A comparison of the pathogenesis of marburg virus disease in humans and nonhuman primates and evaluation of the suitability of these animal models for predicting clinical efficacy under the -animal rule'

Comparative Medicine

Volumn 65, Issue 3, 2015, Pages 241-259

  Glaze, Elizabeth R ^a   Roy, Michael J ^b   Dalrymple, Lonnie W ^b   Lanning, Lynda L ^a  

^a NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

^b FREDERICK NATIONAL LABORATORY FOR CANCER RESEARCH   (United States)

Author keywords

HD; High dose; LD; Low dose; Marburg virus; Marburg virus disease; MARV; MVD; Ravn virus; RAVV

Indexed keywords

ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; CIPROFLOXACIN; CREATINE;

ABDOMINAL PAIN; ADOLESCENT; ANGOLA; ANIMAL EXPERIMENT; ANIMAL MODEL; AUTOPSY; BLOOD CLOTTING DISORDER; BRAIN DISEASE; CHILL; CHLOROCEBUS AETHIOPS; CLINICAL ARTICLE; CONFUSION; CONGO; CONTROLLED STUDY; DIARRHEA; DISSEMINATED INTRAVASCULAR CLOTTING; ELECTRON MICROSCOPY; FATIGUE; FEMALE; GERMAN FEDERAL REPUBLIC; HEADACHE; HUMAN; LABORATORY TEST; LEUKOPENIA; MACACA FASCICULARIS; MALE; MARBURG HEMORRHAGIC FEVER; MYOSITIS; NAUSEA; NONHUMAN; PANCREATITIS; PANCYTOPENIA; PREDICTION; PRIMATE; RECTUM HEMORRHAGE; REVIEW; RHESUS MONKEY; SOUTH AFRICA; UNITED STATES; VIRUS VIRULENCE; VOMITING; WEAKNESS; YUGOSLAVIA; ANIMAL; COMPARATIVE STUDY; DISEASE MODEL; HAPLORHINI; PATHOPHYSIOLOGY; VIROLOGY;

ANIMALS; DISEASE MODELS, ANIMAL; HAPLORHINI; HUMANS; MARBURG VIRUS DISEASE;

EID: 84939246404     PISSN: 15320820     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

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