Production of novel biopolymers in plants: Recent technological advances and future prospects

Current Opinion in Biotechnology

Volumn 32, Issue , 2015, Pages 68-75

  Snell, Kristi D ^a   Singh, Vijay ^b   Brumbley, Stevens M ^b  

^a Metabolix Inc   (United States)

^b UNIVERSITY OF NORTH TEXAS   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIODEGRADABLE POLYMERS; BIOMOLECULES; BIOPOLYMERS; CHEMICAL CONTAMINATION; GENE EXPRESSION; METABOLISM; PLASTICS APPLICATIONS;

CARBON AVAILABILITY; COMMERCIAL APPLICATIONS; INDUSTRIAL MATERIALS; METABOLIC PATHWAYS; POLYHYDROXYALKANOATES; POLY[-3-HYDROXYBUTYRATE]; RENEWABLE SOURCES; TECHNOLOGICAL ADVANCES;

INDUSTRIAL PLANTS;

AMINO ACID; BIOPOLYMER; COLLAGEN; CYANOPHYCIN; ELASTIN; POLY(3 HYDROXYBUTYRIC ACID); POLYHYDROXYALKANOIC ACID; SILK; RECOMBINANT PROTEIN;

BIOTECHNOLOGICAL PRODUCTION; CARBON PARTITIONING; CARBON SOURCE; CELL ORGANELLE; CELLS BY BODY ANATOMY; GENE EXPRESSION; MONOCOT; NONHUMAN; PHOTOSYNTHESIS; PLANT BIOTECHNOLOGY; PLANT CELL; PRIORITY JOURNAL; PROMOTER REGION; REVIEW; TRANSGENE; ANIMAL; BIOSYNTHESIS; BIOTECHNOLOGY; GENETICS; HUMAN; METABOLISM; PLANT; PROCEDURES;

AMINO ACIDS; ANIMALS; BIOPOLYMERS; BIOTECHNOLOGY; HUMANS; PLANTS; RECOMBINANT PROTEINS;

EID: 84939547139     PISSN: 09581669     EISSN: 18790429     Source Type: Journal    
DOI: 10.1016/j.copbio.2014.11.005     Document Type: Review

References (61)

1. Venkatachalam P, Geetha N, Sangeetha P, Thulaseedharan A: Natural rubber producing plants: an overview. Afr J Biotechnol 2013, 12:1297-1310.
2. Van Beilen JB, Poirier Y: Plants as factories for bioplastics and other biomaterials. In Plant biotechnology and agriculture: prospects for the 21st century. Edited by Altman A, Hasegawa PM. Academic Press; 2012:481-494.
3. Somleva MN, Peoples OP, Snell KD: PHA bioplastics, biochemicals, and energy from crops. Plant Biotechnol J 2013, 11:233-252.
4. Snell KD, Peoples OP: PHA bioplastic: a value-added coproduct for biomass biorefineries. Biofuels Bioprod Bioref 2009, 3:456-467.
5. Peoples O, Sinskey A: Poly-beta-hydroxybutyrate (PHB) biosynthesis in Alcaligenes eutrophus H16. Identification and characterization of the PHB polymerase gene (phbC). J Biol Chem 1989, 264:15298-15303.
6. Peoples O, Sinskey A: Poly-beta-hydroxybutyrate biosynthesis in Alcaligenes eutrophus H16. Characterization of the genes encoding beta-ketothiolase and acetoacetyl-CoA reductase. J Biol Chem 1989, 264:15293-15297.
7. Schubert P, Steinbüchel A, Schlegel HG: Cloning of the Alcaligenes eutrophus genes for synthesis of poly-beta-hydroxybutyric acid (PHB) and synthesis of PHB in Escherichia coli. J Bacteriol 1988, 170:5837-5847.
8. Slater SC, Voige WH, Dennis DE: Cloning and expression in Escherichia coli of the Alcaligenes eutrophus H16 poly-bhydroxybutyrate biosynthetic pathway. J Bacteriol 1988, 170:4431-4436.
9. Poirier Y, Dennis DE, Klomparens K, Somerville C: Polyhydroxybutyrate, a biodegradable thermoplastic, produced in transgenic plants. Science 1992, 256:520-523.
10. Xing S, Poirier Y: The protein acetylome and the regulation of metabolism. Trends Plant Sci 2012, 17:423-430.
11. Langdale JA: C4 cycles: past, present, and future research on C4 photosynthesis. Plant Cell 2011, 23:3879-3892.
12. Poirier Y, Gruys KJ: Production of polyhydroxyalkanoates in transgenic plants. In Biopolymers: polyesters I-biological systems and biotechnological production. Edited by Doi Y, Steinbüchel A. Wiley-VCH; 2002:401-435.
13. Petrasovits LA, Zhao L, McQualter RB, Snell KD, Somleva MN, Patterson NA, Nielsen LK, Brumbley SM: Enhanced polyhydroxybutyrate production in transgenic sugarcane. Plant Biotechnol J 2012, 10:569-578.
14. Petrasovits LA, Purnell MP, Nielsen LK, Brumbley SM: Production of polyhydroxybutyrate in sugarcane. Plant Biotechnol J 2007, 5:162-172.
15. Purnell MP, Petrasovits LA, Nielsen LK, Brumbley SM: Spatiotemporal characterisation of polyhydroxybutyrate accumulation in sugarcane. Plant Biotechnol J 2007, 5:173-184.
16. Somleva MN, Snell KD, Beaulieu JJ, Peoples OP, Garrison BR, Patterson NA: Production of polyhydroxybutyrate in switchgrass, a value-added co-product in an important lignocellulosic biomass crop. Plant Biotechnol J 2008, 6:663-678.
17. Hattersley PW: Characterization of C-4 type leaf anatomy in grasses (Poaceae), mesophyll-bundle sheath area ratios. Ann Bot-London 1984, 53:163-179.
18. Petrasovits LA, McQualter RB, Gebbie LK, Blackman DM, Nielsen LK, Brumbley SM: Chemical inhibition of acetyl coenzyme A carboxylase as a strategy to increase polyhydroxybutyrate yields in transgenic sugarcane. Plant Biotechnol J 2013, 11:1146-1151.
19. McQualter R, Somleva M, Gebbie L, Li X, Petrasovits L, Snell K, Nielsen L, Brumbley S: Factors affecting polyhydroxybutyrate accumulation in mesophyll cells of sugarcane and switchgrass. BMC Biotechnol 2014, 14:83.
20. Suzuki Y, Kurano M, Arai Y, Nakashita H, Doi Y, Usami R, Horikoshi K, Yamaguchi I: Enzyme inhibitors to increase poly-3-hydroxybutyrate production by transgenic tobacco. Biosci Biotechnol Biochem 2002, 66:2537-2542.
21. Okamura E, Tomita T, Sawa R, Nishiyama M, Kuzuyama T: Unprecedented acetoacetyl-coenzyme A synthesizing enzyme of the thiolase superfamily involved in the mevalonate pathway. Proc Natl Acad Sci U S A 2010, 107:11265-11270.
22. McQualter RB, Petrasovits LA, Gebbie LK, Schweitzer D, Blackman D, Plan M, Hodson M, Riches J, Snell KD, Brumbley SM, Nielsen L: The use of an acetoacetyl-CoA synthase in place of a b-ketothiolase enhances poly-3-hydroxybutyrate production in sugarcane mesophyll cells. Plant Biotechnol J 2014 http://dx.doi.org/10.1111/pbi.12298. in press.
23. Frey PA, Hegeman AD: Chapter 14. Carbon-carbon condensation and cleavage. Enzymatic reaction mechanisms. Oxford University Press; 2007.
24. Biomass Advisors, 2010. Camelina aviation biofuels: Market opportunity and renewable energy report. Available at www.biomassadvisors.com/.
25. Malik MR, Yang W, Patterson N, Tang J, Wellinghoff RL, Preuss ML, Burkitt C, Sharma N, Ji Y, Jez JM, Peoples OP, Jaworski JG, Cahoon EB, Snell KD: Production of high levels of poly-3-hydroxybutyrate in plastids of Camelina sativa seeds. Plant Biotechnol J 2014 http://dx.doi.org/10.1111/pbi.12290. in press.
26. Houmiel KL, Slater S, Broyles D, Casagrande L, Colburn S, Gonzalez K, Mitsky TA, Reiser SE, Shah D, Taylor NB, Tran M, Valentin HE, Gruys KJ: Poly(beta-hydroxybutyrate) production in oilseed leukoplasts of Brassica napus. Planta 1999, 209:547-550.
27. Valentin HE, Broyles DL, Casagrande LA, Colburn SM, Creely WL, DeLaquil PA, Felton HM, Gonzalez KA, Houmiel KL, Lutke K, Mahadeo DA, Mitsky TA, Padgette SR, Reiser SE, Slater S, Stark DM, Stock RT, Stone DA, Taylor NB, Thorne GM, Tran M, Gruys K: PHA production, from bacteria to plants. Int J Biol Macromol 1999, 25:303-306.
28. Bohmert K, Balbo I, Kopka J, Mittendorf V, Nawrath C, Poirier Y, Tischendorf G, Trethewey RN, Willmitzer L: Transgenic Arabidopsis plants can accumulate polyhydroxybutyrate to up to 4% of their fresh weight. Planta 2000, 211:841-845.
29. Martínez-Andújar C, Ordiz MI, Huang Z, Nonogaki M, Beachy RN, Nonogaki H: Induction of 9-cis-epoxycarotenoid dioxygenase in Arabidopsis thaliana seeds enhances seed dormancy. Proc Natl Acad Sci USA 2011, 108:17225-17229.
30. Kourtz L, Dillon K, Daughtry S, Peoples OP, Snell KD: Chemically inducible expression of the PHB biosynthetic pathway in Arabidopsis. Transgenic Res 2007, 16:759-769.
31. Xing S, van Deenen N, Magliano P, Frahm L, Forestier E, Nawrath C, Schaller H, Gronover CS, Prüfer D, Poirier Y: ATP citrate lyase activity is post-translationally regulated by sink strength and impacts the wax, cutin and rubber biosynthetic pathways. Plant J 2014, 79:270-284.
32. Tilbrook K, Poirier Y, Gebbie L, Schenk PM, McQualter RB, Brumbley SM: Reduced peroxisomal citrate synthase activity increases substrate availability for polyhydroxyalkanoate biosynthesis in plant peroxisomes. Plant Biotechnol J 2014, 12:1044-1052.
33. Poirier Y, Dennis D, Klomparens K, Nawrath C, Somerville C: Perspectives on the production of polyhydroxyalkanoates in plants. FEMS Microbiol Rev 1992, 103:237-246.
34. Fatland BL, Nikolau BJ, Wurtele ES: Reverse genetic characterization of cytosolic acetyl-CoA generation by ATPcitrate lyase in Arabidopsis. Plant Cell 2005, 17:182-203.
35. Tilbrook K, Gebbie L, Schenk PM, Poirier Y, Brumbley SM: Peroxisomal polyhydroxyalkanoate biosynthesis is a promising strategy for bioplastic production in high biomass crops. Plant Biotechnol J 2011, 9:958-969.
36. Kopinke FD, Remmler M, Mackenzie K: Thermal decomposition of biodegradable polyesters-I: poly(b-hydroxybutyric acid). Polym Degrad Stabil 1996, 52:25-38.
37. Mullen CA, Boateng AA, Schweitzer D, Sparks K, Snell KD: Mild pyrolysis of P3HB/switchgrass blends for the production of bio-oil enriched with crotonic acid. J Anal Appl Pyrol 2014, 107:40-45.
38. Schweitzer D, Mullen CA, Boateng AA, Snell KD: Bio-based nbutanol prepared from poly-3-hydroxybutyrate: optimization of the reduction of n-butyl crotonate to n-butanol. Org Process Res Dev 2015 http://dx.doi.org/10.1021/op500156b. in press.
39. Schweitzer D, Snell KD: Acrylates via metathesis of crotonates. Org Process Res Dev 2015 http://dx.doi.org/10.1021/op5003006. in press.
40. Thai TQ, Wille M, Garcia-Gonzalez L, Sorgeloos P, Bossier P, De Schryver P: Poly-ß-hydroxybutyrate content and dose of the bacterial carrier for Artemia enrichment determine the performance of giant freshwater prawn larvae. Appl Microbiol Biotechnol 2014, 98:5205-5215.
41. Hauptmann V, Weichert N, Rakhimova M, Conrad U: Spider silks from plants - a challenge to create native-sized spidroins. Biotechnol J 2013, 8:1183-1192.
42. Hauptmann V, Weichert N, Menzel M, Knoch D, Paege N, Scheller J, Spohn U, Conrad U, Gils M: Native-sized spider silk proteins synthesized in planta via intein-based multimerization. Transgenic Res 2013, 22:369-377.
43. Weichert N, Hauptmann V, Menzel M, Schallau K, Gunkel P, Hertel TC, Pietzsch M, Spohn U, Conrad U: Transglutamination allows production and characterization of native-sized ELPylated spider silk proteins from transgenic plants. Plant Biotechnol J 2014, 12:265-275.
44. Gutierrez SP, Saberianfar R, Kohalmi SE, Menassa R: Protein body formation in stable transgenic tobacco expressing elastin-like polypeptide and hydrophobin fusion proteins. BMC Biotechnol 2013, 13:40.
45. Phan HT, Hause B, Hause G, Arcalis E, Stoger E, Maresch D, Altmann F, Joensuu J, Conrad U: Influence of elastin-like polypeptide and hydrophobin on recombinant hemagglutinin accumulations in transgenic tobacco plants. PLoS One 2014, 9:e99347.
46. Pereira EO, Kolotilin I, Conley AJ, Menassa R: Production and characterization of in planta transiently produced polygalacturanase from Aspergillus niger and its fusions with hydrophobin or ELP tags. BMC Biotechnol 2014, 14:59.
47. Neubauer K, Huhns M, Hausmann T, Klemke F, Lockau W, Kahmann U, Pistorius EK, Kragl U, Broer I: Isolation of cyanophycin from tobacco and potato plants with constitutive plastidic cphATe gene expression. J Biotechnol 2012, 158:50-58.
48. Bohmert-Tatarev K, McAvoy S, Daughtry S, Peoples OP, Snell KD: High levels of bioplastic are produced in fertile transplastomic tobacco plants engineered with a synthetic operon for the production of polyhydroxybutyrate. Plant Physiol 2011, 155:1690-1708.
49. Yuan S, Ort D, Chappell J, Zhu X, Ma H, Kim YK: Rerouting the photorespiration pathway in plants for increasing bioproduct yield US Patent Application 2014/0283219.
50. Somleva M, Chinnapen H, Ali A, Snell KD, Peoples OP, Patterson N, Tang J, Bohmert-Tatarev K: Increasing carbon flow for polyhydroxybutrate production in biomass crops. US Patent Application 2012/0060413.
51. Meng DC, Shen R, Yao H, Chen JC, Wu Q, Chen GQ: Engineering the diversity of polyesters. Curr Opin Biotechnol 2014, 29C:24-33.
52. Slater S, Mitsky TA, Houmiel KL, Hao M, Reiser SE, Taylor NB, Tran M, Valentin HE, Rodriguez DJ, Stone DA, Padgette SR, Kishore G, Gruys KJ: Metabolic engineering of Arabidopsis and Brassica for poly(3-hydroxybutyrate-co-3-hydroxyvalerate) copolymer production. Nat Biotechnol 1999, 17:1011-1016.
53. Yang JE, Choi SY, Shin JH, Park SJ, Lee SY: Microbial production of lactate-containing polyesters. Microb Biotechnol 2013, 6:621-636.
54. Davis J, Moore R, Imperiali B, Pratt A, Kobayashi K, Masamune S, Sinskey A, Walsh C, Fukui T, Tomita K: Biosynthetic thiolase from Zoogloea ramigera. I. Preliminary characterization and analysis of proton transfer reaction. J Biol Chem 1987, 262:82-89.
55. Madison LL, Huisman GW: Metabolic engineering of poly(3-hydroxyalkanoates): from DNA to plastic. Microbiol Mol Biol Rev 1999, 63:21-53.
56. Romer L, Scheibel T: The elaborate structure of spider silk: structure and function of a natural high performance fiber. Prion 2008, 2:154-161.
57. Wise SG, Mithieux SM, Weiss AS: Engineered tropoelastin and elastin-based biomaterials. In Advances in protein chemistry and structural biology. Edited by Alexander M. Academic Press; 2009:1-24.
58. Lee CH, Singla A, Lee Y: Biomedical applications of collagen. Int J Pharm 2001, 221:1-22.
59. Nawrath C, Poirier Y, Somerville C: Targeting of the polyhydroxybutyrate biosynthetic pathway to the plastids of Arabidopsis thaliana results in high levels of polymer accumulation. Proc Natl Acad Sci USA 1994, 91:12760-12764.
60. Nakashita H, Arai Y, Suzuki Y, Yamaguchi I: Molecular breeding of transgenic tobacco plants which accumulate polyhydroxyalkanoates. RIKEN Review 2001, 42:67-70.
61. Nakashita H, Arai Y, Shikanai T, Doi Y, Yamaguchi I: Introduction of bacterial metabolism into higher plants by polycistronic transgene expression. Biosci Biotechnol Biochem 2001, 65:1688-1691.