Molecular characterization of extended-spectrum beta-lactamases (ESBLs) produced by clinical isolates of Acinetobacter baumannii in Saudi Arabia

Annals of Clinical Microbiology and Antimicrobials

Volumn 14, Issue 1, 2015, Pages

  Alyamani, Essam J ^a   Khiyami, Mohamed A ^a   Booq, Rayan Y ^a   Alnafjan, Basel M ^a   Altammami, Musaad A ^a   Bahwerth, Fayez S ^b  

^a KING ABDULAZIZ CITY FOR SCIENCE AND TECHNOLOGY   (Saudi Arabia)

^b Herra General Hospital   (Saudi Arabia)

Author keywords

Acinetobacter baumannii; Genotyping; Phenotyping; Saudi Arabia

Indexed keywords

AZTREONAM; BACTERIAL ENZYME; BETA LACTAMASE CTX M; BETA LACTAMASE CTX M 1; BETA LACTAMASE CTX M 2; BETA LACTAMASE CTX M 25; BETA LACTAMASE CTX M 8; BETA LACTAMASE CTX M 9; CARBAPENEM; CEFEPIME; CEFTAZIDIME; EXTENDED SPECTRUM BETA LACTAMASE; OXA 23 LIKE ENZYME; OXA 51 LIKE ENZYME; TEM ENZYME; UNCLASSIFIED DRUG; BETA LACTAMASE;

ACINETOBACTER BAUMANNII; ANTIBIOTIC SENSITIVITY; ARTICLE; BACTERIAL STRAIN; BACTERIUM ISOLATE; CONTROLLED STUDY; GENE IDENTIFICATION; GENETIC VARIABILITY; GENOTYPE; INTENSIVE CARE UNIT; MULTILOCUS SEQUENCE TYPING; NONHUMAN; PHENOTYPE; POLYMERASE CHAIN REACTION; PREVALENCE; SAUDI ARABIA; ACINETOBACTER INFECTIONS; DNA SEQUENCE; DRUG EFFECTS; ENZYMOLOGY; GENETIC VARIATION; GENETICS; HOSPITAL; HUMAN; ISOLATION AND PURIFICATION; MICROBIAL SENSITIVITY TEST; MICROBIOLOGY; SECRETION (PROCESS);

ACINETOBACTER BAUMANNII; ACINETOBACTER INFECTIONS; BETA-LACTAMASES; GENETIC VARIATION; HOSPITALS; HUMANS; INTENSIVE CARE UNITS; MICROBIAL SENSITIVITY TESTS; MULTILOCUS SEQUENCE TYPING; PREVALENCE; SAUDI ARABIA; SEQUENCE ANALYSIS, DNA;

EID: 84939536212     PISSN: None     EISSN: 14760711     Source Type: Journal    
DOI: 10.1186/s12941-015-0098-9     Document Type: Article

References (42)

1. Eliopoulos GM, Maragakis LL, Perl TM (2008) Acinetobacter baumannii: epidemiology, antimicrobial resistance, and treatment options. Clin Infect Dis 46(8):1254-1263
2. Antunes L, Visca P, Towner KJ (2014) Acinetobacter baumannii: evolution of a global pathogen. Pathog Dis 71(3):292-301
3. Srinivasan VB, Rajamohan G, Pancholi P, Stevenson K, Tadesse D, Patchanee P, Marcon M, Gebreyes WA (2009) Genetic relatedness and molecular characterization of multidrug resistant Acinetobacter baumannii isolated in central Ohio, USA. Ann Clin Microbiol Antimicrob 8(1):21
4. Bergogne-Berezin E, Towner KJ (1996) Acinetobacter spp. as nosocomial pathogens: microbiological, clinical, and epidemiological features. Clin Microbiol Rev 9(2):148-165
5. Peleg AY, Seifert H, Paterson DL (2008) Acinetobacter baumannii: emergence of a successful pathogen. Clin Microbiol Rev 21(3):538-582
6. Perez F, Hujer AM, Hujer KM, Decker BK, Rather PN, Bonomo RA (2007) Global challenge of multidrug-resistant Acinetobacter baumannii. Antimicrob Agents Chemother 51(10):3471-3484
7. Knothe H, Shah PDP, Krcmery V, Antal M, Mitsuhashi S (1983) Transferable resistance to cefotaxime, cefoxitin, cefamandole and cefuroxime in clinical isolates of Klebsiella pneumoniae and Serratia marcescens. Infection 11(6):315-317
8. Philippon A, Labia R, Jacoby G (1989) Extended-spectrum beta-lactamases. Antimicrob Agents Chemother 33(8):1131
9. Rawat D, Nair D (2010) Extended-spectrum β-lactamases in Gram negative bacteria. J Glob Infect Dis 2(3):263
10. Fluit AC, Visser MR, Schmitz FJ (2001) Molecular detection of antimicrobial resistance. Clin Microb Rev 14(4):836-871
11. Bush K, Jacoby GA (2010) Updated functional classification of β-lactamases. Antimicrob Agents Chemother 54(3):969-976
12. Paterson DL, Bonomo RA (2005) Extended-spectrum β-lactamases: a clinical update. Clin Microbiol Rev 18(4):657-686
13. Naas T, Oxacelay C, Nordmann P (2007) Identification of CTX-M-type extended-spectrum-β-lactamase genes using real-tme PCR and pyrosequencing. Antimicrob Agents Chemother 51(1):223-230
14. Naas T, Cuzon G, Bogaerts P, Glupczynski Y, Nordmann P (2011) Evaluation of a DNA microarray (Check-MDR CT102) for rapid detection of TEM, SHV, and CTX-M extended-spectrum beta-lactamases and of KPC, OXA-48, VIM, IMP, and NDM-1 carbapenemases. J Clin Microbiol 49(4):1608-1613
15. Al Johani SM, Akhter J, Balkhy H, El-Saed A, Younan M, Memish Z (2010) Prevalence of antimicrobial resistance among gram-negative isolates in an adult intensive care unit at a tertiary care center in Saudi Arabia. Ann Saudi Med 30(5):364
16. Al-Agamy MH, Shibl AM, Ali MS, Khubnani H, Radwan HH, Livermore DM (2014) Distribution of β-lactamases in carbapenem-non-susceptible Acinetobacter baumannii in Riyadh, Saudi Arabia. J Glob Antimicrob Resist 2(1):17-21
17. Zowawi HM, Sartor AL, Sidjabat HE, Balkhy HH, Walsh TR, Al Johani SM, AlJindan RY, Alfaresi M, Ibrahim E, Al-Jardani A et al (2015) Molecular epidemiology of carbapenem resistant Acinetobacter baumannii in the Gulf Cooperation Council States. Dominance of OXA-23-type producers. J Clin Microb 53:896-903
18. Dallenne C, Da Costa A, Decre D, Favier C, Arlet G (2010) Development of a set of multiplex PCR assays for the detection of genes encoding important beta-lactamases in Enterobacteriaceae. J Antimicrob Chemother 65(3):490-495
19. Bartual SG, Seifert H, Hippler C, Luzon MA, Wisplinghoff H, Rodriguez-Valera F (2005) Development of a multilocus sequence typing scheme for characterization of clinical isolates of Acinetobacter baumannii. J Clin Microbiol 43(9):4382-4390
20. Bosshard PP, Abels S, Altwegg M, Böttger EC, Zbinden R (2004) Comparison of conventional and molecular methods for identification of aerobic catalase-negative gram-positive cocci in the clinical laboratory. J Clin Microbiol 42(5):2065-2073
21. Maidak BL, Olsen GJ, Larsen N, Overbeek R, McCaughey MJ, Woese CR (1996) The Ribosomal database project (RDP). Nucleic Acids Res 24(1):82-85
22. Lee MJ, Jang SJ, Li XM, Park G, Kook J-K, Kim MJ, Chang Y-H, Shin JH, Kim SH, Kim D-M et al (2014) Comparison of rpoB gene sequencing, 16S rRNA gene sequencing, gyrB multiplex PCR, and the VITEK2 system for identification of Acinetobacter clinical isolates. Diagn Microbiol Infect Dis 78(1):29-34
23. Jolley K, Maiden M (2010) BIGSdb: scalable analysis of bacterial genome variation at the population level. BMC Bioinform 11(1):595
24. Larsen N, Olsen GJ, Maidak BL, McCaughey MJ, Overbeek R, Macke TJ, Marsh TL, Woese CR (1993) The ribosomal database project. Nucleic Acids Res 21(13):3021-3023
25. Lahlaoui H, Ben Haj Khalifa A, Ben Moussa M (2014) Epidemiology of Enterobacteriaceae producing CTX-M type extended spectrum beta-lactamase (ESBL). Med Mal Infect 44(9):400-404
26. Canton R, Novais A, Valverde A, Machado E, Peixe L, Baquero F, Coque TM (2008) Prevalence and spread of extended-spectrum beta-lactamase-producing Enterobacteriaceae in Europe. Clin Microbiol Infect 14(Suppl 1):144-153
27. Huber CA, Sartor AL, McOdimba F, Shah R, Shivachi P, Sidjabat HE, Revathi G, Paterson DL (2014) Outbreaks of multidrug-resistant Acinetobacter baumannii strains in a Kenyan teaching hospital. J Glob Antimicrob Resist 2(3):190-193
28. Jeannot K, Diancourt L, Vaux S, Thouverez M, Ribeiro A, Coignard B, Courvalin P, Brisse S (2014) Molecular epidemiology of carbapenem non-susceptible Acinetobacter baumannii in France. PLoS One 9(12):e115452
29. Pournaras S, Gogou V, Giannouli M, Dimitroulia E, Dafopoulou K, Tsakris A, Zarrilli R (2014) Single-locus-sequence-based typing of blaOXA-51-like genes for rapid assignment of acinetobacter baumannii clinical isolates to international clonal lineages. J Clin Microbiol 52(5):1653-1657
30. Evans BA, Hamouda A, Amyes SG (2013) The rise of carbapenem-resistant Acinetobacter baumannii. Curr Pharm Des 19(2):223-238
31. Paton R, Miles RS, Hood J, Amyes SG, Miles RS, Amyes SG (1993) ARI 1: beta-lactamase-mediated imipenem resistance in Acinetobacter baumannii. Int J Antimicrob Agents 2(2):81-87
32. Brown S, Young HK, Amyes SG (2005) Characterisation of OXA-51, a novel class D carbapenemase found in genetically unrelated clinical strains of Acinetobacter baumannii from Argentina. Clin Microbiol Infect Off Publ Eur Soc Clin Microbiol Infect Dis 11(1):15-23
33. Coelho JM, Turton JF, Kaufmann ME, Glover J, Woodford N, Warner M, Palepou M-F, Pike R, Pitt TL, Patel BC (2006) Occurrence of carbapenem-resistant Acinetobacter baumannii clones at multiple hospitals in London and Southeast England. J Clin Microbiol 44(10):3623-3627
34. Walther-Rasmussen J, Høiby N (2006) OXA-type carbapenemases. J Antimicrob Chemother 57(3):373-383
35. Turton JF, Ward ME, Woodford N, Kaufmann ME, Pike R, Livermore DM, Pitt TL (2006) The role of ISAba1 in expression of OXA carbapenemase genes in Acinetobacter baumannii. FEMS Microbiol Lett 258(1):72-77
36. Karah N, Sundsfjord A, Towner K, Samuelsen O (2012) Insights into the global molecular epidemiology of carbapenem non-susceptible clones of Acinetobacter baumannii. Drug Resist Updates Rev Comment Antimicrob Anticancer Chemother 15(4):237-247
37. Zowawi HM, Sartor AL, Balkhy HH, Walsh TR, Al Johani SM, AlJindan RY, Alfaresi M, Ibrahim E, Al-Jardani A, Al-Abri S et al (2014) Molecular characterization of carbapenemase-producing Escherichia coli and Klebsiella pneumoniae in the countries of the Gulf cooperation council: dominance of OXA-48 and NDM producers. Antimicrob Agents Chemother 58(6):3085-3090
38. Memish ZA, Assiri A, Almasri M, Roshdy H, Hathout H, Kaase M, Gatermann SG, Yezli S (2015) Molecular characterization of carbapenemase production among gram-negative bacteria in Saudi Arabia. Microb Drug Resist 21(3):307-314
39. Memish ZA (2002) Infection control in Saudi Arabia: meeting the challenge. Am J Infect Control 30(1):57-65
40. Aly M, Tayeb HT, Al Johani SM, Alyamani EJ, Aldughaishem F, Alabdulkarim I, Balkhy HH (2014) Genetic diversity of OXA-51-like genes among multidrug-resistant Acinetobacter baumannii in Riyadh, Saudi Arabia. Eur J Clin Microbiol Infect Dis Off Publ Eur Soc Clin Microbiol 33(7):1223-1228
41. Dijkshoorn L, Nemec A, Seifert H (2007) An increasing threat in hospitals: multidrug-resistant Acinetobacter baumannii. Nat Rev Microbiol 5(12):939-951
42. Diancourt L, Passet V, Nemec A, Dijkshoorn L, Brisse S (2010) The population structure of Acinetobacter baumannii: expanding multiresistant clones from an ancestral susceptible genetic pool. PLoS One 5(4):e10034