Predictors of clinical outcomes in acute decompensated heart failure: Acute Study of Clinical Effectiveness of Nesiritide in Decompensated Heart Failure outcome models

American Heart Journal

Volumn 170, Issue 2, 2015, Pages 290-297.e1

  Khazanie, Prateeti ^a,b   Heizer, Gretchen M ^a   Hasselblad, Vic ^a   Armstrong, Paul W ^c   Califf, Robert M ^a,b   Ezekowitz, Justin ^c   Dickstein, Kenneth ^d   Levy, Wayne C ^e   McMurray, John J V ^f   Metra, Marco ^g   Wilson Tang, W H ^h   Teerlink, John R ⁱ   Voors, Adriaan A ^j   O'Connor, Christopher M ^a,b   Hernandez, Adrian F ^a,b   Starling, Randall ^h  

^a DUKE CLINICAL RESEARCH INSTITUTE   (United States)

^b DUKE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF ALBERTA   (Canada)

^d STAVANGER UNIVERSITY HOSPITAL   (Norway)

^e UNIVERSITY OF WASHINGTON MEDICAL CENTER   (United States)

^f UNIVERSITY OF GLASGOW   (United Kingdom)

^g UNIVERSITY OF BRESCIA   (Italy)

^h LERNER RESEARCH INSTITUTE   (United States)

ⁱ UNIVERSITY OF CALIFORNIA   (United States)

^j UNIVERSITY OF GRONINGEN   (Netherlands)

more..

Author keywords

[No Author keywords available]

Indexed keywords

NESIRITIDE; NITROGEN; PLACEBO; SODIUM; TEZOSENTAN; UREA; BRAIN NATRIURETIC PEPTIDE; NATRIURETIC FACTOR;

ACUTE HEART FAILURE; ADULT; AGED; ARTICLE; CARDIOVASCULAR MORTALITY; CLINICAL EFFECTIVENESS; CONTROLLED STUDY; DOUBLE BLIND PROCEDURE; DRUG EFFICACY; DRUG SAFETY; DYSPNEA; FEMALE; HEART INDEX; HEART LEFT VENTRICLE EJECTION FRACTION; HEMODIALYSIS; HOSPITAL ADMISSION; HOSPITAL READMISSION; HUMAN; LOGISTIC REGRESSION ANALYSIS; MAJOR CLINICAL STUDY; MALE; MEDICAL RECORD REVIEW; MIDDLE AGED; MULTICENTER STUDY; PREDICTOR VARIABLE; PRIORITY JOURNAL; PUBLICATION; RANDOMIZED CONTROLLED TRIAL; REST; RISK FACTOR; SCORING SYSTEM; SCREENING TEST; SODIUM BLOOD LEVEL; SYSTOLIC BLOOD PRESSURE; TREATMENT OUTCOME; UREA NITROGEN BLOOD LEVEL; ACUTE DISEASE; CAUSE OF DEATH; CLINICAL TRIAL; DRUG EFFECTS; EPIDEMIOLOGY; EUROPE; HEART FAILURE; HEART LEFT VENTRICLE FUNCTION; INTRAVENOUS DRUG ADMINISTRATION; MORTALITY; OUTCOME ASSESSMENT; PATHOPHYSIOLOGY; PHYSIOLOGY; PROCEDURES; RETROSPECTIVE STUDY; RISK ASSESSMENT; SOUTH AND CENTRAL AMERICA; SURVIVAL RATE; TRENDS; UNITED STATES;

ACUTE DISEASE; AGED; CAUSE OF DEATH; DOUBLE-BLIND METHOD; EUROPE; FEMALE; HEART FAILURE; HUMANS; INJECTIONS, INTRAVENOUS; LATIN AMERICA; MALE; MIDDLE AGED; NATRIURETIC AGENTS; NATRIURETIC PEPTIDE, BRAIN; OUTCOME ASSESSMENT (HEALTH CARE); PATIENT READMISSION; RETROSPECTIVE STUDIES; RISK ASSESSMENT; SURVIVAL RATE; UNITED STATES; VENTRICULAR FUNCTION, LEFT;

EID: 84939565487     PISSN: 00028703     EISSN: 10976744     Source Type: Journal    
DOI: 10.1016/j.ahj.2015.04.006     Document Type: Article

References (38)

1. A.L. Bui, T.B. Horwich, and G.C. Fonarow Epidemiology and risk profile of heart failure Nat Rev Cardiol 8 2011 30 41
2. V.L. Roger, A.S. Go, D.M. Lloyd-Jones, and et al. Heart Disease and Stroke Statistics - 2012 update: a report from the American Heart Association Circulation 125 2012 e2 e220
3. P.A. Heidenreich, N.M. Albert, L.A. Allen, and et al. Forecasting the impact of heart failure in the United States: a policy statement from the American Heart Association Circ Heart Fail 6 2013 606 619
4. G.M. Felker, J.D. Leimberger, R.M. Califf, and et al. Risk stratification after hospitalization for decompensated heart failure J Card Fail 10 2004 460 466
5. W.C. Levy, D. Mozaffarian, D.T. Linker, and et al. The Seattle Heart Failure Model: prediction of survival in heart failure Circulation 113 2006 1424 1433
6. S.J. Pocock, D. Wang, M.A. Pfeffer, and et al. Predictors of mortality and morbidity in patients with chronic heart failure Eur Heart J 27 2006 65 75
7. C.M. O'Connor, W.T. Abraham, N.M. Albert, and et al. Predictors of mortality after discharge in patients hospitalized with heart failure: an analysis from the Organized Program to Initiate Lifesaving Treatment in Hospitalized Patients with Heart Failure (OPTIMIZE-HF) Am Heart J 156 2008 662 673
8. H. Wedel, J.J. McMurray, M. Lindberg, and et al. Predictors of fatal and non-fatal outcomes in the Controlled Rosuvastatin Multinational Trial in Heart Failure (CORONA): incremental value of apolipoprotein A-1, high-sensitivity C-reactive peptide and N-terminal pro B-type natriuretic peptide Eur J Heart Fail 11 2009 281 291
9. C.M. O'Connor, V. Hasselblad, R.H. Mehta, and et al. Triage after hospitalization with advanced heart failure: the ESCAPE (Evaluation Study of Congestive Heart Failure and Pulmonary Artery Catheterization Effectiveness) risk model and discharge score J Am Coll Cardiol 55 2010 872 878
10. C.M. O'Connor, R.J. Mentz, G. Cotter, and et al. The PROTECT in-hospital risk model: 7-day outcome in patients hospitalized with acute heart failure and renal dysfunction Eur J Heart Fail 14 2012 605 612
11. J.G. Cleland, K. Chiswell, J.R. Teerlink, and et al. Predictors of postdischarge outcomes from information acquired shortly after admission for acute heart failure: a report from the Placebo-Controlled Randomized Study of the Selective A1 Adenosine Receptor Antagonist Rolofylline for Patients Hospitalized With Acute Decompensated Heart Failure and Volume Overload to Assess Treatment Effect on Congestion and Renal Function (PROTECT) Study Circ Heart Fail 7 2014 76 87
12. C.M. O'Connor, R.C. Starling, A.F. Hernandez, and et al. Effect of nesiritide in patients with acute decompensated heart failure N Engl J Med 365 2011 32 43
13. C. Enders Applied missing data analysis 2010 Guilford New York, NY
14. J.J. McMurray, J.R. Teerlink, G. Cotter, and et al. Effects of tezosentan on symptoms and clinical outcomes in patients with acute heart failure: the VERITAS randomized controlled trials JAMA 298 2007 2009 2019
15. J.R. Teerlink, J.J. McMurray, R.C. Bourge, and et al. Tezosentan in patients with acute heart failure: design of the Value of Endothelin Receptor Inhibition with Tezosentan in Acute heart failure Study (VERITAS) Am Heart J 150 2005 46 53
16. G.E. Soto, P.G. Jones, and J.A. Spertus Prism™: a Web-based framework for deploying predictive clinical models Comput Cardiol 31 2004 193 196
17. S.V. Arnold, C. Decker, H. Ahmad, and et al. Converting the informed consent from a perfunctory process to an evidence-based foundation for patient decision making Circ Cardiovasc Qual Outcomes 1 2008 21 28
18. R.A. Hayward, D.M. Kent, S. Vijan, and et al. Multivariable risk prediction can greatly enhance the statistical power of clinical trial subgroup analysis BMC Med Res Methodol 6 2006 18
19. L. Klein, B.M. Massie, J.D. Leimberger, and et al. Admission or changes in renal function during hospitalization for worsening heart failure predict postdischarge survival: results from the Outcomes of a Prospective Trial of Intravenous Milrinone for Exacerbations of Chronic Heart Failure (OPTIME-CHF) Circ Heart Fail 1 2008 25 33
20. M.R. Cowie, M. Komajda, T. Murray-Thomas, and et al. Prevalence and impact of worsening renal function in patients hospitalized with decompensated heart failure: results of the prospective outcomes study in heart failure (POSH) Eur Heart J 27 2006 1216 1222
21. R. Pfister, H. Diedrichs, A. Schiedermair, and et al. Prognostic impact of NT-proBNP and renal function in comparison to contemporary multi-marker risk scores in heart failure patients Eur J Heart Fail 10 2008 315 320
22. H.M. Krumholz, Y.T. Chen, V. Vaccarino, and et al. Correlates and impact on outcomes of worsening renal function in patients > or =65 years of age with heart failure Am J Cardiol 85 2000 1110 1113
23. C.M. O'Connor, D.J. Whellan, D. Wojdyla, and et al. Factors related to morbidity and mortality in patients with chronic heart failure with systolic dysfunction: the HF-ACTION predictive risk score model Circ Heart Fail 5 2012 63 71
24. C.W. Yancy, M. Lopatin, L.W. Stevenson, and et al. Clinical presentation, management, and in-hospital outcomes of patients admitted with acute decompensated heart failure with preserved systolic function: a report from the Acute Decompensated Heart Failure National Registry (ADHERE) Database J Am Coll Cardiol 47 2006 76 84
25. C.V. Leier, L. Dei Cas, and M. Metra Clinical relevance and management of the major electrolyte abnormalities in congestive heart failure: hyponatremia, hypokalemia, and hypomagnesemia Am Heart J 128 1994 564 574
26. K.D. Aaronson, J.S. Schwartz, T.M. Chen, and et al. Development and prospective validation of a clinical index to predict survival in ambulatory patients referred for cardiac transplant evaluation Circulation 95 1997 2660 2667
27. M.C. Chen, H.W. Chang, C.I. Cheng, and et al. Risk stratification of in-hospital mortality in patients hospitalized for chronic congestive heart failure secondary to non-ischemic cardiomyopathy Cardiology 100 2003 136 142
28. M. Gheorghiade, W.A. Gattis, C.M. O'Connor, and et al. Effects of tolvaptan, a vasopressin antagonist, in patients hospitalized with worsening heart failure: a randomized controlled trial JAMA 291 2004 1963 1971
29. M. Gheorghiade, W.T. Abraham, N.M. Albert, and et al. Relationship between admission serum sodium concentration and clinical outcomes in patients hospitalized for heart failure: an analysis from the OPTIMIZE-HF registry Eur Heart J 28 2007 980 988
30. M. Gheorghiade, J.S. Rossi, W. Cotts, and et al. Characterization and prognostic value of persistent hyponatremia in patients with severe heart failure in the ESCAPE Trial Arch Intern Med 167 2007 1998 2005
31. J. Rossi, M. Bayram, J.E. Udelson, and et al. Improvement in hyponatremia during hospitalization for worsening heart failure is associated with improved outcomes: insights from the Acute and Chronic Therapeutic Impact of a Vasopressin Antagonist in Chronic Heart Failure (ACTIV in CHF) trial Acute Card Care 9 2007 82 86
32. G.T. Jao, and J.R. Chiong Hyponatremia in acute decompensated heart failure: mechanisms, prognosis, and treatment options Clin Cardiol 33 2010 666 671
33. D.S. Lee, P.C. Austin, J.L. Rouleau, and et al. Predicting mortality among patients hospitalized for heart failure: derivation and validation of a clinical model JAMA 290 2003 2581 2587
34. G.C. Fonarow, J.T. Heywood, P.A. Heidenreich, and et al. Temporal trends in clinical characteristics, treatments, and outcomes for heart failure hospitalizations, 2002 to 2004: findings from Acute Decompensated Heart Failure National Registry (ADHERE) Am Heart J 153 2007 1021 1028
35. M. Gheorghiade, W.T. Abraham, N.M. Albert, and et al. Systolic blood pressure at admission, clinical characteristics, and outcomes in patients hospitalized with acute heart failure JAMA 296 2006 2217 2226
36. M.H. Drazner, J.E. Rame, L.W. Stevenson, and et al. Prognostic importance of elevated jugular venous pressure and a third heart sound in patients with heart failure N Engl J Med 345 2001 574 581
37. Institute of Medicine Crossing the quality chasm: a new health system for the twenty-first century 2001 National Academy Press Washington, DC
38. B. Ky, B. French, K. McCloskey, and et al. High-sensitivity ST2 for prediction of adverse outcomes in chronic heart failure Circ Heart Fail 4 2011 180 187