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Volumn 349, Issue 6248, 2015, Pages 650-655
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TDP-43 repression of nonconserved cryptic exons is compromised in ALS-FTD
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Author keywords
[No Author keywords available]
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Indexed keywords
MESSENGER RNA;
RNA BINDING PROTEIN;
TAR DNA BINDING PROTEIN;
ATG4B PROTEIN, HUMAN;
CYSTEINE PROTEINASE;
DNA BINDING PROTEIN;
ISOPROTEIN;
TDP-43 PROTEIN, HUMAN;
TDP-43 PROTEIN, MOUSE;
BRAIN;
CELLS AND CELL COMPONENTS;
CYTOPLASM;
DISEASE;
GENE EXPRESSION;
NEUROLOGY;
PATHOLOGY;
PROTEIN;
ALTERNATIVE RNA SPLICING;
AMINO ACID SEQUENCE;
AMYOTROPHIC LATERAL SCLEROSIS;
ANIMAL CELL;
ARTICLE;
BRAIN TISSUE;
CELL DEATH;
CONTROLLED STUDY;
DINUCLEOTIDE REPEAT;
EMBRYO;
EMBRYONIC STEM CELL;
EXON;
FRONTOTEMPORAL DEMENTIA;
GENE DELETION;
GENE REPRESSION;
HUMAN;
HUMAN CELL;
INTRON;
MOUSE;
NONHUMAN;
NONSENSE MEDIATED MRNA DECAY;
NUCLEAR IMPORT;
NUCLEAR LOCALIZATION SIGNAL;
POLYADENYLATION;
PRIORITY JOURNAL;
PROTEIN DEPLETION;
REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;
RNA SEQUENCE;
SPLICING DEFECT;
STOP CODON;
TDP 43 PROTEINOPATHY;
TRANSCRIPTION INITIATION SITE;
ANIMAL;
CELL CULTURE;
DNA SEQUENCE;
GENE INACTIVATION;
GENETICS;
HELA CELL LINE;
METABOLISM;
MOLECULAR GENETICS;
NUCLEOTIDE SEQUENCE;
PHYSIOLOGY;
RNA SPLICING;
RNA STABILITY;
AMYOTROPHIC LATERAL SCLEROSIS;
ANIMALS;
BASE SEQUENCE;
CELLS, CULTURED;
CYSTEINE ENDOPEPTIDASES;
DNA-BINDING PROTEINS;
EMBRYONIC STEM CELLS;
EXONS;
FRONTOTEMPORAL DEMENTIA;
GENE KNOCKOUT TECHNIQUES;
HELA CELLS;
HUMANS;
MICE;
MOLECULAR SEQUENCE DATA;
PROTEIN ISOFORMS;
RNA SPLICING;
RNA STABILITY;
RNA, MESSENGER;
SEQUENCE ANALYSIS, DNA;
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EID: 84939170225
PISSN: 00368075
EISSN: 10959203
Source Type: Journal
DOI: 10.1126/science.aab0983 Document Type: Article |
Times cited : (377)
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References (27)
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