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Volumn 5, Issue , 2015, Pages

Structural basis for the neutralization of MERS-CoV by a human monoclonal antibody MERS-27

Author keywords

[No Author keywords available]

Indexed keywords

ANTIVIRUS AGENT; MONOCLONAL ANTIBODY; PROTEIN BINDING; VIRUS ENVELOPE PROTEIN;

EID: 84939545662     PISSN: None     EISSN: 20452322     Source Type: Journal    
DOI: 10.1038/srep13133     Document Type: Article
Times cited : (60)

References (39)
  • 2
    • 84878966726 scopus 로고    scopus 로고
    • Middle East Respiratory Syndrome Coronavirus (MERS-CoV); Announcement of the Coronavirus Study Group
    • de Groot, R. J. et al. Middle East Respiratory Syndrome Coronavirus (MERS-CoV); Announcement of the Coronavirus Study Group. J Virol 87, 7790-7792 (2013).
    • (2013) J Virol , vol.87 , pp. 7790-7792
    • De Groot, R.J.1
  • 3
    • 84971623891 scopus 로고    scopus 로고
    • G. State of knowledge and data gaps of middle east respiratory syndrome coronavirus (MERSCoV) in humans
    • The Who Mers-Cov Research, G. State of Knowledge and Data Gaps of Middle East Respiratory Syndrome Coronavirus (MERSCoV) in Humans. PLoS Curr 5, doi: 10.1371/ecurrents.outbreaks.0bf719e352e7478f8ad85fa30127ddb8 (2013).
    • (2013) PLoS Curr , vol.5
    • The Who Mers-Cov Research1
  • 4
    • 84867733836 scopus 로고    scopus 로고
    • Severe respiratory illness caused by a novel coronavirus, in a patient transferred to the United Kingdom from the Middle East, September 2012
    • Bermingham, A. et al. Severe respiratory illness caused by a novel coronavirus, in a patient transferred to the United Kingdom from the Middle East, September 2012. Euro Surveill 17, 20290 (2012).
    • (2012) Euro Surveill , vol.17 , pp. 20290
    • Bermingham, A.1
  • 6
    • 84882598788 scopus 로고    scopus 로고
    • Epidemiological, demographic, and clinical characteristics of 47 cases of Middle East respiratory syndrome coronavirus disease from Saudi Arabia: A descriptive study
    • Assiri, A. et al. Epidemiological, demographic, and clinical characteristics of 47 cases of Middle East respiratory syndrome coronavirus disease from Saudi Arabia: a descriptive study. Lancet Infect Dis 13, 752-761 (2013).
    • (2013) Lancet Infect Dis , vol.13 , pp. 752-761
    • Assiri, A.1
  • 7
    • 84940313968 scopus 로고    scopus 로고
    • Novel coronavirus infections in Jordan, April 2012: Epidemiological findings from a retrospective investigation
    • Hijawi, B. et al. Novel coronavirus infections in Jordan, April 2012: epidemiological findings from a retrospective investigation. East Mediterr Health J 19 Suppl 1, S12-18 (2013).
    • (2013) East Mediterr Health J , vol.19 , pp. S12-18
    • Hijawi, B.1
  • 8
    • 84880088201 scopus 로고    scopus 로고
    • Hospital outbreak of Middle East respiratory syndrome coronavirus
    • Assiri, A. et al. Hospital outbreak of Middle East respiratory syndrome coronavirus. N Engl J Med 369, 407-416 (2013).
    • (2013) N Engl J Med , vol.369 , pp. 407-416
    • Assiri, A.1
  • 9
    • 84880053841 scopus 로고    scopus 로고
    • Clinical features and viral diagnosis of two cases of infection with Middle East Respiratory Syndrome coronavirus: A report of nosocomial transmission
    • Guery, B. et al. Clinical features and viral diagnosis of two cases of infection with Middle East Respiratory Syndrome coronavirus: a report of nosocomial transmission. Lancet 381, 2265-2272 (2013).
    • (2013) Lancet , vol.381 , pp. 2265-2272
    • Guery, B.1
  • 10
    • 84875213690 scopus 로고    scopus 로고
    • Genetic relatedness of the novel human group C betacoronavirus to Tylonycteris bat coronavirus HKU4 and Pipistrellus bat coronavirus HKU5
    • Woo, P. C. Y., Lau, S. K. P., Li, K. S. M., Tsang, A. K. L. & Yuen, K.-Y. Genetic relatedness of the novel human group C betacoronavirus to Tylonycteris bat coronavirus HKU4 and Pipistrellus bat coronavirus HKU5. Emerging Microbes & Infections 1, e35 (2012).
    • (2012) Emerging Microbes & Infections , vol.1 , pp. e35
    • Woo, P.C.Y.1    Lau, S.K.P.2    Li, K.S.M.3    Tsang, A.K.L.4    Yuen, K.-Y.5
  • 11
    • 84871415482 scopus 로고    scopus 로고
    • Genomic characterization of a newly discovered coronavirus associated with acute respiratory distress syndrome in humans
    • van Boheemen, S. et al. Genomic characterization of a newly discovered coronavirus associated with acute respiratory distress syndrome in humans. MBio 3, e00473-12, doi: 10.1128/mbio.00473-12 (2012).
    • (2012) MBio , vol.3
    • Van Boheemen, S.1
  • 12
    • 84880593983 scopus 로고    scopus 로고
    • Genetic characterization of Betacoronavirus lineage C viruses in bats reveals marked sequence divergence in the spike protein of pipistrellus bat coronavirus HKU5 in Japanese pipistrelle: Implications for the origin of the novel Middle East respiratory syndrome coronavirus
    • Lau, S. K. et al. Genetic characterization of Betacoronavirus lineage C viruses in bats reveals marked sequence divergence in the spike protein of pipistrellus bat coronavirus HKU5 in Japanese pipistrelle: implications for the origin of the novel Middle East respiratory syndrome coronavirus. J Virol 87, 8638-8650 (2013).
    • (2013) J Virol , vol.87 , pp. 8638-8650
    • Lau, S.K.1
  • 13
    • 84884233679 scopus 로고    scopus 로고
    • Middle East respiratory syndrome coronavirus in bats, Saudi Arabia
    • Memish, Z. A. et al. Middle East respiratory syndrome coronavirus in bats, Saudi Arabia. Emerg Infect Dis 19, 1819-1823 (2013).
    • (2013) Emerg Infect Dis , vol.19 , pp. 1819-1823
    • Memish, Z.A.1
  • 14
    • 84884228611 scopus 로고    scopus 로고
    • Close relative of human Middle East respiratory syndrome coronavirus in bat, South Africa
    • Ithete, N. L. et al. Close relative of human Middle East respiratory syndrome coronavirus in bat, South Africa. Emerg Infect Dis 19, 1697-1699 (2013).
    • (2013) Emerg Infect Dis , vol.19 , pp. 1697-1699
    • Ithete, N.L.1
  • 15
    • 84884377173 scopus 로고    scopus 로고
    • Middle East respiratory syndrome coronavirus neutralising serum antibodies in dromedary camels: A comparative serological study
    • Reusken, C. B. et al. Middle East respiratory syndrome coronavirus neutralising serum antibodies in dromedary camels: a comparative serological study. Lancet Infect Dis 13, 859-866 (2013).
    • (2013) Lancet Infect Dis , vol.13 , pp. 859-866
    • Reusken, C.B.1
  • 16
    • 84901443765 scopus 로고    scopus 로고
    • MERS coronavirus in dromedary camel herd, Saudi Arabia
    • Hemida, M. G. et al. MERS coronavirus in dromedary camel herd, Saudi Arabia. Emerg Infect Dis 20, 1231-1234 (2014).
    • (2014) Emerg Infect Dis , vol.20 , pp. 1231-1234
    • Hemida, M.G.1
  • 17
    • 84892538696 scopus 로고    scopus 로고
    • Middle East respiratory syndrome coronavirus in dromedary camels: An outbreak investigation
    • Haagmans, B. L. et al. Middle East respiratory syndrome coronavirus in dromedary camels: an outbreak investigation. Lancet Infect Dis 14, 140-145 (2014).
    • (2014) Lancet Infect Dis , vol.14 , pp. 140-145
    • Haagmans, B.L.1
  • 18
    • 10944238037 scopus 로고    scopus 로고
    • Severe acute respiratory syndrome
    • Peiris, J.S.M., Guan, Y. & Yuen, K.Y. Severe acute respiratory syndrome. Nat Med 10, S88-S97 (2004).
    • (2004) Nat Med , vol.10 , pp. S88-S97
    • Peiris, J.S.M.1    Guan, Y.2    Yuen, K.Y.3
  • 19
    • 84890433761 scopus 로고    scopus 로고
    • Middle East respiratory syndrome coronavirus: Quantification of the extent of the epidemic, surveillance biases, and transmissibility
    • Cauchemez, S. et al. Middle East respiratory syndrome coronavirus: quantification of the extent of the epidemic, surveillance biases, and transmissibility. Lancet Infect Dis 14, 50-56 (2014).
    • (2014) Lancet Infect Dis , vol.14 , pp. 50-56
    • Cauchemez, S.1
  • 20
    • 84882918127 scopus 로고    scopus 로고
    • Interhuman transmissibility of Middle East respiratory syndrome coronavirus: Estimation of pandemic risk
    • Breban, R., Riou, J. & Fontanet, A. Interhuman transmissibility of Middle East respiratory syndrome coronavirus: estimation of pandemic risk. Lancet 382, 694-699 (2013).
    • (2013) Lancet , vol.382 , pp. 694-699
    • Breban, R.1    Riou, J.2    Fontanet, A.3
  • 21
    • 33746317830 scopus 로고    scopus 로고
    • The molecular biology of coronaviruses
    • Masters, P. S. The molecular biology of coronaviruses. Adv Virus Res 66, 193-292 (2006).
    • (2006) Adv Virus Res , vol.66 , pp. 193-292
    • Masters, P.S.1
  • 22
    • 84874996988 scopus 로고    scopus 로고
    • Dipeptidyl peptidase 4 is a functional receptor for the emerging human coronavirus-EMC
    • Raj, V. S. et al. Dipeptidyl peptidase 4 is a functional receptor for the emerging human coronavirus-EMC. Nature 495, 251-254 (2013).
    • (2013) Nature , vol.495 , pp. 251-254
    • Raj, V.S.1
  • 23
    • 84875610424 scopus 로고    scopus 로고
    • A predicted receptor-binding and critical neutralizing domain in s protein of the novel human coronavirus HCoV-EMC
    • Jiang, S., Lu, L., Du, L. & Debnath, A. K. A predicted receptor-binding and critical neutralizing domain in S protein of the novel human coronavirus HCoV-EMC. J Infect 66, 464-466 (2013).
    • (2013) J Infect , vol.66 , pp. 464-466
    • Jiang, S.1    Lu, L.2    Du, L.3    Debnath, A.K.4
  • 24
    • 84881232247 scopus 로고    scopus 로고
    • The receptor binding domain of the new Middle East respiratory syndrome coronavirus maps to a 231-residue region in the spike protein that efficiently elicits neutralizing antibodies
    • Mou, H. et al. The receptor binding domain of the new Middle East respiratory syndrome coronavirus maps to a 231-residue region in the spike protein that efficiently elicits neutralizing antibodies. J Virol 87, 9379-9383 (2013).
    • (2013) J Virol , vol.87 , pp. 9379-9383
    • Mou, H.1
  • 25
    • 84881190964 scopus 로고    scopus 로고
    • Structure of MERS-CoV spike receptor-binding domain complexed with human receptor DPP4
    • Wang, N. et al. Structure of MERS-CoV spike receptor-binding domain complexed with human receptor DPP4. Cell Res 23, 986-993 (2013).
    • (2013) Cell Res , vol.23 , pp. 986-993
    • Wang, N.1
  • 26
    • 84881479703 scopus 로고    scopus 로고
    • Molecular basis of binding between novel human coronavirus MERS-CoV and its receptor CD26
    • Lu, G. et al. Molecular basis of binding between novel human coronavirus MERS-CoV and its receptor CD26. Nature 500, 227-231 (2013).
    • (2013) Nature , vol.500 , pp. 227-231
    • Lu, G.1
  • 27
    • 84899797757 scopus 로고    scopus 로고
    • Potent neutralization of MERS-CoV by human neutralizing monoclonal antibodies to the viral spike glycoprotein
    • Jiang, L. et al. Potent neutralization of MERS-CoV by human neutralizing monoclonal antibodies to the viral spike glycoprotein. Sci Transl Med 6, 234ra259, doi: 10.1126/scitranslmed.3008140 (2014).
    • (2014) Sci Transl Med , vol.6 , pp. 234ra259
    • Jiang, L.1
  • 28
    • 84900515662 scopus 로고    scopus 로고
    • Identification of human neutralizing antibodies against MERS-CoV and their role in virus adaptive evolution
    • Tang, X. C. et al. Identification of human neutralizing antibodies against MERS-CoV and their role in virus adaptive evolution. Proc Natl Acad Sci USA 111, E2018-2026 (2014).
    • (2014) Proc Natl Acad Sci USA , vol.111 , pp. E2018-2026
    • Tang, X.C.1
  • 29
    • 84904663317 scopus 로고    scopus 로고
    • Exceptionally potent neutralization of Middle East respiratory syndrome coronavirus by human monoclonal antibodies
    • Ying, T. et al. Exceptionally potent neutralization of Middle East respiratory syndrome coronavirus by human monoclonal antibodies. J Virol 88, 7796-7805 (2014).
    • (2014) J Virol , vol.88 , pp. 7796-7805
    • Ying, T.1
  • 30
    • 84901303550 scopus 로고    scopus 로고
    • A conformation-dependent neutralizing monoclonal antibody specifically targeting receptor-binding domain in Middle East respiratory syndrome coronavirus spike protein
    • Du, L. et al. A conformation-dependent neutralizing monoclonal antibody specifically targeting receptor-binding domain in Middle East respiratory syndrome coronavirus spike protein. J Virol 88, 7045-7053 (2014).
    • (2014) J Virol , vol.88 , pp. 7045-7053
    • Du, L.1
  • 31
    • 84886007720 scopus 로고    scopus 로고
    • Crystal structure of the receptor-binding domain from newly emerged Middle East respiratory syndrome coronavirus
    • Chen, Y. et al. Crystal structure of the receptor-binding domain from newly emerged Middle East respiratory syndrome coronavirus. J Virol 87, 10777-10783 (2013).
    • (2013) J Virol , vol.87 , pp. 10777-10783
    • Chen, Y.1
  • 32
    • 84906658079 scopus 로고    scopus 로고
    • Receptor usage and cell entry of bat coronavirus HKU4 provide insight into bat-to-human transmission of MERS coronavirus
    • Yang, Y. et al. Receptor usage and cell entry of bat coronavirus HKU4 provide insight into bat-to-human transmission of MERS coronavirus. Proc Natl Acad Sci USA 111, 12516-12521 (2014).
    • (2014) Proc Natl Acad Sci USA , vol.111 , pp. 12516-12521
    • Yang, Y.1
  • 33
    • 84907681989 scopus 로고    scopus 로고
    • Bat origins of MERS-CoV supported by bat coronavirus HKU4 usage of human receptor CD26
    • Wang, Q. et al. Bat Origins of MERS-CoV Supported by Bat Coronavirus HKU4 Usage of Human Receptor CD26. Cell Host Microbe 16, 328-337 (2014).
    • (2014) Cell Host Microbe , vol.16 , pp. 328-337
    • Wang, Q.1
  • 34
    • 0031059866 scopus 로고    scopus 로고
    • Processing of X-ray diffraction data collected in oscillation mode Method
    • Otwinowski, Z. Minor, W. Processing of X-ray diffraction data collected in oscillation mode Method. Enzymol. 276, 307-326 (1997).
    • (1997) Enzymol. , vol.276 , pp. 307-326
    • Otwinowski, Z.1    Minor, W.2
  • 35
    • 34447508216 scopus 로고    scopus 로고
    • Phaser crystallographic software
    • McCoy, A. J. et al. Phaser crystallographic software. J. Appl. Crystallogr. 40, 658-674 (2007).
    • (2007) J. Appl. Crystallogr. , vol.40 , pp. 658-674
    • McCoy, A.J.1
  • 36
    • 14244272868 scopus 로고    scopus 로고
    • PHENIX: Building new software for automated crystallographic structure determination
    • Adams, P. D. et al. PHENIX: building new software for automated crystallographic structure determination. Acta Crystallogr. D 58, 1948-1954 (2002).
    • (2002) Acta Crystallogr. D , vol.58 , pp. 1948-1954
    • Adams, P.D.1
  • 37
    • 13244281317 scopus 로고    scopus 로고
    • Coot: Model-building tools for molecular graphics
    • Emsley, P. & Cowtan, K. Coot: model-building tools for molecular graphics. Acta Crystallogr. D 60, 2126-2132 (2004).
    • (2004) Acta Crystallogr. D , vol.60 , pp. 2126-2132
    • Emsley, P.1    Cowtan, K.2
  • 38
    • 0000243829 scopus 로고
    • PROCHECK: A program to check the stereochemical quality of protein structures
    • Laskowski, R. A., MacArthur, M. W., Moss, D. S. & Thornton, J. M. PROCHECK: a program to check the stereochemical quality of protein structures. J. Appl. Crystallogr. 26, 283-291 (1993).
    • (1993) J. Appl. Crystallogr. , vol.26 , pp. 283-291
    • Laskowski, R.A.1    MacArthur, M.W.2    Moss, D.S.3    Thornton, J.M.4


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