Berberine diminishes side population and down-regulates stem cell-associated genes in the pancreatic cancer cell lines PANC-1 and MIA PaCa-2

Molecular and Cellular Biochemistry

Volumn 394, Issue 1-2, 2014, Pages 209-215

  Park, S H ^a   Sung, J H ^b   Chung, N ^a  

^a Korea University   (South Korea)

^b Seoul National University Hospital   (South Korea)

Author keywords

Berberine; Cancer stem cells; NANOG; Pancreatic cancer; POU5F1; Side population

Indexed keywords

ANTINEOPLASTIC AGENT; ANTINEOPLASTIC ANTIMETABOLITE; BERBERINE; DEOXYCYTIDINE; GEMCITABINE; HOMEODOMAIN PROTEIN; MESSENGER RNA; NANOG PROTEIN, HUMAN; NOTCH1 PROTEIN, HUMAN; NOTCH1 RECEPTOR; OCTAMER TRANSCRIPTION FACTOR 4; POU5F1 PROTEIN, HUMAN; SOX2 PROTEIN, HUMAN; TRANSCRIPTION FACTOR SOX; TUMOR MARKER;

ANALOGS AND DERIVATIVES; CANCER STEM CELL; CELL SURVIVAL; COMPARATIVE STUDY; DRUG EFFECTS; GENE EXPRESSION REGULATION; GENETICS; HUMAN; METABOLISM; PANCREAS TUMOR; PATHOLOGY; SIDE POPULATION CELL; SIGNAL TRANSDUCTION; TUMOR CELL LINE;

ANTIMETABOLITES, ANTINEOPLASTIC; ANTINEOPLASTIC AGENTS, PHYTOGENIC; BERBERINE; CELL LINE, TUMOR; CELL SURVIVAL; DEOXYCYTIDINE; GENE EXPRESSION REGULATION, NEOPLASTIC; HOMEODOMAIN PROTEINS; HUMANS; NEOPLASTIC STEM CELLS; OCTAMER TRANSCRIPTION FACTOR-3; PANCREATIC NEOPLASMS; RECEPTOR, NOTCH1; RNA, MESSENGER; SIDE-POPULATION CELLS; SIGNAL TRANSDUCTION; SOXB1 TRANSCRIPTION FACTORS; TUMOR MARKERS, BIOLOGICAL;

EID: 84939873677     PISSN: 03008177     EISSN: 15734919     Source Type: Journal    
DOI: 10.1007/s11010-014-2096-1     Document Type: Article

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