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Volumn 240, Issue 8, 2015, Pages 1087-1098

From humble beginnings to success in the clinic: Chimeric antigen receptor-modified T-cells and implications for immunotherapy

Author keywords

Cancer; immunology molecular; lymphocyte; medicine oncology; therapy; tumor

Indexed keywords

CANCER TESTIS ANTIGEN; CARCINOEMBRYONIC ANTIGEN; CD19 ANTIGEN; CHIMERIC ANTIGEN RECEPTOR; GAMMA INTERFERON; INTERLEUKIN 1; INTERLEUKIN 12; INTERLEUKIN 15; INTERLEUKIN 17; INTERLEUKIN 2; INTERLEUKIN 7; MELAN A; MELANOMA ANTIGEN 3; PROGRAMMED DEATH 1 RECEPTOR; T LYMPHOCYTE RECEPTOR; TUMOR ANTIGEN; TUMOR NECROSIS FACTOR ALPHA; HYBRID PROTEIN; LYMPHOCYTE ANTIGEN RECEPTOR;

EID: 84939529597     PISSN: 15353702     EISSN: 15353699     Source Type: Journal    
DOI: 10.1177/1535370215584936     Document Type: Article
Times cited : (54)

References (64)
  • 1
    • 0025821777 scopus 로고
    • Graft-versus-host disease in experimental allogeneic bone marrow transplantation
    • R.KorngoldJ.Sprent. Graft-versus-host disease in experimental allogeneic bone marrow transplantation. Proc Soc Exp Biol Med Soc Exp Biol Med1991; 197: 12–8.
    • (1991) Proc Soc Exp Biol Med Soc Exp Biol Med , vol.197 , pp. 12-18
    • Korngold, R.1    Sprent, J.2
  • 3
    • 84939511107 scopus 로고    scopus 로고
    • Lyon: WHO Press, 2014. xiv
    • Stewart BW, Wild C. International Agency for Research on Cancer, World Health Organization. World cancer report 2014. Lyon: WHO Press, 2014. xiv, 630 p
    • (2014) 630 p
  • 4
    • 0001739064 scopus 로고
    • Intradermal immunization of C3H mice against a sarcoma that originated in an animal of the same line
    • L.Gross. Intradermal immunization of C3H mice against a sarcoma that originated in an animal of the same line. Cancer Res1943; 3: 326–33.
    • (1943) Cancer Res , vol.3 , pp. 326-333
    • Gross, L.1
  • 5
    • 84965157146 scopus 로고
    • Antigenic properties of methylcholanthrene-induced tumors in mice of the strain of origin
    • E.J.Foley. Antigenic properties of methylcholanthrene-induced tumors in mice of the strain of origin. Cancer Res1953; 13: 835–7.
    • (1953) Cancer Res , vol.13 , pp. 835-837
    • Foley, E.J.1
  • 6
    • 33847190697 scopus 로고    scopus 로고
    • The toxins of William B. Coley and the treatment of bone and soft-tissue sarcomas
    • E.F.McCarthy. The toxins of William B. Coley and the treatment of bone and soft-tissue sarcomas. Iowa Orthopaed J2006; 26: 154–8.
    • (2006) Iowa Orthopaed J , vol.26 , pp. 154-158
    • McCarthy, E.F.1
  • 7
    • 84902314288 scopus 로고    scopus 로고
    • Clinical application of adoptive T cell therapy in solid tumors
    • Y.-W.ZangX.-D.GuJ.-B.XiangZ.-Y.Chen. Clinical application of adoptive T cell therapy in solid tumors. Med Sci Monit2014; 20: 953–9.
    • (2014) Med Sci Monit , vol.20 , pp. 953-959
    • Zang, Y.-W.1    Gu, X.-D.2    Xiang, J.-B.3    Chen, Z.-Y.4
  • 10
    • 77649184739 scopus 로고    scopus 로고
    • The regulation of IL-10 production by immune cells
    • M.SaraivaA.O'Garra. The regulation of IL-10 production by immune cells. Nat Rev Immunol2010; 10: 170–81.
    • (2010) Nat Rev Immunol , vol.10 , pp. 170-181
    • Saraiva, M.1    O'Garra, A.2
  • 11
    • 84858766182 scopus 로고    scopus 로고
    • The blockade of immune checkpoints in cancer immunotherapy
    • D.M.Pardoll. The blockade of immune checkpoints in cancer immunotherapy. Nat Rev Cancer2012; 12: 252–64.
    • (2012) Nat Rev Cancer , vol.12 , pp. 252-264
    • Pardoll, D.M.1
  • 12
    • 78449243489 scopus 로고    scopus 로고
    • Immune checkpoint proteins: a new therapeutic paradigm for cancer–preclinical background: CTLA-4 and PD-1 blockade
    • J.Weber. Immune checkpoint proteins: a new therapeutic paradigm for cancer–preclinical background: CTLA-4 and PD-1 blockade. Semin Oncol2010; 37: 430–9.
    • (2010) Semin Oncol , vol.37 , pp. 430-439
    • Weber, J.1
  • 14
    • 84858766182 scopus 로고    scopus 로고
    • The blockade of immune checkpoints in cancer immunotherapy
    • D.M.Pardoll. The blockade of immune checkpoints in cancer immunotherapy. Nat Rev Cancer2012; 12: 252–64.
    • (2012) Nat Rev Cancer , vol.12 , pp. 252-264
    • Pardoll, D.M.1
  • 15
    • 84904855312 scopus 로고    scopus 로고
    • Immunologic and clinical effects of targeting PD-1 in lung cancer
    • R.D.Harvey. Immunologic and clinical effects of targeting PD-1 in lung cancer. Clin Pharmacol Ther2014; 96: 214–23.
    • (2014) Clin Pharmacol Ther , vol.96 , pp. 214-223
    • Harvey, R.D.1
  • 18
    • 13844294372 scopus 로고    scopus 로고
    • PD-1 blockade inhibits hematogenous spread of poorly immunogenic tumor cells by enhanced recruitment of effector T cells
    • Y.IwaiS.TerawakiT.Honjo. PD-1 blockade inhibits hematogenous spread of poorly immunogenic tumor cells by enhanced recruitment of effector T cells. Int Immunol2005; 17: 133–44.
    • (2005) Int Immunol , vol.17 , pp. 133-144
    • Iwai, Y.1    Terawaki, S.2    Honjo, T.3
  • 24
    • 78049370405 scopus 로고    scopus 로고
    • Integrative analysis reveals selective 9p24.1 amplification, increased PD-1 ligand expression, and further induction via JAK2 in nodular sclerosing Hodgkin lymphoma and primary mediastinal large B-cell lymphoma
    • M.R.GreenS.MontiS.J.RodigP.JuszczynskiT.CurrieE.O'DonnellB.ChapuyK.TakeyamaD.NeubergT.R.GolubJ.L.KutokM.A.Shipp. Integrative analysis reveals selective 9p24.1 amplification, increased PD-1 ligand expression, and further induction via JAK2 in nodular sclerosing Hodgkin lymphoma and primary mediastinal large B-cell lymphoma. Blood2010; 116: 3268–77.
    • (2010) Blood , vol.116 , pp. 3268-3277
    • Green, M.R.1    Monti, S.2    Rodig, S.J.3    Juszczynski, P.4    Currie, T.5    O'Donnell, E.6    Chapuy, B.7    Takeyama, K.8    Neuberg, D.9    Golub, T.R.10    Kutok, J.L.11    Shipp, M.A.12
  • 26
    • 75449110618 scopus 로고    scopus 로고
    • Tissue-specific differences in PD-1 and PD-L1 expression during chronic viral infection: implications for CD8 T-cell exhaustion
    • S.D.BlackburnA.CrawfordH.ShinA.PolleyG.J.FreemanE.J.Wherry. Tissue-specific differences in PD-1 and PD-L1 expression during chronic viral infection: implications for CD8 T-cell exhaustion. J Virol2010; 84: 2078–89.
    • (2010) J Virol , vol.84 , pp. 2078-2089
    • Blackburn, S.D.1    Crawford, A.2    Shin, H.3    Polley, A.4    Freeman, G.J.5    Wherry, E.J.6
  • 27
    • 54449088740 scopus 로고    scopus 로고
    • Selective expansion of a subset of exhausted CD8 T cells by alphaPD-L1 blockade
    • S.D.BlackburnH.ShinG.J.FreemanE.J.Wherry. Selective expansion of a subset of exhausted CD8 T cells by alphaPD-L1 blockade. Proc Natl Acad Sci U S A2008; 105: 15016–21.
    • (2008) Proc Natl Acad Sci U S A , vol.105 , pp. 15016-15021
    • Blackburn, S.D.1    Shin, H.2    Freeman, G.J.3    Wherry, E.J.4
  • 33
    • 65249173447 scopus 로고    scopus 로고
    • Adoptive cell therapy for the treatment of patients with metastatic melanoma
    • S.A.RosenbergM.E.Dudley. Adoptive cell therapy for the treatment of patients with metastatic melanoma. Curr Opin Immunol2009; 21: 233–40.
    • (2009) Curr Opin Immunol , vol.21 , pp. 233-240
    • Rosenberg, S.A.1    Dudley, M.E.2
  • 35
    • 0037829421 scopus 로고    scopus 로고
    • Generation of tumor-infiltrating lymphocyte cultures for use in adoptive transfer therapy for melanoma patients
    • M.E.DudleyJ.R.WunderlichT.E.SheltonJ.EvenS.A.Rosenberg. Generation of tumor-infiltrating lymphocyte cultures for use in adoptive transfer therapy for melanoma patients. J Immunother2003; 26: 332–42.
    • (2003) J Immunother , vol.26 , pp. 332-342
    • Dudley, M.E.1    Wunderlich, J.R.2    Shelton, T.E.3    Even, J.4    Rosenberg, S.A.5
  • 36
    • 79958845363 scopus 로고    scopus 로고
    • Tumor-infiltrating immune cells and prognosis: the potential link between conventional cancer therapy and immunity
    • C.JochemsJ.Schlom. Tumor-infiltrating immune cells and prognosis: the potential link between conventional cancer therapy and immunity. Exp Biol Med2011; 236: 567–79.
    • (2011) Exp Biol Med , vol.236 , pp. 567-579
    • Jochems, C.1    Schlom, J.2
  • 41
    • 22144436297 scopus 로고    scopus 로고
    • Mouse models expressing human carcinoembryonic antigen (CEA) as a transgene: evaluation of CEA-based cancer vaccines
    • K.W.HanceH.E.ZeytinJ.W.Greiner. Mouse models expressing human carcinoembryonic antigen (CEA) as a transgene: evaluation of CEA-based cancer vaccines. Mutat Res Fundam Mol Mech Mutagen2005; 576: 132–54.
    • (2005) Mutat Res Fundam Mol Mech Mutagen , vol.576 , pp. 132-154
    • Hance, K.W.1    Zeytin, H.E.2    Greiner, J.W.3
  • 42
    • 0036554096 scopus 로고    scopus 로고
    • The potential of DNA vaccination against tumor-associated antigens for antitumor therapy
    • K.HauptM.RoggendorfK.Mann. The potential of DNA vaccination against tumor-associated antigens for antitumor therapy. Exp Biol Med2002; 227: 227–37.
    • (2002) Exp Biol Med , vol.227 , pp. 227-237
    • Haupt, K.1    Roggendorf, M.2    Mann, K.3
  • 45
    • 82455175361 scopus 로고    scopus 로고
    • MAGE-A family: attractive targets for cancer immunotherapy
    • M.SangY.LianX.ZhouB.Shan. MAGE-A family: attractive targets for cancer immunotherapy. Vaccine2011; 29: 8496–500.
    • (2011) Vaccine , vol.29 , pp. 8496-8500
    • Sang, M.1    Lian, Y.2    Zhou, X.3    Shan, B.4
  • 50
    • 80051775476 scopus 로고    scopus 로고
    • T cells with chimeric antigen receptors have potent antitumor effects and can establish memory in patients with advanced leukemia
    • Kalos M, Levine BL, Porter DL, Katz S, Grupp SA, Bagg A, June CH. T cells with chimeric antigen receptors have potent antitumor effects and can establish memory in patients with advanced leukemia. Sci Transl Med 2011;3
    • (2011) Sci Transl Med , pp. 3
    • Kalos, M.1    Levine, B.2    Porter, D.3    Katz, S.4    Grupp, S.5    Bagg, A.6    June, C.7
  • 51
    • 80051720194 scopus 로고    scopus 로고
    • Chimeric antigen receptor-modified T cells in chronic lymphoid leukemia
    • D.L.PorterB.L.LevineM.KalosA.BaggC.H.June. Chimeric antigen receptor-modified T cells in chronic lymphoid leukemia. N Engl J Med2011; 365: 725–33.
    • (2011) N Engl J Med , vol.365 , pp. 725-733
    • Porter, D.L.1    Levine, B.L.2    Kalos, M.3    Bagg, A.4    June, C.H.5
  • 53
    • 33646440024 scopus 로고    scopus 로고
    • Treatment of metastatic renal cell carcinoma with autologous T-lymphocytes genetically retargeted against carbonic anhydrase IX: first clinical experience
    • C.H.J.LamersS.SleijferA.G.VultoW.H.J.KruitM.KliffenR.DebetsJ.W.GratamaG.StoterE.Oosterwijk. Treatment of metastatic renal cell carcinoma with autologous T-lymphocytes genetically retargeted against carbonic anhydrase IX: first clinical experience. J Clin Oncol2006; 24: e20–2.
    • (2006) J Clin Oncol , vol.24 , pp. 20-22
    • Lamers, C.H.J.1    Sleijfer, S.2    Vulto, A.G.3    Kruit, W.H.J.4    Kliffen, M.5    Debets, R.6    Gratama, J.W.7    Stoter, G.8    Oosterwijk, E.9
  • 55
    • 77950475517 scopus 로고    scopus 로고
    • Case report of a serious adverse event following the administration of T cells transduced with a chimeric antigen receptor recognizing ERBB2
    • R.A.MorganJ.C.YangM.KitanoM.E.DudleyC.M.LaurencotS.A.Rosenberg. Case report of a serious adverse event following the administration of T cells transduced with a chimeric antigen receptor recognizing ERBB2. Mol Ther2010; 18: 843–51.
    • (2010) Mol Ther , vol.18 , pp. 843-851
    • Morgan, R.A.1    Yang, J.C.2    Kitano, M.3    Dudley, M.E.4    Laurencot, C.M.5    Rosenberg, S.A.6
  • 60
    • 34548858453 scopus 로고    scopus 로고
    • Phase I study of SS1P a recombinant anti-mesothelin immunotoxin given as a bolus IV infusion to patients with mesothelin-expressing mesothelioma, ovarian, and pancreatic cancers
    • R.HassanS.BullockA.PremkumarR.J.KreitmanH.KindlerM.C.WillinghamI.Pastan. Phase I study of SS1P a recombinant anti-mesothelin immunotoxin given as a bolus IV infusion to patients with mesothelin-expressing mesothelioma, ovarian, and pancreatic cancers. Clin Cancer Res2007; 13: 5144–9.
    • (2007) Clin Cancer Res , vol.13 , pp. 5144-5149
    • Hassan, R.1    Bullock, S.2    Premkumar, A.3    Kreitman, R.J.4    Kindler, H.5    Willingham, M.C.6    Pastan, I.7
  • 61
    • 67349189462 scopus 로고    scopus 로고
    • Adoptive immunotherapy using human peripheral blood lymphocytes transferred with RNA encoding Her-2/neu-specific chimeric immune receptor in ovarian cancer xenograft model
    • S.H.YoonJ.M.LeeH.I.ChoE.K.KimH.S.KimM.Y.ParkT.G.Kim. Adoptive immunotherapy using human peripheral blood lymphocytes transferred with RNA encoding Her-2/neu-specific chimeric immune receptor in ovarian cancer xenograft model. Cancer Gene Ther2009; 16: 489–97.
    • (2009) Cancer Gene Ther , vol.16 , pp. 489-497
    • Yoon, S.H.1    Lee, J.M.2    Cho, H.I.3    Kim, E.K.4    Kim, H.S.5    Park, M.Y.6    Kim, T.G.7
  • 63
    • 1342289322 scopus 로고    scopus 로고
    • Activation of the T-cell oncogene LMO2 after gene therapy for X-linked severe combined immunodeficiency
    • M.P.McCormackT.H.Rabbitts. Activation of the T-cell oncogene LMO2 after gene therapy for X-linked severe combined immunodeficiency. N Engl J Med2004; 350: 913–22.
    • (2004) N Engl J Med , vol.350 , pp. 913-922
    • McCormack, M.P.1    Rabbitts, T.H.2


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