Iron Deficiency Anemia in Children

Indian Journal of Pediatrics

Volumn 82, Issue 6, 2015, Pages 558-564

  Subramaniam, Girish ^a,c   Girish, Meenakshi ^b  

^a Midas Heights   (India)

^b NKP SALVE INSTITUTE OF MEDICAL SCIENCES   (India)

^c Rahate Colony ^*  (India)

Author keywords

Clinical features; Iron deficiency; Management

Indexed keywords

IRON;

ANEMIA, IRON-DEFICIENCY; BETA-THALASSEMIA; BLOOD; DIFFERENTIAL DIAGNOSIS; EARLY INTERVENTION; HUMAN; INFANT; MEAN CORPUSCULAR VOLUME; METABOLISM; PRESCHOOL CHILD;

ANEMIA, IRON-DEFICIENCY; BETA-THALASSEMIA; CHILD, PRESCHOOL; DIAGNOSIS, DIFFERENTIAL; EARLY MEDICAL INTERVENTION; ERYTHROCYTE INDICES; HUMANS; INFANT; IRON;

EID: 84939953152     PISSN: 00195456     EISSN: 09737693     Source Type: Journal    
DOI: 10.1007/s12098-014-1643-9     Document Type: Review

References (28)

1. Brittenham GM. Disorders of iron metabolism: Iron deficiency and overload. In: Hoffman R, Benz Jr EJ, Shattil SJ, editors. Hematology Basic Principles and Practice. 4th ed. New York: Churchill Livingstone; 2005. p. 481.
2. Conrad ME, Umbreit JN. Iron absorption and transport-an update. Am J Hematol. 2000;64:287–98.
3. Kumar A, Rai AK, Basu S, Dash D, Singh JS. Cord blood and breast milk iron status in maternal anemia. Pediatrics. 2008;121:e673–7.
4. Calvo EB, Galindo AC, Aspres NB. Iron status in exclusively breast-fed infants. Pediatrics. 1992;90:375–9.
5. Ziegler EE, Fomon SJ, Nelson SE, Rebouche CJ, Edwards BB, Rogers RR, et al. Cow milk feeding in infancy: further observations on blood loss from the gastrointestinal tract. J Pediatr. 1990;116:11–8.
6. Sutcliffe TL, Khambalia A, Westergard S, Jacobson S, Peer M, Parkin PC. Iron depletion is associated with daytime bottle-feeding in the second and third years of life. Arch Pediatr Adolesc Med. 2006;160:1114–20.
7. Oski FA, Honig AS, Helu B, Howanitz P. Effect of iron therapy on behaviour performance in nonanemic, iron deficient infants. Pediatrics. 1983;71:877–80.
8. Akman M, Cebeci D, Okur V, Angin H, Abali O, Akman AC. The effects of iron deficiency on infant developmental test performance. Acta Pediatr. 2004;93:1391–6.
9. Thibault H, Galan P, Selz F, Preziosi P, Olivier C, Badoual J, et al. The immune response in iron-deficient young children: effect of iron supplementation on cell-mediated immunity. Eur J Pediatr. 1993;152:120–4.
10. Galan P, Thibault H, Preziosi P, Hercberg S. Interleukin 2 production in iron-deficient children. Biol Trace Elem Res. 1992;32:421–6.
11. Ekiz C, Agaoglu L, Karakas Z, Gurel N, Yalcin I. The effect of iron deficiency anemia on the function of the immune system. Hematol J. 2005;5:579–83.
12. Gera T, Sachdev HP. Effect of iron supplementation on incidence of infectious illness in children: systematic review. BMJ. 2002;325:1142.
13. Gwamaka M, Kurtis J, Sorensen B, Holte S, Morrison R, Mutabingwa TK, et al. Iron deficiency protects against severe plasmodium falciparum malaria and death in young children. Clin Infect Dis. 2012;54:1137–44.
14. Oppenheimer SJ, Gibson FD, Macfarlane SB, Moody JB, Harrison C, Spencer A, et al. Iron supplementation has been reported to increase the prevalence and effects of malaria: report on clinical studies in Papua New Guinea. Trans R Soc Trop Med Hyg. 1986;80:603–12.
15. Smith AW, Hendrickse RG, Harrison C, Hayes RJ, Greenwood BM. The effects on malaria of treatment of iron deficiency anemia with oral iron in Gambian children. Ann Trop Paediatr. 1989;9:17–23.
16. Ianotti LL, Tielsch JM, Black MM, Black RE. Iron supplementation in early childhood: health benefits and risks. Am J Clin Nutr. 2006;84:1261–76.
17. Mebrahtu T, Stolzfus RJ, Chwaya HM, Jape JK, Savioli L, Montresor A, et al. Low dose daily iron supplementation for 12 mo does not increase the prevalence of malarial infection or density of parasites in young Zanzibari children. J Nutr. 2004;134:3037–41.
18. Menendez C, Kahigwa E, Hirt R, Vounatsou P, Aponte JJ, Font F, et al. Randomised placebo controlled trial of iron supplementation and malaria chemoprophylaxis for prevention of severe anemia and malaria in Tanzanian infants. Lancet. 1997;350:844–50.
19. Brown WD, Dyment PG. Pagophagia and iron deficiency anemia in adolescent girls. Pediatrics. 1972;49:766–7.
20. Maguire JL, de Veber G, Parkin PC. Association between iron-deficiency anemia and stroke in young children. Pediatrics. 2007;120:1053–7.
21. Zehetner AA, Orr N, Buckmaster A, Williams K, Wheeler DM. Iron supplementation for breath-holding attacks in children. Cochrane Database Syst Rev. 2010. doi:10.1002/14651858.CD008132.pub2.
22. Schilling RF. Anemia of chronic disease: a misnomer. Ann Intern Med. 1991;115:572–3.
23. Suominen P, Motttonen T, Rajamaki A, Irjala K. Single values of serum transferring receptor and transferring receptor ferritin index can be used to detect true and functional iron deficiency in rheumatoid arthritis patients with anemia. Arthritis Rheum. 2000;43:1016–20.
24. American Academy of Pediatrics. Iron. In: Kleinman RE, Greer FR, editors. Pediatric nutrition. 7th ed. Elk Grove Village: American Academy of Pediatrics; 2011. p. 449.
25. Hallberg L, Brune M, Rossander L. Effect of ascorbic acid on iron absorption from different types of meals. Studies with ascorbic acid rich foods and synthetic ascorbic acid given in different amounts with different meals. Hum Nutr Appl Nutr. 1986;40:97.
26. Committee on Obstetric Practice, American College of Obstetricians and Gynecologists. Committee opinion No. 543: timing of umbilical cord clamping after birth. Obstet Gynecol. 2012;120:1522–6.
27. Adish AA, Esrey SA, Gyorkos TW, Jean-Baptiste J, Rojhani A. Effect of consumption of food cooked in iron pots on iron status and growth of young children: a randomised trial. Lancet. 1999;353:712–6.
28. Kotecha PV. Nutritional anemia in young children with focus on Asia and India. Indian J Community Med. 2011;36:8–16.