Intrathecal overproduction of proinflammatory cytokines and chemokines in febrile infection-related refractory status epilepticus

Journal of Neurology, Neurosurgery and Psychiatry

Volumn 86, Issue 7, 2015, Pages 820-822

  Sakuma, Hiroshi ^a   Tanuma, Naoyuki ^a,b   Kuki, Ichiro ^c   Takahashi, Yukitoshi ^d   Shiomi, Masashi ^e   Hayashi, Masaharu ^a  

^a TOKYO METROPOLITAN INSTITUTE OF MEDICAL SCIENCE   (Japan)

^b Tokyo Metropolitan Fuchu Medical Center for the Disabled   (Japan)

^c OSAKA CITY GENERAL HOSPITAL   (Japan)

^d SHIZUOKA INSTITUTE OF EPILEPSY AND NEUROLOGICAL DISORDERS   (Japan)

^e Aizenbashi Hospital   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CHEMOKINE; COLONY STIMULATING FACTOR RECEPTOR; CXCL1 CHEMOKINE; CXCL9 CHEMOKINE; CYTOKINE; EOTAXIN 3; GAMMA INTERFERON INDUCIBLE PROTEIN 10; INTERLEUKIN 6; INTERLEUKIN 8; MONOCYTE CHEMOTACTIC PROTEIN 4; STROMAL CELL DERIVED FACTOR 1; CXCL10 PROTEIN, HUMAN;

ANALYTICAL EQUIPMENT; ARTICLE; BLOOD ANALYSIS; CLINICAL ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; EPILEPTIC STATE; FEBRILE INFECTION RELATED STATUS EPILEPTICUS; FEVER; HUMAN; INFECTION; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN CEREBROSPINAL FLUID LEVEL; SUSPENSION ARRAY SYSTEM; UPREGULATION; ADOLESCENT; BLOOD; CEREBROSPINAL FLUID; CHILD; COMPLICATION; FEBRILE CONVULSION; FEMALE; INFANT; MALE; PATHOPHYSIOLOGY; PHYSIOLOGY; PRESCHOOL CHILD; STATUS EPILEPTICUS;

ADOLESCENT; CHEMOKINE CXCL10; CHEMOKINES; CHILD; CHILD, PRESCHOOL; CYTOKINES; FEMALE; HUMANS; INFANT; INTERLEUKIN-6; INTERLEUKIN-8; MALE; SEIZURES, FEBRILE; STATUS EPILEPTICUS;

EID: 84939231232     PISSN: 00223050     EISSN: 1468330X     Source Type: Journal    
DOI: 10.1136/jnnp-2014-309388     Document Type: Article

References (5)

1. Nabbout R, Vezzani A, Dulac O, et al. Acute encephalopathy with inflammation-mediated status epilepticus. Lancet Neurol 2011; 10: 99-108.
2. Sakuma H, Awaya Y, Shiomi M, et al. Acute encephalitis with refractory, repetitive partial seizures (AERRPS): a peculiar form of childhood encephalitis. Acta Neurol Scand 2010; 121: 251-6.
3. van Baalen A, Hausler M, Boor R, et al. Febrile infection-related epilepsy syndrome (FIRES): a nonencephalitic encephalopathy in childhood. Epilepsia 2010; 51: 1323-8.
4. Vezzani A, French J, Bartfai T, et al. The role of inflammation in epilepsy. Nat Rev Neurol 2011; 7: 31-40.
5. Kramer U, Chi CS, Lin KL, et al. Febrile infection-related epilepsy syndrome (FIRES): pathogenesis, treatment, and outcome: a multicenter study on 77 children. Epilepsia 2011; 52: 1956-65.