An alternative splicing event amplifies evolutionary differences between vertebrates

Science

Volumn 349, Issue 6250, 2015, Pages 868-873

  Gueroussov, Serge ^a   Gonatopoulos Pournatzis, Thomas ^a   Irimia, Manuel ^a,b   Raj, Bushra ^a   Lin, Zhen Yuan ^c   Gingras, Anne Claude ^a,c   Blencowe, Benjamin J ^a  

^a UNIVERSITY OF TORONTO   (Canada)

^b CENTRE FOR GENOMIC REGULATION CRG   (Spain)

^c MOUNT SINAI HOSPITAL   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

POLYPYRIMIDINE TRACT BINDING PROTEIN; POLYPYRIMIDINE TRACT BINDING PROTEIN 1; UNCLASSIFIED DRUG; HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN; PTBP1 PROTEIN, HUMAN; PTBP1 PROTEIN, MOUSE;

BRAIN; CELLS AND CELL COMPONENTS; ENZYME ACTIVITY; EVOLUTIONARY BIOLOGY; GENE EXPRESSION; GENETIC ENGINEERING; MAMMAL; PROTEIN; PROTEOMICS; VERTEBRATE;

ALTERNATIVE RNA SPLICING; ANIMAL CELL; ARTICLE; CONTROLLED STUDY; EXON; NERVOUS SYSTEM DEVELOPMENT; NONHUMAN; PRIORITY JOURNAL; RNA BINDING; VERTEBRATE; ANIMAL; BRAIN; CHICKEN; COMPARATIVE STUDY; EMBRYOLOGY; EMBRYONIC STEM CELL; EVOLUTION; GENETICS; HEK293 CELL LINE; HUMAN; METABOLISM; MOUSE; NEURAL STEM CELL;

MAMMALIA; VERTEBRATA;

ALTERNATIVE SPLICING; ANIMALS; BIOLOGICAL EVOLUTION; BRAIN; CHICKENS; EMBRYONIC STEM CELLS; EXONS; HEK293 CELLS; HETEROGENEOUS-NUCLEAR RIBONUCLEOPROTEINS; HUMANS; MICE; NEURAL STEM CELLS; NEUROGENESIS; POLYPYRIMIDINE TRACT-BINDING PROTEIN;

EID: 84939856392     PISSN: 00368075     EISSN: 10959203     Source Type: Journal    
DOI: 10.1126/science.aaa8381     Document Type: Article

References (20)

1. S. B. Carroll, Cell 134, 25-36 (2008).
2. C. P. Ponting, Nat. Rev. Genet. 9, 689-698 (2008).
3. A. Necsulea, H. Kaessmann, Nat. Rev. Genet. 15, 734-748 (2014).
4. N. L. Barbosa-Morais et al., Science 338, 1587-1593 (2012).
5. J. Merkin, C. Russell, P. Chen, C. B. Burge, Science 338, 1593-1599 (2012).
6. A. Reyes et al., Proc. Natl. Acad. Sci. U.S.A. 110, 15377-15382 (2013).
7. P. Kafasla et al., Biochem. Soc. Trans. 40, 815-820 (2012).
8. P. L. Boutz et al., Genes Dev. 21, 1636-1652 (2007).
9. M. Irimia et al., Cell 159, 1511-1523 (2014).
10. U. Braunschweig et al., Genome Res. 24, 1774-1786 (2014).
11. Y. I. Li, L. Sanchez-Pulido, W. Haerty, C. P. Ponting, Genome Res. 25, 1-13 (2015).
12. F. Robinson, C. W. Smith, J. Biol. Chem. 281, 800-806 (2006).
13. E. V. Makeyev, J. Zhang, M. A. Carrasco, T. Maniatis, Mol. Cell 27, 435-448 (2007).
14. Y. Xue et al., Cell 152, 82-96 (2013).
15. J. A. Calarco et al., Cell 138, 898-910 (2009).
16. B. Raj et al., Mol. Cell 56, 90-103 (2014).
17. D. Ray et al., Nature 499, 172-177 (2013).
18. M. Llorian et al., Nat. Struct. Mol. Biol. 17, 1114-1123 (2010).
19. A. Han et al., PLOS Comput. Biol. 10, e1003442 (2014).
20. Y. Xing, C. Lee, Nat. Rev. Genet. 7, 499-509 (2006).