Doppler Ultrasound and Transient Elastography in Liver Transplant Patients for Noninvasive Evaluation of Liver Fibrosis in Comparison with Histology: A Prospective Observational Study

Digestive Diseases and Sciences

Volumn 60, Issue 9, 2015, Pages 2825-2831

  Lutz, H H ^a   Schroeter, B ^a   Kroy, D C ^a   Neumann, U ^a   Trautwein, C ^a   Tischendorf, J J W ^a  

^a UNIVERSITY HOSPITAL RWTH AACHEN   (Germany)

Author keywords

Cirrhosis; Doppler ultrasound; Elastography; Hepatic vein resistance index; Liver biopsy; Liver fibrosis; Liver transplantation; Noninvasive fibrosis diagnostic

Indexed keywords

ADULT; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; DIAGNOSTIC ACCURACY; DIAGNOSTIC TEST ACCURACY STUDY; DOPPLER ECHOGRAPHY; ELASTOGRAPHY; FEMALE; HEPATIC ARTERY; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; INTERMETHOD COMPARISON; LIVER BIOPSY; LIVER BLOOD FLOW; LIVER FIBROSIS; LIVER TRANSPLANTATION; LIVER VEIN; MALE; MIDDLE AGED; NON INVASIVE MEASUREMENT; OBSERVATIONAL STUDY; PORTAL VEIN; PRIORITY JOURNAL; PROSPECTIVE STUDY; SENSITIVITY AND SPECIFICITY; AGED; AREA UNDER THE CURVE; BIOPSY; COMPARATIVE STUDY; DOPPLER ULTRASONOGRAPHY; ECHOGRAPHY; LIVER; LIVER CIRRHOSIS; PATHOLOGY; PATHOPHYSIOLOGY; PREDICTIVE VALUE; RECEIVER OPERATING CHARACTERISTIC; VASCULAR RESISTANCE;

ADULT; AGED; AREA UNDER CURVE; BIOPSY; ELASTICITY IMAGING TECHNIQUES; FEMALE; HEPATIC ARTERY; HEPATIC VEINS; HUMANS; LIVER; LIVER CIRRHOSIS; LIVER TRANSPLANTATION; MALE; MIDDLE AGED; PORTAL VEIN; PREDICTIVE VALUE OF TESTS; PROSPECTIVE STUDIES; ROC CURVE; ULTRASONOGRAPHY, DOPPLER; VASCULAR RESISTANCE;

EID: 84939567118     PISSN: 01632116     EISSN: 15732568     Source Type: Journal    
DOI: 10.1007/s10620-015-3682-0     Document Type: Article

References (32)

1. Germani G, Hytiroglou P, Fotiadu A, Burroughs AK, Dhillon AP. Assessment of fibrosis and cirrhosis in liver biopsies: an update. Semin Liver Dis. 2011;31:82–90. Epub 02/24/2011.
2. Banff Working G, Demetris AJ, Adeyi O, et al. Liver biopsy interpretation for causes of late liver allograft dysfunction. Hepatology. 2006;44:489–501.
3. Firpi RJ, Abdelmalek MF, Soldevila-Pico C, et al. One-year protocol liver biopsy can stratify fibrosis progression in liver transplant recipients with recurrent hepatitis C infection. Liver Transpl. 2004;10:1240–1247.
4. Tanaka T, Therapondos G, Selzner N, Renner EL, Lilly LB. Serum aspartate aminotransferase levels and previous histopathological findings enable reduction of protocol liver biopsies after liver transplantation for hepatitis C. Can J Gastroenterol. 2013;27:131–136.
5. Lang M, Neumann UP, Muller AR, Bechstein WO, Neuhaus R, Neuhaus P. Komplikationen der perkutanen Leberbiopsie bei Patienten nach Lebertransplantation (Complications of percutaneous liver biopsy in patients after liver transplantation). Zeitschrift fur Gastroenterologie. 1999;37:205–208.
6. Castera L, Vergniol J, Foucher J, Le Bail B, Chanteloup E, Haaser M, et al. Prospective comparison of transient elastography, Fibrotest, APRI, and liver biopsy for the assessment of fibrosis in chronic hepatitis C. Gastroenterology. 2005;128:343–350. Epub 02/03/2005.
7. Verveer C, Zondervan PE, Ten Kate FJ, Hansen BE, Janssen HL, de Knegt RJ. Evaluation of transient elastography for fibrosis assessment compared with large biopsies in chronic hepatitis B and C. Liver Int. 2012;32:622–628. doi:10.1111/j.1478-3231.2011.02663.x.
8. Myers RP, Pomier-Layrargues G, Kirsch R, Pollett A, Beaton M, Levstik M, et al. Discordance in fibrosis staging between liver biopsy and transient elastography using the fibroscan XL probe. J Hepatol. 2012;56:564–570. doi:10.1016/j.jhep.2011.10.007.
9. Gaia S, Carenzi S, Barilli AL, Bugianesi E, Smedile A, Brunello F, et al. Reliability of transient elastography for the detection of fibrosis in non-alcoholic fatty liver disease and chronic viral hepatitis. J Hepatol. 2011;54:64–71. Epub 10/12/2010.
10. Harata M, Hashimoto S, Kawabe N, Nitta Y, Murao M, Nakano T, et al. Liver stiffness in extrahepatic cholestasis correlates positively with bilirubin and negatively with alanine aminotransferase. Hepatol Res. 2011;41:423–429. Epub 03/26/2011.
11. Millonig G, Reimann FM, Friedrich S, Fonouni H, Mehrabi A, Buchler MW, et al. Extrahepatic cholestasis increases liver stiffness (FibroScan) irrespective of fibrosis. Hepatology. 2008;48:1718–1723. Epub 10/07/2008.
12. Crespo G, Lens S, Gambato M, et al. Liver stiffness 1 year after transplantation predicts clinical outcomes in patients with recurrent hepatitis C. Am J Transpl. 2014;14:375–383.
13. Barrault C, Roudot-Thoraval F, Tran Van Nhieu J, et al. Non-invasive assessment of liver graft fibrosis by transient elastography after liver transplantation. Clin Res Hepatol Gastroenterol. 2013;37:347–352.
14. Coulden RA, Lomas DJ, Farman P, Britton PD. Doppler ultrasound of the hepatic veins: normal appearances. Clin Radiol. 1992;45:223–227. Epub 04/01/1992.
15. Lutz HH, Gassler N, Tischendorf FW, Trautwein C, Tischendorf JJ. Doppler ultrasound of hepatic blood flow for noninvasive evaluation of liver fibrosis compared with liver biopsy and transient elastography. Dig Dis Sci. 2012;57:2222–2230.
16. von Herbay A, Frieling T, Haussinger D. Association between duplex Doppler sonographic flow pattern in right hepatic vein and various liver diseases. J Clin Ultrasound. 2001;29:25–30. Epub 02/17/2001.
17. Bolondi L, Li Bassi S, Gaiani S, Zironi G, Benzi G, Santi V, et al. Liver cirrhosis: changes of Doppler waveform of hepatic veins. Radiology. 1991;178:513–516. Epub 02/01/1991.
18. Ohta M, Hashizume M, Kawanaka H, Akazawa K, Tomikawa M, Higashi H, et al. Prognostic significance of hepatic vein waveform by Doppler ultrasonography in cirrhotic patients with portal hypertension. Am J Gastroenterol. 1995;90:1853–1857. Epub 10/01/1995.
19. Kim MY, Baik SK, Park DH, Lim DW, Kim JW, Kim HS, et al. Damping index of Doppler hepatic vein waveform to assess the severity of portal hypertension and response to propranolol in liver cirrhosis: a prospective nonrandomized study. Liver Int Off J Int Assoc Study Liver. 2007;27:1103–1110. Epub 09/12/2007.
20. Sebastiani G, Halfon P, Castera L, Mangia A, Di Marco V, Pirisi M, et al. Comparison of three algorithms of non-invasive markers of fibrosis in chronic hepatitis C. Aliment Pharmacol Ther. 2012;35:92–104. doi:10.1111/j.1365-2036.2011.04897.x.
21. Abu-Yousef MM. Duplex Doppler sonography of the hepatic vein in tricuspid regurgitation. AJR Am J Roentgenol. 1991;156:79–83. Epub 01/01/1991.
22. Scheinfeld MH, Bilali A, Koenigsberg M. Understanding the spectral Doppler waveform of the hepatic veins in health and disease. Radiographics. 2009;29:2081–2098. Epub 11/21/2009.
23. Menghini G, Lauro G, Caraceni M. Some innovations in the technic of the one-second needle biopsy of the liver. Am J Gastroenterol. 1975;64:175–180. Epub 09/01/1975.
24. Desmet VJ, Gerber M, Hoofnagle JH, Manns M, Scheuer PJ. Classification of chronic hepatitis: diagnosis, grading and staging. Hepatology. 1994;19:1513–1520. Epub 06/01/1994.
25. Pedersen JF, Madsen LG, Larsen VA, Hamberg O, Horn T, Federspiel B, et al. A Doppler waveform index to characterize hepatic vein velocity pattern and evaluate hepatic fibrosis. J Clin Ultrasound. 2008;36:208–211. Epub 03/13/2008.
26. EASL. Clinical practice guidelines: Management of hepatitis C virus infection. J Hepatol. 2011;55:245–264. Epub 03/05/2011.
27. Beuers U, Kullak-Ublick GA, Pusl T, Rauws ER, Rust C. Medical treatment of primary sclerosing cholangitis: a role for novel bile acids and other (post-) transcriptional modulators? Clin Rev Allergy Immunol. 2009;36:52–61. Epub 08/30/2008.
28. Canbay A, Feldstein A, Kronenberger B, Schulze-Osthoff K, Bantel H. Zytokeratin-18 als Marker zur nichtinvasiven Diagnostik und Prognose akuter und chronischer Lebererkrankungen (Cytokeratin 18 as marker for non-invasive diagnosis and prognosis of acute and chronic liver diseases). Zeitschrift fur Gastroenterologie. 2014;52:290–295.
29. Waidmann O, Koberle V, Brunner F, Zeuzem S, Piiper A, Kronenberger B. Serum microRNA-122 predicts survival in patients with liver cirrhosis. PloS One. 2012;7:e45652.
30. Joka D, Wahl K, Moeller S, Schlue J, Vaske B, Bahr MJ, et al. Prospective biopsy-controlled evaluation of cell death biomarkers for prediction of liver fibrosis and nonalcoholic steatohepatitis. Hepatology. 2012;55:455–464. doi:10.1002/hep.24734.
31. Boursier J, de Ledinghen V, Zarski JP, Fouchard-Hubert I, Gallois Y, Oberti F, et al. Comparison of 8 diagnostic algorithms for liver fibrosis in hepatitis C: new algorithms are more precise and entirely non-invasive. Hepatology. 2011;55:58–67. doi:10.1002/hep.24654.
32. Bintintan A, Chira RI, Mircea PA. Non-invasive ultrasound-based diagnosis and staging of esophageal varices in liver cirrhosis a systematic review of the literature published in the third millennium. Med Ultrason. 2013;15:116–124.