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Volumn 38, Issue 3, 2015, Pages 1221-1228

Platycodin D Attenuates Airway Inflammation in a Mouse Model of Allergic Asthma by Regulation NF-κB Pathway

Author keywords

asthma; NF B pathway; platycodin D

Indexed keywords

ANTIASTHMATIC AGENT; ANTIINFLAMMATORY AGENT; DEXAMETHASONE; I KAPPA B; I KAPPA B KINASE; INTERLEUKIN 13; INTERLEUKIN 4; INTERLEUKIN 5; NF-KAPPAB INHIBITOR ALPHA; OVALBUMIN; PLANT EXTRACT; PLATYCODIN D; RELA PROTEIN, MOUSE; SAPONIN; TRANSCRIPTION FACTOR RELA; TRITERPENE;

EID: 84939937880     PISSN: 03603997     EISSN: 15732576     Source Type: Journal    
DOI: 10.1007/s10753-014-0089-6     Document Type: Article
Times cited : (44)

References (21)
  • 3
    • 0036882155 scopus 로고    scopus 로고
    • TH2 cytokine expression in bronchoalveolar lavage fluid T lymphocytes and bronchial submucosa is a feature of asthma and eosinophilic bronchitis
    • COI: 1:CAS:528:DC%2BD3sXlvFensA%3D%3D, PID: 12464957
    • Brightling, C.E., F.A. Symon, S.S. Birring, et al. 2002. TH2 cytokine expression in bronchoalveolar lavage fluid T lymphocytes and bronchial submucosa is a feature of asthma and eosinophilic bronchitis. Journal of Allergy and Clinical Immunology 110: 899–905.
    • (2002) Journal of Allergy and Clinical Immunology , vol.110 , pp. 899-905
    • Brightling, C.E.1    Symon, F.A.2    Birring, S.S.3
  • 4
    • 0026610142 scopus 로고
    • Predominant TH2-like bronchoalveolar T-lymphocyte population in atopic asthma
    • COI: 1:STN:280:DyaK387gtVWnsQ%3D%3D, PID: 1530827
    • Robinson, D.S., Q. Hamid, S. Ying, et al. 1992. Predominant TH2-like bronchoalveolar T-lymphocyte population in atopic asthma. New England Journal of Medicine 326: 298–304.
    • (1992) New England Journal of Medicine , vol.326 , pp. 298-304
    • Robinson, D.S.1    Hamid, Q.2    Ying, S.3
  • 5
    • 0037393323 scopus 로고    scopus 로고
    • IL-13 receptors and signaling pathways: an evolving web
    • COI: 1:CAS:528:DC%2BD3sXjs1equ78%3D, PID: 12704343
    • Hershey, G.K. 2003. IL-13 receptors and signaling pathways: an evolving web. Journal of Allergy and Clinical Immunology 111: 677–690.
    • (2003) Journal of Allergy and Clinical Immunology , vol.111 , pp. 677-690
    • Hershey, G.K.1
  • 6
    • 84865134805 scopus 로고    scopus 로고
    • Short-term roxithromycin treatment attenuates airway inflammation via MAPK/NF-kappaB activation in a mouse model of allergic asthma
    • COI: 1:CAS:528:DC%2BC38XosFSltb4%3D, PID: 22481373, 7. L.-K
    • Ci, X., X. Chu, X. Xu, H. Li, and X. Deng. 2012. Short-term roxithromycin treatment attenuates airway inflammation via MAPK/NF-kappaB activation in a mouse model of allergic asthma. Inflammation Research 61: 749–58. 7. L.-K.
    • (2012) Inflammation Research , vol.61 , pp. 749-758
    • Ci, X.1    Chu, X.2    Xu, X.3    Li, H.4    Deng, X.5
  • 7
    • 0033735626 scopus 로고    scopus 로고
    • Platycodi radix affects lipid metabolism in mice with high fat diet-induced obesity
    • COI: 1:CAS:528:DC%2BD3cXnvVOlt7s%3D, PID: 11053518
    • Han, B., J. Xu, and Y. Kimura. 2000. Platycodi radix affects lipid metabolism in mice with high fat diet-induced obesity. Journal of Nutrition 130(11): 2760–2764.
    • (2000) Journal of Nutrition , vol.130 , Issue.11 , pp. 2760-2764
    • Han, B.1    Xu, J.2    Kimura, Y.3
  • 8
    • 0036322011 scopus 로고    scopus 로고
    • Saponins from Platycodi radix ameliorate high fat diet-induced obesity in mice
    • COI: 1:CAS:528:DC%2BD38XmtF2qtr0%3D, PID: 12163669
    • Han, L.-K., Y.-N. Zheng, B.-J. Xu, H. Okuda, and Y. Kimura. 2002. Saponins from Platycodi radix ameliorate high fat diet-induced obesity in mice. Journal of Nutrition 132(8): 2241–2245.
    • (2002) Journal of Nutrition , vol.132 , Issue.8 , pp. 2241-2245
    • Han, L.-K.1    Zheng, Y.-N.2    Xu, B.-J.3    Okuda, H.4    Kimura, Y.5
  • 9
    • 0034743436 scopus 로고    scopus 로고
    • Inhibition of prostaglandin E2 production by platycodin D isolated from the root of Platycodon grandiflorum
    • COI: 1:CAS:528:DC%2BD3MXltVWhs7k%3D, PID: 11458457
    • Kim, Y.P., E.B. Lee, and S.Y. Kim. 2001. Inhibition of prostaglandin E2 production by platycodin D isolated from the root of Platycodon grandiflorum. Planta Medica 67(4): 362–364.
    • (2001) Planta Medica , vol.67 , Issue.4 , pp. 362-364
    • Kim, Y.P.1    Lee, E.B.2    Kim, S.Y.3
  • 10
    • 43049141875 scopus 로고    scopus 로고
    • Platycodin D induces mitotic arrest in vitro, leading to endoreduplication, inhibition of proliferation and apoptosis in leukemia cells
    • COI: 1:CAS:528:DC%2BD1cXht1eku73K
    • Kim, M.-O., D.-O. Moon, H.C. Yung, J.-D. Lee, D.K. Nam, and G.-Y. Kim. 2008. Platycodin D induces mitotic arrest in vitro, leading to endoreduplication, inhibition of proliferation and apoptosis in leukemia cells. International Journal of Cancer 122(12): 2674–2681.
    • (2008) International Journal of Cancer , vol.122 , Issue.12 , pp. 2674-2681
    • Kim, M.-O.1    Moon, D.-O.2    Yung, H.C.3    Lee, J.-D.4    Nam, D.K.5    Kim, G.-Y.6
  • 11
    • 0036748248 scopus 로고    scopus 로고
    • Antinociceptive mechanisms of platycodin D administered intracerebroventricularly in the mouse
    • COI: 1:CAS:528:DC%2BD38XotVGnsrY%3D, PID: 12357389
    • Choi, S.-S., E.-J. Han, T.-H. Lee, et al. 2002. Antinociceptive mechanisms of platycodin D administered intracerebroventricularly in the mouse. Planta Medica 68(9): 794–798.
    • (2002) Planta Medica , vol.68 , Issue.9 , pp. 794-798
    • Choi, S.-S.1    Han, E.-J.2    Lee, T.-H.3
  • 12
    • 58249097459 scopus 로고    scopus 로고
    • Platycodin D is a potent adjuvant of specific cellular and humoral immune responses against recombinant hepatitis B antigen
    • COI: 1:CAS:528:DC%2BD1MXmvVOgsw%3D%3D, PID: 19041358
    • Xie, Y., H.-X. Sun, and D. Li. 2009. Platycodin D is a potent adjuvant of specific cellular and humoral immune responses against recombinant hepatitis B antigen. Vaccine 27(5): 757–764.
    • (2009) Vaccine , vol.27 , Issue.5 , pp. 757-764
    • Xie, Y.1    Sun, H.-X.2    Li, D.3
  • 13
    • 33646080805 scopus 로고    scopus 로고
    • Suppressive effect of verproside isolated from Pseudolysimachion longifolium on airway inflammation in a mouse model of allergic asthma
    • COI: 1:CAS:528:DC%2BD28XjvV2qtLs%3D, PID: 16644484
    • Oh, S.R., M.Y. Lee, K. Ahn, B.Y. Park, O.K. Kwon, H. Joung, J. Lee, D.Y. Kim, S. Lee, J.H. Kim, and H.K. Lee. 2006. Suppressive effect of verproside isolated from Pseudolysimachion longifolium on airway inflammation in a mouse model of allergic asthma. International Immunopharmacology 6: 978–86.
    • (2006) International Immunopharmacology , vol.6 , pp. 978-986
    • Oh, S.R.1    Lee, M.Y.2    Ahn, K.3    Park, B.Y.4    Kwon, O.K.5    Joung, H.6    Lee, J.7    Kim, D.Y.8    Lee, S.9    Kim, J.H.10    Lee, H.K.11
  • 15
    • 2442712697 scopus 로고    scopus 로고
    • Anti inflammatory effects of mitogen-activated protein kinase inhibitor U0126 in an asthma mouse model
    • COI: 1:CAS:528:DC%2BD2cXktFSkuro%3D, PID: 15153527
    • Duan, W., J.H. Chan, C.H. Wong, B.P. Leung, and W.S. Wong. 2004. Anti inflammatory effects of mitogen-activated protein kinase inhibitor U0126 in an asthma mouse model. The Journal of Immunology 172: 7053–7059.
    • (2004) The Journal of Immunology , vol.172 , pp. 7053-7059
    • Duan, W.1    Chan, J.H.2    Wong, C.H.3    Leung, B.P.4    Wong, W.S.5
  • 16
    • 33747756534 scopus 로고    scopus 로고
    • Asthma: defining of the persistent adult phenotypes
    • COI: 1:CAS:528:DC%2BD28XoslOjt7g%3D, PID: 16935691
    • Wenzel, S.E. 2006. Asthma: defining of the persistent adult phenotypes. Lancet 368: 804–13.
    • (2006) Lancet , vol.368 , pp. 804-813
    • Wenzel, S.E.1
  • 17
    • 0033053536 scopus 로고    scopus 로고
    • Regulation and modulation of eosinophil effector functions
    • COI: 1:CAS:528:DyaK1MXitFGmsbk%3D, PID: 10195355
    • Elsner, J., and A. Kapp. 1999. Regulation and modulation of eosinophil effector functions. Allergy 54: 15–22.
    • (1999) Allergy , vol.54 , pp. 15-22
    • Elsner, J.1    Kapp, A.2
  • 18
    • 0036290661 scopus 로고    scopus 로고
    • Nuclear factor (NF)-kappa B blockade attenuates but does not abrogate LPS-mediated interleukin (IL)-1 beta biosynthesis in alveolar epithelial cells
    • COI: 1:CAS:528:DC%2BD38XksVGitb4%3D, PID: 12054592
    • Haddad, J.J. 2002. Nuclear factor (NF)-kappa B blockade attenuates but does not abrogate LPS-mediated interleukin (IL)-1 beta biosynthesis in alveolar epithelial cells. Biochemical and Biophysical Research Communications 293: 252–257.
    • (2002) Biochemical and Biophysical Research Communications , vol.293 , pp. 252-257
    • Haddad, J.J.1
  • 19
    • 0036838764 scopus 로고    scopus 로고
    • Respiratory syncytial virus-induced activation of nuclear factor-kappaB in the lung involves alveolar macrophages and toll-like receptor 4-dependent pathways
    • COI: 1:CAS:528:DC%2BD38XovFKjtrg%3D, PID: 12402188
    • Haeberle, H.A., R. Takizawa, A. Casola, A.R. Brasier, H.J. Dieterich, N. Van Rooijen, et al. 2002. Respiratory syncytial virus-induced activation of nuclear factor-kappaB in the lung involves alveolar macrophages and toll-like receptor 4-dependent pathways. Journal of Infectious Diseases 186: 1199–1206.
    • (2002) Journal of Infectious Diseases , vol.186 , pp. 1199-1206
    • Haeberle, H.A.1    Takizawa, R.2    Casola, A.3    Brasier, A.R.4    Dieterich, H.J.5    Van Rooijen, N.6
  • 20
    • 0036102865 scopus 로고    scopus 로고
    • Rapid activation of nuclear factor-kappaB in airway epithelium in a murine model of allergic airway inflammation
    • COI: 1:CAS:528:DC%2BD38XjsFGjtrs%3D, PID: 11943717
    • Poynter, M.E., C.G. Irvin, and Y.M. Janssen-Heininger. 2002. Rapid activation of nuclear factor-kappaB in airway epithelium in a murine model of allergic airway inflammation. American Journal of Pathology 160: 1325–1334.
    • (2002) American Journal of Pathology , vol.160 , pp. 1325-1334
    • Poynter, M.E.1    Irvin, C.G.2    Janssen-Heininger, Y.M.3
  • 21
    • 0032476742 scopus 로고    scopus 로고
    • Essential role of nuclear factor kappaB in the induction of eosinophilia in allergic airway inflammation
    • COI: 1:CAS:528:DyaK1cXntFOmt7w%3D, PID: 9802985
    • Yang, L., L. Cohn, D.H. Zhang, R. Homer, A. Ray, and P. Ray. 1998. Essential role of nuclear factor kappaB in the induction of eosinophilia in allergic airway inflammation. Journal of Experimental Medicine 188: 1739–1750.
    • (1998) Journal of Experimental Medicine , vol.188 , pp. 1739-1750
    • Yang, L.1    Cohn, L.2    Zhang, D.H.3    Homer, R.4    Ray, A.5    Ray, P.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.