Leptin-STAT3-G9a signaling promotes obesity-mediated breast cancer progression

Cancer Research

Volumn 75, Issue 11, 2015, Pages 2375-2386

  Chang, Chao Ching ^a,b   Wu, Meng Ju ^a,b   Yang, Jer Yen ^a,b   Camarillo, Ignacio G ^b,c   Chang, Chun Ju ^a,b  

^a PURDUE UNIVERSITY   (United States)

^b Purdue University   (United States)

^c PURDUE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

4 [[(4 METHYLPHENYL)SULFONYLOXY]ACETAMIDO]SALICYLIC ACID; BMI1 PROTEIN; CD24 ANTIGEN; GLYCOGEN SYNTHASE KINASE 3BETA; HEPATOCYTE NUCLEAR FACTOR 3BETA; HERMES ANTIGEN; HISTONE METHYLTRANSFERASE; JANUS KINASE; LEPTIN RECEPTOR; MAMMALIAN TARGET OF RAPAMYCIN; MICRORNA 200C; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; NERVE CELL ADHESION MOLECULE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; OCTAMER TRANSCRIPTION FACTOR 4; PROTEIN KINASE B; PROTEIN P53; STAT1 PROTEIN; TRANSCRIPTION FACTOR NANOG; TRANSCRIPTION FACTOR SOX2; TRANSCRIPTION FACTOR ZEB1; UVOMORULIN; EHMT2 PROTEIN, HUMAN; HISTOCOMPATIBILITY ANTIGEN; HISTONE LYSINE METHYLTRANSFERASE; LEPTIN; MICRORNA; MIRN200 MICRORNA, HUMAN; STAT3 PROTEIN; STAT3 PROTEIN, HUMAN;

3' UNTRANSLATED REGION; ANIMAL CELL; ANIMAL MODEL; ARTICLE; BREAST CANCER; BREAST CANCER CELL LINE; BREAST EPITHELIUM CELL; CANCER GROWTH; CANCER INCIDENCE; CELL DIFFERENTIATION; COCULTURE; COMPLEX FORMATION; CONTROLLED STUDY; DIMERIZATION; DNA BINDING; DOWN REGULATION; EPIGENETICS; EPITHELIAL MESENCHYMAL TRANSITION; FEMALE; GENE EXPRESSION PROFILING; GENE SILENCING; HISTONE MODIFICATION; HUMAN; HUMAN CELL; MAMMARY GLAND FAT; MOUSE; NONHUMAN; OBESITY; PHENOTYPE; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; PROTEIN TARGETING; RAT; SHORT TANDEM REPEAT; SIGNAL TRANSDUCTION; SPINDLE CELL; TRIPLE NEGATIVE BREAST CANCER; TUMOR MICROENVIRONMENT; UPREGULATION; ANIMAL; BIOSYNTHESIS; BREAST NEOPLASMS; CANCER STEM CELL; CARCINOGENESIS; COMPLICATION; EXPERIMENTAL MAMMARY NEOPLASM; GENE EXPRESSION REGULATION; GENETICS; MCF 7 CELL LINE; METABOLISM; PATHOLOGY;

ANIMALS; BREAST NEOPLASMS; CARCINOGENESIS; FEMALE; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION, NEOPLASTIC; HISTOCOMPATIBILITY ANTIGENS; HISTONE-LYSINE N-METHYLTRANSFERASE; HUMANS; LEPTIN; MAMMARY NEOPLASMS, ANIMAL; MCF-7 CELLS; MICE; MICRORNAS; NEOPLASTIC STEM CELLS; OBESITY; RATS; RECEPTORS, LEPTIN; STAT3 TRANSCRIPTION FACTOR;

EID: 84939438451     PISSN: 00085472     EISSN: 15387445     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-14-3076     Document Type: Article

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