easily available parameters: a prospective observational study. PLoS One 9:e111259
3. Grill MF, Maganti RK (2011) Neurotoxic effects associated with antibiotic use: management considerations. Br J Clin Pharmacol 72:381–393
4. Schlesinger F, Krampfl K, Haeseler G et al (2004) Competitive and open channel block of recombinant nAChR channels by different antibiotics. Neuromuscul Disord 14:307–312
5. Lee S-I, Lee JH, Park SY, Park JW (2013) Do bupivacaine, clindamycin, and gentamicin at their clinical concentrations enhance rocuronium-induced neuromuscular block? Korean J Anesthesiol 64:346