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Volumn 137, Issue 8, 2015, Pages 1870-1878

Thyroid cancer GWAS identifies 10q26.12 and 6q14.1 as novel susceptibility loci and reveals genetic heterogeneity among populations

(21)  Mancikova, Veronika a   Cruz, Raquel b   Inglada Pérez, Lucía a,c   Fernández Rozadilla, Ceres b,d   Landa, Iñigo e   Cameselle Teijeiro, José f   Celeiro, Catuxa b   Pastor, Susana g   Velázquez, Antonia g   Marcos, Ricard g,h   Andía, Victor i   Álvarez Escolá, Cristina j   Meoro, Amparo k   Schiavi, Francesca l   Opocher, Giuseppe l,m   Quintela, Inés f   Ansede Bermejo, Juan f   Ruiz Ponte, Clara b   Santisteban, Pilar n   Robledo, Mercedes a   more..


Author keywords

FOXE1; genetic heterogeneity; HTR1B; susceptibility; thyroid cancer

Indexed keywords

ADOLESCENT; ADULT; AGED; ARTICLE; CANCER RISK; CANCER SUSCEPTIBILITY; CASE CONTROL STUDY; CHILD; CHROMOSOME 10Q; CHROMOSOME 6Q; CONTROLLED STUDY; DIFFERENTIATED THYROID CANCER; FEMALE; FORKHEAD BOX PROTEIN E1 GENE; GENE; GENETIC ASSOCIATION; GENETIC HETEROGENEITY; GENETIC RISK; GENETIC SUSCEPTIBILITY; HUMAN; HUMAN TISSUE; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; SINGLE NUCLEOTIDE POLYMORPHISM; SOUTHERN EUROPEAN; SPANIARD; THYROID CANCER; THYROID FOLLICULAR CARCINOMA; THYROID PAPILLARY CARCINOMA; CHROMOSOME 10; CHROMOSOME 6; GENETIC PREDISPOSITION; GENETICS; MIDDLE AGED; SPAIN; THYROID TUMOR; VERY ELDERLY; YOUNG ADULT;

EID: 84938997018     PISSN: 00207136     EISSN: 10970215     Source Type: Journal    
DOI: 10.1002/ijc.29557     Document Type: Article
Times cited : (42)

References (42)
  • 1
    • 0037052644 scopus 로고    scopus 로고
    • Environmental and heritable causes of cancer among 9.6 million individuals in the Swedish Family-cancer database
    • Czene K, Lichtenstein P, Hemminki K,. Environmental and heritable causes of cancer among 9.6 million individuals in the Swedish Family-cancer database. Int J Cancer 2002; 99: 260-6.
    • (2002) Int J Cancer , vol.99 , pp. 260-266
    • Czene, K.1    Lichtenstein, P.2    Hemminki, K.3
  • 2
    • 0035111013 scopus 로고    scopus 로고
    • Familial occurrence of nonmedullary thyroid cancer: A population-based study of 5673 first-degree relatives of thyroid cancer patients from Norway
    • Frich L, Glattre E, Akslen LA,. Familial occurrence of nonmedullary thyroid cancer: a population-based study of 5673 first-degree relatives of thyroid cancer patients from Norway. Cancer Epidemiol Biomarkers Prev 2001; 10: 113-17.
    • (2001) Cancer Epidemiol Biomarkers Prev , vol.10 , pp. 113-117
    • Frich, L.1    Glattre, E.2    Akslen, L.A.3
  • 3
    • 0034927358 scopus 로고    scopus 로고
    • The genetic epidemiology of cancer: Interpreting family and twin studies and their implications for molecular genetic approaches
    • Risch N,. The genetic epidemiology of cancer: interpreting family and twin studies and their implications for molecular genetic approaches. Cancer Epidemiol Biomarkers Prev 2001; 10: 733-41.
    • (2001) Cancer Epidemiol Biomarkers Prev , vol.10 , pp. 733-741
    • Risch, N.1
  • 4
    • 57349123714 scopus 로고    scopus 로고
    • Mapping a new familial thyroid epithelial neoplasia susceptibility locus to chromosome 8p23.1-p22 by high-density single-nucleotide polymorphism genome-wide linkage analysis
    • Cavaco BM, Batista PF, Sobrinho LG, et al., Mapping a new familial thyroid epithelial neoplasia susceptibility locus to chromosome 8p23.1-p22 by high-density single-nucleotide polymorphism genome-wide linkage analysis. J Clin Endocrinol Metab 2008; 93: 4426-30.
    • (2008) J Clin Endocrinol Metab , vol.93 , pp. 4426-4430
    • Cavaco, B.M.1    Batista, P.F.2    Sobrinho, L.G.3
  • 5
    • 58349088314 scopus 로고    scopus 로고
    • A susceptibility locus for papillary thyroid carcinoma on chromosome 8q24
    • He H, Nagy R, Liyanarachchi S, et al., A susceptibility locus for papillary thyroid carcinoma on chromosome 8q24. Cancer Res 2009; 69: 625-31.
    • (2009) Cancer Res , vol.69 , pp. 625-631
    • He, H.1    Nagy, R.2    Liyanarachchi, S.3
  • 6
    • 0034455744 scopus 로고    scopus 로고
    • Papillary thyroid carcinoma associated with papillary renal neoplasia: Genetic linkage analysis of a distinct heritable tumor syndrome
    • Malchoff CD, Sarfarazi M, Tendler B, et al., Papillary thyroid carcinoma associated with papillary renal neoplasia: genetic linkage analysis of a distinct heritable tumor syndrome. J Clin Endocrinol Metab 2000; 85: 1758-64.
    • (2000) J Clin Endocrinol Metab , vol.85 , pp. 1758-1764
    • Malchoff, C.D.1    Sarfarazi, M.2    Tendler, B.3
  • 7
    • 0034917504 scopus 로고    scopus 로고
    • Localization of a susceptibility gene for familial nonmedullary thyroid carcinoma to chromosome 2q21
    • McKay JD, Lesueur F, Jonard L, et al., Localization of a susceptibility gene for familial nonmedullary thyroid carcinoma to chromosome 2q21. Am J Hum Genet 2001; 69: 440-6.
    • (2001) Am J Hum Genet , vol.69 , pp. 440-446
    • McKay, J.D.1    Lesueur, F.2    Jonard, L.3
  • 8
    • 70549089107 scopus 로고    scopus 로고
    • Distinct loci on chromosome 1q21 and 6q22 predispose to familial nonmedullary thyroid cancer: A SNP array-based linkage analysis of 38 families
    • Suh I, Filetti S, Vriens MR, et al., Distinct loci on chromosome 1q21 and 6q22 predispose to familial nonmedullary thyroid cancer: a SNP array-based linkage analysis of 38 families. Surgery 2009; 146: 1073-80.
    • (2009) Surgery , vol.146 , pp. 1073-1080
    • Suh, I.1    Filetti, S.2    Vriens, M.R.3
  • 9
    • 80054122603 scopus 로고    scopus 로고
    • Association studies in thyroid cancer susceptibility: Are we on the right track?
    • Landa I, Robledo M,. Association studies in thyroid cancer susceptibility: are we on the right track? J Mol Endocrinol 2011; 47: R43-R58.
    • (2011) J Mol Endocrinol , vol.47 , pp. R43-R58
    • Landa, I.1    Robledo, M.2
  • 10
    • 84884508113 scopus 로고    scopus 로고
    • An epistatic interaction between the pax8 and STK17B genes in papillary thyroid cancer susceptibility
    • Landa I, Boullosa C, Inglada-Perez L, et al., An epistatic interaction between the pax8 and STK17B genes in papillary thyroid cancer susceptibility. PLoS One 2013; 8: e74765
    • (2013) PLoS One , vol.8 , pp. e74765
    • Landa, I.1    Boullosa, C.2    Inglada-Perez, L.3
  • 11
    • 84908162497 scopus 로고    scopus 로고
    • Detecting epistasis in human complex traits
    • Wei WH, Hemani G, Haley CS,. Detecting epistasis in human complex traits. Nat Rev Genet 2014; 15: 722-33.
    • (2014) Nat Rev Genet , vol.15 , pp. 722-733
    • Wei, W.H.1    Hemani, G.2    Haley, C.S.3
  • 12
    • 33846783311 scopus 로고    scopus 로고
    • Smoking and susceptibility to thyroid cancer: An inverse association with cyp1a1 allelic variants
    • Bufalo NE, Leite JL, Guilhen AC, et al., Smoking and susceptibility to thyroid cancer: an inverse association with cyp1a1 allelic variants. Endocr Relat Cancer 2006; 13: 1185-93.
    • (2006) Endocr Relat Cancer , vol.13 , pp. 1185-1193
    • Bufalo, N.E.1    Leite, J.L.2    Guilhen, A.C.3
  • 13
    • 43949134907 scopus 로고    scopus 로고
    • Genetic polymorphisms associated with cigarette smoking and the risk of graves' disease
    • Bufalo NE, Santos RB, Cury AN, et al., Genetic polymorphisms associated with cigarette smoking and the risk of graves' disease. Clin Endocrinol (Oxf) 2008; 68: 982-7.
    • (2008) Clin Endocrinol (Oxf) , vol.68 , pp. 982-987
    • Bufalo, N.E.1    Santos, R.B.2    Cury, A.N.3
  • 15
    • 77953586698 scopus 로고    scopus 로고
    • Allelic variant at -79 (C>T) in CDKN1B (p27kip1) confers an increased risk of thyroid cancer and alters mRNA levels
    • Landa I, Montero-Conde C, Malanga D, et al., Allelic variant at -79 (C>T) in CDKN1B (p27kip1) confers an increased risk of thyroid cancer and alters mRNA levels. Endocr Relat Cancer 2010; 17: 317-28.
    • (2010) Endocr Relat Cancer , vol.17 , pp. 317-328
    • Landa, I.1    Montero-Conde, C.2    Malanga, D.3
  • 16
    • 70349690194 scopus 로고    scopus 로고
    • The variant rs1867277 in foxe1 gene confers thyroid cancer susceptibility through the recruitment of USF1/USF2 transcription factors
    • Landa I, Ruiz-Llorente S, Montero-Conde C, et al., The variant rs1867277 in foxe1 gene confers thyroid cancer susceptibility through the recruitment of USF1/USF2 transcription factors. PLoS Genet 2009; 5: e1000637.
    • (2009) PLoS Genet , vol.5 , pp. e1000637
    • Landa, I.1    Ruiz-Llorente, S.2    Montero-Conde, C.3
  • 17
    • 84862777075 scopus 로고    scopus 로고
    • Discovery of common variants associated with low TSH levels and thyroid cancer risk
    • Gudmundsson J, Sulem P, Gudbjartsson DF, et al., Discovery of common variants associated with low TSH levels and thyroid cancer risk. Nat Genet 2012; 44: 319-22.
    • (2012) Nat Genet , vol.44 , pp. 319-322
    • Gudmundsson, J.1    Sulem, P.2    Gudbjartsson, D.F.3
  • 18
    • 63449092713 scopus 로고    scopus 로고
    • Common variants on 9q22.33 and 14q13.3 predispose to thyroid cancer in european populations
    • Gudmundsson J, Sulem P, Gudbjartsson DF, et al., Common variants on 9q22.33 and 14q13.3 predispose to thyroid cancer in european populations. Nat Genet 2009; 41: 460-4.
    • (2009) Nat Genet , vol.41 , pp. 460-464
    • Gudmundsson, J.1    Sulem, P.2    Gudbjartsson, D.F.3
  • 19
    • 84885235141 scopus 로고    scopus 로고
    • Genome-wide association study on differentiated thyroid cancer
    • Kohler A, Chen B, Gemignani F, et al., Genome-wide association study on differentiated thyroid cancer. J Clin Endocrinol Metab 2013; 98: E1674-E1681.
    • (2013) J Clin Endocrinol Metab , vol.98 , pp. E1674-E1681
    • Kohler, A.1    Chen, B.2    Gemignani, F.3
  • 20
    • 77955301455 scopus 로고    scopus 로고
    • The foxe1 locus is a major genetic determinant for radiation-related thyroid carcinoma in chernobyl
    • Takahashi M, Saenko VA, Rogounovitch TI, et al., The foxe1 locus is a major genetic determinant for radiation-related thyroid carcinoma in chernobyl. Hum Mol Genet 2010; 19: 2516-23.
    • (2010) Hum Mol Genet , vol.19 , pp. 2516-2523
    • Takahashi, M.1    Saenko, V.A.2    Rogounovitch, T.I.3
  • 21
    • 34548292504 scopus 로고    scopus 로고
    • PLINK: A tool set for whole-genome association and population-based linkage analyses
    • Purcell S, Neale B, Todd-Brown K, et al., PLINK: a tool set for whole-genome association and population-based linkage analyses. Am J Hum Genet 2007; 81: 559-75.
    • (2007) Am J Hum Genet , vol.81 , pp. 559-575
    • Purcell, S.1    Neale, B.2    Todd-Brown, K.3
  • 22
    • 84857595209 scopus 로고    scopus 로고
    • GDF: Dealing with high-throughput genotyping multiplatform data for medical and population genetic applications
    • Amigo J, Salas A, Costas J, et al., GDF: dealing with high-throughput genotyping multiplatform data for medical and population genetic applications. J Proteomics Bioinformatics 2012; 5: 1-6.
    • (2012) J Proteomics Bioinformatics , vol.5 , pp. 1-6
    • Amigo, J.1    Salas, A.2    Costas, J.3
  • 23
    • 67650468322 scopus 로고    scopus 로고
    • Polymorphisms of DNA damage response genes in radiation-related and sporadic papillary thyroid carcinoma
    • Akulevich NM, Saenko VA, Rogounovitch TI, et al., Polymorphisms of DNA damage response genes in radiation-related and sporadic papillary thyroid carcinoma. Endocr Relat Cancer 2009; 16: 491-503.
    • (2009) Endocr Relat Cancer , vol.16 , pp. 491-503
    • Akulevich, N.M.1    Saenko, V.A.2    Rogounovitch, T.I.3
  • 24
    • 84860306298 scopus 로고    scopus 로고
    • Thyroid cancer susceptibility polymorphisms: Confirmation of loci on chromosomes 9q22 and 14q13, validation of a recessive 8q24 locus and failure to replicate a locus on 5q24
    • Jones AM, Howarth KM, Martin L, et al., Thyroid cancer susceptibility polymorphisms: confirmation of loci on chromosomes 9q22 and 14q13, validation of a recessive 8q24 locus and failure to replicate a locus on 5q24. J Med Genet 2012; 49: 158-63.
    • (2012) J Med Genet , vol.49 , pp. 158-163
    • Jones, A.M.1    Howarth, K.M.2    Martin, L.3
  • 25
    • 62649155943 scopus 로고    scopus 로고
    • A unified approach to genotype imputation and haplotype-phase inference for large data sets of trios and unrelated individuals
    • Browning BL, Browning SR,. A unified approach to genotype imputation and haplotype-phase inference for large data sets of trios and unrelated individuals. Am J Hum Genet 2009; 84: 210-23.
    • (2009) Am J Hum Genet , vol.84 , pp. 210-223
    • Browning, B.L.1    Browning, S.R.2
  • 26
    • 84959801619 scopus 로고
    • Statistical aspects of the analysis of data from retrospective studies of disease
    • Mantel N, Haenszel W,. Statistical aspects of the analysis of data from retrospective studies of disease. J Natl Cancer Inst 1959; 22: 719-48.
    • (1959) J Natl Cancer Inst , vol.22 , pp. 719-748
    • Mantel, N.1    Haenszel, W.2
  • 27
    • 80051499915 scopus 로고    scopus 로고
    • Rare-variant association testing for sequencing data with the sequence kernel association test
    • Wu MC, Lee S, Cai T, et al., Rare-variant association testing for sequencing data with the sequence kernel association test. Am J Hum Genet 2011; 89: 82-93.
    • (2011) Am J Hum Genet , vol.89 , pp. 82-93
    • Wu, M.C.1    Lee, S.2    Cai, T.3
  • 28
    • 13444268381 scopus 로고    scopus 로고
    • Cancer as a complex phenotype: Pattern of cancer distribution within and beyond the nuclear family
    • Amundadottir LT, Thorvaldsson S, Gudbjartsson DF, et al., Cancer as a complex phenotype: pattern of cancer distribution within and beyond the nuclear family. PLoS Med 2004; 1: e65
    • (2004) PLoS Med , vol.1 , pp. e65
    • Amundadottir, L.T.1    Thorvaldsson, S.2    Gudbjartsson, D.F.3
  • 29
    • 84907662220 scopus 로고    scopus 로고
    • Novel genome-wide association study-based candidate loci for differentiated thyroid cancer risk
    • Figlioli G, Kohler A, Chen B, et al., Novel genome-wide association study-based candidate loci for differentiated thyroid cancer risk. J Clin Endocrinol Metab 2014; 99: E2084-E2092.
    • (2014) J Clin Endocrinol Metab , vol.99 , pp. E2084-E2092
    • Figlioli, G.1    Kohler, A.2    Chen, B.3
  • 30
    • 84878885949 scopus 로고    scopus 로고
    • Enhanced localization of genetic samples through linkage-disequilibrium correction
    • Baran Y, Quintela I, Carracedo A, et al., Enhanced localization of genetic samples through linkage-disequilibrium correction. Am J Hum Genet 2013; 92: 882-94.
    • (2013) Am J Hum Genet , vol.92 , pp. 882-894
    • Baran, Y.1    Quintela, I.2    Carracedo, A.3
  • 31
    • 84860184315 scopus 로고    scopus 로고
    • Characterization of gene-environment interactions for colorectal cancer susceptibility loci. Cancer
    • Hutter CM, Chang-Claude J, Slattery ML, et al., Characterization of gene-environment interactions for colorectal cancer susceptibility loci. Cancer Res 2012; 72: 2036-44.
    • (2012) Res , vol.72 , pp. 2036-2044
    • Hutter, C.M.1    Chang-Claude, J.2    Slattery, M.L.3
  • 32
    • 17644444777 scopus 로고    scopus 로고
    • The R71G brca1 is a founder Spanish mutation and leads to aberrant splicing of the transcript
    • Vega A, Campos B, Bressac-De-Paillerets B, et al., The R71G brca1 is a founder spanish mutation and leads to aberrant splicing of the transcript. Hum Mutat 2001; 17: 520-1.
    • (2001) Hum Mutat , vol.17 , pp. 520-521
    • Vega, A.1    Campos, B.2    Bressac-De-Paillerets, B.3
  • 33
    • 37549056200 scopus 로고    scopus 로고
    • The emerging landscape of breast cancer susceptibility
    • Stratton MR, Rahman N,. The emerging landscape of breast cancer susceptibility. Nat Genet 2008; 40: 17-22.
    • (2008) Nat Genet , vol.40 , pp. 17-22
    • Stratton, M.R.1    Rahman, N.2
  • 34
    • 84959227849 scopus 로고    scopus 로고
    • Common non-synonymous SNPs associated with breast cancer susceptibility: Findings from the breast cancer association consortium
    • Milne RL, Burwinkel B, Michailidou K, et al., Common non-synonymous SNPs associated with breast cancer susceptibility: findings from the breast cancer association consortium. Hum Mol Genet 2014; 23: 6096-111.
    • (2014) Hum Mol Genet , vol.23 , pp. 6096-6111
    • Milne, R.L.1    Burwinkel, B.2    Michailidou, K.3
  • 35
    • 0035974930 scopus 로고    scopus 로고
    • A novel member of the WD-repeat gene family, wdr11, maps to the 10q26 region and is disrupted by a chromosome translocation in human glioblastoma cells
    • Chernova OB, Hunyadi A, Malaj E, et al., A novel member of the WD-repeat gene family, wdr11, maps to the 10q26 region and is disrupted by a chromosome translocation in human glioblastoma cells. Oncogene 2001; 20: 5378-92.
    • (2001) Oncogene , vol.20 , pp. 5378-5392
    • Chernova, O.B.1    Hunyadi, A.2    Malaj, E.3
  • 36
    • 84859990709 scopus 로고    scopus 로고
    • Expression of serotonin receptors 5-HT1A, 5-HT1B, 5-HT2B and 5-ht4 in ovary and in ovarian tumours
    • Henriksen R, Dizeyi N, Abrahamsson PA,. Expression of serotonin receptors 5-HT1A, 5-HT1B, 5-HT2B and 5-ht4 in ovary and in ovarian tumours. Anticancer Res 2012; 32: 1361-6.
    • (2012) Anticancer Res , vol.32 , pp. 1361-1366
    • Henriksen, R.1    Dizeyi, N.2    Abrahamsson, P.A.3
  • 37
    • 84875893256 scopus 로고    scopus 로고
    • Expression and localization of serotonin receptors in human breast cancer
    • Kopparapu PK, Tinzl M, Anagnostaki L, et al., Expression and localization of serotonin receptors in human breast cancer. Anticancer Res 2013; 33: 363-70.
    • (2013) Anticancer Res , vol.33 , pp. 363-370
    • Kopparapu, P.K.1    Tinzl, M.2    Anagnostaki, L.3
  • 38
    • 0035829691 scopus 로고    scopus 로고
    • Silencing of HTR1B and reduced expression of edn1 in human lung cancers, revealed by methylation-sensitive representational difference analysis
    • Takai D, Yagi Y, Wakazono K, et al., Silencing of HTR1B and reduced expression of edn1 in human lung cancers, revealed by methylation-sensitive representational difference analysis. Oncogene 2001; 20: 7505-13.
    • (2001) Oncogene , vol.20 , pp. 7505-7513
    • Takai, D.1    Yagi, Y.2    Wakazono, K.3
  • 39
    • 84905686310 scopus 로고    scopus 로고
    • Discovery and validation of methylation markers for endometrial cancer
    • Wentzensen N, Bakkum-Gamez JN, Killian JK, et al., Discovery and validation of methylation markers for endometrial cancer. Int J Cancer 2014; 135: 1860-8.
    • (2014) Int J Cancer , vol.135 , pp. 1860-1868
    • Wentzensen, N.1    Bakkum-Gamez, J.N.2    Killian, J.K.3
  • 40
    • 0033840564 scopus 로고    scopus 로고
    • Activation of extracellular signal-regulated kinase (ERK) and akt by human serotonin 5-HT(1B) receptors in transfected BE(2)-C neuroblastoma cells is inhibited by rgs4
    • Leone AM, Errico M, Lin SL, et al., Activation of extracellular signal-regulated kinase (ERK) and akt by human serotonin 5-HT(1B) receptors in transfected BE(2)-C neuroblastoma cells is inhibited by rgs4. J Neurochem 2000; 75: 934-8.
    • (2000) J Neurochem , vol.75 , pp. 934-938
    • Leone, A.M.1    Errico, M.2    Lin, S.L.3
  • 41
    • 80053150200 scopus 로고    scopus 로고
    • Molecular genetics and diagnosis of thyroid cancer
    • Nikiforov YE, Nikiforova MN,. Molecular genetics and diagnosis of thyroid cancer. Nat Rev Endocrinol 2011; 7: 569-80.
    • (2011) Nat Rev Endocrinol , vol.7 , pp. 569-580
    • Nikiforov, Y.E.1    Nikiforova, M.N.2
  • 42
    • 84864280209 scopus 로고    scopus 로고
    • Serotonin activates angiogenic phosphorylation signaling in human endothelial cells
    • Zamani A, Qu Z,. Serotonin activates angiogenic phosphorylation signaling in human endothelial cells. FEBS Lett 2012; 586: 2360-5.
    • (2012) FEBS Lett , vol.586 , pp. 2360-2365
    • Zamani, A.1    Qu, Z.2


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