Detecting COPD exacerbations early using daily telemonitoring of symptoms and k-means clustering: a pilot study

Medical and Biological Engineering and Computing

Volumn 53, Issue 5, 2015, Pages 441-451

  Sanchez Morillo, Daniel ^a   Fernandez Granero, Miguel Angel ^a   Jiménez, Antonio León ^b  

^a UNIVERSITY OF CÁDIZ   (Spain)

^b HOSPITAL UNIVERSITARIO PUERTA DEL MAR   (Spain)

Author keywords

COPD; Early detection; Exacerbation; Questionnaire; Symptoms; Telehealth

Indexed keywords

MEDICAL COMPUTING; PATTERN RECOGNITION; SURVEYS;

COPD; EXACERBATION; QUESTIONNAIRE; SYMPTOMS; TELEHEALTH;

CLUSTERING ALGORITHMS;

AGED; ALGORITHM; CLUSTER ANALYSIS; FEMALE; HUMAN; MALE; MIDDLE AGED; PATHOPHYSIOLOGY; PILOT STUDY; PROCEDURES; PULMONARY DISEASE, CHRONIC OBSTRUCTIVE; SIGNAL PROCESSING; TELEMEDICINE; TELEMETRY; VERY ELDERLY;

AGED; AGED, 80 AND OVER; ALGORITHMS; CLUSTER ANALYSIS; FEMALE; HUMANS; MALE; MIDDLE AGED; PILOT PROJECTS; PULMONARY DISEASE, CHRONIC OBSTRUCTIVE; SIGNAL PROCESSING, COMPUTER-ASSISTED; TELEMEDICINE; TELEMETRY;

EID: 84939936252     PISSN: 01400118     EISSN: 17410444     Source Type: Journal    
DOI: 10.1007/s11517-015-1252-4     Document Type: Article

References (52)

1. Aaron SD, Donaldson GC, Whitmore GA, Hurst JR, Ramsay T, Wedzicha JA (2012) Time course and pattern of COPD exacerbation onset. Thorax 67:238–243
2. Almagro P, Barreiro B, Ochoa de Echaguen A, Quintana S, Rodríguez Carballeira M, Heredia JL, Garau J (2006) Risk factors for hospital readmission in patients with chronic obstructive pulmonary disease. Respiration 73:311–317
3. Anthonisen NR, Manfreda J, Warren CP, Hershfield ES, Harding GK, Nelson NA (1987) Antibiotic therapy in exacerbations of chronic obstructive pulmonary disease. Ann Intern Med 106:196–204
4. Antoniades NC, Rochford PD, Pretto JJ et al (2012) Pilot study of remote telemonitoring in COPD. Telemed J E Health 18:634–640
5. Bennett AV, Amtmann D, Diehr P, Patrick DL (2012) Comparison of 7-day recall and daily diary reports of COPD symptoms and impacts. Value Health 15:466–474
6. Bolton CE, Waters CS, Peirce S, Elwyn G, EPSRC and MRC Grand Challenge Team (2011) Insufficient evidence of benefit: a systematic review of home telemonitoring for COPD. J Eval Clin Pract 17:1216–1222
7. Chang C, Guo Z, Shen N, He B, Yao W, Zhu H, Zhao J (2014) Dynamics of inflammation resolution and symptom recovery during AECOPD treatment. Sci Rep 4:5516
8. Chau JP-C, Lee DT-F, Yu DS-F et al (2012) A feasibility study to investigate the acceptability and potential effectiveness of a telecare service for older people with chronic obstructive pulmonary disease. Int J Med Inform 81:674–682
9. De San Miguel K, Smith J, Lewin G (2013) Telehealth remote monitoring for community-dwelling older adults with chronic obstructive pulmonary disease. Telemed J E Health 19:652–657
10. Divo M, Cote C, de Torres JP, Casanova C, Marin JM et al (2012) Comorbidities and risk of mortality in patients with chronic obstructive pulmonary disease. Am J Respir Crit Care Med 186:155–161
11. Effing TW, Kerstjens HA, Monninkhof EM, van der Valk PD, Wouters EF et al (2009) Definitions of exacerbations: does it really matter in clinical trials on COPD? Chest 136:918–923
12. Engels JM, Diehr P (2003) Imputation of missing longitudinal data: a comparison of methods. J Clin Epidemiol 56:968–976
13. Espinosa de los Monteros MJ, Peña C, Soto Hurtado EJ, Jareño J, Miravitlles M (2012) Variability of respiratory symptoms in severe COPD. Arch Bronconeumol (English Edition) 48(1):3–7
14. Foix LC, Morillo DS, Crespo M, Gross N, Kunze C, Giokas K, Jimenez JA (2009) AMICA telemedicine platform: a design for management of elderly people with COPD. Proceedings of the 9th International Conference of the IEEE Information Technology and Applications in Biomedicine, Larnaca, Cyprus, IEEE Conference Publications, pp 1–4
15. Global Strategy for the Diagnosis, Management and Prevention of COP (2014) Global initiative for chronic obstructive lung disease (GOLD). http://www.goldcopd.org/. Accessed 24 Nov 2014
16. Goldstein RS, O’Hoski S (2014) Telemedicine in COPD: time to pause. Chest 145(5):945–949
17. Hartigan JA, Wong MA (1979) A k-means clustering algorithm. Appl Stat 28:100–108
18. Henderson C, Knapp M, Fernández J-L, Beecham J, Hirani SP, Cartwright M et al (2013) Cost effectiveness of telehealth for patients with long term conditions (Whole Systems Demonstrator telehealth questionnaire study): nested economic evaluation in a pragmatic, cluster randomised controlled trial. BMJ 346:f1035
19. Hurst JR, Donaldson G, Quint JK, Goldring JJP, Patel ARC, Wedzicha JA et al (2010) Domiciliary pulse-oximetry at exacerbation of chronic obstructive pulmonary disease: prospective pilot study. BMC Pulm Med 10:52–58
20. Jadwiga WA, Donaldson GC (2003) Exacerbations of chronic obstructive pulmonary disease. Respir Care 48:1204–1215
21. Jenkins CR, Celli B, Anderson JA, Ferguson GT, Jones PW, Vestbo J, Yates JC, Calverley PM (2012) Seasonality and determinants of moderate and severe COPD exacerbations in the TORCH study. Eur Respir J 39:38–45
22. Jensen MH, Cichosz SL, Dinesen B, Hejlesen OK (2012) Moving prediction of exacerbation in chronic obstructive pulmonary disease for patients in telecare. J Telemed Telecare 18:99–103
23. Jodar-Sanchez F, Ortega F, Calderon CP et al (2013) Implementation of a telehealth programme for patients with severe chronic obstructive pulmonary disease treated with long-term oxygen therapy. J Telemed Telecare 19:11–17
24. Jones PW, Harding G, Berry P, Wiklund I, Chen WH, Kline Leidy N (2009) Development and first validation of the COPD assessment test. Eur Respir J 34:648–654
25. Koff PB, Jones RH, Cashman JM, Voelkel NF, Vandivier RW (2009) Proactive integrated care improves quality of life in patients with COPD. Eur Respir J 33:1031–1038
26. Langsetmo L, Platt RW, Ernst P, Bourbeau J (2008) Underreporting exacerbation of chronic obstructive pulmonary disease in a longitudinal cohort. Am J Respir Crit Care Med 177:396–401
27. Leidy NK, Wilcox TK, Jones PW, Murray L, Winnette R, Howard K, Petrillo J, Powers J, Sethi S (2010) Development of the EXAcerbations of chronic obstructive pulmonary disease tool (EXACT): a patient-reported outcome (PRO) measure. Value Health 13:965–975
28. Lewis KE, Annandale JA, Warm DL et al (2010) Does home telemonitoring after pulmonary rehabilitation reduce healthcare use in optimized COPD? A pilot randomized trial. COPD 7:44–50
29. Mackay AJ, Donaldson GC, Patel AR et al (2014) Detection and severity grading of COPD exacerbations using the exacerbations of chronic obstructive pulmonary disease tool (EXACT). Eur Respir J 43(3):735–744
30. McKinstry B (2013) The use of remote monitoring technologies in managing chronic obstructive pulmonary disease. QJM 106:883–885
31. Metz CE (1978) Basic principles of ROC analysis. Semin Nucl Med 8:283–298
32. Ong KC, Earnest A, Lu SJ (2005) A multidimensional grading system (BODE index) as predictor of hospitalization for COPD. Chest 128:3810–3816
33. Pare G, Sicotte C, St.-Jules D, Gauthier R (2006) Cost minimization analysis of a tele home care program for patients with chronic obstructive pulmonary disease. Telemed J E Health 12:114–121
34. Pedone C, Chiurco D, Scarlata S, Antonelli Incalzi R (2013) Efficacy of multiparametric telemonitoring on respiratory outcomes in elderly people with COPD: a randomized controlled trial. BMC Health Serv Res 13:82
35. Pinnock H, Hanley J, McCloughan L, Todd A, Krishan A et al (2013) Effectiveness of telemonitoring integrated into existing clinical services on hospital admission for exacerbation of chronic obstructive pulmonary disease: researcher blind, multicentre, randomised controlled trial. BMJ Br Med J 347:f6070
36. Sánchez-Morillo D, Crespo M, León A, Crespo Foix LF (2015) A novel multimodal tool for telemonitoring patients with COPD. Inform Health Soc Care 40(1):1–22
37. Sanders C, Rogers A, Bowen R, Bower P, Hirani S et al (2012) Exploring barriers to participation and adoption of telehealth and telecare within the whole system demonstrator trial: a qualitative study. BMC Health Serv Res 12:220
38. Seemungal TA, Donaldson GC, Bhowmik A, Jeffries DJ, Wedzicha JA (2000) Time course and recovery of exacerbations in patients with chronic obstructive pulmonary disease. Am J Respir Crit Care Med 161:1608–1613
39. Seemungal TA, Hurst JR, Wedzicha JA (2009) Exacerbation rate, health status and mortality in COPD—a review of potential interventions. Int J Chron Obstruct Pulmon Dis 4:203–223
40. Sund ZM, Powell T, Greenwood R, Jarad NA (2009) Remote daily real-time monitoring in patients with COPD—a feasibility study using a novel device. Resp Med 103:1320–1328
41. Toy EL, Gallagher KF, Stanley EL, Swensen AR, Duh MS (2010) The economic impact of exacerbations of chronic obstructive pulmonary disease and exacerbation definition: a review. COPD 7:214–228
42. Trappenburg JCA, Niesink A, de Weert-van Oene GH et al (2008) Effects of telemonitoring in patients with chronic obstructive pulmonary disease. Telemed J E Health 14:138–146
43. Trappenburg J, Touwen I, Oene G, Bourbeau J, Monninkhof E et al (2010) Detecting exacerbations using the clinical COPD questionnaire. Health Qual Life Outcomes 8:102
44. Ure J, Pinnock H, Hanley J, Kidd G, McCall Smith E et al (2012) Piloting tele-monitoring in COPD: a mixed methods exploration of issues in design and implementation. Prim Care Resp J 21:57–64
45. van der Heijden M, Lucas PJ, Lijnse B, Heijdra YF, Schermer TR (2013) An autonomous mobile system for the management of COPD. J Biomed Inform 46:458–469
46. van der Molen T, Willemse BW, Schokker S, ten Hacken NH, Postma DS, Juniper EF (2003) Development, validity and responsiveness of the clinical COPD questionnaire. Health Qual Life Outcomes 1:13
47. Venter A, Burns R, Hefford M, Ehrenberg N (2012) Results of a telehealth-enabled chronic care management service to support people with long-term conditions at home. J Telemed Telecare 18:172–175
48. Walters E, Walters J, Wills K, Robinson A, Wood-Baker R (2012) Clinical diaries in COPD: compliance and utility in predicting acute exacerbations. Int J Chron Obstruct Pulmon Dis 7:427–435
49. Wilkinson T, Wedzicha JA (2006) Strategies for improving outcomes of COPD exacerbations. Int J Chron Obstruct Pulmon Dis 1:335–342
50. Wilkinson TM, Donaldson GC, Hurst JR, Seemungal TA, Wedzicha JA (2004) Early therapy improves outcomes of exacerbations of chronic obstructive pulmonary disease. Am J Respir Crit Care Med 169:1298–1303
51. Wu S, Falk TH, Chan WY (2011) Automatic speech emotion recognition using modulation spectral features. Speech Commun 53(5):768–785
52. Zhao W, Adolph AL, Puyau MR, Vohra FA, Butte NF, Zakeri IF (2013) Support vector machines classifiers of physical activities in preschoolers. Physiol Rep 1(1):e00006