Protection of Quercetin against Triptolide-induced apoptosis by suppressing oxidative stress in rat Leydig cells

Chemico-Biological Interactions

Volumn 240, Issue , 2015, Pages 38-46

  Hu, Jie ^a   Yu, Qinwei ^a   Zhao, Fang ^a   Ji, Jinzi ^a,b   Jiang, Zhenzhou ^a   Chen, Xin ^a   Gao, Peng ^a   Ren, Yuran ^a   Shao, Shuai ^a   Zhang, Luyong ^a   Yan, Ming ^a  

^a CHINA PHARMACEUTICAL UNIVERSITY   (China)

^b NANJING MEDICAL UNIVERSITY   (China)

Author keywords

Apoptosis; Leydig cells; Nrf2; Oxidative stress; Quercetin; Triptolide

Indexed keywords

CASPASE 3; CASPASE 9; CYTOCHROME C; GLUTATHIONE PEROXIDASE; PROTEIN BAX; PROTEIN BCL 2; QUERCETIN; SUPEROXIDE DISMUTASE; TRANSCRIPTION FACTOR NRF2; TRIPTOLIDE; ANTIOXIDANT; DITERPENE; EPOXIDE; PHENANTHRENE DERIVATIVE; PROTECTIVE AGENT;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL PROTECTION; CELL VIABILITY; CONTROLLED STUDY; CYTOTOXICITY; DRUG EFFECT; DRUG MECHANISM; ENZYME ACTIVITY; LEYDIG CELL; MEMBRANE DEPOLARIZATION; MITOCHONDRIAL MEMBRANE POTENTIAL; NONHUMAN; OXIDATIVE STRESS; PROTEIN SECRETION; RAT; REPRODUCTIVE TOXICITY; ANIMAL; CELL SURVIVAL; CYTOLOGY; DRUG EFFECTS; HUMAN; MALE; POLYMERASE CHAIN REACTION; SPRAGUE DAWLEY RAT;

RATTUS;

ANIMALS; ANTIOXIDANTS; APOPTOSIS; CELL SURVIVAL; DITERPENES; EPOXY COMPOUNDS; HUMANS; LEYDIG CELLS; MALE; OXIDATIVE STRESS; PHENANTHRENES; POLYMERASE CHAIN REACTION; PROTECTIVE AGENTS; QUERCETIN; RATS; RATS, SPRAGUE-DAWLEY;

EID: 84939790512     PISSN: 00092797     EISSN: 18727786     Source Type: Journal    
DOI: 10.1016/j.cbi.2015.08.004     Document Type: Article

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