Internal threshold of toxicological concern values: enabling route-to-route extrapolation

Archives of Toxicology

Volumn 89, Issue 6, 2015, Pages 941-948

  Partosch, Falko ^a   Mielke, Hans ^b   Stahlmann, Ralf ^a   Kleuser, Burkhard ^c   Barlow, Susan ^d   Gundert Remy, Ursula ^a,b  

^a CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^b FEDERAL INSTITUTE FOR RISK ASSESSMENT   (Germany)

^c Abteilung Epidemiologie   (Germany)

^d VirologyConsult Ltd   (United Kingdom)

Author keywords

Animal free testing; Cosmetics; Internal TTC; TTC concept

Indexed keywords

XENOBIOTIC AGENT;

BIOAVAILABILITY; CLASSIFICATION; EUROPE; FACTUAL DATABASE; GOVERNMENT REGULATION; NO-OBSERVED-ADVERSE-EFFECT LEVEL; ORAL DRUG ADMINISTRATION; PROCEDURES; REFERENCE VALUE; RISK ASSESSMENT; STANDARDS; THRESHOLD LIMIT VALUE; TOXICITY TESTING;

ADMINISTRATION, ORAL; BIOLOGICAL AVAILABILITY; DATABASES, FACTUAL; EUROPE; GOVERNMENT REGULATION; NO-OBSERVED-ADVERSE-EFFECT LEVEL; REFERENCE VALUES; RISK ASSESSMENT; THRESHOLD LIMIT VALUES; TOXICITY TESTS; XENOBIOTICS;

EID: 84939890757     PISSN: 03405761     EISSN: 14320738     Source Type: Journal    
DOI: 10.1007/s00204-014-1287-6     Document Type: Article

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