Generation and characterization of a protective mouse monoclonal antibody against human enterovirus 71

Applied Microbiology and Biotechnology

Volumn 99, Issue 18, 2015, Pages 7663-7671

  Deng, Yong Qiang ^a   Ma, Jie ^a   Xu, Li Juan ^a   Li, Yue Xiang ^a,b   Zhao, Hui ^a   Han, Jian Feng ^a   Tao, Jiang ^a   Li, Xiao Feng ^a   Zhu, Shun Ya ^a   Qin, E De ^a   Qin, Cheng Feng ^a,b  

^a BEIJING INSTITUTE OF MICROBIOLOGY AND EPIDEMIOLOGY   (China)

^b ANHUI MEDICAL UNIVERSITY   (China)

Author keywords

Human enterovirus 71; Neutralizing antibody; SP70 peptide; VP1 protein

Indexed keywords

AMINO ACIDS; MAMMALS; MONOCLONAL ANTIBODIES; PEPTIDES; PROTEINS; VIRUSES;

ALANINE-SCANNING MUTAGENESIS; AMINO ACID RESIDUES; ANTIVIRAL TREATMENTS; ENTEROVIRUS 71; MONOCLONAL ANTIBODIES (MABS); NATURAL INFECTION; NEUTRALIZING ANTIBODIES; THERAPEUTIC POTENTIALS;

ANTIBODIES;

EPITOPE; IMMUNOGLOBULIN M; MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY 2G8; PROTEIN VP1; UNCLASSIFIED DRUG; NEUTRALIZING ANTIBODY; PROTEIN BINDING; VIRUS ANTIBODY; VIRUS PROTEIN;

AMINO ACID; ANTIBODY; BIOASSAY; BIOCHEMISTRY; BIOTECHNOLOGY; MUTATION; NEUTRALIZATION; PROTEIN; PUBLIC HEALTH; RODENT; VACCINE;

ALANINE SCANNING MUTAGENESIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BIOCHEMICAL ANALYSIS; CONTROLLED STUDY; DRUG EFFICACY; DRUG MECHANISM; ENTEROVIRUS 71; ENTEROVIRUS INFECTION; EPITOPE MAPPING; FEMALE; HUMAN; HUMAN CELL; INFECTION CONTROL; MOUSE; MUTAGENESIS; NONHUMAN; REVERSE GENETICS; VIRUS MUTANT; VIRUS NEUTRALIZATION; AMINO ACID SUBSTITUTION; ANIMAL; DISEASE MODEL; DNA MUTATIONAL ANALYSIS; ENTEROVIRUS A; ENTEROVIRUS INFECTIONS; GENETICS; IMMUNE EVASION; IMMUNOLOGY; ISOLATION AND PURIFICATION; NEWBORN; PASSIVE IMMUNIZATION; SERODIAGNOSIS; SURVIVAL ANALYSIS;

HUMAN ENTEROVIRUS 71; MIRIDAE;

AMINO ACID SUBSTITUTION; ANIMALS; ANIMALS, NEWBORN; ANTIBODIES, MONOCLONAL; ANTIBODIES, NEUTRALIZING; ANTIBODIES, VIRAL; DISEASE MODELS, ANIMAL; DNA MUTATIONAL ANALYSIS; ENTEROVIRUS A, HUMAN; ENTEROVIRUS INFECTIONS; IMMUNE EVASION; IMMUNIZATION, PASSIVE; IMMUNOGLOBULIN M; MICE; NEUTRALIZATION TESTS; PROTEIN BINDING; REVERSE GENETICS; SURVIVAL ANALYSIS; VIRAL STRUCTURAL PROTEINS;

EID: 84939567170     PISSN: 01757598     EISSN: 14320614     Source Type: Journal    
DOI: 10.1007/s00253-015-6652-8     Document Type: Article

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