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Volumn 10, Issue 1, 2015, Pages 99-109

A mutant BRAF V600E-specific immunohistochemical assay: correlation with molecular mutation status and clinical outcome in colorectal cancer

Author keywords

BRAF V600E; Colorectal cancer; Immunohistochemistry; VE1

Indexed keywords

B RAF KINASE; BRAF PROTEIN, HUMAN; TUMOR MARKER;

EID: 84939893109     PISSN: 17762596     EISSN: 1776260X     Source Type: Journal    
DOI: 10.1007/s11523-014-0319-8     Document Type: Article
Times cited : (49)

References (54)
  • 1
    • 0029944442 scopus 로고    scopus 로고
    • Ras effectors
    • COI: 1:CAS:528:DyaK28XitVWktbg%3D, PID: 8791426
    • Marshall CJ (1996) Ras effectors. Curr Opin Cell Biol 8:197–204
    • (1996) Curr Opin Cell Biol , vol.8 , pp. 197-204
    • Marshall, C.J.1
  • 4
    • 77950561234 scopus 로고    scopus 로고
    • A rapid, sensitive, reproducible and cost-effective method for mutation profiling of colon cancer and metastatic lymph nodes
    • PID: 20233444
    • Fumagalli D, Gavin PG, Taniyama Y, Kim SI, Choi HJ, Paik S, Pogue-Geile KL (2010) A rapid, sensitive, reproducible and cost-effective method for mutation profiling of colon cancer and metastatic lymph nodes. BMC Cancer 10:101
    • (2010) BMC Cancer , vol.10 , pp. 101
    • Fumagalli, D.1    Gavin, P.G.2    Taniyama, Y.3    Kim, S.I.4    Choi, H.J.5    Paik, S.6    Pogue-Geile, K.L.7
  • 5
    • 58249089525 scopus 로고    scopus 로고
    • CpG island methylator phenotype, microsatellite instability, BRAF mutation and clinical outcome in colon cancer
    • PID: 18832519
    • Ogino S, Nosho K, Kirkner GJ, Kawasaki T, Meyerhardt JA, Loda M, Giovannucci EL, Fuchs CS (2009) CpG island methylator phenotype, microsatellite instability, BRAF mutation and clinical outcome in colon cancer. Gut 58:90–96
    • (2009) Gut , vol.58 , pp. 90-96
    • Ogino, S.1    Nosho, K.2    Kirkner, G.J.3    Kawasaki, T.4    Meyerhardt, J.A.5    Loda, M.6    Giovannucci, E.L.7    Fuchs, C.S.8
  • 7
    • 79958817037 scopus 로고    scopus 로고
    • Impact of BRAF mutation and microsatellite instability on the pattern of metastatic spread and prognosis in metastatic colorectal cancer
    • COI: 1:CAS:528:DC%2BC3MXht1Kkur7M, PID: 21456008
    • Tran B, Kopetz S, Tie J, Gibbs P, Jiang ZQ, Lieu CH, Agarwal A, Maru DM, Sieber O, Desai J (2011) Impact of BRAF mutation and microsatellite instability on the pattern of metastatic spread and prognosis in metastatic colorectal cancer. Cancer 117:4623–4632
    • (2011) Cancer , vol.117 , pp. 4623-4632
    • Tran, B.1    Kopetz, S.2    Tie, J.3    Gibbs, P.4    Jiang, Z.Q.5    Lieu, C.H.6    Agarwal, A.7    Maru, D.M.8    Sieber, O.9    Desai, J.10
  • 10
    • 84862026304 scopus 로고    scopus 로고
    • Addition of cetuximab to chemotherapy as first-line treatment for KRAS wild-type metastatic colorectal cancer: pooled analysis of the CRYSTAL and OPUS randomised clinical trials
    • COI: 1:CAS:528:DC%2BC38XkvFSlsro%3D, PID: 22446022
    • Bokemeyer C, Van Cutsem E, Rougier P, Ciardiello F, Heeger S, Schlichting M, Celik I, Köhne CH (2012) Addition of cetuximab to chemotherapy as first-line treatment for KRAS wild-type metastatic colorectal cancer: pooled analysis of the CRYSTAL and OPUS randomised clinical trials. Eur J Cancer 48:1466–1475
    • (2012) Eur J Cancer , vol.48 , pp. 1466-1475
    • Bokemeyer, C.1    Van Cutsem, E.2    Rougier, P.3    Ciardiello, F.4    Heeger, S.5    Schlichting, M.6    Celik, I.7    Köhne, C.H.8
  • 11
    • 1642535480 scopus 로고    scopus 로고
    • BRAF mutation is frequently present in sporadic colorectal cancer with methylated hMLH1, but not in hereditary nonpolyposis colorectal cancer
    • COI: 1:CAS:528:DC%2BD2cXkvF2msA%3D%3D, PID: 14734469
    • Deng G, Bell I, Crawley S, Gum J, Terdiman JP, Allen BA, Truta B, Sleisenger MH, Kim YS (2004) BRAF mutation is frequently present in sporadic colorectal cancer with methylated hMLH1, but not in hereditary nonpolyposis colorectal cancer. Clin Cancer Res 10:191–195
    • (2004) Clin Cancer Res , vol.10 , pp. 191-195
    • Deng, G.1    Bell, I.2    Crawley, S.3    Gum, J.4    Terdiman, J.P.5    Allen, B.A.6    Truta, B.7    Sleisenger, M.H.8    Kim, Y.S.9
  • 14
    • 0017681196 scopus 로고
    • DNA sequencing with chain-terminating inhibitors
    • Sanger F, Nicklen S, Coulson AR (1977) DNA sequencing with chain-terminating inhibitors. Proc Natl Acad Sci 47:5463–5467
    • (1977) Proc Natl Acad Sci , vol.47 , pp. 5463-5467
    • Sanger, F.1    Nicklen, S.2    Coulson, A.R.3
  • 16
    • 84857232726 scopus 로고    scopus 로고
    • Analytical performance of a real-time PCR-based assay for V600 mutation in the BRAF gene, used as the companion diagnostic test for the novel BRAF inhibitor vemurafenib in metastatic melanoma
    • COI: 1:CAS:528:DC%2BC38XitFagtLg%3D, PID: 22306669
    • Halait H, Demartin K, Shah S, Soviero S, Langland R, Cheng S, Hillman G, Wu L, Lawrence HJ (2012) Analytical performance of a real-time PCR-based assay for V600 mutation in the BRAF gene, used as the companion diagnostic test for the novel BRAF inhibitor vemurafenib in metastatic melanoma. Diagn Mol Pathol 21:1–8
    • (2012) Diagn Mol Pathol , vol.21 , pp. 1-8
    • Halait, H.1    Demartin, K.2    Shah, S.3    Soviero, S.4    Langland, R.5    Cheng, S.6    Hillman, G.7    Wu, L.8    Lawrence, H.J.9
  • 24
    • 84873715417 scopus 로고    scopus 로고
    • Detection of the BRAF V600E mutation in serous ovarian tumours: a comparative analysis of immunohistochemistry with a mutation-specific monoclonal antibody and allele-specific PCR
    • PID: 23089489
    • Bösmüller H, Fischer A, Pham DL, Fehm T, Capper D, von Deimling A, Bonzheim I, Staebler A, Fend F (2013) Detection of the BRAF V600E mutation in serous ovarian tumours: a comparative analysis of immunohistochemistry with a mutation-specific monoclonal antibody and allele-specific PCR. Hum Pathol 44:329–335
    • (2013) Hum Pathol , vol.44 , pp. 329-335
    • Bösmüller, H.1    Fischer, A.2    Pham, D.L.3    Fehm, T.4    Capper, D.5    von Deimling, A.6    Bonzheim, I.7    Staebler, A.8    Fend, F.9
  • 26
    • 84865001178 scopus 로고    scopus 로고
    • Detection of BRAF V600E mutations in skin metastases of malignant melanoma by monoclonal antibody VE1
    • COI: 1:CAS:528:DC%2BC38XhtF2itLvO, PID: 22890732
    • Skorokhod A, Capper D, von Deimling A, Enk A, Helmbold P (2012) Detection of BRAF V600E mutations in skin metastases of malignant melanoma by monoclonal antibody VE1. J Am Acad Dermatol 67:488–491
    • (2012) J Am Acad Dermatol , vol.67 , pp. 488-491
    • Skorokhod, A.1    Capper, D.2    von Deimling, A.3    Enk, A.4    Helmbold, P.5
  • 30
    • 84870067191 scopus 로고    scopus 로고
    • Application of a BRAF V600E mutation-specific antibody for the diagnosis of hairy cell leukemia
    • PID: 22531170
    • Andrulis M, Penzel R, Weichert W, von Deimling A, Capper D (2012) Application of a BRAF V600E mutation-specific antibody for the diagnosis of hairy cell leukemia. Am J Surg Pathol 36:1796–1800
    • (2012) Am J Surg Pathol , vol.36 , pp. 1796-1800
    • Andrulis, M.1    Penzel, R.2    Weichert, W.3    von Deimling, A.4    Capper, D.5
  • 33
    • 27744600116 scopus 로고    scopus 로고
    • A simple and fast method for the simultaneous detection of nine fibroblast growth factor receptor 3 mutations in bladder cancer and voided urine
    • PID: 16278395
    • van Oers JMM, Lurkin I, van Exsel AJA, Nijsen Y, van Rhijn BWG, van der Aa MNM, Zwarthoff EC (2005) A simple and fast method for the simultaneous detection of nine fibroblast growth factor receptor 3 mutations in bladder cancer and voided urine. Clin Cancer Res 11:7743–7748
    • (2005) Clin Cancer Res , vol.11 , pp. 7743-7748
    • van Oers, J.M.M.1    Lurkin, I.2    van Exsel, A.J.A.3    Nijsen, Y.4    van Rhijn, B.W.G.5    van der Aa, M.N.M.6    Zwarthoff, E.C.7
  • 34
    • 77952536391 scopus 로고    scopus 로고
    • Two multiplex assays that simultaneously identify 22 possible mutation sites in the KRAS, BRAF, NRAS and PIK3CA genes
    • PID: 20098682
    • Lurkin I, Stoehr R, Hurst CD, van Tilborg AAG, Knowles MA, Hartmann A, Zwarthoff EC (2010) Two multiplex assays that simultaneously identify 22 possible mutation sites in the KRAS, BRAF, NRAS and PIK3CA genes. PLoS ONE 5:e8802
    • (2010) PLoS ONE , vol.5 , pp. 8802
    • Lurkin, I.1    Stoehr, R.2    Hurst, C.D.3    van Tilborg, A.A.G.4    Knowles, M.A.5    Hartmann, A.6    Zwarthoff, E.C.7
  • 36
    • 84970866422 scopus 로고
    • Diagnostic tests 1: sensitivity and specificity
    • COI: 1:STN:280:DyaK2c3ptVajug%3D%3D, PID: 8019315
    • Altman DG, Bland JM (1994) Diagnostic tests 1: sensitivity and specificity. BMJ 308:1552
    • (1994) BMJ , vol.308 , pp. 1552
    • Altman, D.G.1    Bland, J.M.2
  • 37
    • 84970846412 scopus 로고
    • Diagnostic tests 2: predictive values
    • COI: 1:STN:280:DyaK2czht12htQ%3D%3D, PID: 8038641
    • Altman DG, Bland JM (1994) Diagnostic tests 2: predictive values. BMJ 309:102
    • (1994) BMJ , vol.309 , pp. 102
    • Altman, D.G.1    Bland, J.M.2
  • 39
    • 32044455746 scopus 로고    scopus 로고
    • BRAF mutations are associated with distinctive clinical, pathological and molecular features of colorectal cancer independently of microsatellite instability status
    • PID: 16403224
    • Li WQ, Kawakami K, Ruszkiewicz A, Bennett G, Moore J, Iacopetta B (2006) BRAF mutations are associated with distinctive clinical, pathological and molecular features of colorectal cancer independently of microsatellite instability status. Mol Cancer 5:2
    • (2006) Mol Cancer , vol.5 , pp. 2
    • Li, W.Q.1    Kawakami, K.2    Ruszkiewicz, A.3    Bennett, G.4    Moore, J.5    Iacopetta, B.6
  • 47
    • 79961027120 scopus 로고    scopus 로고
    • Value and limitations of immunohistochemistry and gene sequencing for detection of the IDH1-R132H mutation in diffuse glioma biopsy specimens
    • COI: 1:CAS:528:DC%2BC3MXptVeqtrw%3D, PID: 21760534
    • Preusser M, Wöhrer A, Stary S, Höftberger R, Streubel B, Hainfellner JA (2011) Value and limitations of immunohistochemistry and gene sequencing for detection of the IDH1-R132H mutation in diffuse glioma biopsy specimens. J Neuropathol Exp Neurol 70:715–723
    • (2011) J Neuropathol Exp Neurol , vol.70 , pp. 715-723
    • Preusser, M.1    Wöhrer, A.2    Stary, S.3    Höftberger, R.4    Streubel, B.5    Hainfellner, J.A.6
  • 48
    • 33749067855 scopus 로고    scopus 로고
    • Recommendations for the care of individuals with an inherited predisposition to Lynch syndrome. A systematic review
    • COI: 1:CAS:528:DC%2BD28XhtVWmsrbL, PID: 17003399
    • Lindor NM, Petersen GM, Hadley DW, Kinney AY, Miesfeldt S, Lu KH, Lynch P, Burke W, Press N (2006) Recommendations for the care of individuals with an inherited predisposition to Lynch syndrome. A systematic review. JAMA 296:1507–1517
    • (2006) JAMA , vol.296 , pp. 1507-1517
    • Lindor, N.M.1    Petersen, G.M.2    Hadley, D.W.3    Kinney, A.Y.4    Miesfeldt, S.5    Lu, K.H.6    Lynch, P.7    Burke, W.8    Press, N.9
  • 49
    • 84880725363 scopus 로고    scopus 로고
    • Immunohistochemistry using the BRAF V600E mutation-specific monoclonal antibody VE1 is not a useful surrogate for genotyping in colorectal adenocarcinoma
    • PID: 23763264
    • Adackapara CA, Sholl LM, Barletta JA, Hornick JL (2013) Immunohistochemistry using the BRAF V600E mutation-specific monoclonal antibody VE1 is not a useful surrogate for genotyping in colorectal adenocarcinoma. Histopathology 63:187–193
    • (2013) Histopathology , vol.63 , pp. 187-193
    • Adackapara, C.A.1    Sholl, L.M.2    Barletta, J.A.3    Hornick, J.L.4
  • 50
    • 70350518191 scopus 로고    scopus 로고
    • Polyclonality of BRAF mutations in acquired melanocytic nevi
    • COI: 1:CAS:528:DC%2BD1MXhtlWksrrN, PID: 19752400
    • Lin J, Takata M, Goto Y, Kido K, Ferrone S, Saida T (2009) Polyclonality of BRAF mutations in acquired melanocytic nevi. J Natl Cancer Inst 101:1423–1427
    • (2009) J Natl Cancer Inst , vol.101 , pp. 1423-1427
    • Lin, J.1    Takata, M.2    Goto, Y.3    Kido, K.4    Ferrone, S.5    Saida, T.6
  • 51
    • 79551591312 scopus 로고    scopus 로고
    • Polyclonality of BRAF mutations in primary melanoma and the selection of mutant alleles during progression
    • COI: 1:CAS:528:DC%2BC3MXhsVOrs7c%3D, PID: 21224857
    • Lin J, Goto Y, Murata H, Sakaizawa K, Uchiyama A, Saida T, Takata M (2011) Polyclonality of BRAF mutations in primary melanoma and the selection of mutant alleles during progression. Br J Cancer 104:464–468
    • (2011) Br J Cancer , vol.104 , pp. 464-468
    • Lin, J.1    Goto, Y.2    Murata, H.3    Sakaizawa, K.4    Uchiyama, A.5    Saida, T.6    Takata, M.7
  • 53
    • 84872867965 scopus 로고    scopus 로고
    • Combined BRAFV600E-positive melanocytic lesions with large epithelioid cells lacking BAP1 expression and conventional nevomelanocytes
    • Busam KJ, Sung J, Wiesner T, von Deimling A, Jungbluth A (2012) Combined BRAFV600E-positive melanocytic lesions with large epithelioid cells lacking BAP1 expression and conventional nevomelanocytes. Am J Surg Pathol 37:193–199
    • (2012) Am J Surg Pathol , vol.37 , pp. 193-199
    • Busam, K.J.1    Sung, J.2    Wiesner, T.3    von Deimling, A.4    Jungbluth, A.5
  • 54
    • 84868626802 scopus 로고    scopus 로고
    • Mutation specific antibodies: tool or dinosaur?
    • von Deimling A, Sahm F, Capper D (2012) Mutation specific antibodies: tool or dinosaur? Oncotarget 3:907–908
    • (2012) Oncotarget , vol.3 , pp. 907-908
    • von Deimling, A.1    Sahm, F.2    Capper, D.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.