Iohexol plasma clearance measurement in older adults with chronic kidney disease - Sampling time matters

Nephrology Dialysis Transplantation

Volumn 30, Issue 8, 2015, Pages 1307-1314

  Ebert, Natalie ^a   Loesment, Amina ^a   Martus, Peter ^b   Jakob, Olga ^a   Gaedeke, Jens ^a   Kuhlmann, Martin ^c   Bartel, Jan ^d   Schuchardt, Mirjam ^a   Tölle, Markus ^a   Huang, Tao ^a   Van Der Giet, Markus ^a   Schaeffner, Elke ^a  

^a CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^b UNIVERSITY OF TÜBINGEN   (Germany)

^c VIVANTES KLINIKUM IM FRIEDRICHSHAIN   (Germany)

^d Limbach Laboratory   (Germany)

Author keywords

24 hours iohexol clearance; elderly; GFR measurement protocol; measured GFR; reduced renal function

Indexed keywords

CREATININE; IOHEXOL; BIOLOGICAL MARKER; CONTRAST MEDIUM;

ACCURACY; AGED; ALBUMINURIA; ARTICLE; BLOOD LEVEL; CHRONIC KIDNEY DISEASE; COMPARATIVE STUDY; CROSS-SECTIONAL STUDY; DIABETES MELLITUS; FEMALE; GLOMERULUS FILTRATION RATE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HYPERTENSION; MAJOR CLINICAL STUDY; MALE; PLASMA CLEARANCE; PRIORITY JOURNAL; VERY ELDERLY; ADULT; BLOOD; CHRONIC KIDNEY FAILURE; COHORT ANALYSIS; KIDNEY FUNCTION TEST; LABORATORY DIAGNOSIS; METABOLISM; MIDDLE AGED; PATHOPHYSIOLOGY; TIME; TISSUE DISTRIBUTION;

ADULT; AGED; AGED, 80 AND OVER; BIOMARKERS; COHORT STUDIES; CONTRAST MEDIA; CREATININE; CROSS-SECTIONAL STUDIES; FEMALE; GLOMERULAR FILTRATION RATE; HUMANS; IOHEXOL; KIDNEY FUNCTION TESTS; MALE; MIDDLE AGED; RENAL INSUFFICIENCY, CHRONIC; SPECIMEN HANDLING; TIME FACTORS; TISSUE DISTRIBUTION;

EID: 84939613635     PISSN: 09310509     EISSN: 14602385     Source Type: Journal    
DOI: 10.1093/ndt/gfv116     Document Type: Article

References (36)

1. Gaspari F, Perico N, Remuzzi G. Application of newer clearance techniques for the determination of glomerular filtration rate. Curr Opin Nephrol Hypertens 1998; 7: 675-680
2. van Westen D, Almen T, Chai CM et al. Biliary and total extrarenal clearance of inulin and iohexol in pigs.Asource of error when determining gfr as body clearance. Nephron 2002; 91: 300-307
3. Olsson B, Aulie A, Sveen K et al. Human pharmacokinetics of iohexol. A new nonionic contrast medium. Invest Radiol 1983; 18: 177-182
4. Frennby B, Sterner G, Almen T et al. Determination of low glomerular filtration rate using iohexol clearance. Invest Radiol 1994; 29 (Suppl. 2): S234-S235
5. Aakhus T, Sommerfelt SC, Stormorken H et al. Tolerance and excretion of iohexol after intravenous injection in healthy volunteers. Preliminary report. Acta Radiol Suppl 1980; 362: 131-134
6. Back SE, Krutzen E, Nilsson-Ehle P. Contrast media as markers for glomerular filtration: a pharmacokinetic comparison of four agents. Scand J Clin Lab Invest 1988; 48: 247-253
7. Soveri I, Berg UB, Bjork J et al. Measuring GFR: a systematic review. Am J Kidney Dis 2014; 64: 411-424
8. Bird NJ, Peters C, Michell AR et al. Comparison of GFR measurements assessed fromsingle versusmultiple samples.AmJKidneyDis 2009; 54: 278-288
9. Schwartz GJ, Furth S, Cole SR et al. Glomerular filtration rate via plasma iohexol disappearance: pilot study for chronic kidney disease in children. Kidney Int 2006; 69: 2070-2077
10. Gaspari F, Perico N, Ruggenenti P et al. Plasma clearance of nonradioactive iohexol as a measure of glomerular filtration rate. J Am Soc Nephrol 1995; 6: 257-263
11. Brochner-Mortensen J. Asimple method for the determination of glomerular filtration rate. Scand J Clin Lab Invest 1972; 30: 271-274
12. Ng DK, Schwartz GJ, Jacobson LP et al. Universal GFR determination based on two time points during plasma iohexol disappearance. Kidney Int 2011; 80: 423-430
13. Nilsson-Ehle P. Iohexol clearance for the determination of glomerular filtration rate: 15 years' experience in clinical practice. eJIFCC 2002; 13. http//www.ifcc.org/ejifcc/vol13no12/1301200105.htm
14. Sterner G, Frennby B, Hultberg B, et al. Iohexol clearance for GFR-determination in renal failure-single or multiple plasma sampling? Nephrol Dial Transplant 1996; 11: 521-525
15. Agarwal R, Bills JE, Yigazu PM et al. Assessment of iothalamate plasma clearance: duration of study affects quality of GFR. Clin J Am Soc Nephrol 2009; 4: 77-85
16. Stolz A, Hoizey G, Toupance O et al. Evaluation of sample bias for measuring plasma iohexol clearance in kidney transplantation. Transplantation 2010; 89: 440-445
17. Jacobsson L. A method for the calculation of renal clearance based on a single plasma sample. Clin Physiol 1983; 3: 297-305
18. Schaeffner ES, Ebert N, Delanaye P et al. Two novel equations to estimate kidney function in persons aged 70 years or older. Ann Intern Med 2012; 157: 471-481
19. Schaeffner ES, van der Giet M, Gaedeke J et al. The Berlin initiative study: the methodology of exploring kidney function in the elderly by combining a longitudinal and cross-sectional approach. Eur J Epidemiol 2010; 25: 203-210
20. Cavalier E, Rozet E, Dubois N et al. Performance of iohexol determination in serum and urine by HPLC: validation, risk and uncertainty assessment. Clin Chim Acta 2008; 396: 80-85
21. Du Bois D, Du Bois E. A formula to estimate the approximate surface area if height and weight be known. Arch Intern Med 1916; 17: 863-871
22. Bland JM, Altman DG. Statistical methods for assessing agreement between two methods of clinical measurement. Lancet 1986; 1: 307-310
23. Levey AS, Stevens LA, Schmid CH et al. A new equation to estimate glomerular filtration rate. Ann Intern Med 2009; 150: 604-612
24. Levey AS, Bosch JP, Lewis JB et al. A more accurate method to estimate glomerular filtration rate from serum creatinine: a new prediction equation. Modification of diet in renal disease study group. Ann Intern Med 1999; 130: 461-470
25. Bjork J, Grubb A, SternerG et al. Revised equations for estimating glomerular filtration rate based on the Lund-Malmo Study cohort. Scand J Clin Lab Invest 2011; 71: 232-239
26. Cockcroft DW, Gault MH. Prediction of creatinine clearance from serum creatinine. Nephron 1976; 16: 31-41
27. Kilbride HS, Stevens PE, Eaglestone G et al. Accuracy of the MDRD (Modification of Diet in Renal Disease) Study and CKD-EPI (CKD Epidemiology Collaboration) equations for estimation of GFR in the elderly. AmJ Kidney Dis 2012; 61: 57-66
28. Van Pottelbergh G, Hoste L, Degryse J et al. Measuring the glomerular filtration rate in different age groups using iohexol, the protocol from the Belgian iohexol study. Clin Biochem 2013; 46: 31-36
29. Nyman U,Grubb A, Larsson A et al. The revised Lund-MalmoGFR estimating equation outperforms MDRD and CKD-EPI across GFR, age and BMI intervals in a large Swedish population. Clin Chem Lab Med 2013; 1-10
30. Lopes MB, Araujo LQ, Passos MT et al. Estimation of glomerular filtration rate from serum creatinine and cystatin C in octogenarians and nonagenarians. BMC Nephrol 2013; 14: 265
31. Gaspari F, Ruggenenti P, Porrini E et al. The GFR and GFR decline cannot be accurately estimated in type 2 diabetics. Kidney Int 2013; 84: 164-173
32. Lambers Heerspink HJ, Gansevoort RT, Brenner BM et al. Comparison of different measures of urinary protein excretion for prediction of renal events. J Am Soc Nephrol 2010; 21: 1355-1360
33. Fan L, Levey AS, Gudnason V et al. Comparing GFR Estimating Equations Using Cystatin C and Creatinine in Elderly Individuals. J Am Soc Nephrol 2014; doi: 10.1681/ASN.2014060607
34. Alshaer IM, KilbrideHS, Stevens PE et al. External validation of the Berlin equations for estimation of GFR in the elderly. Am J Kidney Dis 2014; 63: 862-865
35. VanAcker BA,KoomenGC, Arisz L.Drawbacks of the constant-infusion technique for measurement of renal function. Am J Physiol 1995; 268: F543-F552
36. Sirota JH, Baldwin DS, Villarreal H. Diurnal variations of renal function in man. J Clin Invest 1950; 29: 187-192