Tonic inhibition of accumbal spiny neurons by extrasynaptic α4βδ GABAA receptors modulates the actions of psychostimulants

Journal of Neuroscience

Volumn 34, Issue 3, 2014, Pages 823-838

  Maguire, Edward P ^a   Macpherson, Tom ^b   Swinny, Jerome D ^c   Dixon, Claire I ^b   Herd, Murray B ^a   Belelli, Delia ^a   Stephens, David N ^b   King, Sarah L ^b   Lambert, Jeremy J ^b  

^a UNIVERSITY OF DUNDEE   (United Kingdom)

^b UNIVERSITY OF SUSSEX   (United Kingdom)

^c UNIVERSITY OF PORTSMOUTH   (United Kingdom)

Author keywords

Addiction; GABAA receptors; Gaboxadol; Nucleus accumbens; THIP

Indexed keywords

4 AMINOBUTYRIC ACID A RECEPTOR; 4 AMINOBUTYRIC ACID A RECEPTOR ALPHA4; 6 CHLORO 2,3,4,5 TETRAHYDRO 7,8 DIHYDROXY 1 PHENYL 1H 3 BENZAZEPINE; AMPHETAMINE; BICUCULLINE; CALRETININ; CHOLINE ACETYLTRANSFERASE; COCAINE; DOPAMINE 1 RECEPTOR; DOPAMINE 2 RECEPTOR; GABOXADOL; GRAMICIDIN; NEUROPEPTIDE Y; PARVALBUMIN; PHOSPHOPROTEIN DARPP 32; PSYCHOSTIMULANT AGENT; SOMATOSTATIN; TRITON X 100;

ADDICTION; ADULT; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BEHAVIOR; BRAIN ELECTROPHYSIOLOGY; CONDITIONED PLACE PREFERENCE TEST; CONFOCAL LASER SCANNING MICROSCOPE; CONTROLLED STUDY; CORPUS STRIATUM; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; LOCOMOTION; MALE; MEMBRANE STEADY POTENTIAL; MOUSE; NERVE EXCITABILITY; NONHUMAN; NUCLEUS ACCUMBENS; PRIORITY JOURNAL; SPINAL CORD NERVE CELL; STEREOTAXIC SURGERY; VOLTAGE CLAMP TECHNIQUE; WHOLE CELL PATCH CLAMP;

ADDICTION; GABAA RECEPTORS; GABOXADOL; NUCLEUS ACCUMBENS; THIP;

ANIMALS; CENTRAL NERVOUS SYSTEM STIMULANTS; CONDITIONING (PSYCHOLOGY); MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MICE, TRANSGENIC; NEURAL INHIBITION; NUCLEUS ACCUMBENS; RECEPTORS, GABA-A; SYNAPSES;

EID: 84892414921     PISSN: 02706474     EISSN: 15292401     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.3232-13.2014     Document Type: Article

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