Pancreatic iron overload by T2* MRI in a large cohort of well treated thalassemia major patients: Can it tell us heart iron distribution and function?

American Journal of Hematology

Volumn 90, Issue 9, 2015, Pages E189-E190

  Meloni, Antonella ^a   Restaino, Gennaro ^b   Missere, Massimiliano ^b   De Marchi, Daniele ^a   Positano, Vincenzo ^a   Valeri, Gianluca ^c   Giuseppe D'Ascola, Domenico ^d   Peluso, Angelo ^e   Caterina Putti, Maria ^f   Lendini, Maddalena ^g   Giovanna Neri, Maria ^a   Midiri, Massimo ^h   Sallustio, Giuseppina ^b   Pepe, Alessia ^a  

^a FONDAZIONE TOSCANA GABRIELE MONASTERIO   (Italy)

^b Centro di Ricerca e Formazione ad Alta Tecnologia nelle Scienze Biomediche   (Italy)

^c OSPEDALI RIUNITI   (Italy)

^d BIANCHI MELACRINO MORELLI HOSPITAL   (Italy)

^e Azienda Unità Sanitaria Locale TA 1   (Italy)

^f UNIVERSITY OF PADOVA   (Italy)

^g Giovanni Paolo II Hospital   (Italy)

^h UNIVERSITY OF PALERMO   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; GLUCOSE METABOLISM; HEMOSIDEROSIS; HUMAN; IRON OVERLOAD; NUCLEAR MAGNETIC RESONANCE IMAGING; ORAL GLUCOSE TOLERANCE TEST; PANCREAS; PRIORITY JOURNAL; THALASSEMIA; ADULT; ADVERSE EFFECTS; BETA-THALASSEMIA; BLOOD TRANSFUSION; COHORT ANALYSIS; FEMALE; HEART MUSCLE; MALE; METABOLISM; PATHOLOGY;

FERRITIN; IRON;

ADULT; BETA-THALASSEMIA; BLOOD TRANSFUSION; COHORT STUDIES; FEMALE; FERRITINS; HUMANS; IRON; IRON OVERLOAD; MAGNETIC RESONANCE IMAGING; MALE; MYOCARDIUM; PANCREAS;

EID: 84939479984     PISSN: 03618609     EISSN: 10968652     Source Type: Journal    
DOI: 10.1002/ajh.24081     Document Type: Article

References (6)

1. Meloni A, Ramazzotti A, Positano V, et al. Evaluation of a web-based network for reproducible T2* MRI assessment of iron overload in thalassemia. Int J Med Inform 2009;78:503-512.
2. Restaino G, Meloni A, Positano V, et al. Regional and global pancreatic T*(2) MRI for iron overload assessment in a large cohort of healthy subjects: Normal values and correlation with age and gender. Magn Reson Med 2011;65:764-769.
3. Pepe A, Positano V, Santarelli F, et al. Multislice multiecho T2* cardiovascular magnetic resonance for detection of the heterogeneous distribution of myocardial iron overload. J Magn Reson Imaging 2006;23:662-668.
4. Au WY, Lam WW, Chu WW, et al. A cross-sectional magnetic resonance imaging assessment of organ specific hemosiderosis in 180 thalassemia major patients in Hong Kong. Haematologica 2008;93:784-786.
5. Papakonstantinou O, Ladis V, Kostaridou S, et al. The pancreas in beta-thalassemia major: MR imaging features and correlation with iron stores and glucose disturbances. Eur Radiol 2007;17:1535-1543.
6. Noetzli LJ, Papudesi J, Coates TD, Wood JC. Pancreatic iron loading predicts cardiac iron loading in thalassemia major. Blood 2009;114:4021-4026.