-
1
-
-
0034864144
-
Levetiracetam: the preclinical profile of a new class of antiepileptic drugs?
-
Klitgaard H. Levetiracetam: the preclinical profile of a new class of antiepileptic drugs?. Epilepsia 2001, 42(Suppl 4):S13-S18.
-
(2001)
Epilepsia
, vol.42
, Issue.Suppl 4
, pp. S13-S18
-
-
Klitgaard, H.1
-
2
-
-
3042748137
-
The synaptic vesicle protein SV2A is the binding site for the antiepileptic drug levetiracetam
-
Lynch B.A., Lambeng N., Nocka K., Kensel-Hammes P., Bajjalieh S.M., Matagne A., et al. The synaptic vesicle protein SV2A is the binding site for the antiepileptic drug levetiracetam. Proc Natl Acad Sci U S A 2004, 101:9861-9866.
-
(2004)
Proc Natl Acad Sci U S A
, vol.101
, pp. 9861-9866
-
-
Lynch, B.A.1
Lambeng, N.2
Nocka, K.3
Kensel-Hammes, P.4
Bajjalieh, S.M.5
Matagne, A.6
-
3
-
-
0344198468
-
Serum concentrations of levetiracetam in epileptic patients: the influence of dose and co-medication
-
May T.W., Rambeck B., Jürgens U. Serum concentrations of levetiracetam in epileptic patients: the influence of dose and co-medication. Ther Drug Monit 2003, 25:690-699.
-
(2003)
Ther Drug Monit
, vol.25
, pp. 690-699
-
-
May, T.W.1
Rambeck, B.2
Jürgens, U.3
-
4
-
-
0036159535
-
Levetiracetam: a different approach to the pharmacotherapy of epilepsy
-
Welty T.E., Gidal B.E., Ficker D.M., Privitera M.D. Levetiracetam: a different approach to the pharmacotherapy of epilepsy. Ann Pharmacother 2002, 36:296-304.
-
(2002)
Ann Pharmacother
, vol.36
, pp. 296-304
-
-
Welty, T.E.1
Gidal, B.E.2
Ficker, D.M.3
Privitera, M.D.4
-
5
-
-
69749123287
-
Levetiracetam in children with refractory epilepsy: lack of correlation between plasma concentration and efficacy
-
Giroux P.C., Salas-Prato M., Théorêt Y., Carmant L. Levetiracetam in children with refractory epilepsy: lack of correlation between plasma concentration and efficacy. Seizure 2009, 18:559-563.
-
(2009)
Seizure
, vol.18
, pp. 559-563
-
-
Giroux, P.C.1
Salas-Prato, M.2
Théorêt, Y.3
Carmant, L.4
-
6
-
-
0035571150
-
Clinical pharmacology and therapeutic use of the new antiepileptic drugs
-
Perucca E. Clinical pharmacology and therapeutic use of the new antiepileptic drugs. Fundam Clin Pharmacol 2001, 15:405-417.
-
(2001)
Fundam Clin Pharmacol
, vol.15
, pp. 405-417
-
-
Perucca, E.1
-
7
-
-
4644265790
-
Drug selection for the newly diagnosed patient: when is a new generation antiepileptic drug indicated?
-
Tomson T. Drug selection for the newly diagnosed patient: when is a new generation antiepileptic drug indicated?. J Neurol 2004, 251:1043-1049.
-
(2004)
J Neurol
, vol.251
, pp. 1043-1049
-
-
Tomson, T.1
-
8
-
-
33644909875
-
Clinically relevant drug interactions with antiepileptic drugs
-
Perucca E. Clinically relevant drug interactions with antiepileptic drugs. Br J Clin Pharmacol 2006, 61:246-255.
-
(2006)
Br J Clin Pharmacol
, vol.61
, pp. 246-255
-
-
Perucca, E.1
-
9
-
-
35648976607
-
Levetiracetam in the treatment of childhood epilepsy
-
Wheless J.W. Levetiracetam in the treatment of childhood epilepsy. Neuropsychiatr Dis Treat 2007, 3:409-421.
-
(2007)
Neuropsychiatr Dis Treat
, vol.3
, pp. 409-421
-
-
Wheless, J.W.1
-
10
-
-
77952556050
-
Levetiracetam in childhood epilepsy
-
Verrotti A., D'Adamo E., Parisi P., Chiarelli F., Curatolo P. Levetiracetam in childhood epilepsy. Pediatr Drugs 2010, 12:177-186.
-
(2010)
Pediatr Drugs
, vol.12
, pp. 177-186
-
-
Verrotti, A.1
D'Adamo, E.2
Parisi, P.3
Chiarelli, F.4
Curatolo, P.5
-
11
-
-
0033621925
-
Pharmacokinetic profile of levetiracetam: toward ideal characteristics
-
Patsalos P.N. Pharmacokinetic profile of levetiracetam: toward ideal characteristics. Pharmacol Ther 2000, 85:77-85.
-
(2000)
Pharmacol Ther
, vol.85
, pp. 77-85
-
-
Patsalos, P.N.1
-
12
-
-
0035675738
-
Pharmacokinetic study of levetiracetam in children
-
Pellock J.M., Glauser T.A., Bebin E.M., Fountain N.B., Ritter F.J., Coupez R.M., et al. Pharmacokinetic study of levetiracetam in children. Epilepsia 2001, 42:1574-1579.
-
(2001)
Epilepsia
, vol.42
, pp. 1574-1579
-
-
Pellock, J.M.1
Glauser, T.A.2
Bebin, E.M.3
Fountain, N.B.4
Ritter, F.J.5
Coupez, R.M.6
-
13
-
-
35148858500
-
Long-term use of levetiracetam in patients with severe childhood-onset epilepsy
-
von Stuelpnagel C., Holthausen H., Kluger G. Long-term use of levetiracetam in patients with severe childhood-onset epilepsy. Eur J Paediatr Neurol 2007, 11:341-345.
-
(2007)
Eur J Paediatr Neurol
, vol.11
, pp. 341-345
-
-
von Stuelpnagel, C.1
Holthausen, H.2
Kluger, G.3
-
14
-
-
84875895637
-
Efficacy and safety of add-on levetiracetam in refractory childhood epilepsy
-
Kanemura H., Sano F., Tando T., Sugita K., Aihara M. Efficacy and safety of add-on levetiracetam in refractory childhood epilepsy. Brain Dev 2013, 35:386-391.
-
(2013)
Brain Dev
, vol.35
, pp. 386-391
-
-
Kanemura, H.1
Sano, F.2
Tando, T.3
Sugita, K.4
Aihara, M.5
-
15
-
-
13244272154
-
Rapid onset of action of levetiracetam in refractory epilepsy patients
-
French J., Arrigo C. Rapid onset of action of levetiracetam in refractory epilepsy patients. Epilepsia 2005, 46:324-326.
-
(2005)
Epilepsia
, vol.46
, pp. 324-326
-
-
French, J.1
Arrigo, C.2
-
16
-
-
34848887217
-
Therapeutic drug monitoring of levetiracetam by high-performance liquid chromatography with photodiode array ultraviolet detection: preliminary observations on correlation between plasma concentration and clinical response in patients with refractory epilepsy
-
Lancelin F., Franchon E., Kraoul L., Garciau I., Brovedani S., Tabaouti K., et al. Therapeutic drug monitoring of levetiracetam by high-performance liquid chromatography with photodiode array ultraviolet detection: preliminary observations on correlation between plasma concentration and clinical response in patients with refractory epilepsy. Ther Drug Monit 2007, 29:576-583.
-
(2007)
Ther Drug Monit
, vol.29
, pp. 576-583
-
-
Lancelin, F.1
Franchon, E.2
Kraoul, L.3
Garciau, I.4
Brovedani, S.5
Tabaouti, K.6
-
17
-
-
34249807897
-
Pharmacokinetics of levetiracetam in infants and young children with epilepsy
-
Glauser T.A., Mitchell W.G., Weinstock A., Bebin M., Chen D., Coupez R., et al. Pharmacokinetics of levetiracetam in infants and young children with epilepsy. Epilepsia 2007, 48:1117-1122.
-
(2007)
Epilepsia
, vol.48
, pp. 1117-1122
-
-
Glauser, T.A.1
Mitchell, W.G.2
Weinstock, A.3
Bebin, M.4
Chen, D.5
Coupez, R.6
-
18
-
-
33947244366
-
Prospective assessment of levetiracetam pharmacokinetics during dose escalation in 4- to 12-year-old children with partial-onset seizures on concomitant carbamazepine or valproate
-
Fountain N.B., Conry J.A., Rodríguez-Leyva I., Gutierrez-Moctezuma J., Salas E., Coupez R., et al. Prospective assessment of levetiracetam pharmacokinetics during dose escalation in 4- to 12-year-old children with partial-onset seizures on concomitant carbamazepine or valproate. Epilepsy Res 2007, 74:60-69.
-
(2007)
Epilepsy Res
, vol.74
, pp. 60-69
-
-
Fountain, N.B.1
Conry, J.A.2
Rodríguez-Leyva, I.3
Gutierrez-Moctezuma, J.4
Salas, E.5
Coupez, R.6
-
19
-
-
0036159059
-
Dose-response effect of levetiracetam 1000 and 2000mg/day in partial epilepsy
-
Boon P., Chauvel P., Pohlmann-Eden B., Otoul C., Wroe S. Dose-response effect of levetiracetam 1000 and 2000mg/day in partial epilepsy. Epilepsy Res 2002, 48:77-89.
-
(2002)
Epilepsy Res
, vol.48
, pp. 77-89
-
-
Boon, P.1
Chauvel, P.2
Pohlmann-Eden, B.3
Otoul, C.4
Wroe, S.5
-
20
-
-
33747848720
-
Assessment of a dose-response relationship of levetiracetam
-
Meencke H.J., Buyle S. Assessment of a dose-response relationship of levetiracetam. Eur J Neurol 2006, 13:942-946.
-
(2006)
Eur J Neurol
, vol.13
, pp. 942-946
-
-
Meencke, H.J.1
Buyle, S.2
-
21
-
-
84893845065
-
The efficacy of gabapentin in children of partial seizures and the blood levels
-
Nonoda Y., Iwasaki T., Ishii M. The efficacy of gabapentin in children of partial seizures and the blood levels. Brain Dev 2014, 36:194-202.
-
(2014)
Brain Dev
, vol.36
, pp. 194-202
-
-
Nonoda, Y.1
Iwasaki, T.2
Ishii, M.3
-
22
-
-
33745665605
-
N159 Study Group. Double-blind placebo-controlled trial of adjunctive levetiracetam in pediatric partial seizures
-
Glauser T.A., Ayala R., Elterman R.D., Mitchell W.G., Van Orman C.B., Gauer L.J., et al. N159 Study Group. Double-blind placebo-controlled trial of adjunctive levetiracetam in pediatric partial seizures. Neurology 2006, 66:1654-1660.
-
(2006)
Neurology
, vol.66
, pp. 1654-1660
-
-
Glauser, T.A.1
Ayala, R.2
Elterman, R.D.3
Mitchell, W.G.4
Van Orman, C.B.5
Gauer, L.J.6
-
23
-
-
84939289759
-
-
Silver Spring: NDA 21035/S-089 & NDA 21505/S-030 Keppra tablet and oral solution FDA Approved Labeling text dated Jul 2013. Available from:
-
Food and Drug Administration [Internet]. Silver Spring: NDA 21035/S-089 & NDA 21505/S-030 Keppra tablet and oral solution FDA Approved Labeling text dated Jul 2013. Available from: http://www.accessdata.fda.gov/scripts/cder/drugsatfda/.
-
-
-
-
24
-
-
0026471112
-
Ucb L059, a novel anti-convulsant drug: pharmacological profile in animals
-
Gower A.J., Noyer M., Verloes R., Gobert J., Wülfert E. Ucb L059, a novel anti-convulsant drug: pharmacological profile in animals. Eur J Pharmacol 1992, 222:193-203.
-
(1992)
Eur J Pharmacol
, vol.222
, pp. 193-203
-
-
Gower, A.J.1
Noyer, M.2
Verloes, R.3
Gobert, J.4
Wülfert, E.5
-
25
-
-
0033854805
-
Levetiracetam for partial seizures: results of a double-blind, randomized clinical trial
-
Cereghino J.J., Biton V., Abou-Khalil B., Dreifuss F., Gauer L.J., Leppik I. Levetiracetam for partial seizures: results of a double-blind, randomized clinical trial. Neurology 2000, 55:236-242.
-
(2000)
Neurology
, vol.55
, pp. 236-242
-
-
Cereghino, J.J.1
Biton, V.2
Abou-Khalil, B.3
Dreifuss, F.4
Gauer, L.J.5
Leppik, I.6
-
26
-
-
0033775210
-
Efficacy and tolerability of levetiracetam 3000 mg/d in patients with refractory partial seizures: a multicenter, double-blind, responder-selected study evaluating monotherapy
-
Ben-Menachem E., Falter U. Efficacy and tolerability of levetiracetam 3000 mg/d in patients with refractory partial seizures: a multicenter, double-blind, responder-selected study evaluating monotherapy. Epilepsia 2000, 41:1276-1283.
-
(2000)
Epilepsia
, vol.41
, pp. 1276-1283
-
-
Ben-Menachem, E.1
Falter, U.2
|