Comparative proteomic profile of the human umbilical cord blood exosomes between normal and preeclampsia pregnancies with high-resolution mass spectrometry

Cellular Physiology and Biochemistry

Volumn 36, Issue 6, 2015, Pages 2299-2306

  Jia, Ruizhe ^a   Li, Jingyun ^a   Rui, Can ^a   Ji, Hui ^a   Ding, Hongjuan ^a   Lu, Yuanqing ^a   De, Wei ^b   Sun, Lizhou ^c  

^a WOMEN S HOSPITAL OF NANJING MEDICAL UNIVERSITY   (China)

^b NANJING MEDICAL UNIVERSITY   (China)

^c THE FIRST AFFILIATED HOSPITAL OF NANJING MEDICAL UNIVERSITY   (China)

Author keywords

Exosomes; High resolution mass spectrometry; Preeclampsia; Proteomic profile; Umbilical cord blood

Indexed keywords

FIBRINOGEN; FIBRINOGEN ALPHA; PROTEIN S; UNCLASSIFIED DRUG; VON WILLEBRAND FACTOR; NANOPARTICLE; PROTEOME;

ADULT; ANALYTIC METHOD; ARTICLE; BINDING AFFINITY; BIOINFORMATICS; CHROMOSOME 4; COMPARATIVE STUDY; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DOWN REGULATION; ENZYME ACTIVITY; EXOSOME; FEMALE; HUMAN; HUMAN CELL; MASS SPECTROMETRY; NANOPARTICLE TRACKING ANALYSIS; PARTICLE SIZE; PREECLAMPSIA; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEOMICS; REGULATORY MECHANISM; UMBILICAL CORD BLOOD; UPREGULATION; BIOLOGY; BLOOD; FETUS BLOOD; GENE ONTOLOGY; HUMAN CHROMOSOME; LIQUID CHROMATOGRAPHY; METABOLISM; PATHOLOGY; PREGNANCY; PROCEDURES; PROTEIN PROTEIN INTERACTION; TANDEM MASS SPECTROMETRY;

ADULT; CHROMATOGRAPHY, LIQUID; CHROMOSOMES, HUMAN; COMPUTATIONAL BIOLOGY; EXOSOMES; FEMALE; FETAL BLOOD; GENE ONTOLOGY; HUMANS; NANOPARTICLES; PRE-ECLAMPSIA; PREGNANCY; PROTEIN INTERACTION MAPS; PROTEOME; PROTEOMICS; TANDEM MASS SPECTROMETRY;

EID: 84939621917     PISSN: 10158987     EISSN: 14219778     Source Type: Journal    
DOI: 10.1159/000430193     Document Type: Article

References (32)

1. English F-A, Kenny LC, McCarthy FP: Risk factors and effective management of preeclampsia. Integr Blood Press Control 2015;8:7-12.
2. Ouyang Y, Mouillet JF, Coyne CB, Sadovsky Y: Review: Placenta-specific micrornas in exosomes - good things come in nano-packages. Placenta 2014;35:S69-73.
3. Redman C-W, Sargent IL: Microparticles and immunomodulation in pregnancy and pre-eclampsia. J Reprod Immunol 2007;76:61-67.
4. Taylor D-D, Akyol S, Gercel-Taylor C: Pregnancy-associated exosomes and their modulation of t cell signaling. J Immunol 2006;176:1534-1542.
5. Vargas A, Zhou S, Ethier-Chiasson M, Flipo D, Lafond J, Gilbert C, Barbeau B: Syncytin proteins incorporated in placenta exosomes are important for cell uptake and show variation in abundance in serum exosomes from patients with preeclampsia. FASEB J 2014;28:3703-3719.
6. Cocucci E, Racchetti G, Meldolesi J: Shedding microvesicles: Artefacts no more. Trends Cell Biol 2009;19:43-51.
7. Torregrosa P-P, Gutzeit C, Johansson S, Admyre C, Stenius F, Alm J, Scheynius A, Gabrielsson S: Differences in exosome populations in human breast milk in relation to allergic sensitization and lifestyle. Allergy 2014;69:463-471.
8. Caby M-P, Lankar D, Vincendeau-Scherrer C, Raposo G, Bonnerot C: Exosomal-like vesicles are present in human blood plasma. Int Immunol 2005;17:879-887.
9. Pisitkun T, Shen RF, Knepper MA: Identification and proteomic profiling of exosomes in human urine. Proc Natl Acad Sci U S A 2004;101:13368-13373.
10. Frydrychowicz M, Kolecka-Bednarczyk A, Madejczyk M, Yasar S, Dworacki G: Exosomes - structure, biogenesis and biological role in non-small-cell lung cancer. Scand J Immunol 2015;81:2-10.
11. Southcombe J, Tannetta D, Redman C, Sargent I: The immunomodulatory role of syncytiotrophoblast microvesicles. PLoS One 2011;6:e20245.
12. Kwon J-Y, Maeng YS, Kwon YG, Kim YH, Kang MH, Park YW: Decreased endothelial progenitor cells in umbilical cord blood in severe preeclampsia. Gynecol Obstet Invest 2007;64:103-108.
13. Yusuf K, Kamaluddeen M, Hasan SU, Al-Awad E, Finch RA, Akierman AR: Ionized calcium levels in umbilical cord blood of women with preeclampsia and normotensive pregnancies. J Matern Fetal Neonatal Med 2012;25:203-205.
14. Csorba R, Yilmaz A, Tsikouras P, Wieg C, Teichmann A, von Tempelhoff GF: Rheological parameters in the umbilical cord blood in moderate and severe forms of preeclampsia. Clin Hemorheol Microcirc 2013;55:391-401.
15. Faraji D-R, Ghanbari A, Asgharnia M, Kian M: Comparison of nucleated red blood cells in the umbilical cord of term neonates in healthy women and women with preeclampsia. Iran J Reprod Med 2013;11:25-30.
16. Miao Z-J, Chen M, Wu H, Ding HJ, Shi ZH: Comparative proteomic profile of the human placenta in normal and fetal growth restriction subjects. Cell Physiol Biochem 2014;34:1701-1710.
17. Wang F-Q, Wang L, Shi ZH, Liang GL: Comparative n-glycoproteomic and phosphoproteomic profiling of human placental plasma membrane between normal and preeclampsia pregnancies with high-resolution mass spectrometry. PLoS One 2013;8:e80480.
18. Wang F-Q, Shi ZH, Wang P, You W, Liang GL: Comparative proteome profile of human placenta from normal and preeclamptic pregnancies. PLoS One 2013;8:e78025.
19. Shi Z-H, Long W, Zhao C, Guo XR, Shen R, Ding HJ: Comparative proteomics analysis suggests that placental mitochondria are involved in the development of pre-eclampsia. PLoS One 2013;8:e64351.
20. Jia R-Z, Ding GC, Gu CM, Huang T, Rui C, Wang YX, Lu Q: Cdx2 enhances htr-8/svneo trophoblast cell invasion by altering the expression of matrix metalloproteinases. Cell Physiol Biochem 2014;34:628-636.
21. Liu L, Zhang X, Rong C, Rui C, Ji H, Qian YJ, Jia RZ, Sun LZ: Distinct DNA methylomes of human placentas between pre-eclampsia and gestational diabetes mellitus. Cell Physiol Biochem 2014;34:1877-1889.
22. Lokossou A-G, Toudic C, Barbeau B: Implication of human endogenous retrovirus envelope proteins in placental functions. Viruses 2014;6:4609-4627.
23. Fox M-J, Gao H, Smith-Kinnaman WR, Liu Y, Mosley AL: The exosome component rrp6 is required for rna polymerase ii termination at specific targets of the nrd1-nab3 pathway. PLoS Genet 2015;10:e1004999.
24. Yamaguchi T, Izumi Y, Nakamura Y, Yamazaki T, Shiota M, Sano S, Tanaka M, Osada-Oka M, Shimada K, Miura K, Yoshiyama M, Iwao H: Repeated remote ischemic conditioning attenuates left ventricular remodeling via exosome-mediated intercellular communication on chronic heart failure after myocardial infarction. Int J Cardiol 2015;178:239-246.
25. Zhang J, Li S, Li L, Li M, Guo CY, Yao J, Mi SL: Exosome and exosomal microrna: Trafficking, sorting, and function. Genomics Proteomics Bioinformatics 2015;13:17-24.
26. Kuntz T-B, Christensen RD, Stegner J, Duff P, Koenig JM: Fas and fas ligand expression in maternal blood and in umbilical cord blood in preeclampsia. Pediatr Res 2001;50:743-749.
27. Galewska Z, Romanowicz L, Jaworski S, Bankowski E: Gelatinase matrix metalloproteinase (mmp)-2 and mmp-9 of the umbilical cord blood in preeclampsia. Clin Chem Lab Med 2008;46:517-522.
28. Tuten A, Erman H, Korkmaz GG, Oncul M, Gelisgen R, Sozer V, Acikgoz S, Simsek G, Uzun H: Comparison of maternal and umbilical cord blood soluble lectin-like oxidized low-density lipoprotein receptor 1 levels in early- and late-onset preeclampsia. Arch Gynecol Obstet 2014;290:1007-1013.
29. Yusuf K, Wilson RD, Kamaluddeen M, Franta J, Hasan SU, Akierman A: Methemoglobin levels in umbilical cord blood of women with intrauterine growth restriction and preeclampsia. J Matern Fetal Neonatal Med 2014;27:789-794.
30. Aref S, Goda H: Increased vwf antigen levels and decreased adamts13 activity in preeclampsia. Hematology 2013;18:237-241.
31. Wen Q, Liu LY, Yang T, Alev C, Wu S, Stevenson DK, Sheng G, Butte AJ, Ling XB: Peptidomic identification of serum peptides diagnosing preeclampsia. PLoS One 2013;8:e65571.
32. Dahlback B: C4b-binding protein: A forgotten factor in thrombosis and hemostasis. Semin Thromb Hemost 2011;37:355-361.