Human adipose-Derived Mesenchymal Stem Cells Improve Motor Functions and are Neuroprotective in the 6-Hydroxydopamine-Rat Model for Parkinson’s Disease when Cultured in Monolayer Cultures but Suppress Hippocampal Neurogenesis and Hippocampal Memory Function when Cultured in Spheroids

Stem Cell Reviews and Reports

Volumn 11, Issue 1, 2015, Pages 133-149

  Berg, Jürgen ^a   Roch, Manfred ^a   Altschüler, Jennifer ^a   Winter, Christine ^b   Schwerk, Anne ^a   Kurtz, Andreas ^a   Steiner, Barbara ^a  

^a CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^b UNIVERSITY HOSPITAL CARL GUSTAV CARUS   (Germany)

Author keywords

Monolayer and sheproid cultured adipose derived stem cells; Parkinson s disease; Plasticity; Regeneration

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR; GLIAL FIBRILLARY ACIDIC PROTEIN; OXIDOPAMINE; TYROSINE 3 MONOOXYGENASE;

ADIPOSE TISSUE; ADULT; ANIMAL; CELL CULTURE; CELL DIFFERENTIATION; CHEMICALLY INDUCED; CONFOCAL MICROSCOPY; CULTURE TECHNIQUE; CYTOLOGY; DISEASE MODEL; FEMALE; GENETICS; HIPPOCAMPUS; HUMAN; MEMORY; MESENCHYMAL STEM CELL TRANSPLANTATION; MESENCHYMAL STROMA CELL; METABOLISM; MOTOR ACTIVITY; NERVOUS SYSTEM DEVELOPMENT; NEUROPROTECTION; PARKINSONIAN DISORDERS; PATHOPHYSIOLOGY; PHYSIOLOGY; PROCEDURES; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; WISTAR RAT; XENOGRAFT;

ADIPOSE TISSUE; ADULT; ANIMALS; BRAIN-DERIVED NEUROTROPHIC FACTOR; CELL CULTURE TECHNIQUES; CELL DIFFERENTIATION; CELLS, CULTURED; DISEASE MODELS, ANIMAL; FEMALE; GLIAL FIBRILLARY ACIDIC PROTEIN; HIPPOCAMPUS; HUMANS; MEMORY; MESENCHYMAL STEM CELL TRANSPLANTATION; MESENCHYMAL STROMAL CELLS; MICROSCOPY, CONFOCAL; MOTOR ACTIVITY; NEUROGENESIS; NEUROPROTECTION; OXIDOPAMINE; PARKINSONIAN DISORDERS; RATS, WISTAR; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; TRANSPLANTATION, HETEROLOGOUS; TYROSINE 3-MONOOXYGENASE;

EID: 84939889293     PISSN: 26293269     EISSN: 26293277     Source Type: Journal    
DOI: 10.1007/s12015-014-9551-y     Document Type: Article

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