-
1
-
-
84876909069
-
The ageing haematopoietic stem cell compartment
-
Geiger, H., de Haan, G. & Florian, M. C. The ageing haematopoietic stem cell compartment. Nat. Rev. Immunol. 13, 376-389 (2013).
-
(2013)
Nat. Rev. Immunol
, vol.13
, pp. 376-389
-
-
Geiger, H.1
De Haan, G.2
Florian, M.C.3
-
2
-
-
47049099198
-
A new mechanism for the aging of hematopoietic stem cells: Aging changes the clonal composition of the stem cell compartment but not individual stem cells
-
Cho, R. H., Sieburg, H. B. & Muller-Sieburg, C. E. A new mechanism for the aging of hematopoietic stem cells: aging changes the clonal composition of the stem cell compartment but not individual stem cells. Blood 111, 5553-5561 (2008).
-
(2008)
Blood
, vol.111
, pp. 5553-5561
-
-
Cho, R.H.1
Sieburg, H.B.2
Muller-Sieburg, C.E.3
-
3
-
-
84857873445
-
Hematopoietic stem cell subtypes expand differentially during development and display distinct lymphopoietic programs
-
Benz, C. et al. Hematopoietic stem cell subtypes expand differentially during development and display distinct lymphopoietic programs. Cell Stem Cell 10, 273-283 (2012).
-
(2012)
Cell Stem Cell
, vol.10
, pp. 273-283
-
-
Benz, C.1
-
4
-
-
84886924368
-
Heterogeneity of young and aged murine hematopoietic stem cells revealed by quantitative clonal analysis using cellular barcoding
-
Verovskaya, E. et al. Heterogeneity of young and aged murine hematopoietic stem cells revealed by quantitative clonal analysis using cellular barcoding. Blood 122, 523-532 (2013).
-
(2013)
Blood
, vol.122
, pp. 523-532
-
-
Verovskaya, E.1
-
5
-
-
0033526067
-
Bone morphogenetic proteins regulate the developmental program of human hematopoietic stem cells
-
Bhatia, M. et al. Bone morphogenetic proteins regulate the developmental program of human hematopoietic stem cells. J. Exp. Med. 189, 1139-1148 (1999).
-
(1999)
J. Exp. Med
, vol.189
, pp. 1139-1148
-
-
Bhatia, M.1
-
6
-
-
0242363225
-
Identification of the haematopoietic stem cell niche and control of the niche size
-
Zhang, J. et al. Identification of the haematopoietic stem cell niche and control of the niche size. Nature 425, 836-841 (2003).
-
(2003)
Nature
, vol.425
, pp. 836-841
-
-
Zhang, J.1
-
7
-
-
77954704813
-
Canonical BMP signaling is dispensable for hematopoietic stem cell function in both adult and fetal liver hematopoiesis, but essential to preserve colon architecture
-
Singbrant, S. et al. Canonical BMP signaling is dispensable for hematopoietic stem cell function in both adult and fetal liver hematopoiesis, but essential to preserve colon architecture. Blood 115, 4689-4698 (2010).
-
(2010)
Blood
, vol.115
, pp. 4689-4698
-
-
Singbrant, S.1
-
8
-
-
84907896951
-
SMAD signaling regulates CXCL12 expression in the bone marrow niche, affecting homing and mobilization of hematopoietic progenitors
-
Khurana, S. et al. SMAD signaling regulates CXCL12 expression in the bone marrow niche, affecting homing and mobilization of hematopoietic progenitors. Stem Cells 32, 3012-3022 (2014).
-
(2014)
Stem Cells
, vol.32
, pp. 3012-3022
-
-
Khurana, S.1
-
9
-
-
50849113091
-
Real time monitoring of BMP Smads transcriptional activity during mouse development
-
Monteiro, R. M. et al. Real time monitoring of BMP Smads transcriptional activity during mouse development. Genesis. 46, 335-346 (2008).
-
(2008)
Genesis
, vol.46
, pp. 335-346
-
-
Monteiro, R.M.1
-
10
-
-
38049138738
-
Embryonic stromal clones reveal developmental regulators of definitive hematopoietic stem cells
-
Durand, C. et al. Embryonic stromal clones reveal developmental regulators of definitive hematopoietic stem cells. Proc. Natl Acad. Sci. USA 104, 20838-20843 (2007).
-
(2007)
Proc. Natl Acad. Sci. USA
, vol.104
, pp. 20838-20843
-
-
Durand, C.1
-
11
-
-
84872485255
-
The biochemistry of hematopoietic stem cell development
-
Kaimakis, P., Crisan, M. & Dzierzak, E. The biochemistry of hematopoietic stem cell development. Biochim. Biophys. Acta 1830, 2395-2403 (2013).
-
(2013)
Biochim. Biophys. Acta
, vol.1830
, pp. 2395-2403
-
-
Kaimakis, P.1
Crisan, M.2
Dzierzak, E.3
-
12
-
-
0034663048
-
Polarized expression of bone morphogenetic protein-4 in the human aorta-gonad-mesonephros region
-
Marshall, C. J., Kinnon, C. & Thrasher, A. J. Polarized expression of bone morphogenetic protein-4 in the human aorta-gonad-mesonephros region. Blood 96, 1591-1593 (2000).
-
(2000)
Blood
, vol.96
, pp. 1591-1593
-
-
Marshall, C.J.1
Kinnon, C.2
Thrasher, A.J.3
-
13
-
-
84858286273
-
Stalk cell phenotype depends on integration of Notch and Smad1/5 signaling cascades
-
Moya, I. M. et al. Stalk cell phenotype depends on integration of Notch and Smad1/5 signaling cascades. Dev. Cell 22, 501-514 (2012).
-
(2012)
Dev. Cell
, vol.22
, pp. 501-514
-
-
Moya, I.M.1
-
14
-
-
0036285647
-
Hematopoietic stem cells localize to the endothelial cell layer in the midgestation mouse aorta
-
de Bruijn, M. F. et al. Hematopoietic stem cells localize to the endothelial cell layer in the midgestation mouse aorta. Immunity 16, 673-683 (2002).
-
(2002)
Immunity
, vol.16
, pp. 673-683
-
-
De Bruijn, M.F.1
-
15
-
-
34547174800
-
Functional identification of the hematopoietic stem cell niche in the ventral domain of the embryonic dorsal aorta
-
Taoudi, S. & Medvinsky, A. Functional identification of the hematopoietic stem cell niche in the ventral domain of the embryonic dorsal aorta. Proc. Natl Acad. Sci. USA 104, 9399-9403 (2007).
-
(2007)
Proc. Natl Acad. Sci. USA
, vol.104
, pp. 9399-9403
-
-
Taoudi, S.1
Medvinsky, A.2
-
16
-
-
78049326155
-
Three-dimensional cartography of hematopoietic clusters in the vasculature of whole mouse embryos
-
Yokomizo, T. & Dzierzak, E. Three-dimensional cartography of hematopoietic clusters in the vasculature of whole mouse embryos. Development 137, 3651-3661 (2010).
-
(2010)
Development
, vol.137
, pp. 3651-3661
-
-
Yokomizo, T.1
Dzierzak, E.2
-
17
-
-
84889568419
-
SLAM family markers resolve functionally distinct subpopulations of hematopoietic stem cells and multipotent progenitors
-
Oguro, H., Ding, L. & Morrison, S. J. SLAM family markers resolve functionally distinct subpopulations of hematopoietic stem cells and multipotent progenitors. Cell Stem Cell 13, 102-116 (2013).
-
(2013)
Cell Stem Cell
, vol.13
, pp. 102-116
-
-
Oguro, H.1
Ding, L.2
Morrison, S.J.3
-
18
-
-
34548601610
-
Haematopoietic stem cells do not asymmetrically segregate chromosomes or retain BrdU
-
Kiel, M. J. et al. Haematopoietic stem cells do not asymmetrically segregate chromosomes or retain BrdU. Nature 449, 238-242 (2007).
-
(2007)
Nature
, vol.449
, pp. 238-242
-
-
Kiel, M.J.1
-
19
-
-
84893796026
-
Clonal expansion capacity defines two consecutive developmental stages of long-term hematopoietic stem cells
-
Grinenko, T. et al. Clonal expansion capacity defines two consecutive developmental stages of long-term hematopoietic stem cells. J. Exp. Med. 211, 209-215 (2014).
-
(2014)
J. Exp. Med
, vol.211
, pp. 209-215
-
-
Grinenko, T.1
-
20
-
-
77449145533
-
Distinct hematopoietic stem cell subtypes are differentially regulated by TGF-beta1
-
Challen, G. A., Boles, N. C., Chambers, S. M. & Goodell, M. A. Distinct hematopoietic stem cell subtypes are differentially regulated by TGF-beta1. Cell Stem Cell 6, 265-278 (2010).
-
(2010)
Cell Stem Cell
, vol.6
, pp. 265-278
-
-
Challen, G.A.1
Boles, N.C.2
Chambers, S.M.3
Goodell, M.A.4
-
21
-
-
56549084319
-
Hematopoietic stem cell function and survival depend on c-Myc and N-Myc activity
-
Laurenti, E. et al. Hematopoietic stem cell function and survival depend on c-Myc and N-Myc activity. Cell Stem Cell 3, 611-624 (2008).
-
(2008)
Cell Stem Cell
, vol.3
, pp. 611-624
-
-
Laurenti, E.1
-
22
-
-
84905967192
-
STAT5 in hematopoietic stem cell biology and transplantation
-
Wang, Z. & Bunting, K. D. STAT5 in hematopoietic stem cell biology and transplantation. JAKSTAT 2, e27159 (2013).
-
(2013)
JAKSTAT
, vol.2
, pp. e27159
-
-
Wang, Z.1
Bunting, K.D.2
-
23
-
-
84856911269
-
A novel murine model of myeloproliferative disorders generated by overexpression of the transcription factor NF-E2
-
Kaufmann, K. B. et al. A novel murine model of myeloproliferative disorders generated by overexpression of the transcription factor NF-E2. J. Exp. Med. 209, 35-50 (2012).
-
(2012)
J. Exp. Med
, vol.209
, pp. 35-50
-
-
Kaufmann, K.B.1
-
24
-
-
84902124364
-
A crucial role for the ubiquitously expressed transcription factor Sp1 at early stages of hematopoietic specification
-
Gilmour, J. et al. A crucial role for the ubiquitously expressed transcription factor Sp1 at early stages of hematopoietic specification. Development 141, 2391-2401 (2014).
-
(2014)
Development
, vol.141
, pp. 2391-2401
-
-
Gilmour, J.1
-
25
-
-
84882436729
-
Deletion of the NF-kappaB subunit p65/RelA in the hematopoietic compartment leads to defects in hematopoietic stem cell function
-
Stein, S. J. & Baldwin, A. S. Deletion of the NF-kappaB subunit p65/RelA in the hematopoietic compartment leads to defects in hematopoietic stem cell function. Blood 121, 5015-5024 (2013).
-
(2013)
Blood
, vol.121
, pp. 5015-5024
-
-
Stein, S.J.1
Baldwin, A.S.2
-
26
-
-
34548208677
-
Aging hematopoietic stem cells decline in function and exhibit epigenetic dysregulation
-
Chambers, S. M. et al. Aging hematopoietic stem cells decline in function and exhibit epigenetic dysregulation. PLoS Biol. 5, e201 (2007).
-
(2007)
PLoS Biol
, vol.5
, pp. e201
-
-
Chambers, S.M.1
-
27
-
-
33847375991
-
Epidemiology of hematological malignancies
-
Rodriguez-Abreu, D., Bordoni, A. & Zucca, E. Epidemiology of hematological malignancies. Ann. Oncol. 18(Suppl 1): i3-i8 (2007).
-
(2007)
Ann. Oncol
, vol.18
, pp. i3-i8
-
-
Rodriguez-Abreu, D.1
Bordoni, A.2
Zucca, E.3
-
28
-
-
84903773686
-
The sonic hedgehog factor GLI1 imparts drug resistance through inducible glucuronidation
-
Zahreddine, H. A. et al. The sonic hedgehog factor GLI1 imparts drug resistance through inducible glucuronidation. Nature 511, 90-93 (2014).
-
(2014)
Nature
, vol.511
, pp. 90-93
-
-
Zahreddine, H.A.1
-
29
-
-
79959418692
-
Three-dimensional imaging of whole midgestation murine embryos shows an intravascular localization for all hematopoietic clusters
-
Yokomizo, T., Ng, C. E., Osato, M. & Dzierzak, E. Three-dimensional imaging of whole midgestation murine embryos shows an intravascular localization for all hematopoietic clusters. Blood 117, 6132-6134 (2011).
-
(2011)
Blood
, vol.117
, pp. 6132-6134
-
-
Yokomizo, T.1
Ng, C.E.2
Osato, M.3
Dzierzak, E.4
-
30
-
-
16644386194
-
Hematopoietic stem cell enrichment from the AGM region of the mouse embryo
-
Robin, C. & Dzierzak, E. Hematopoietic stem cell enrichment from the AGM region of the mouse embryo. Methods Mol. Med. 105, 257-272 (2005).
-
(2005)
Methods Mol. Med
, vol.105
, pp. 257-272
-
-
Robin, C.1
Dzierzak, E.2
-
31
-
-
84864880991
-
Full-length mRNA-Seq from single-cell levels of RNA and individual circulating tumor cells
-
Ramskold, D. et al. Full-length mRNA-Seq from single-cell levels of RNA and individual circulating tumor cells. Nat. Biotechnol. 30, 777-782 (2012).
-
(2012)
Nat. Biotechnol
, vol.30
, pp. 777-782
-
-
Ramskold, D.1
-
32
-
-
84859885816
-
Differential gene and transcript expression analysis of RNAseq experiments with TopHat and Cufflinks
-
Trapnell, C. et al. Differential gene and transcript expression analysis of RNAseq experiments with TopHat and Cufflinks. Nat. Protoc. 7, 562-578 (2012).
-
(2012)
Nat. Protoc
, vol.7
, pp. 562-578
-
-
Trapnell, C.1
-
33
-
-
84876100615
-
Enrichr: Interactive and collaborative HTML5 gene list enrichment analysis tool
-
Chen, E. Y. et al. Enrichr: interactive and collaborative HTML5 gene list enrichment analysis tool. BMC Bioinformatics 14, 128 (2013).
-
(2013)
BMC Bioinformatics
, vol.14
, pp. 128
-
-
Chen, E.Y.1
|