메뉴 건너뛰기




Volumn 30, Issue 5, 2015, Pages 775-781

Eculizumab hepatotoxicity in pediatric aHUS

Author keywords

Atypical hemolytic uremic syndrome; Complement; Eculizumab; Hepatotoxicity; Thrombotic microangiopathy; Transaminitis

Indexed keywords

ECULIZUMAB; MONOCLONAL ANTIBODY;

EID: 84939974908     PISSN: 0931041X     EISSN: 1432198X     Source Type: Journal    
DOI: 10.1007/s00467-014-2990-5     Document Type: Article
Times cited : (38)

References (37)
  • 4
    • 84872336333 scopus 로고    scopus 로고
    • Treatment of atypical hemolytic uremic syndrome and thrombotic microangiopathies: a focus on eculizumab
    • COI: 1:CAS:528:DC%2BC38Xhs1Gksb7F, PID: 23141475
    • Schmidtko J, Peine S, El-Housseini Y, Pascual M, Meier P (2013) Treatment of atypical hemolytic uremic syndrome and thrombotic microangiopathies: a focus on eculizumab. Am J Kidney Dis 61:289–299
    • (2013) Am J Kidney Dis , vol.61 , pp. 289-299
    • Schmidtko, J.1    Peine, S.2    El-Housseini, Y.3    Pascual, M.4    Meier, P.5
  • 5
  • 6
    • 59449088846 scopus 로고    scopus 로고
    • Eculizumab for congenital atypical hemolytic-uremic syndrome
    • COI: 1:CAS:528:DC%2BD1MXht1aiurw%3D, PID: 19179329
    • Gruppo RA, Rother RP (2009) Eculizumab for congenital atypical hemolytic-uremic syndrome. N Engl J Med 360:544–546
    • (2009) N Engl J Med , vol.360 , pp. 544-546
    • Gruppo, R.A.1    Rother, R.P.2
  • 9
    • 84860244540 scopus 로고    scopus 로고
    • Gonococcal septic shock associated with eculizumab treatment
    • PID: 22511000
    • Gleesing J, Chiwane S, Rongkavilit C (2012) Gonococcal septic shock associated with eculizumab treatment. Pediatr Infect Dis J 31:543
    • (2012) Pediatr Infect Dis J , vol.31 , pp. 543
    • Gleesing, J.1    Chiwane, S.2    Rongkavilit, C.3
  • 10
    • 77951563820 scopus 로고    scopus 로고
    • Photodermatosis associated with eculizumab (Soliris): a novel monoclonal antibody directed against the complement protein C5
    • PID: 20232400
    • Balagula Y, Newman SB, Lacouture ME (2010) Photodermatosis associated with eculizumab (Soliris): a novel monoclonal antibody directed against the complement protein C5. Am J Hematol 85:392–393
    • (2010) Am J Hematol , vol.85 , pp. 392-393
    • Balagula, Y.1    Newman, S.B.2    Lacouture, M.E.3
  • 12
    • 55549093797 scopus 로고    scopus 로고
    • Life-threatening desquamating rash and hyperammonemia following administration of eculizumab for paroxysmal nocturnal hemoglobinuria
    • PID: 18756538
    • Knoll BM, Letendre L, Steensma DP (2008) Life-threatening desquamating rash and hyperammonemia following administration of eculizumab for paroxysmal nocturnal hemoglobinuria. Am J Hematol 83:881–883
    • (2008) Am J Hematol , vol.83 , pp. 881-883
    • Knoll, B.M.1    Letendre, L.2    Steensma, D.P.3
  • 14
    • 84868259701 scopus 로고    scopus 로고
    • Tocilizumab for the treatment of large-vessel vasculitis (giant cell arteritis, Takayasu arteritis) and polymyalgia rheumatica
    • COI: 1:CAS:528:DC%2BC3sXjtleqsw%3D%3D
    • Unizony S, Arias-Urdaneta L, Miloslavsky E, Arvikar S, Khosroshahi A, Keroack B, Stone JR, Stone JH (2012) Tocilizumab for the treatment of large-vessel vasculitis (giant cell arteritis, Takayasu arteritis) and polymyalgia rheumatica. Arthritis Care Res 64:1720–1729
    • (2012) Arthritis Care Res , vol.64 , pp. 1720-1729
    • Unizony, S.1    Arias-Urdaneta, L.2    Miloslavsky, E.3    Arvikar, S.4    Khosroshahi, A.5    Keroack, B.6    Stone, J.R.7    Stone, J.H.8
  • 15
    • 84859624578 scopus 로고    scopus 로고
    • Systematic review of tocilizumab for rheumatoid arthritis: a new biologic agent targeting the interleukin-6 receptor
    • COI: 1:CAS:528:DC%2BC38XlvFGitL4%3D, PID: 22444783
    • Navarro-Millan I, Singh JA, Curtis JR (2012) Systematic review of tocilizumab for rheumatoid arthritis: a new biologic agent targeting the interleukin-6 receptor. Clin Ther 34:788–802
    • (2012) Clin Ther , vol.34 , pp. 788-802
    • Navarro-Millan, I.1    Singh, J.A.2    Curtis, J.R.3
  • 16
    • 78650339895 scopus 로고    scopus 로고
    • Phase I clinical trial of the chimeric anti-mesothelin monoclonal antibody MORAb-009 in patients with mesothelin-expressing cancers
    • COI: 1:CAS:528:DC%2BC3cXhsFOjtr%2FN, PID: 21037025
    • Hassan R, Cohen SJ, Phillips M, Pastan I, Sharon E, Kelly RJ, Schweizer C, Weil S, Laheru D (2010) Phase I clinical trial of the chimeric anti-mesothelin monoclonal antibody MORAb-009 in patients with mesothelin-expressing cancers. Clin Cancer Res 16:6132–6138
    • (2010) Clin Cancer Res , vol.16 , pp. 6132-6138
    • Hassan, R.1    Cohen, S.J.2    Phillips, M.3    Pastan, I.4    Sharon, E.5    Kelly, R.J.6    Schweizer, C.7    Weil, S.8    Laheru, D.9
  • 17
    • 76749097152 scopus 로고    scopus 로고
    • Phase 1 study of combination treatment with PTK 787/ZK 222584 and cetuximab for patients with advanced solid tumors: safety, pharmacokinetics, pharmacodynamics analysis
    • COI: 1:CAS:528:DC%2BC3cXhsFGrs7Y%3D, PID: 20126478
    • Langenberg MH, Witteveen PO, Lankheet NA, Roodhart JM, Rosing H, van den Heuvel IJ, Beijnen JH, Voest EE (2010) Phase 1 study of combination treatment with PTK 787/ZK 222584 and cetuximab for patients with advanced solid tumors: safety, pharmacokinetics, pharmacodynamics analysis. Neoplasia 12:206–213
    • (2010) Neoplasia , vol.12 , pp. 206-213
    • Langenberg, M.H.1    Witteveen, P.O.2    Lankheet, N.A.3    Roodhart, J.M.4    Rosing, H.5    van den Heuvel, I.J.6    Beijnen, J.H.7    Voest, E.E.8
  • 18
    • 76349085626 scopus 로고    scopus 로고
    • Phase II trial of mapatumumab, a fully human agonistic monoclonal antibody that targets and activates the tumour necrosis factor apoptosis-inducing ligand receptor-1 (TRAIL-R1), in patients with refractory colorectal cancer
    • COI: 1:CAS:528:DC%2BC3cXhsVSrs7s%3D, PID: 20068564
    • Trarbach T, Moehler M, Heinemann V, Kohne CH, Przyborek M, Schulz C, Sneller V, Gallant G, Kanzler S (2010) Phase II trial of mapatumumab, a fully human agonistic monoclonal antibody that targets and activates the tumour necrosis factor apoptosis-inducing ligand receptor-1 (TRAIL-R1), in patients with refractory colorectal cancer. Br J Cancer 102:506–512
    • (2010) Br J Cancer , vol.102 , pp. 506-512
    • Trarbach, T.1    Moehler, M.2    Heinemann, V.3    Kohne, C.H.4    Przyborek, M.5    Schulz, C.6    Sneller, V.7    Gallant, G.8    Kanzler, S.9
  • 19
    • 33750325782 scopus 로고    scopus 로고
    • Onset of liver damage after a single administration of infliximab in a patient with refractory ulcerative colitis
    • Ierardi E, Valle ND, Nacchiero MC, De Francesco V, Stoppino G, Panella C (2006) Onset of liver damage after a single administration of infliximab in a patient with refractory ulcerative colitis. Clin Drug Invest 26:673–676
    • (2006) Clin Drug Invest , vol.26 , pp. 673-676
    • Ierardi, E.1    Valle, N.D.2    Nacchiero, M.C.3    De Francesco, V.4    Stoppino, G.5    Panella, C.6
  • 20
    • 0035160406 scopus 로고    scopus 로고
    • Infliximab-associated reversible cholestatic liver disease
    • COI: 1:STN:280:DC%2BD3M%2FptlKjsA%3D%3D, PID: 11155419
    • Menghini VV, Arora AS (2001) Infliximab-associated reversible cholestatic liver disease. Mayo Clin Proc 76:84–86
    • (2001) Mayo Clin Proc , vol.76 , pp. 84-86
    • Menghini, V.V.1    Arora, A.S.2
  • 21
    • 0034893164 scopus 로고    scopus 로고
    • Hepatitis with interface inflammation and IgG, IgM, and IgA anti-double-stranded DNA antibodies following infliximab therapy: comment on the article by Charles et al
    • COI: 1:STN:280:DC%2BD3MvmtlGmtQ%3D%3D, PID: 11508453
    • Saleem G, Li SC, MacPherson BR, Cooper SM (2001) Hepatitis with interface inflammation and IgG, IgM, and IgA anti-double-stranded DNA antibodies following infliximab therapy: comment on the article by Charles et al. Arthritis Rheum 44:1966–1968
    • (2001) Arthritis Rheum , vol.44 , pp. 1966-1968
    • Saleem, G.1    Li, S.C.2    MacPherson, B.R.3    Cooper, S.M.4
  • 25
    • 38449123106 scopus 로고    scopus 로고
    • Autoimmune hepatitis following infliximab therapy for ankylosing spondylitis
    • PID: 17979620
    • Ozorio G, McGarity B, Bak H, Jordan AS, Lau H, Marshall C (2007) Autoimmune hepatitis following infliximab therapy for ankylosing spondylitis. Med J Aust 187:524–526
    • (2007) Med J Aust , vol.187 , pp. 524-526
    • Ozorio, G.1    McGarity, B.2    Bak, H.3    Jordan, A.S.4    Lau, H.5    Marshall, C.6
  • 26
    • 35948959015 scopus 로고    scopus 로고
    • Discovery and development of the complement inhibitor eculizumab for the treatment of paroxysmal nocturnal hemoglobinuria
    • COI: 1:CAS:528:DC%2BD2sXht1Oru7zE, PID: 17989688
    • Rother RP, Rollins SA, Mojcik CF, Brodsky RA, Bell L (2007) Discovery and development of the complement inhibitor eculizumab for the treatment of paroxysmal nocturnal hemoglobinuria. Nat Biotechnol 25:1256–1264
    • (2007) Nat Biotechnol , vol.25 , pp. 1256-1264
    • Rother, R.P.1    Rollins, S.A.2    Mojcik, C.F.3    Brodsky, R.A.4    Bell, L.5
  • 27
    • 84904503391 scopus 로고    scopus 로고
    • Eculizumab in paroxysmal nocturnal hemoglobinuria with Budd-Chiari syndrome progressing despite anticoagulation
    • COI: 1:CAS:528:DC%2BC38XhvVWnurbL, PID: 23210433
    • Brodsky A, Mazzocchi O, Sanchez F, Khursigara G, Malhotra S, Volpacchio M (2012) Eculizumab in paroxysmal nocturnal hemoglobinuria with Budd-Chiari syndrome progressing despite anticoagulation. Exp Hematol Oncol 1:26
    • (2012) Exp Hematol Oncol , vol.1 , pp. 26
    • Brodsky, A.1    Mazzocchi, O.2    Sanchez, F.3    Khursigara, G.4    Malhotra, S.5    Volpacchio, M.6
  • 31
    • 51649119906 scopus 로고    scopus 로고
    • Impaired CD163-mediated hemoglobin-scavenging and severe toxic symptoms in patients treated with gemtuzumab ozogamicin
    • COI: 1:CAS:528:DC%2BD1cXpvVOkurw%3D, PID: 18550848
    • Maniecki MB, Hasle H, Friis-Hansen L, Lausen B, Nielsen OJ, Bendix K, Moestrup SK, Moller HJ (2008) Impaired CD163-mediated hemoglobin-scavenging and severe toxic symptoms in patients treated with gemtuzumab ozogamicin. Blood 112:1510–1514
    • (2008) Blood , vol.112 , pp. 1510-1514
    • Maniecki, M.B.1    Hasle, H.2    Friis-Hansen, L.3    Lausen, B.4    Nielsen, O.J.5    Bendix, K.6    Moestrup, S.K.7    Moller, H.J.8
  • 32
    • 0035865055 scopus 로고    scopus 로고
    • A novel role of complement: mice deficient in the fifth component of complement (C5) exhibit impaired liver regeneration
    • COI: 1:CAS:528:DC%2BD3MXht1Giuro%3D, PID: 11160308
    • Mastellos D, Papadimitriou JC, Franchini S, Tsonis PA, Lambris JD (2001) A novel role of complement: mice deficient in the fifth component of complement (C5) exhibit impaired liver regeneration. J Immunol 166:2479–2486
    • (2001) J Immunol , vol.166 , pp. 2479-2486
    • Mastellos, D.1    Papadimitriou, J.C.2    Franchini, S.3    Tsonis, P.A.4    Lambris, J.D.5
  • 33
    • 0035094838 scopus 로고    scopus 로고
    • Functions of anaphylatoxin C5a in rat liver: direct and indirect actions on nonparenchymal and parenchymal cells
    • COI: 1:CAS:528:DC%2BD3MXisVyiurc%3D, PID: 11367531
    • Schieferdecker HL, Schlaf G, Jungermann K, Gotze O (2001) Functions of anaphylatoxin C5a in rat liver: direct and indirect actions on nonparenchymal and parenchymal cells. Int Immunopharmacol 1:469–481
    • (2001) Int Immunopharmacol , vol.1 , pp. 469-481
    • Schieferdecker, H.L.1    Schlaf, G.2    Jungermann, K.3    Gotze, O.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.