QUESTION 1: Does vitamin D supplementation prevent acute lower respiratory tract infections in children?

Archives of Disease in Childhood

Volumn 100, Issue 9, 2015, Pages 892-895

  Ali, Salma Rashid ^a   McDevitt, Helen ^a  

^a ROYAL HOSPITAL FOR SICK CHILDREN   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

VITAMIN D;

CASE REPORT; CHILD; CHILDHOOD DISEASE; COUGHING; CRACKLE; FEVER; HUMAN; LOWER RESPIRATORY TRACT INFECTION; LUNG AUSCULTATION; MALE; MEDICAL HISTORY; NOTE; PNEUMONIA; PRESCHOOL CHILD; PRIORITY JOURNAL; THORAX RADIOGRAPHY; VITAMIN D DEFICIENCY; VITAMIN SUPPLEMENTATION; ACUTE DISEASE; DIET SUPPLEMENTATION; EVIDENCE BASED MEDICINE; RESPIRATORY TRACT INFECTIONS;

ACUTE DISEASE; CHILD, PRESCHOOL; DIETARY SUPPLEMENTS; EVIDENCE-BASED MEDICINE; HUMANS; PNEUMONIA; RESPIRATORY TRACT INFECTIONS; VITAMIN D;

EID: 84939776005     PISSN: 00039888     EISSN: 14682044     Source Type: Journal    
DOI: 10.1136/archdischild-2015-308441     Document Type: Note

References (27)

1. Urashima M, Segawa T, Okazaki M, et al. Randomized trial of vitamin D supplementation to prevent seasonal influenza A in schoolchildren. Am J Clin Nutr 2010;91:1255-60.
2. Manaseki-Holland S, Qader G, Isaq Masher M, et al. Effects of vitamin D supplementation to children diagnosed with pneumonia in Kabul: a randomised controlled trial. Trop Med Int Health 2010;15:1148-55.
3. Majak P, Olszowiec-Chlebna M, Smejda K, et al. Vitamin D supplementation in children may prevent asthma exacerbation triggered by acute respiratory infection. J Allergy Clin Immunol 2011;127:1294-6.
4. Camargo CA Jr1, Ganmaa D, Frazier AL, et al. Randomized trial of vitamin D supplementation and risk of acute respiratory infection in Mongolia. Pediatrics 2012;130:e561-7.
5. Manaseki-Holland S, Maroof Z, Bruce J, et al. Effect on the incidence of pneumonia of vitamin D supplementation by quarterly bolus dose to infants in Kabul: a randomised controlled superiority trial. Lancet 2012;379:1419-27.
6. Manaseki-Holland S, Zulf Mughal M, Bhutta Z, et al. Vitamin D status of socio-economically deprived children in Kabul, Afghanistan. Int J Vitam Nutr Res 2008;78:16-20.
7. World Health Organisation. Technical bases for the WHO recommendations on the Management of Pneumonia in Children at First-Level Health facilities. Report No: WHO/ARI/91.20. Geneva: WHO, 1995.
8. WHO/UNICEF. Global action plan for prevention and control of pneumonia (GAPP). Geneva: World Health Organization, 2009.
9. McNally JD, Leis K, Matheson LA, et al. Vitamin D deficiency in young children with severe acute lower respiratory infection. Pediatric Pulmonol 2009;44:981-8.
10. Nair H, Nokes DJ, Gessner BD, et al. Global burden of acute lower respiratory infections due to respiratory syncytial virus in young children: a systematic review and meta-analysis. Lancet 2010;375:1545-55.
11. Roth DE, Shah R, Black RE, et al. Vitamin D status and acute lower respiratory infection in early childhood in Sylhet, Bangladesh. Acta Paediatrica 2010;99:389-93.
12. Wayse V, Yousafzai, Mogale K, et al. Association of subclinical vitamin D deficiency with severe acute lower respiratory infection in Indian children under 5 y. Eur J Clin Nutr 2004;58:563-7.
13. Roth DE, Jones AB, Prosser C, et al. Vitamin D receptor polymorphisms and the risk of acute lower respiratory tract infection in early childhood. J Infect Dis 2008;197:676-80.
14. Laaksi I, Ruohola JP, Tuohimaa P, et al. An association of serum vitamin D concentrations <40 nmol/L with acute respiratory tract infection in young Finnish men. Am J Clin Nutr 2007;86:714-17.
15. Belderbos ME, Houben B, Wilbrink E, et al. Cord blood vitamin D deficiency is associated with respiratory syncytial virus bronchiolitis. Pediatrics 2011;127:e1513-20.
16. Linday LA, Umhau JC, Shindledecker RD, et al. Cod liver oil, the ratio of vitamins A and D, frequent respiratory tract infections, and vitamin D deficiency in young children in the United States. Ann Otol Rhinol and Laryngol 2010;119:64-70.
17. Rockell JE, Green TJ, Skeaff CM, et al. Season and ethnicity are determinants of serum 25-hydroxyvitamin D concentrations in New Zealand children aged 5-14 y. J Nutr 2005;135:2602-8.
18. Ford L, Graham V, Wall A, et al. Vitamin D concentrations in a UK inner-city multicultural outpatient population. Ann Clin Biochem 2006;43:468-73.
19. Bhutta ZA. Vitamin D and child health: some emerging issues. Matern Child Nutr 2008;4:83-5.
20. Leikina E, Delanoe-Ayari H, Melikov K, et al. Carbohydrate-binding molecules inhibit viral fusion and entry by crosslinking membrane glycoproteins. Nat Immunol 2005;6:995-1001.
21. Ginde AA, Mansbach JM, Camargo CA Jr. Association between serum 25-hydroxyvitamin D level and upper respiratory tract infection in the Third National Health and Nutrition Examination Survey. Arch Intern Med 2009;169:384-90.
22. Arundel P, Ahmed SF, Allgrove J, et al. British Paediatric and Adolescent Bone Group. British Paediatric and Adolescent Bone Group's position statement on vitamin D deficiency. BMJ 2012;345:e8182.
23. Department of Health. Delivering a healthy start for pregnant women, new mums, babies and young children. London: Department of Health, 2010.
24. Royal College of Paediatrics and Child Health. Position statement on Vitamin D. 2012. http://www.rcpch.ac.uk/system/files/protected/page/vitdpositionstatement%20FINAL%2020121210.pdf
25. Vieth R, Chan PC, MacFarlene GD. Efficacy and safety of vitamin D3 intake exceeding the lowest observed dose adverse effect level. Am J Clin Nut 2001;73:288-94.
26. Nielsen NO, Skifte T, Andersson M, et al. Both high and low serum vitamin D concentrations are associated with tuberculosis: a case-control study in Greenland. Br J Nutr 2010;104:1487-91.
27. Vieth R. How to optimize vitamin D supplementation to prevent cancer: based on cellular adaptation and hydroxylase enzymology. Anticancer Res 2009;29:3675-84.