Hepatitis Delta co-infection in humanized mice leads to pronounced induction of innate immune responses in comparison to HBV mono-infection

Journal of Hepatology

Volumn 63, Issue 2, 2015, Pages 346-353

  Giersch, Katja ^a   Allweiss, Lena ^a   Volz, Tassilo ^a   Helbig, Martina ^a   Bierwolf, Jeanette ^b   Lohse, Ansgar W ^a,c   Pollok, Joerg M ^b   Petersen, Joerg ^d   Dandri, Maura ^a,c   Lütgehetmann, Marc ^a  

^a UNIVERSITY MEDICAL CENTER HAMBURG EPPENDORF   (Germany)

^b UNIVERSITY HOSPITAL BONN   (Germany)

^c German Center for Infection Research (DZIF)   (Germany)

^d DEPARTMENT OF CARDIOLOGY   (Germany)

Author keywords

Chronic viral hepatitis; HBV; HDV; ISG; uPA mice

Indexed keywords

HEPATITIS B CORE ANTIGEN; CYTOKINE RECEPTOR; IP10-MIG RECEPTOR;

ANIMAL TISSUE; ANTIGEN PRESENTATION; ARTICLE; CELLULAR DISTRIBUTION; DELTA AGENT HEPATITIS; GENE EXPRESSION; HEPATITIS B; HEPATITIS B VIRUS; HUMAN; HUMAN CELL; INFECTION; INFLAMMATION; INNATE IMMUNITY; LIVER CELL; LIVER INJURY; MIXED INFECTION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; VIRION; ANIMAL; COMPARATIVE STUDY; COMPLICATION; DISEASE MODEL; ENZYME LINKED IMMUNOSORBENT ASSAY; GENETICS; HEPATITIS DELTA VIRUS; IMMUNOLOGY; METABOLISM; PATHOLOGY; REAL TIME POLYMERASE CHAIN REACTION; SCID MOUSE; VIROLOGY; VIRUS LOAD;

ANIMALS; COINFECTION; DISEASE MODELS, ANIMAL; ENZYME-LINKED IMMUNOSORBENT ASSAY; HEPATITIS B VIRUS; HEPATITIS B, CHRONIC; HEPATITIS D, CHRONIC; HEPATITIS DELTA VIRUS; HEPATOCYTES; HUMANS; IMMUNITY, INNATE; MICE; MICE, SCID; REAL-TIME POLYMERASE CHAIN REACTION; RECEPTORS, CYTOKINE; VIRAL LOAD;

EID: 84939792698     PISSN: 01688278     EISSN: 16000641     Source Type: Journal    
DOI: 10.1016/j.jhep.2015.03.011     Document Type: Article

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