Evidence that bacteriophage λ Kil peptide inhibits bacterial cell division by disrupting FtsZ protofilaments and sequestering protein subunits

Journal of Biological Chemistry

Volumn 290, Issue 33, 2015, Pages 20325-20335

  Hernández Rocamora, Víctor M ^a,c   Alfonso, Carlos ^a   Margolin, William ^b   Zorrilla, Silvia ^a   Rivas, Germán ^a  

^a CENTRO DE INVESTIGACIONES BIOLÓGICAS   (Spain)

^b UNIVERSITY OF TEXAS MEDICAL SCHOOL   (United States)

^c NEWCASTLE UNIVERSITY   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIOPHAGES; CELL PROLIFERATION; ESCHERICHIA COLI; PEPTIDES; POLYMERIZATION; POLYMERS; PROTEINS; SITE SELECTION;

BACTERIAL CELL DIVISION; BACTERIAL INFECTIONS; BIOCHEMICAL METHODS; GTPASE ACTIVITY; INHIBITION MECHANISMS; MICROMOLAR RANGE; POLYMERIZATION REACTION; PROTEIN SUBUNITS;

ENZYME INHIBITION;

BACTERIAL PROTEIN; FTSZ PROTEIN; GUANOSINE 5' [(ALPHA,BETA)METHYLENO]TRIPHOSPHATE; GUANOSINE DERIVATIVE; GUANOSINE TRIPHOSPHATASE; KIL PEPTIDE; UNCLASSIFIED DRUG; BIOPOLYMER; CYTOSKELETON PROTEIN; FTSZ PROTEIN, BACTERIA; GUANOSINE TRIPHOSPHATE; PEPTIDE; VIRUS PROTEIN;

ANISOTROPY; ARTICLE; BACTERIAL CELL; BINDING AFFINITY; CYTOSKELETON; ENTEROBACTERIA PHAGE LAMBDA; ENZYME ACTIVITY; ENZYME INHIBITION; ESCHERICHIA COLI; FLUORESCENCE CORRELATION SPECTROSCOPY; MITOSIS INHIBITION; NONHUMAN; PRIORITY JOURNAL; PROTEIN ASSEMBLY; PROTEIN FUNCTION; PROTEIN POLYMERIZATION; PROTEIN PROTEIN INTERACTION; PROTEIN SECONDARY STRUCTURE; PROTEIN TERTIARY STRUCTURE; PROTOFILAMENT; SEDIMENTATION; ULTRACENTRIFUGATION; BACTERIUM; CELL DIVISION; CHEMISTRY; CYTOLOGY; PHYSIOLOGY;

BACTERIA (MICROORGANISMS); ENTEROBACTERIA PHAGE LAMBDA; ESCHERICHIA COLI;

BACTERIA; BACTERIAL PROTEINS; BACTERIOPHAGE LAMBDA; BIOPOLYMERS; CELL DIVISION; CYTOSKELETAL PROTEINS; GUANOSINE TRIPHOSPHATE; PEPTIDES; VIRAL PROTEINS;

EID: 84939613871     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M115.653329     Document Type: Article

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