Comparing cutaneous research funded by the US National Institutes of Health (NIH) with the US skin disease burden

Journal of the American Academy of Dermatology

Volumn 73, Issue 3, 2015, Pages 383-391.e1

  Hagstrom, Erika L ^a   Patel, Shivani ^b   Karimkhani, Chante ^c   Boyers, Lindsay N ^d   Williams, Hywel C ^e   Hay, Roderick J ^f   Weinstock, Martin A ^g,h,i   Armstrong, April W ^j,k   Dunnick, Cory A ^k,l   Margolis, David J ^m   Dellavalle, Robert P ^j,k,m  

^a LOYOLA UNIVERSITY CHICAGO   (United States)

^b MEDICAL UNIVERSITY OF SOUTH CAROLINA   (United States)

^c Columbia University College of Physicians and Surgeons ^*  (United States)

^d GEORGETOWN UNIVERSITY SCHOOL OF MEDICINE   (United States)

^e UNIVERSITY OF NOTTINGHAM   (United Kingdom)

^f KING S COLLEGE HOSPITAL   (United Kingdom)

^g PROVIDENCE VETERANS AFFAIRS MEDICAL CENTER   (United States)

^h RHODE ISLAND HOSPITAL   (United States)

ⁱ BROWN UNIVERSITY   (United States)

^j UNIVERSITY OF COLORADO SCHOOL OF MEDICINE   (United States)

^k DEPARTMENT OF VETERANS AFFAIRS   (United States)

^l UNIVERSITY OF PENNSYLVANIA   (United States)

^m Food Science and Human Nutrition   (United States)

more..

Author keywords

dermatitis; disability adjusted life years; disease burden; leprosy; melanoma; National Institutes of Health; priority setting; skin conditions

Indexed keywords

ACNE VULGARIS; ALOPECIA AREATA; ARTICLE; CELLULITIS; CROSS-SECTIONAL STUDY; DECUBITUS; DERMATITIS; DERMATOMYCOSIS; DISEASE BURDEN; FUNDING; GENERAL ASPECTS OF DISEASE; HUMAN; LEPROSY; MEDICAL RESEARCH; MELANOMA; NATIONAL HEALTH ORGANIZATION; NON MELANOMA SKIN CANCER; PRIORITY JOURNAL; PRURITUS; PSORIASIS; SCABIES; SKIN DISEASE; UNITED STATES; URTICARIA; VIRAL SKIN DISEASE; COMPARATIVE STUDY; COST OF ILLNESS; DISABILITY; ECONOMICS; FEMALE; FINANCIAL MANAGEMENT; HEALTH; HEALTH CARE COST; MALE; QUALITY ADJUSTED LIFE YEAR; SEVERITY OF ILLNESS INDEX; SKIN DISEASES; SKIN NEOPLASMS;

BIOMEDICAL RESEARCH; COST OF ILLNESS; CROSS-SECTIONAL STUDIES; DISABILITY EVALUATION; FEMALE; GLOBAL HEALTH; HEALTH CARE COSTS; HUMANS; LEPROSY; MALE; MELANOMA; NATIONAL INSTITUTES OF HEALTH (U.S.); QUALITY-ADJUSTED LIFE YEARS; RESEARCH SUPPORT AS TOPIC; SEVERITY OF ILLNESS INDEX; SKIN DISEASES; SKIN NEOPLASMS; UNITED STATES;

EID: 84939468852     PISSN: 01909622     EISSN: 10976787     Source Type: Journal    
DOI: 10.1016/j.jaad.2015.04.039     Document Type: Article

References (47)

1. C.J. Murray, T. Vos, R. Lozano, and et al. Disability-adjusted life years (DALYs) for 291 diseases and injuries in 21 regions, 1990-2010: a systematic analysis for the Global Burden of Disease Study 2010 Lancet 380 9859 2012 2197 2223
2. T. Vos, A.D. Flaxman, M. Naghavi, and et al. Years lived with disability (YLDs) for 1160 sequelae of 289 diseases and injuries 1990-2010: a systematic analysis for the Global Burden of Disease Study 2010 Lancet 380 9859 2012 2163 2196
3. C.J. Murray, M. Ezzati, A.D. Flaxman, and et al. GBD 2010: design, definitions, and metrics Lancet 380 9859 2012 2063 2066
4. US Burden of Disease Collaborators (2013) The state of US health, 1990-2010 burden of diseases, injuries, and risk factors JAMA 310 6 2013 591 608
5. C. Karimkhani, L.N. Boyers, D.J. Margolis, and et al. Comparing cutaneous research funded by the National Institute of Arthritis and Musculoskeletal and Skin Diseases with 2010 Global Burden of Disease results PLoS One 9 7 2014 e102122
6. C. Karimkhani, L.N. Boyers, L. Prescott, and et al. Global burden of skin disease as reflected in Cochrane database of systematic reviews JAMA Dermatol 150 9 2014 945 951
7. IOM (Institute of Medicine) Committee on the NIH Research Priority-Setting Process. Scientific opportunities and public needs: improving priority setting and public input at the National Institutes of Health 1998 National Academies Press Washington (DC)
8. R. Best Disease politics and medical research funding: three ways advocacy shapes policy Am Sociol Rev 77 5 2012 780 803
9. J.B. Rubin, A.D. Paltiel, and W.M. Saltzman Are we studying what matters? Health priorities and NIH-funded biomedical engineering research Ann Biomed Eng 38 7 2010 2237 2251
10. A.J. Carter, and C.N. Nguyen A comparison of cancer burden and research spending reveals discrepancies in the distribution of research funding BMC Public Health 12 2012 526
11. L.A. Gillum, C. Gouveia, E.R. Dorsey, and et al. NIH disease funding levels and burden of disease PLoS One 6 2 2011 e1683
12. H.H. Garrison, and A.M. Deschamps NIH research funding and early career physician scientists: continuing challenges in the 21st century FASEB J 28 3 2014 1049 1058
13. Research Portfolio Online Reporting Tools (RePORT). Brochure. Available at: http://report.nih.gov/brochure/index.html. Accessed March 15, 2015.
14. NIH Office of Extramural Research, Grants and Funding. How to apply. Available at: http://grants.nih.gov/grants/how-to-apply.htm. Accessed March 15, 2015.
15. National Institutes of Health Research Portfolio Online Reporting Tools (RePORT). Funding facts. Available at: http://report.nih.gov/fundingfacts/fundingfacts.aspx. Accessed March 15, 2015.
16. R.J. Hay, N.E. Johns, H.C. Williams, and et al. The global burden of skin disease in 2010: an analysis of the prevalence and impact of skin conditions J Invest Dermatol 134 6 2013 1527 1534
17. C.J.L. Murray, M. Ezzati, A.D. Flaxman, and et al. Supplementary appendix to: GBD 2010: Design, definitions, and metrics Lancet 380 9859 2012 263 266
18. R. Loxano, M. Naghavi, K. Roreman, and et al. Supplementary appendix to global and regional mortality from 235 causes of death for 20 age groups in 1990 and 2010: a systematic analysis for the Global Burden of Disease Study 2010 Lancet 380 2012 2095 2128
19. Institute for Health Metrics and Evaluation. GBD compare. Available at: http://viz.healthmetricsandevaluation.org/gbd-compare/. Accessed March 15, 2015.
20. National Institutes of Health. Institutes, Centers, and Offices. Available at: http://www.nih.gov/icd/. Accessed March 15, 2015.
21. C. Murray, and A. Lopez Measuring the global burden of disease N Engl J Med 369 5 2013 448 457
22. Institute for Health Metrics and Evaluation. The global burden of disease: generating evidence, guiding policy. Available at: http://www.healthdata.org/sites/default/files/files/policy-report/2013/GBD-GeneratingEvidence/IHME-GBD-GeneratingEvidence-FullReport.pdf. Accessed March 30, 2015.
23. L.N. Boyers, C. Karimkhani, M. Naghavi, and et al. Global mortality from conditions with skin manifestations J Am Acad Dermatol 71 6 2014 1137 1143
24. C. Holterhues, L.M. Hollestein, T. Nijsten, E.R. Koomen, W. Nusselder, and E. de Vries Burden of disease due to cutaneous melanoma has increased in the Netherlands since 1991 Br J Dermatol 169 2 2013 389 397
25. OpenSecrets.org Center for Responsive Politics. Melanoma Research Foundation. Available at: http://www.opensecrets.org/lobby/clientsum.php?id=D000053610&year=2012. Accessed March 15, 2015.
26. OpenSecrets.org Center for Responsive Politics. National Psoriasis Foundation. Available at: http://apps.who.int/iris/bitstream/10665/71661/1/wer7744.pdf?ua=1. Accessed April 4, 2015.
27. E. Yim, R.S. Kirsner, R.S. Gailey, D.W. Mandel, S.C. Chen, and M. Tomic-Canic Effect of physical therapy on wound healing and quality of life in patients with venous leg ulcers a systematic review JAMA Dermatol 151 3 2015 320 327
28. K.P. Huang, S. Mullangi, Y. Guo, and A.A. Qureshi Autoimmune, atopic, and mental health comorbid conditions associated with alopecia areata in the United States JAMA Dermatol 149 7 2013 789 794
29. P. Yaghmaie, C.W. Koudelka, and E.L. Simpson Mental health comorbidity in patients with atopic dermatitis J Allergy Clin Immunol 131 2 2013 428 433
30. S. Noh, M. Kim, C.O. Park, S.K. Hann, and S.H. Oh Comparison of the psychological impacts of asymptomatic and symptomatic cutaneous diseases: vitiligo and atopic dermatitis Ann Dermatol 25 4 2013 454 461
31. B. Rehal, and A.W. Armstrong Health outcome measures in atopic dermatitis: a systematic review of trends in disease severity and quality-of-life instruments 1985-2010 PLoS One 6 4 2011 e17520
32. Y. Benyamini, D. Goner-Shilo, and A. Lazarov Illness perception and quality of life in patients with contact dermatitis Contact Dermatitis 67 4 2012 193 199
33. D. Fivenson, R.J. Arnold, D.J. Kaniecki, J.L. Cohen, F. Frech, and A.Y. Finlay The effect of atopic dermatitis on total burden of illness and quality of life on adults and children in a large managed care organization J Manag Care Pharm 8 5 2002 333 342
34. National Eczema Association. NEA funded research. Available at: http://nationaleczema.org/research/nea-funded-research/. Accessed March 15, 2015.
35. American Acne and Rosacea Society. Clinical research grant details. Available at: https://acneandrosacea.org/grants/clinical-research. Accessed March 15, 2015.
36. E.L. Simpson Atopic dermatitis: a review of topical treatment options Curr Med Res Opin 26 3 2010 633 650
37. C. Karimkhani, R. Gonzalez, and R.P. Dellavalle A review of novel therapies for melanoma Am J Clin Dermatol 15 4 2014 323 337
38. I. Roberts, and R. Jackson Beyond disease burden: towards solution-oriented population health Lancet 381 2013 2219 2221
39. I. Chalmers, M.B. Bracken, B. Djulbegovic, and et al. How to increase value and reduce waste when research priorities are set Lancet 338 2014 156 165
40. Rand Corporation. Mental health retrosight: identifying the attributes of successfully translated research (lessons from schizophrenia). Available at: http://www.rand.org/content/dam/rand/pubs/research-briefs/RB9700/RB9738/RAND-RB9738.pdf. Accessed March 30, 2015.
41. P. Pound, and M.B. Bracken Is animal research sufficiently evidence based to be a cornerstone of biomedical research? BMJ 348 2014 g3387
42. B. Cochrane, and K. Byatt A paradigm shift is needed to move biomedical research forward BMJ 349 2014 g4267
43. Institute for Health Metrics and Evaluation. GBD 210 arrow diagram. Available at: http://vizhub.healthdata.org/irank/arrow.php. Accessed March 30, 2015.
44. L.C. Rodrigues, and D.N. Lockwood Leprosy now: epidemiology, progress, challenges, and research gaps Lancet Infect Dis 11 6 2011 464 470
45. D.M. Scollard, L.B. Adams, T.P. Gillis, J.L. Krahenbuhl, R.W. Truman, and D.L. Williams The continuing challenges of leprosy Clin Microbiol Rev 19 2 2006 338 381
46. J.V. Selby, and S.H. Lipstein PCORI at 3 years-progress, lessons, and plans N Engl J Med 370 7 2014 592 595
47. J. Raftery, and J. Powell Health technology assessment in the UK Lancet 382 2013 1278 1285