P2Y2and Gq /G11 control blood pressure by mediating endothelial mechanotransduction

Journal of Clinical Investigation

Volumn 125, Issue 8, 2015, Pages 3077-3086

  Wang, ShengPeng ^a   Iring, András ^a,b   Strilic, Boris ^a   Juárez, Julián Albarrán ^a   Kaur, Harmandeep ^a   Troidl, Kerstin ^a,c   Tonack, Sarah ^a   Burbiel, Joachim C ^d   Müller, Christa E ^d   Fleming, Ingrid ^e   Lundberg, Jon O ^f   Wettschureck, Nina ^a,e   Offermanns, Stefan ^a,e  

^a MAX PLANCK INSTITUTE FOR HEART AND LUNG RESEARCH   (Germany)

^b SEMMELWEIS UNIVERSITY   (Hungary)

^c UNIVERSITY HOSPITAL FRANKFURT   (Germany)

^d UNIVERSITY OF BONN   (Germany)

^e GOETHE UNIVERSITY   (Germany)

^f KAROLINSKA INSTITUTE   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATE; CALCIUM ION; G11 PROTEIN; GQ PROTEIN; GUANINE NUCLEOTIDE BINDING PROTEIN; NITRIC OXIDE SYNTHASE; PURINERGIC P2Y2 RECEPTOR; UNCLASSIFIED DRUG; ENDOTHELIAL NITRIC OXIDE SYNTHASE; GUANINE NUCLEOTIDE BINDING PROTEIN ALPHA SUBUNIT; NITRIC OXIDE; NOS3 PROTEIN, HUMAN; NOS3 PROTEIN, MOUSE; VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR-2, HUMAN; VASCULOTROPIN RECEPTOR 2; VEGFR2 PROTEIN, MOUSE;

ANIMAL CELL; ANIMAL MODEL; ARTERIAL PRESSURE; ARTERY DILATATION; ARTERY ENDOTHELIUM; ARTICLE; BLOOD PRESSURE REGULATION; BLOOD VESSEL TONE; BOVINE MODEL; CALCIUM TRANSPORT; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; HUMAN; HUMAN CELL; HYPERTENSION; IN VITRO STUDY; MECHANOTRANSDUCTION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SHEAR STRESS; ANIMAL; BLOOD PRESSURE; BOVINE; CALCIUM SIGNALING; CYTOLOGY; GENETICS; KNOCKOUT MOUSE; METABOLISM; PATHOLOGY; PHYSIOLOGY; UMBILICAL VEIN ENDOTHELIAL CELL; VASODILATATION;

ANIMALS; BLOOD PRESSURE; CALCIUM SIGNALING; CATTLE; GTP-BINDING PROTEIN ALPHA SUBUNITS, GQ-G11; HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS; HUMANS; HYPERTENSION; MECHANOTRANSDUCTION, CELLULAR; MICE; MICE, KNOCKOUT; NITRIC OXIDE; NITRIC OXIDE SYNTHASE TYPE III; RECEPTORS, PURINERGIC P2Y2; VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR-2; VASODILATION;

EID: 84939216809     PISSN: 00219738     EISSN: 15588238     Source Type: Journal    
DOI: 10.1172/JCI81067     Document Type: Article

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